Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Original Research

Published on 21 Oct 2025

The effect of baricitinib on pSTAT3 levels in IL-6- or IL-15-stimulated PBMCs isolated from patients with SLE

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Gábor J. Szebeni
Nikolett Gémes
Patrícia Neuperger
Enikő Szabó
József Á. Balog
Dániel Honfi
Attila Balog
Gergely Toldi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675350

1,821 views

Case Report

Published on 10 Oct 2025

A case report of plaque psoriasis comorbid with hidradenitis suppurativa, hepatitis B, and colorectal cancer treated with xeligekimab

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Jun Ma
Binbin Hu
Jiayao Pan
Lunfei Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651568

9,179 views

Original Research

Published on 09 Oct 2025

Ultra-processed food intake is associated with increased gastrointestinal tract symptoms and alterations in gut microbiota in patients with systemic sclerosis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ju Young Lee
Swapna Mahurkar-Joshi
Arissa Young
Jennifer S. Labus
Bofei He
Ezinne Aja
Jonathan P. Jacobs
Elizabeth R. Volkmann

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610360

2,096 views

Original Research

Published on 08 Oct 2025

Atherosclerotic cardiovascular disease and mortality in a cohort of patients with rheumatoid arthritis: a prospective study investigating microRNAs as predictors of atherosclerosis and mortality

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Dídac Llop
Silvia Paredes
Daiana Ibarretxe
Roser Rosales
Lluís Masana
Josep Ribalta
Joan Carles Vallvé

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667553

1,594 views

Review

Published on 03 Oct 2025

Polymorphism-driven immune disruptions in Kawasaki disease across populations: decoding the role of T and B-cells

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Chu Zhang
Lu Wang
Qihong Fan
Yan Pan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640024

1,789 views
1 citation

Case Report

Published on 03 Oct 2025

Case Report: Mevalonate kinase deficiency: an underdiagnosed cause of ischemic stroke—characterization of a novel genetic variant

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Lyna-Nour Hamidi
Jack Christopher Drda
Meriem Belhocine
Hannah-Laure Elfassy
Stéphanie Ducharme-Bénard
Maxime Chayer-Lanthier
Bushra Sultana
Sylvain Lanthier

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651819

2,082 views

Opinion

Published on 30 Sep 2025

The immunological mechanisms linking systemic lupus erythematosus and neuropsychiatric disorders

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Shiuan‐Tzuen Su
Poi Kuo
Po-Cheng Shih
James C. - C. Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651874

2,128 views

Original Research

Published on 29 Sep 2025

Value of dynamic changes in inflammatory biomarkers for predicting intravenous immunoglobulin resistance in children with Kawasaki disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Zhiyuan Liu
Yidan Zhang
PanPan Liu
Weiguo Qian
Qiuqin Xu
Miao Hou
Ying Liu
Guanghui Qian
Jiajia Tan
Qianzi Ge

Frontiers in Immunology

doi 10.3389/fimmu.2025.1632578

1,998 views

Original Research

Published on 25 Sep 2025

Impact of hypercoagulable state on Crohn’s disease severity and progression: transcriptomic and single-cell analyses of the ileum

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Fengfei Wu
Fangting Wu
Hui Yang
Wenting Xie
Sinan Zhang
Lihua Zhou
Fang Xie
Lan Bai
Miaoxing Huang
Side Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611114

1,472 views

Original Research

Published on 25 Sep 2025

Eculizumab for the acute attack of neuromyelitis optica spectrum disorder

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Qingqing Zhuang
Wenjuan Huang
Jingzi ZhangBao
Zhouzhou Wang
Lei Zhou
Xiang Li
Yuxin Fan
Liang Wang
Yiqin Xiao
Jian Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645401

2,921 views

Original Research

Published on 23 Sep 2025

Drug-induced Sweet’s syndrome: pharmacovigilance insights from FAERS with a cross-database consistency assessment in VigiBase via LASSO and multivariable logistic regression

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yuhan Xie
Qinxiao Li
Jing Zhou
Xiangqi Qin
Zhe Zhang
Ruimin Bai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622736

2,405 views

Original Research

Published on 19 Sep 2025

A two-transcript classifier model of host genes for discrimination of bacterial from viral infection in ulcerative colitis with opportunistic infections: a discovery and validation study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Huipeng Zhang
Nannan Xu
Ahemala Duishanbai
Gang Huang
Jing Zhang
Guanwei Bi
Manyu Li
Gang Wang
Yanbo Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642923

1,500 views

Systematic Review

Published on 18 Sep 2025

Efficacy and safety of IL-17, IL-12/23, and IL-23 inhibitors for psoriatic arthritis: a network meta-analysis of randomized controlled trials

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Shan Gao
Xingxing Xie
Ling Fan
Linyuan Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654343

6,686 views
1 citation

Original Research

Published on 17 Sep 2025

Impact of temperature trend-defined seasonality on psoriasis treatment outcomes: a multicenter longitudinal study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xinyi Song
Qin Yang
Yuye Wang
Ning Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641225

2,264 views

Review

Published on 17 Sep 2025

The role of the tuft cell–interleukin-25 axis in the pathogenesis of inflammatory bowel disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Zishao Tao
Li Li
Ying Zhang
Yufang Tang
Simeng Zhang
Heying Yang
Guorong Jiang
Rui Zhang
Zhiwei Wu
Miao He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629060

3,934 views
1 citation

Original Research

Published on 15 Sep 2025

The diverse N-glycosylation profiles of CD4+CD25- and CD4+CD25+ T cells in Hashimoto’s thyroiditis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Sara Trzos
Marta Szewczyk
Paweł Link-Lenczowski
Grzegorz Sokołowski
Małgorzata Trofimiuk-Müldner
Katarzyna Bocian
Ewa Pocheć

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633344

1,814 views

Mini Review

Published on 15 Sep 2025

STING-targeting PROTACs: emerging therapeutic tools for enhanced immunotherapy in inflammatory diseases

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Wenqing Jiang
Xiaoping Yang
Huiying Liu
Chao Wang
Hongxin Niu
Wanpeng Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631132

2,851 views

Review

Published on 12 Sep 2025

Decoding the inflammatory-osteogenic axis in ankylosing spondylitis: mechanisms, dysregulation, and emerging therapeutic interventions

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Afroza Parvin
Ashish Ranjan Sharma
Md. Ashraful Hasan
Garima Sharma
Mohammad Mahfuz Ali Khan Shawan
Eun Min Seo
Md. Mahmudul Hasan
Sang-Soo Lee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633318

3,190 views

Original Research

Published on 11 Sep 2025

A splicing-based multitissue association study of joint transcriptomes identified susceptibility genes for osteoarthritis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Lantao Zhang
Fuxing Zhao
Hengheng Zhang
Xingbang Niu
Youliang Li
Chunxia Zhao
Jianhua Ding
Chaozheng Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590008

1,923 views

Case Report

Published on 10 Sep 2025

Cutaneous mucormycosis in systemic lupus erythematosus: a case report

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Shiyang Li
Ting Meng
Yuqiu Lin
Dong Xie
Zhihua Li
Qing Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602639

1,569 views

Systematic Review

Published on 10 Sep 2025

Association of FCGR2A rs1801274 and FCGR3A rs396991 polymorphisms with various autoimmune diseases: a meta-analysis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Elena Thaler
Maike Bublitz
Martin Wipplinger
Christoph Gassner
Hanno Ulmer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661502

2,113 views
1 citation

Original Research

Published on 09 Sep 2025

Cytotoxic T lymphocyte-associated protein 4 gene polymorphisms are associated with ANCA-associated vasculitis in the Guangxi population of China

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Kunpeng Bu
Binglan Yang
Peigeng He
Chao Xue

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631088

1,183 views

Brief Research Report

Published on 05 Sep 2025

Severe fatigue is associated with diminished lung function and elevated Galectin-9 levels in early systemic sclerosis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Charmaine van Eeden
Maryam Rezaeifar
Muhammad Elezzabi
Desiree Redmond
Robert Gniadecki
Andrew Abey
Erin Reynolds
Dalton Sholter
Shima Shahbaz
Shokrollah Elahi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655414

2,307 views

Original Research

Published on 04 Sep 2025

Novel USP18 mutations lead to severe interferonopathy responsive to JAK inhibitor

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xiangwei Sun
Ming Li
Yiying Dou
Qintao Wang
Jianming Lai
Jia Zhu
Qing Zhou
Xiaomin Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646996

1,995 views

513 articles

articles

The effect of baricitinib on pSTAT3 levels in IL-6- or IL-15-stimulated PBMCs isolated from patients with SLE

A case report of plaque psoriasis comorbid with hidradenitis suppurativa, hepatitis B, and colorectal cancer treated with xeligekimab

Ultra-processed food intake is associated with increased gastrointestinal tract symptoms and alterations in gut microbiota in patients with systemic sclerosis

Atherosclerotic cardiovascular disease and mortality in a cohort of patients with rheumatoid arthritis: a prospective study investigating microRNAs as predictors of atherosclerosis and mortality

Polymorphism-driven immune disruptions in Kawasaki disease across populations: decoding the role of T and B-cells

Case Report: Mevalonate kinase deficiency: an underdiagnosed cause of ischemic stroke—characterization of a novel genetic variant

The immunological mechanisms linking systemic lupus erythematosus and neuropsychiatric disorders

Value of dynamic changes in inflammatory biomarkers for predicting intravenous immunoglobulin resistance in children with Kawasaki disease

Impact of hypercoagulable state on Crohn’s disease severity and progression: transcriptomic and single-cell analyses of the ileum

Eculizumab for the acute attack of neuromyelitis optica spectrum disorder

Drug-induced Sweet’s syndrome: pharmacovigilance insights from FAERS with a cross-database consistency assessment in VigiBase via LASSO and multivariable logistic regression

A two-transcript classifier model of host genes for discrimination of bacterial from viral infection in ulcerative colitis with opportunistic infections: a discovery and validation study

Efficacy and safety of IL-17, IL-12/23, and IL-23 inhibitors for psoriatic arthritis: a network meta-analysis of randomized controlled trials

Impact of temperature trend-defined seasonality on psoriasis treatment outcomes: a multicenter longitudinal study

The role of the tuft cell–interleukin-25 axis in the pathogenesis of inflammatory bowel disease

The diverse N-glycosylation profiles of CD4+CD25- and CD4+CD25+ T cells in Hashimoto’s thyroiditis

STING-targeting PROTACs: emerging therapeutic tools for enhanced immunotherapy in inflammatory diseases

Decoding the inflammatory-osteogenic axis in ankylosing spondylitis: mechanisms, dysregulation, and emerging therapeutic interventions

A splicing-based multitissue association study of joint transcriptomes identified susceptibility genes for osteoarthritis

Cutaneous mucormycosis in systemic lupus erythematosus: a case report

Association of FCGR2A rs1801274 and FCGR3A rs396991 polymorphisms with various autoimmune diseases: a meta-analysis

Cytotoxic T lymphocyte-associated protein 4 gene polymorphisms are associated with ANCA-associated vasculitis in the Guangxi population of China

Severe fatigue is associated with diminished lung function and elevated Galectin-9 levels in early systemic sclerosis

Novel USP18 mutations lead to severe interferonopathy responsive to JAK inhibitor