Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Original Research

Published on 29 Oct 2025

Immune function analysis in a pediatric patient with a de novo ALPK1 gene mutation

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xue Chuan
Aiyan Ren
Shiyue Hu
Qian Li
Yin Zhu
Pingping Zhang
Lin Wang
Qing Du
Hong Li
Yan Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622079

1,926 views

Original Research

Published on 29 Oct 2025

Uncovering the molecular and immunological defects in multicentric carpotarsal osteolysis syndrome: identification of relevant biomarkers

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Dorra Najjar
Asma Chikhaoui
Rim Boussetta
Saifeddine Azouz
Sinda Zarrouk
Sami Bouchoucha
Houda Yacoub-Youssef

Frontiers in Immunology

doi 10.3389/fimmu.2025.1543385

1,591 views

Review

Published on 28 Oct 2025

Cerebral rheumatoid vasculitis: an integrated analysis of case presentation, literature review, and prognostic stratification

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yinghui Zhang
Xuefeng Zhai
Li Ning
Juan Yang
Liu Yang
Jian Li
Shuhong Chi
Boya Ma
Liu Lu
Zhao Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683920

1,765 views

Brief Research Report

Published on 27 Oct 2025

Sex-specific metabolic effects of Treg expansion in db/db mice

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Daniel Pérez-Martínez
María Jose Canz
Elisabet Torras-Peyrotón
Anna Alvarez-Guaita
Lorena Ramos-Pérez
Cristina Hernández
Rafael Simó
María Llorián-Salvador

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599985

1,740 views
1 citation

Case Report

Published on 27 Oct 2025

Case Report: IgG4-related ophthalmic disease presenting with unilateral proptosis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xiaodong Li
Xuewei Qin
Mei Chen
Xi Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652730

2,325 views

Original Research

Published on 24 Oct 2025

The role of NFKB1 and NFKBIA in immunoglobulin A vasculitis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Joao Carlos Batista-Liz
María Sebastián Mora-Gil
Mónica Renuncio García
María Teresa Leonardo
Ana Peñalba
Ligia Gabrie
Rafael Gálvez Sánchez
Luis Martín-Penagos
Javier Narvaez
Belén Sevilla-Pérez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692908

1,834 views
1 citation

Original Research

Published on 23 Oct 2025

Myelin oligodendrocyte glycoprotein antibody-associated isolated aseptic meningitis: a single−center pediatric case series

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Kang Liu
Suzhen Sun
Fang Chen
Wenjuan Wu
Xin Li
Lingyu Pang
Wei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1699683

1,766 views

Original Research

Published on 22 Oct 2025

Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ling Kui
Jinqun Huang
Guoyun Wang
Jiamin Zhao
Shuangshuang Wang
Xiaoxing Qin
Leifeng Liu
Jianfei Hu
Lianjia Chen
Xingchun Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667195

3,205 views

Original Research

Published on 22 Oct 2025

Clinical study of PLA2R epitope spreading for predicting proteinuria remission in primary membranous nephropathy

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xueyang Cheng
Meiyi Zhou
Caimei Chen
Jing Xue
Bin Liu
Zhijian Zhang
Xiran Zhang
Leting Zhou
Ting Cai
Biao Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685738

1,879 views

Original Research

Published on 21 Oct 2025

The effect of baricitinib on pSTAT3 levels in IL-6- or IL-15-stimulated PBMCs isolated from patients with SLE

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Gábor J. Szebeni
Nikolett Gémes
Patrícia Neuperger
Enikő Szabó
József Á. Balog
Dániel Honfi
Attila Balog
Gergely Toldi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675350

2,419 views
1 citation

Case Report

Published on 10 Oct 2025

A case report of plaque psoriasis comorbid with hidradenitis suppurativa, hepatitis B, and colorectal cancer treated with xeligekimab

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Jun Ma
Binbin Hu
Jiayao Pan
Lunfei Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651568

9,726 views

Original Research

Published on 09 Oct 2025

Ultra-processed food intake is associated with increased gastrointestinal tract symptoms and alterations in gut microbiota in patients with systemic sclerosis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ju Young Lee
Swapna Mahurkar-Joshi
Arissa Young
Jennifer S. Labus
Bofei He
Ezinne Aja
Jonathan P. Jacobs
Elizabeth R. Volkmann

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610360

2,807 views

Original Research

Published on 08 Oct 2025

Atherosclerotic cardiovascular disease and mortality in a cohort of patients with rheumatoid arthritis: a prospective study investigating microRNAs as predictors of atherosclerosis and mortality

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Dídac Llop
Silvia Paredes
Daiana Ibarretxe
Roser Rosales
Lluís Masana
Josep Ribalta
Joan Carles Vallvé

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667553

1,923 views

Review

Published on 03 Oct 2025

Polymorphism-driven immune disruptions in Kawasaki disease across populations: decoding the role of T and B-cells

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Chu Zhang
Lu Wang
Qihong Fan
Yan Pan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640024

2,267 views
1 citation

Case Report

Published on 03 Oct 2025

Case Report: Mevalonate kinase deficiency: an underdiagnosed cause of ischemic stroke—characterization of a novel genetic variant

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Lyna-Nour Hamidi
Jack Christopher Drda
Meriem Belhocine
Hannah-Laure Elfassy
Stéphanie Ducharme-Bénard
Maxime Chayer-Lanthier
Bushra Sultana
Sylvain Lanthier

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651819

2,500 views

Opinion

Published on 30 Sep 2025

The immunological mechanisms linking systemic lupus erythematosus and neuropsychiatric disorders

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Shiuan‐Tzuen Su
Poi Kuo
Po-Cheng Shih
James C. - C. Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651874

2,677 views

Original Research

Published on 29 Sep 2025

Value of dynamic changes in inflammatory biomarkers for predicting intravenous immunoglobulin resistance in children with Kawasaki disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Zhiyuan Liu
Yidan Zhang
PanPan Liu
Weiguo Qian
Qiuqin Xu
Miao Hou
Ying Liu
Guanghui Qian
Jiajia Tan
Qianzi Ge

Frontiers in Immunology

doi 10.3389/fimmu.2025.1632578

2,292 views

Original Research

Published on 25 Sep 2025

Eculizumab for the acute attack of neuromyelitis optica spectrum disorder

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Qingqing Zhuang
Wenjuan Huang
Jingzi ZhangBao
Zhouzhou Wang
Lei Zhou
Xiang Li
Yuxin Fan
Liang Wang
Yiqin Xiao
Jian Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645401

3,811 views
1 citation

Original Research

Published on 25 Sep 2025

Impact of hypercoagulable state on Crohn’s disease severity and progression: transcriptomic and single-cell analyses of the ileum

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Fengfei Wu
Fangting Wu
Hui Yang
Wenting Xie
Sinan Zhang
Lihua Zhou
Fang Xie
Lan Bai
Miaoxing Huang
Side Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611114

1,905 views

Original Research

Published on 23 Sep 2025

Drug-induced Sweet’s syndrome: pharmacovigilance insights from FAERS with a cross-database consistency assessment in VigiBase via LASSO and multivariable logistic regression

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yuhan Xie
Qinxiao Li
Jing Zhou
Xiangqi Qin
Zhe Zhang
Ruimin Bai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622736

2,953 views
1 citation

Original Research

Published on 19 Sep 2025

A two-transcript classifier model of host genes for discrimination of bacterial from viral infection in ulcerative colitis with opportunistic infections: a discovery and validation study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Huipeng Zhang
Nannan Xu
Ahemala Duishanbai
Gang Huang
Jing Zhang
Guanwei Bi
Manyu Li
Gang Wang
Yanbo Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642923

1,815 views

Systematic Review

Published on 18 Sep 2025

Efficacy and safety of IL-17, IL-12/23, and IL-23 inhibitors for psoriatic arthritis: a network meta-analysis of randomized controlled trials

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Shan Gao
Xingxing Xie
Ling Fan
Linyuan Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654343

9,323 views
5 citations

Original Research

Published on 17 Sep 2025

Impact of temperature trend-defined seasonality on psoriasis treatment outcomes: a multicenter longitudinal study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xinyi Song
Qin Yang
Yuye Wang
Ning Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641225

2,777 views

Review

Published on 17 Sep 2025

The role of the tuft cell–interleukin-25 axis in the pathogenesis of inflammatory bowel disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Zishao Tao
Li Li
Ying Zhang
Yufang Tang
Simeng Zhang
Heying Yang
Guorong Jiang
Rui Zhang
Zhiwei Wu
Miao He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629060

5,238 views
1 citation

546 articles

articles

Immune function analysis in a pediatric patient with a de novo ALPK1 gene mutation

Uncovering the molecular and immunological defects in multicentric carpotarsal osteolysis syndrome: identification of relevant biomarkers

Cerebral rheumatoid vasculitis: an integrated analysis of case presentation, literature review, and prognostic stratification

Sex-specific metabolic effects of Treg expansion in db/db mice

Case Report: IgG4-related ophthalmic disease presenting with unilateral proptosis

The role of NFKB1 and NFKBIA in immunoglobulin A vasculitis

Myelin oligodendrocyte glycoprotein antibody-associated isolated aseptic meningitis: a single−center pediatric case series

Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice

Clinical study of PLA2R epitope spreading for predicting proteinuria remission in primary membranous nephropathy

The effect of baricitinib on pSTAT3 levels in IL-6- or IL-15-stimulated PBMCs isolated from patients with SLE

A case report of plaque psoriasis comorbid with hidradenitis suppurativa, hepatitis B, and colorectal cancer treated with xeligekimab

Ultra-processed food intake is associated with increased gastrointestinal tract symptoms and alterations in gut microbiota in patients with systemic sclerosis

Atherosclerotic cardiovascular disease and mortality in a cohort of patients with rheumatoid arthritis: a prospective study investigating microRNAs as predictors of atherosclerosis and mortality

Polymorphism-driven immune disruptions in Kawasaki disease across populations: decoding the role of T and B-cells

Case Report: Mevalonate kinase deficiency: an underdiagnosed cause of ischemic stroke—characterization of a novel genetic variant

The immunological mechanisms linking systemic lupus erythematosus and neuropsychiatric disorders

Value of dynamic changes in inflammatory biomarkers for predicting intravenous immunoglobulin resistance in children with Kawasaki disease

Eculizumab for the acute attack of neuromyelitis optica spectrum disorder

Impact of hypercoagulable state on Crohn’s disease severity and progression: transcriptomic and single-cell analyses of the ileum

Drug-induced Sweet’s syndrome: pharmacovigilance insights from FAERS with a cross-database consistency assessment in VigiBase via LASSO and multivariable logistic regression

A two-transcript classifier model of host genes for discrimination of bacterial from viral infection in ulcerative colitis with opportunistic infections: a discovery and validation study

Efficacy and safety of IL-17, IL-12/23, and IL-23 inhibitors for psoriatic arthritis: a network meta-analysis of randomized controlled trials

Impact of temperature trend-defined seasonality on psoriasis treatment outcomes: a multicenter longitudinal study

The role of the tuft cell–interleukin-25 axis in the pathogenesis of inflammatory bowel disease