Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Original Research

Accepted on 15 Dec 2025

Upregulation of Interferon-γ Activation in Patients with Anti-Interferon-γ Autoantibodies Immunodeficiency Syndrome: Insights from Single-Cell Analysis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Si-Qiao Liang
Xue-Mei Huang
Xiao-Na Liang
Si-Yao Wu
Li-Mei Hong
Ni Chen
Zeng-Tao Luo
Yan Ning
Meng-Chan Wang
Zhiyi He

Frontiers in Immunology

Review

Published on 15 Dec 2025

Remote patient monitoring in autoimmune related interstitial lung diseases: a narrative review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Malik A. Althobiani
Maryam Almoagal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1643176

334 views

Original Research

Accepted on 12 Dec 2025

Sex-Specific and Socioeconomic Disparities in the Global Burden of Inflammatory Bowel Disease in 204 Countries, 1990–2021: Projections to 2050

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Qingtong Li
Yijie Weng
Yanqi Kou
Chunyi Wu
Rongfo Mi
Wantong Jiang
Yufei Cheng
Lei Ge
Ke Yang
Zhe Huang

Frontiers in Immunology

146 views

Original Research

Published on 12 Dec 2025

Integrated analysis of the relationship between metabolic pathways and immune infiltration in rheumatoid arthritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chaofeng Zhang
Zhongyi You
Zhiqun Pan
Yuming Huang
Zhiming Zhang
Qi Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679356

342 views

Brief Research Report

Published on 12 Dec 2025

Clinical correlation of anti-desmoglein antibody dynamics in pemphigus treated with rituximab

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Vishvan Naidu
Harshita A. Jain
Ali Yalcinkaya
Yathavi Charavanamuttu
Dhruva Biswas
Nadira Ali
John B. Mee
Jitesh Chauhan
Kristina Semkova
Emma C. Benton

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713987

650 views

Conceptual Analysis

Published on 12 Dec 2025

Conceptual quantitative systems pharmacology framework for supporting clinical trial design in organ-specific autoimmune and rare diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Zhengwu Sun
Yalin Xi
Xiaoyan Lan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1714438

251 views

Original Research

Published on 12 Dec 2025

TMEM106A mediates atherosclerosis progression through macrophage-centered immune responses and chemokine signaling

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Menglong Gao
Xingbang Liu
Zhen Fang
Jia Lun
Qingyun Zhang
Yunbo Zhao
Yin Huang
Zhenhua Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681645

368 views

Review

Published on 12 Dec 2025

My cells, my model: immune-competent autologous organ-on-chip systems as a new paradigm in precision medicine

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Francesco Bisconti
Hugo Abreu
Thuy Duong Nguyen
Fabiola Stolfi
Noemi Corbezzolo
Giuseppe Gigli
Davide Raineri
Giuseppe Cappellano
Alessandro Polini
Francesca Gervaso

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712796

703 views

Mini Review

Accepted on 11 Dec 2025

Signaling pathways in systemic lupus erythematosus and therapeutic implications

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Lili Balogh
Viktor Kovács
Gyorgy Nagy
Tamas Nemeth

Frontiers in Immunology

134 views

Editorial

Accepted on 11 Dec 2025

Editorial: How Underappreciated Autoinflammatory Mechanisms (Innate Immunity) Dominate Disparate Autoimmune Disorders

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Qiao Zhou
Yue Yang
Dennis McGonagle

Frontiers in Immunology

227 views

Systematic Review

Accepted on 11 Dec 2025

Curcumin for the clinical treatment of rheumatoid arthritis: a systematic review and meta-analysis of placebo-controlled randomized clinical trials

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yihua Fan
Zhiqiang Yi
Shijie Mao
Jialu Wen
Jiwei Zhang
Qiang Zhang
Ruihan Liu

Frontiers in Immunology

160 views

Case Report

Accepted on 11 Dec 2025

Pemphigus vegetans successfully treated with systemic corticosteroid and rituximab: A rare case report with 15-month follow-up and literature review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Hongyan Ji
Liuqing Chen
Jinbo Chen

Frontiers in Immunology

Original Research

Published on 11 Dec 2025

Autoantibodies in long COVID in a black/mixed population compared with recovered and pre-pandemic controls

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jessica de Jesus Silva
Laila Sampaio Horta
Sayonara Melo Viana
Ana Beatriz Cazé
Isabela S. Oliveira
Mariana M. Pereira
Natalie Antas Nascimento
Blenda de Jesus Pereira
Ícaro Bonyek-Silva
Sara Nunes de Oliveira Araújo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684482

423 views

Original Research

Published on 11 Dec 2025

Risk factors for central hypoventilation in anti-N-methyl-D-aspartate receptor encephalitis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xuan Zou
Xi-yue Jing
Guan-en Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718192

249 views

Review

Accepted on 10 Dec 2025

Autoimmune Disease-Associated Lymphomas: Research Progress and Review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chengqian Chen
Wei Guo
Yangzhi Zhao
XINGTONG WANG
Jia Li
Ying Zhang
Zhaoxia Li
Haotian Wang
Ou Bai

Frontiers in Immunology

230 views

Case Report

Accepted on 10 Dec 2025

Epidermolysis bullosa acquisita following dipeptidyl peptidase-4 inhibitor therapy and complicated by immune thrombocytopenic purpura

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Hirofumi Kawamoto
Natsuko Sasaki
Yukimi Ueda
Norito Ishii
Yu Sawada

Frontiers in Immunology

108 views

Original Research

Accepted on 10 Dec 2025

Multiplex Autoantibody Screening in Pediatric Type 1 Diabetes: POC Blot vs. ELISA for Gluten-Related Disorders

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Adugna Gudeta Negussie
Patricia Wusterhausen
Dassalegn Muleta
Demise Mulugeta
Mesfin Bekele
Torsten Matthias

Frontiers in Immunology

Review

Published on 10 Dec 2025

Progress in the preparation of an active immunization model of anti-N-methyl-D-aspartate receptor encephalitis in animals

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Kuikui Zeng
Yuting Liu
Sai Yang
Lingjuan Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585353

383 views

Original Research

Published on 10 Dec 2025

Cytokine-driven glycosphingolipid metabolism modulates endoplasmic reticulum calcium homeostasis in primary human renal mesangial cells

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Mariia Stefanenko
Tessa M. Ortiz
Sandra G. Mungaray
Mykhailo Fedoriuk
Oleg Palygin
Stefano Berto
Drew Moore
Tamara K. Nowling

Frontiers in Immunology

doi 10.3389/fimmu.2025.1688916

408 views

Original Research

Published on 10 Dec 2025

Fibroblast-like synoviocytes mediate the generation of soluble PD-1 in an MMP-9-dependent manner: a novel target therapy for rheumatoid arthritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chao Yang
Miao Ma
Kangjie Yu
Yi Wang
Yuting Zhang
Yan Shen
Jun Wang
Xiaoke Wang
Lulu Luo
Ya Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665078

398 views

Case Report

Published on 10 Dec 2025

Case Report: The case of atypical OAPS complicated by positive anti-SSA and anti-SSB antibodies

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chunyan Huang
Daorong Hong
Xiaoqing Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631323

227 views

Case Report

Published on 10 Dec 2025

MRI-negative myelitis, especially after COVID-19: a case report and literature review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Mitsuyoshi Tamura
Yohei Yagi
Satoki Hanayama
Satoko Yoshizaki
Kazumoto Shibuya
Hiroki Masuda
Masahiro Mori

Frontiers in Immunology

doi 10.3389/fimmu.2025.1708018

420 views

Original Research

Published on 10 Dec 2025

Impact of celiac disease on patients with familial Mediterranean fever: a nationwide study based on the Türkiye database

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Rıfat Bozkuş
Serdar Can Güven
Salih Başer
Nuray Yılmaz Çakmak
Hasan Satış
Emin Gemcioğlu
Naim Ata
Şuayip Birinci

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675131

346 views

Original Research

Accepted on 09 Dec 2025

Fc-enhanced anti-CCR6 antibody elicits Robust Therapeutic Effects Across Multiple Autoimmune Diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Md Jahangir Alam
Yu-Anne Yap
Caroline Ang
Liang Xie
Hillary L. Shane
Charles R. Mackay
Remy Robert

Frontiers in Immunology

223 views

1,960 articles

articles

Upregulation of Interferon-γ Activation in Patients with Anti-Interferon-γ Autoantibodies Immunodeficiency Syndrome: Insights from Single-Cell Analysis

Remote patient monitoring in autoimmune related interstitial lung diseases: a narrative review

Sex-Specific and Socioeconomic Disparities in the Global Burden of Inflammatory Bowel Disease in 204 Countries, 1990–2021: Projections to 2050

Integrated analysis of the relationship between metabolic pathways and immune infiltration in rheumatoid arthritis

Clinical correlation of anti-desmoglein antibody dynamics in pemphigus treated with rituximab

Conceptual quantitative systems pharmacology framework for supporting clinical trial design in organ-specific autoimmune and rare diseases

TMEM106A mediates atherosclerosis progression through macrophage-centered immune responses and chemokine signaling

My cells, my model: immune-competent autologous organ-on-chip systems as a new paradigm in precision medicine

Signaling pathways in systemic lupus erythematosus and therapeutic implications

Editorial: How Underappreciated Autoinflammatory Mechanisms (Innate Immunity) Dominate Disparate Autoimmune Disorders

Curcumin for the clinical treatment of rheumatoid arthritis: a systematic review and meta-analysis of placebo-controlled randomized clinical trials

Pemphigus vegetans successfully treated with systemic corticosteroid and rituximab: A rare case report with 15-month follow-up and literature review

Autoantibodies in long COVID in a black/mixed population compared with recovered and pre-pandemic controls

Risk factors for central hypoventilation in anti-N-methyl-D-aspartate receptor encephalitis

Autoimmune Disease-Associated Lymphomas: Research Progress and Review

Epidermolysis bullosa acquisita following dipeptidyl peptidase-4 inhibitor therapy and complicated by immune thrombocytopenic purpura

Multiplex Autoantibody Screening in Pediatric Type 1 Diabetes: POC Blot vs. ELISA for Gluten-Related Disorders

Progress in the preparation of an active immunization model of anti-N-methyl-D-aspartate receptor encephalitis in animals

Cytokine-driven glycosphingolipid metabolism modulates endoplasmic reticulum calcium homeostasis in primary human renal mesangial cells

Fibroblast-like synoviocytes mediate the generation of soluble PD-1 in an MMP-9-dependent manner: a novel target therapy for rheumatoid arthritis

Case Report: The case of atypical OAPS complicated by positive anti-SSA and anti-SSB antibodies

MRI-negative myelitis, especially after COVID-19: a case report and literature review

Impact of celiac disease on patients with familial Mediterranean fever: a nationwide study based on the Türkiye database

Fc-enhanced anti-CCR6 antibody elicits Robust Therapeutic Effects Across Multiple Autoimmune Diseases