Frontiers in Immunology | Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Original Research

Published on 15 Sep 2025

The diverse N-glycosylation profiles of CD4+CD25- and CD4+CD25+ T cells in Hashimoto’s thyroiditis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Sara Trzos
Marta Szewczyk
Paweł Link-Lenczowski
Grzegorz Sokołowski
Małgorzata Trofimiuk-Müldner
Katarzyna Bocian
Ewa Pocheć

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633344

2,176 views

Mini Review

Published on 15 Sep 2025

STING-targeting PROTACs: emerging therapeutic tools for enhanced immunotherapy in inflammatory diseases

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Wenqing Jiang
Xiaoping Yang
Huiying Liu
Chao Wang
Hongxin Niu
Wanpeng Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631132

3,715 views
1 citation

Review

Published on 12 Sep 2025

Decoding the inflammatory-osteogenic axis in ankylosing spondylitis: mechanisms, dysregulation, and emerging therapeutic interventions

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Afroza Parvin
Ashish Ranjan Sharma
Md. Ashraful Hasan
Garima Sharma
Mohammad Mahfuz Ali Khan Shawan
Eun Min Seo
Md. Mahmudul Hasan
Sang-Soo Lee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633318

4,057 views

Original Research

Published on 11 Sep 2025

A splicing-based multitissue association study of joint transcriptomes identified susceptibility genes for osteoarthritis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Lantao Zhang
Fuxing Zhao
Hengheng Zhang
Xingbang Niu
Youliang Li
Chunxia Zhao
Jianhua Ding
Chaozheng Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590008

2,356 views

Case Report

Published on 10 Sep 2025

Cutaneous mucormycosis in systemic lupus erythematosus: a case report

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Shiyang Li
Ting Meng
Yuqiu Lin
Dong Xie
Zhihua Li
Qing Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602639

1,850 views

Systematic Review

Published on 10 Sep 2025

Association of FCGR2A rs1801274 and FCGR3A rs396991 polymorphisms with various autoimmune diseases: a meta-analysis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Elena Thaler
Maike Bublitz
Martin Wipplinger
Christoph Gassner
Hanno Ulmer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661502

2,798 views
2 citations

Original Research

Published on 09 Sep 2025

Cytotoxic T lymphocyte-associated protein 4 gene polymorphisms are associated with ANCA-associated vasculitis in the Guangxi population of China

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Kunpeng Bu
Binglan Yang
Peigeng He
Chao Xue

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631088

1,474 views

Brief Research Report

Published on 05 Sep 2025

Severe fatigue is associated with diminished lung function and elevated Galectin-9 levels in early systemic sclerosis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Charmaine van Eeden
Maryam Rezaeifar
Muhammad Elezzabi
Desiree Redmond
Robert Gniadecki
Andrew Abey
Erin Reynolds
Dalton Sholter
Shima Shahbaz
Shokrollah Elahi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655414

2,799 views

Original Research

Published on 04 Sep 2025

Novel USP18 mutations lead to severe interferonopathy responsive to JAK inhibitor

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xiangwei Sun
Ming Li
Yiying Dou
Qintao Wang
Jianming Lai
Jia Zhu
Qing Zhou
Xiaomin Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646996

2,532 views

Review

Published on 03 Sep 2025

Overlapping features of atopic dermatitis and alopecia areata: from pathogenesis to treatment

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Jiayi Cheng
Yugu Jiang
Qianqian Chen
Min Xiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641918

4,445 views

Case Report

Published on 02 Sep 2025

Case Report: Acute onset hemiparesis in a young man: do not miss Crohn’s disease

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Virginia Iacobelli
Simone Tagliabue
Beatrice Modello
Daniele Velardo
Elena Abati
Fabio Triulzi
Giacomo Pietro Comi
Stefania Corti
Delia Gagliardi
Mosè Parisi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662213

2,017 views

Brief Research Report

Published on 02 Sep 2025

Assessment of gene signatures following the inhibition of IL-23: a study to evaluate the mechanistic effects behind the clinical efficacy of guselkumab in patients with psoriatic arthritis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Mirco Mastrangelo
Piero Ruscitti
Manfredo Bruni
Eleonora Lucantonio
Andrea De Berardinis
Antonio Barile
Maria Concetta Fargnoli
Paola Cipriani
Maria Esposito
Cristina Pellegrini

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672667

2,957 views

Original Research

Published on 29 Aug 2025

Exploring the interplay of prolactin and bromocriptine on serum markers in granulomatous lobular mastitis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Binheng Liu
Wenchao Qu
Yi Feng
Xueqing Wu
Jiamei Feng
Qingqian Gao
Shijun Shao
Jiaye Sun
Hua Wan
Weiping Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608875

2,765 views

Original Research

Published on 29 Aug 2025

Hypocomplementemia dynamics during tocilizumab therapy in systemic juvenile idiopathic arthritis: a retrospective longitudinal study

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Jiayun Ling
Qingfang Zhou
Fang Xie
Xiaohui Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607101

1,886 views

Case Report

Published on 27 Aug 2025

The utilization of efgartigimod in the treatment of acute cerebellar ataxia: a case report

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Liu L. Yang
Yushuang Ruan
Fucheng Cai
Yuanpeng Xia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1581954

3,182 views

Review

Published on 27 Aug 2025

Pediatric inflammatory bowel disease and cancer

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Jia-Jing Zheng
Zhi-Fei Wu
Yi-Bing Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624177

3,679 views

Case Report

Published on 26 Aug 2025

Misfortunes never come alone: melanoma and ulcerative colitis after biologic therapy in a psoriatic patient – a case report and literature review

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Aleksandra Wiktoria Bratborska
Magdalena Jałowska
Monika Bowszyc-Dmochowska
Michał J. Kowalczyk
Kinga Adamska

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651517

4,172 views
1 citation

Brief Research Report

Published on 25 Aug 2025

Adult onset cryopyrin-associated periodic syndrome due to germline missense mutation in NLRP3 in a previously healthy middle-aged woman

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Sung Ik Cho
Sheehyun Kim
Ju Yeon Kim
Jeong-Won Kim
Sujin Pyeon
Won-Woo Lee
Jin Kyun Park

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652177

2,903 views

Review

Published on 21 Aug 2025

Novel advances on pathophysiological mechanisms, clinical manifestations, and treatment of antiphospholipid syndrome

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Qing-Nan Zhu
Xiang-Bo Qi
Shu-Wei Ren
Yu-Ye Li
Ze-Wen Yan
Yu Sun
Yan Shi
Qing-Si Wen
Mao-Mao Wu
Da-Peng Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639065

7,238 views
2 citations

Original Research

Published on 21 Aug 2025

Antibodies against integrin αvβ6 have high diagnostic accuracy for ulcerative colitis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Patrick Bez
Martina Scapolan
Davide Giuseppe Ribaldone
Gian Paolo Caviglia
Silvia Zago
Cristina Trucco
Simone Frara
Antonino Caruso
Marta Ascolani
Michele Campigotto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641329

3,863 views
1 citation

Original Research

Published on 19 Aug 2025

Association between the depression and cardiovascular risk in arthritis patients: a prospective cohort study from the CHARLS database

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Xiaoyuan Tian
Xianglin Yang
Ying Cao
Zhenan Qu
Bocheng Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590483

6,116 views
1 citation

Case Report

Published on 18 Aug 2025

Case Report: Dual immunomodulatory and hematologic benefits of rituximab in refractory anemia of ANCA-associated vasculitis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Ningjun Shao
Lingxiong Chai
Xu Bai
Qun Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600250

2,912 views

Original Research

Published on 18 Aug 2025

Dual vs. isolated anti-Ro antibody positivity in rheumatoid arthritis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yan Ma
Chaoyu Gu
Qianqian Li
Liangjing Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661334

3,623 views

Case Report

Published on 18 Aug 2025

Case Report: Prenatal diagnosis of gastrointestinal defects and immunodeficiency syndrome caused by compound heterozygous mutations in TTC7A gene

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Shuning Han
Miaomiao Wang
Pengzhen Jin
Jiawei Hong
Chunfei Xu
Minyue Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611155

1,895 views

546 articles

articles

The diverse N-glycosylation profiles of CD4+CD25- and CD4+CD25+ T cells in Hashimoto’s thyroiditis

STING-targeting PROTACs: emerging therapeutic tools for enhanced immunotherapy in inflammatory diseases

Decoding the inflammatory-osteogenic axis in ankylosing spondylitis: mechanisms, dysregulation, and emerging therapeutic interventions

A splicing-based multitissue association study of joint transcriptomes identified susceptibility genes for osteoarthritis

Cutaneous mucormycosis in systemic lupus erythematosus: a case report

Association of FCGR2A rs1801274 and FCGR3A rs396991 polymorphisms with various autoimmune diseases: a meta-analysis

Cytotoxic T lymphocyte-associated protein 4 gene polymorphisms are associated with ANCA-associated vasculitis in the Guangxi population of China

Severe fatigue is associated with diminished lung function and elevated Galectin-9 levels in early systemic sclerosis

Novel USP18 mutations lead to severe interferonopathy responsive to JAK inhibitor

Overlapping features of atopic dermatitis and alopecia areata: from pathogenesis to treatment

Case Report: Acute onset hemiparesis in a young man: do not miss Crohn’s disease

Assessment of gene signatures following the inhibition of IL-23: a study to evaluate the mechanistic effects behind the clinical efficacy of guselkumab in patients with psoriatic arthritis

Exploring the interplay of prolactin and bromocriptine on serum markers in granulomatous lobular mastitis

Hypocomplementemia dynamics during tocilizumab therapy in systemic juvenile idiopathic arthritis: a retrospective longitudinal study

The utilization of efgartigimod in the treatment of acute cerebellar ataxia: a case report

Pediatric inflammatory bowel disease and cancer

Misfortunes never come alone: melanoma and ulcerative colitis after biologic therapy in a psoriatic patient – a case report and literature review

Adult onset cryopyrin-associated periodic syndrome due to germline missense mutation in NLRP3 in a previously healthy middle-aged woman

Novel advances on pathophysiological mechanisms, clinical manifestations, and treatment of antiphospholipid syndrome

Antibodies against integrin αvβ6 have high diagnostic accuracy for ulcerative colitis

Association between the depression and cardiovascular risk in arthritis patients: a prospective cohort study from the CHARLS database

Case Report: Dual immunomodulatory and hematologic benefits of rituximab in refractory anemia of ANCA-associated vasculitis

Dual vs. isolated anti-Ro antibody positivity in rheumatoid arthritis

Case Report: Prenatal diagnosis of gastrointestinal defects and immunodeficiency syndrome caused by compound heterozygous mutations in TTC7A gene