Frontiers in Immunology | B Cell Biology

Original Research

Published on 11 Nov 2025

Mitogen-activated protein kinase pathway and four genes involved in the development of benign prostatic hyperplasia: in vivo and vitro validation

in B Cell Biology

Jia-Min Gu
Xing-Pei Guo
Lan Wu
Lu-Yao Li
Cong Zhu
Tong Deng
Shuang-Ying Wang
Cheng Fang
Xian-Tao Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606607

540 views

Brief Research Report

Published on 06 Nov 2025

Biochemical analysis reveals aberrant and variable Immunoglobulin M composition in Waldenström macroglobulinemia and IgM monoclonal gammopathy of unknown significance

in B Cell Biology

Nienke Oskam
Wouter Verhaar
Pleuni Ooijevaar-de Heer
Karima Amaador
Ninotska I. L. Derksen
Sofie Keijzer
Marie José Kersten
Marij Streutker
Josephine M. I. Vos
Theo Rispens

Frontiers in Immunology

doi 10.3389/fimmu.2025.1670408

826 views

Review

Accepted on 05 Nov 2025

Temporal dynamics of IgG-mediated immunometabolic dysfunction: From acute obesity to chronic aging

in B Cell Biology

Sohyun Kim
Junghyun Kim
Man S Kim

Frontiers in Immunology

310 views

Original Research

Published on 05 Nov 2025

The tropomyosin 3.1/3.2 inhibitor ATM-3507 alters B-cell actin dynamics and impairs the growth and motility of diffuse large B-cell lymphoma cell lines

in B Cell Biology

Abhishek Bedi
Kate Choi
Alyssa Iskierski
Michael R. Gold

Frontiers in Immunology

doi 10.3389/fimmu.2025.1668379

832 views

Original Research

Accepted on 03 Nov 2025

Human Interleukin-4-Dependent Facilitation of Human IgG Production in PBL-NOG-hIL-4-Tg mice

in B Cell Biology

Yoshie Kametani
Shino Oshima
Ryoji Ito
Yusuke Ohno
Soga Yamada
Yuki Hoshino
Asuka Miyamoto
Mao Suzuki
Nagi Katano
Banri Tsuda

Frontiers in Immunology

Hypothesis and Theory

Accepted on 03 Nov 2025

On the carrying capacity of the bone marrow survival niche in mice

in B Cell Biology

Keisuke Tonouchi
Chen-Hao Yeh
Derek Cain
E. Ashley Moseman
Barton Haynes
Kshitij Wagh
Kevin Wiehe
Tomohiro Kurosaki
Garnett Kelsoe

Frontiers in Immunology

Original Research

Published on 31 Oct 2025

B cell receptor repertoire reconstitution in patients with neuromyelitis optica spectrum disorder receiving B-cell depletion therapy

in B Cell Biology

Hyo Jae Kim
Wangyong Shin
Dayoung Seo
Inhye Jang
Jihong Ryu
Lynkyung Choi
Jinhee Kim
Hyunjin Kim
Young-Min Lim
Eun-Jae Lee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673508

1,253 views

Mini Review

Published on 30 Oct 2025

The dual immunomodulatory role of B cells in tumorigenesis: mechanisms, microenvironment crosstalk, and therapeutic implications

in B Cell Biology

Zhuangwei Lv
Ruohao Yang
Kai Zhang
Ruihan Wang
Xiaoyu Shi
Jinhua Wu
LuLu Liu
Junna Jiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649812

697 views

Original Research

Accepted on 27 Oct 2025

Splenectomy modulates intrarenal B cell differentiation and impairs repair of post-ischemic kidney

in B Cell Biology

Kyungho Lee
Hojin Jeon
Kyung Sub Lee
Junseok Jeon
Jung Eun Lee
Ghee Young Kwon
Wooseong Huh
Hye Ryoun Jang

Frontiers in Immunology

134 views

Hypothesis and Theory

Accepted on 21 Oct 2025

Exuberant long noncoding RNA expression may sculpt Igh locus topology

in B Cell Biology

Ellen Brandenburg Drake
Sarah Naiyer
Xinyan Qu
Khalid Bhat
Hammad Farooq
Mark Maienschein-Cline
Jie Liang
Amy L Kenter

Frontiers in Immunology

195 views

Original Research

Published on 20 Oct 2025

CD39 is an antibody-secreting B-cell marker that modulates germinal center and antibody responses during infection

in B Cell Biology

Laura Almada
Yamila N. Gazzoni
Cristian G. Beccaria
Facundo Fiocca Vernengo
Santiago Boccardo
Melisa Gorosito Serrán
Apurwa Trivedi
Carola G. Vinuesa
Simon C. Robson
Eva V. Acosta Rodríguez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547929

1,749 views

Original Research

Published on 17 Oct 2025

Pediatric B cell repertoires are enriched for naive clonal phenotypes and are shaped by distinct selection dynamics

in B Cell Biology

Thomas Hsiao
Areen Shtewe
Uri Hershberg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618234

1,842 views

Original Research

Published on 16 Oct 2025

B cell subpopulations and their role in the pathogenesis of primary Sjögren’s syndrome: insights from single-cell RNA sequencing

in B Cell Biology

Xiaoyu Zhang
Yuanwei Han
Jing Zhang
Yu Song
Yan Zhou
Jia Wang
Jinhai Tian
Xinran Xin
Bin Liu
Li Fang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665086

2,542 views

Original Research

Published on 15 Oct 2025

Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis

in B Cell Biology

Xuan Wu
Wei Chen
Huanhuan Song
Guorong Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667799

2,248 views

Original Research

Published on 14 Oct 2025

Agglutinin chip screening of B cell surface biomarkers in Hashimoto’s thyroiditis for therapeutic targeting

in B Cell Biology

Jun-ling Ren
Xiao-ming Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636003

2,272 views

Original Research

Published on 13 Oct 2025

Directed evolution of drug-like Aβ conformation-specific antibodies

in B Cell Biology

Alec A. Desai
Matthew D. Smith
Jennifer M. Zupancic
Emily K. Makowski
Yulei Zhang
Julia E. Gerson
Shannon J. Moore
Alexandra B. Sutter
Sean P. Ferris
Magdalena I. Ivanova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655893

1,533 views