Frontiers in Immunology | B Cell Biology

Mini Review

Published on 22 Jan 2018

Bruton’s Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus

in B Cell Biology

Anne B. Satterthwaite

Frontiers in Immunology

doi 10.3389/fimmu.2017.01986

12,087 views
41 citations

Original Research

Published on 19 Jan 2018

Expression of Tumor Necrosis Factor Receptor 2 Characterizes TLR9-Driven Formation of Interleukin-10-Producing B Cells

in B Cell Biology

Olga Ticha
Lukas Moos
Harald Wajant
Isabelle Bekeredjian-Ding

Frontiers in Immunology

doi 10.3389/fimmu.2017.01951

9,803 views
48 citations

Original Research

Published on 19 Jan 2018

Immune Tolerance to Apoptotic Self Is Mediated Primarily by Regulatory B1a Cells

in B Cell Biology

Katherine Miles
Joanne Simpson
Sheila Brown
Graeme Cowan
David Gray
Mohini Gray

Frontiers in Immunology

doi 10.3389/fimmu.2017.01952

7,885 views
28 citations

Original Research

Published on 10 Jan 2018

B Cell-Intrinsic Role for IRF5 in TLR9/BCR-Induced Human B Cell Activation, Proliferation, and Plasmablast Differentiation

in B Cell Biology

Saurav De
Baohong Zhang
Tiffany Shih
Sukhwinder Singh
Aaron Winkler
Robert Donnelly
Betsy J. Barnes

Frontiers in Immunology

doi 10.3389/fimmu.2017.01938

16,414 views
56 citations

Original Research

Published on 09 Jan 2018

Genomic Region Containing Toll-Like Receptor Genes Has a Major Impact on Total IgM Antibodies Including KLH-Binding IgM Natural Antibodies in Chickens

in B Cell Biology

Tom V. L. Berghof
Marleen H. P. W. Visker
Joop A. J. Arts
Henk K. Parmentier
Jan J. van der Poel
Addie L. J. Vereijken
Henk Bovenhuis

Frontiers in Immunology

doi 10.3389/fimmu.2017.01879

7,979 views
30 citations

Original Research

Published on 22 Dec 2017

Functionally Convergent B Cell Receptor Sequences in Transgenic Rats Expressing a Human B Cell Repertoire in Response to Tetanus Toxoid and Measles Antigens

in B Cell Biology

Jean-Philippe Bürckert
Axel R. S. X. Dubois
William J. Faison
Sophie Farinelle
Emilie Charpentier
Regina Sinner
Anke Wienecke-Baldacchino
Claude P. Muller

Frontiers in Immunology

doi 10.3389/fimmu.2017.01834

8,609 views
19 citations

Methods

Published on 20 Dec 2017

Pacific Biosciences Sequencing and IMGT/HighV-QUEST Analysis of Full-Length Single Chain Fragment Variable from an In Vivo Selected Phage-Display Combinatorial Library

in B Cell Biology

Audrey Hemadou
Véronique Giudicelli
Melissa Laird Smith
Marie-Paule Lefranc
Patrice Duroux
Sofia Kossida
Cheryl Heiner
N. Lance Hepler
John Kuijpers
Alexis Groppi

Frontiers in Immunology

doi 10.3389/fimmu.2017.01796

10,397 views
28 citations

Original Research

Published on 19 Dec 2017

Co-Stimulation of BCR and Toll-Like Receptor 7 Increases Somatic Hypermutation, Memory B Cell Formation, and Secondary Antibody Response to Protein Antigen

in B Cell Biology

Diana P. Castiblanco
Robert W. Maul
Lisa M. Russell Knode
Patricia J. Gearhart

Frontiers in Immunology

doi 10.3389/fimmu.2017.01833

10,091 views
24 citations

Editorial

Published on 13 Dec 2017

Editorial: Natural Antibodies in Health and Disease

in B Cell Biology

Ana Maria Hernandez
Nichol E. Holodick

Frontiers in Immunology

doi 10.3389/fimmu.2017.01795

11,427 views
12 citations

Original Research

Published on 11 Dec 2017

Myosin 1g Contributes to CD44 Adhesion Protein and Lipid Rafts Recycling and Controls CD44 Capping and Cell Migration in B Lymphocytes

in B Cell Biology

Orestes López-Ortega
Leopoldo Santos-Argumedo

Frontiers in Immunology

doi 10.3389/fimmu.2017.01731

6,784 views
26 citations

Review

Published on 08 Dec 2017

How B-Cell Receptor Repertoire Sequencing Can Be Enriched with Structural Antibody Data

in B Cell Biology

Aleksandr Kovaltsuk
Konrad Krawczyk
Jacob D. Galson
Dominic F. Kelly
Charlotte M. Deane
Johannes Trück

Frontiers in Immunology

doi 10.3389/fimmu.2017.01753

34,788 views
61 citations

Original Research

Published on 06 Dec 2017

Circulating Plasmablasts from Chronically Human Immunodeficiency Virus-Infected Individuals Predominantly Produce Polyreactive/Autoreactive Antibodies

in B Cell Biology

Hongyan Liao
Yangsheng Yu
Song Li
Yinshi Yue
Chuanmin Tao
Kaihong Su
Zhixin Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2017.01691

4,324 views
9 citations

Perspective

Published on 23 Nov 2017

Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory

in B Cell Biology

Edward J. Steele

Frontiers in Immunology

doi 10.3389/fimmu.2017.01611

5,544 views
12 citations

Original Research

Published on 17 Nov 2017

Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination

in B Cell Biology

Louise S. Matheson
Daniel J. Bolland
Peter Chovanec
Felix Krueger
Simon Andrews
Hashem Koohy
Anne E. Corcoran

Frontiers in Immunology

doi 10.3389/fimmu.2017.01550

8,247 views
30 citations

Review

Published on 13 Nov 2017

B Cell Intrinsic Mechanisms Constraining IgE Memory

in B Cell Biology

Brice Laffleur
Orianne Debeaupuis
Zeinab Dalloul
Michel Cogné

Frontiers in Immunology

doi 10.3389/fimmu.2017.01277

10,840 views
17 citations

Original Research

Published on 13 Nov 2017

Antibody Heavy Chain Variable Domains of Different Germline Gene Origins Diversify through Different Paths

in B Cell Biology

Ufuk Kirik
Helena Persson
Fredrik Levander
Lennart Greiff
Mats Ohlin

Frontiers in Immunology

doi 10.3389/fimmu.2017.01433

26,701 views
40 citations

Perspective

Published on 01 Nov 2017

Reproducibility and Reuse of Adaptive Immune Receptor Repertoire Data

in B Cell Biology

Felix Breden
Eline T. Luning Prak
Bjoern Peters
Florian Rubelt
Chaim A. Schramm
Christian E. Busse
Jason A. Vander Heiden
Scott Christley
Syed Ahmad Chan Bukhari
Adrian Thorogood

Frontiers in Immunology

doi 10.3389/fimmu.2017.01418

17,519 views
101 citations

Original Research

Published on 24 Oct 2017

A Role for the Transcription Factor Arid3a in Mouse B2 Lymphocyte Expansion and Peritoneal B1a Generation

in B Cell Biology

Katrin Habir
Shahin Aeinehband
Fredrik Wermeling
Stephen Malin

Frontiers in Immunology

doi 10.3389/fimmu.2017.01387

5,093 views
12 citations

Original Research

Published on 16 Oct 2017

Immune Repertoire after Immunization As Seen by Next-Generation Sequencing and Proteomics

in B Cell Biology

Martijn M. VanDuijn
Lennard J. Dekker
Wilfred F. J. van IJcken
Peter A. E. Sillevis Smitt
Theo M. Luider

Frontiers in Immunology

doi 10.3389/fimmu.2017.01286

10,167 views
21 citations

Original Research

Published on 06 Oct 2017

The Small Rho GTPases Rac1 and Rac2 Are Important for T-Cell Independent Antigen Responses and for Suppressing Switching to IgG2b in Mice

in B Cell Biology

Natalija Gerasimčik
Minghui He
Carin I. M. Dahlberg
Nikolai V. Kuznetsov
Eva Severinson
Lisa S. Westerberg

Frontiers in Immunology

doi 10.3389/fimmu.2017.01264

6,763 views
23 citations

Methods

Published on 14 Sep 2017

Novel Method for High-Throughput Full-Length IGHV-D-J Sequencing of the Immune Repertoire from Bulk B-Cells with Single-Cell Resolution

in B Cell Biology

Stefano Vergani
Ilya Korsunsky
Andrea Nicola Mazzarello
Gerardo Ferrer
Nicholas Chiorazzi
Davide Bagnara

Frontiers in Immunology

doi 10.3389/fimmu.2017.01157

13,894 views
43 citations

Original Research

Published on 13 Sep 2017

Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes

in B Cell Biology

Gabrielle McDonald
Carlos O. Medina
Monika Pilichowska
John F. Kearney
Reiko Shinkura
Erik Selsing
Henry H. Wortis
Tasuku Honjo
Thereza Imanishi-Kari

Frontiers in Immunology

doi 10.3389/fimmu.2017.01094

7,159 views
17 citations

Methods

Published on 04 Sep 2017

A Streamlined Approach to Antibody Novel Germline Allele Prediction and Validation

in B Cell Biology

Ben S. Wendel
Chenfeng He
Peter D. Crompton
Susan K. Pierce
Ning Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2017.01072

5,827 views
8 citations

Original Research

Published on 04 Sep 2017

CCCTC-Binding Factor Locks Premature IgH Germline Transcription and Restrains Class Switch Recombination

in B Cell Biology

Ester Marina-Zárate
Arantxa Pérez-García
Almudena R. Ramiro

Frontiers in Immunology

doi 10.3389/fimmu.2017.01076

4,513 views
10 citations

1,037 articles

articles

Bruton’s Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus

Expression of Tumor Necrosis Factor Receptor 2 Characterizes TLR9-Driven Formation of Interleukin-10-Producing B Cells

Immune Tolerance to Apoptotic Self Is Mediated Primarily by Regulatory B1a Cells

B Cell-Intrinsic Role for IRF5 in TLR9/BCR-Induced Human B Cell Activation, Proliferation, and Plasmablast Differentiation

Genomic Region Containing Toll-Like Receptor Genes Has a Major Impact on Total IgM Antibodies Including KLH-Binding IgM Natural Antibodies in Chickens

Functionally Convergent B Cell Receptor Sequences in Transgenic Rats Expressing a Human B Cell Repertoire in Response to Tetanus Toxoid and Measles Antigens

Pacific Biosciences Sequencing and IMGT/HighV-QUEST Analysis of Full-Length Single Chain Fragment Variable from an In Vivo Selected Phage-Display Combinatorial Library

Co-Stimulation of BCR and Toll-Like Receptor 7 Increases Somatic Hypermutation, Memory B Cell Formation, and Secondary Antibody Response to Protein Antigen

Editorial: Natural Antibodies in Health and Disease

Myosin 1g Contributes to CD44 Adhesion Protein and Lipid Rafts Recycling and Controls CD44 Capping and Cell Migration in B Lymphocytes

How B-Cell Receptor Repertoire Sequencing Can Be Enriched with Structural Antibody Data

Circulating Plasmablasts from Chronically Human Immunodeficiency Virus-Infected Individuals Predominantly Produce Polyreactive/Autoreactive Antibodies

Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory

Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination

B Cell Intrinsic Mechanisms Constraining IgE Memory

Antibody Heavy Chain Variable Domains of Different Germline Gene Origins Diversify through Different Paths

Reproducibility and Reuse of Adaptive Immune Receptor Repertoire Data

A Role for the Transcription Factor Arid3a in Mouse B2 Lymphocyte Expansion and Peritoneal B1a Generation

Immune Repertoire after Immunization As Seen by Next-Generation Sequencing and Proteomics

The Small Rho GTPases Rac1 and Rac2 Are Important for T-Cell Independent Antigen Responses and for Suppressing Switching to IgG2b in Mice

Novel Method for High-Throughput Full-Length IGHV-D-J Sequencing of the Immune Repertoire from Bulk B-Cells with Single-Cell Resolution

Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes

A Streamlined Approach to Antibody Novel Germline Allele Prediction and Validation

CCCTC-Binding Factor Locks Premature IgH Germline Transcription and Restrains Class Switch Recombination