Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Original Research

Published on 08 Sep 2025

Effect of the autoimmune-associated genetic variant PTPN22 R620W on neutrophil activation and function in patients with insulin-dependent diabetes mellitus

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Eugenia Belcastro
Annamaria Cudini
Irene Mezzani
Stefania Petrini
Valentina D’Oria
Riccardo Schiaffini
Marco Scarsella
Anna Lo Russo
Alessandra Fierabracci

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554570

2,003 views
1 citation

Perspective

Published on 05 Sep 2025

Impact of seasonal cycle on rheumatoid arthritis based on genetic and epigenetic mechanisms

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Krishna Priya E.K
Shidhi P.R
Sreedevi S
Moinak Banerjee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601767

2,649 views
1 citation

Original Research

Published on 05 Sep 2025

Positive associations between triglyceride-glucose (TyG) and TyG-body mass index (TyG-BMI) with cardiovascular disease in patients with psoriasis: cross-sectional results from the SPEECH

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ying Li
Dawei Huang
Biao Ma
Yuxiong Jiang
Bo Yu
Jianfeng Zheng
Yangfeng Ding
Yuling Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644887

2,334 views

Original Research

Published on 05 Sep 2025

Simultaneous profiling of the blood and gut T and B cell repertoires in Crohn’s disease and symptomatic controls illustrates tissue-specific alterations in the immune repertoire of individuals with Crohn’s disease

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Aya K. H. Mahdy
Valentina Schöpfel
Gert Huppertz-Hauss
Gøri Perminow
Florian Tran
Corinna Bang
Johannes R. Hov
May-Bente Bengtson
Petr Ricanek
Randi Opheim

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638522

2,937 views

Review

Published on 05 Sep 2025

Enhancing the treatment potential of IL-17 antagonism in lupus nephritis: finding the right partner

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yingying Gao
Guoyuan Peng
Xin Liu
Xiaochen Ren
Xiaoxiang Chen
Yifan Zhan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1617451

2,847 views

Case Report

Published on 04 Sep 2025

Efgartigimod in the treatment of Guillain-Barré syndrome: case report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Min Deng
Zhaohong Kong
Yan Wang
Xufeng Wang
Tao Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586663

2,540 views

Review

Published on 03 Sep 2025

The role of chemerin, elafin, and visfatin in the pathogenesis of atopic dermatitis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Mateusz Matwiejuk
Agnieszka Kulczyńska-Przybik
Hanna Myśliwiec
Agnieszka Mikłosz
Adrian Chabowski
Barbara Mroczko
Iwona Flisiak

Frontiers in Immunology

doi 10.3389/fimmu.2025.1628163

1,869 views

Case Report

Published on 03 Sep 2025

Guillain-barré syndrome following brainstem infarction: a case report and pathophysiological hypothesis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Shusheng Jiao
Miaomiao Li
Jianxia Zhi
Zengyang Yu
Xiaofang Cheng
Zihua Gong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610219

2,334 views

Review

Published on 03 Sep 2025

Sensing danger in the islet: the roles of pattern recognition receptors in β cells and type 1 diabetes

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Lixiang Tong
Yiting Tu
Shoujun Huang
Peilin Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677177

1,702 views

Original Research

Published on 02 Sep 2025

Developing models for the diagnosing of ulcerative colitis and prognosis of anti-TNF-α non-response based on neutrophil extracellular trap-associated genes

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jinyuan Ou
Linzhen Li
Fachao Zhi
Bing Huang
Xinmei Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530508

2,798 views

Systematic Review

Published on 02 Sep 2025

Anti-MDA5+ dermatomyositis following SARS-COV-2 infections: a systematic review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Simone Lattarulo
Francesca Centrone
Maria Chironna

Frontiers in Immunology

doi 10.3389/fimmu.2025.1565803

4,284 views

Original Research

Published on 02 Sep 2025

Citrullinated peptides of peptidyl arginine deiminase 4 as major B-cell epitopes in patients with rheumatoid arthritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Mathilde Giassi
Eric Toussirot
Nathalie C. Lambert
Jean Roudier
Isabelle Auger

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640291

1,692 views

Review

Published on 02 Sep 2025

Hypoxia and activation of hypoxia inducible factor alpha as influencers of inflammatory helper T cells in autoimmune disease – a link between cancer and autoimmunity

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Giovanni Almanzar
Juan Carlos Alarcon
Ruth Garzon
Ana Maria Navarro
Alejandro Ondo-Méndez
Martina Prelog

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633845

2,582 views

Original Research

Published on 02 Sep 2025

Dysregulated tryptophan metabolism: driving T cell subsets and PI3K-Akt pathway alterations in Hashimoto’s thyroiditis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Lijian Zhang
Xinrui Zhou
Tingwei Cheng
Qiong Wang
Xiaoyan Pei
Lei Yu
Guoxi Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605739

2,281 views
1 citation

Original Research

Published on 02 Sep 2025

Research paper efficacy and safety of telitacicept combined with standard therapy for lupus nephritis: a single-center real-world study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xiaoxia Liu
Na Li
Pengjia Wu
Longyan Qin
Youyang Fan
Jun Liu
Aifei Zhang
Lei Yang
Ting Tian
Jiashun Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645826

2,532 views

Review

Published on 02 Sep 2025

Innate lymphoid cells in the spotlight: from biomarkers to blueprint for innovative immunotherapy

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

I-Chih Kuo
Julyanne Brassard
Peter W. Zandstra
Kelly M. McNagny

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655730

3,387 views
1 citation

Case Report

Published on 01 Sep 2025

Case Report: Fabry disease overlapping with systemic lupus erythematosus in a pediatric patient

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yaqing Liu
Juanjuan Luo
Nengjing Wu
Kaiyuan Luo
Jialing Liu
Liangzhong Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620776

2,930 views

Original Research

Published on 01 Sep 2025

Housekeeping gene dysregulation in psoriasis: integrative multi‐cohort and single‐cell analysis reveals keratinocyte‐centric molecular mechanisms and diagnostic biomarkers

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Hao Tang
Jiacheng Wang
Shuhao Zhang
Guanglong Feng
Xiangshu Cheng
Xin Meng
Rui Chen
Jiaqi Wang
Yongshuai Jiang
Ruijie Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601705

2,211 views

Editorial

Published on 01 Sep 2025

Editorial: Repurposing cancer immunotherapies for use in autoimmunity and transplantation

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Dominic A. Boardman
Lesley A. Smyth
Leonardo M.R. Ferreira

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690655

1,524 views

Original Research

Published on 01 Sep 2025

Clinical value at baseline and follow-up of myeloperoxidase-antibodies in ANCA-associated vasculitis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Gabriel Bossan
Florence Roufosse
Frederic Vandergheynst
Julie Smet
Elie Cogan
Benoit Vokaer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649708

2,850 views

Original Research

Published on 01 Sep 2025

In-silico tool for predicting and scanning rheumatoid arthritis-inducing peptides in an antigen

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Ritu Tomer
Shipra Jain
Pushpendra Singh Gahlot
Nisha Bajiya
Gajendra P. S. Raghava

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630863

2,253 views
1 citation

Review

Published on 01 Sep 2025

Tuberculosis in patients with systemic lupus erythematosus

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jomkwan Ongarj
Porntip Intapiboon
Rachel Tanner
Nawamin Pinpathomrat

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625748

3,194 views
1 citation

Original Research

Published on 29 Aug 2025

Standard dose and low-dose rituximab combined with glucocorticoids and cyclophosphamide in the treatment of acquired haemophilia A

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Mingxia Cai
Xizhe Guo
Xueya Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642982

1,428 views

Systematic Review

Published on 29 Aug 2025

Genetic architecture of primary biliary cholangitis: strong evidence for HLA and non-HLA risk loci

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Min Zhang
Liang Lyu
Liang Ge
Yizhou Wang
Dongqing Gu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600364

2,045 views

2,002 articles

articles

Effect of the autoimmune-associated genetic variant PTPN22 R620W on neutrophil activation and function in patients with insulin-dependent diabetes mellitus

Impact of seasonal cycle on rheumatoid arthritis based on genetic and epigenetic mechanisms

Positive associations between triglyceride-glucose (TyG) and TyG-body mass index (TyG-BMI) with cardiovascular disease in patients with psoriasis: cross-sectional results from the SPEECH

Simultaneous profiling of the blood and gut T and B cell repertoires in Crohn’s disease and symptomatic controls illustrates tissue-specific alterations in the immune repertoire of individuals with Crohn’s disease

Enhancing the treatment potential of IL-17 antagonism in lupus nephritis: finding the right partner

Efgartigimod in the treatment of Guillain-Barré syndrome: case report

The role of chemerin, elafin, and visfatin in the pathogenesis of atopic dermatitis

Guillain-barré syndrome following brainstem infarction: a case report and pathophysiological hypothesis

Sensing danger in the islet: the roles of pattern recognition receptors in β cells and type 1 diabetes

Developing models for the diagnosing of ulcerative colitis and prognosis of anti-TNF-α non-response based on neutrophil extracellular trap-associated genes

Anti-MDA5+ dermatomyositis following SARS-COV-2 infections: a systematic review

Citrullinated peptides of peptidyl arginine deiminase 4 as major B-cell epitopes in patients with rheumatoid arthritis

Hypoxia and activation of hypoxia inducible factor alpha as influencers of inflammatory helper T cells in autoimmune disease – a link between cancer and autoimmunity

Dysregulated tryptophan metabolism: driving T cell subsets and PI3K-Akt pathway alterations in Hashimoto’s thyroiditis

Research paper efficacy and safety of telitacicept combined with standard therapy for lupus nephritis: a single-center real-world study

Innate lymphoid cells in the spotlight: from biomarkers to blueprint for innovative immunotherapy

Case Report: Fabry disease overlapping with systemic lupus erythematosus in a pediatric patient

Housekeeping gene dysregulation in psoriasis: integrative multi‐cohort and single‐cell analysis reveals keratinocyte‐centric molecular mechanisms and diagnostic biomarkers

Editorial: Repurposing cancer immunotherapies for use in autoimmunity and transplantation

Clinical value at baseline and follow-up of myeloperoxidase-antibodies in ANCA-associated vasculitis

In-silico tool for predicting and scanning rheumatoid arthritis-inducing peptides in an antigen

Tuberculosis in patients with systemic lupus erythematosus

Standard dose and low-dose rituximab combined with glucocorticoids and cyclophosphamide in the treatment of acquired haemophilia A

Genetic architecture of primary biliary cholangitis: strong evidence for HLA and non-HLA risk loci