Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Published on 10 Feb 2025

CD32B1, a versatile non-signaling antibody-binding scaffold for enhanced T cell adhesion to tumor stromal cognate antigens

in Cancer Immunity and Immunotherapy

Sara W. Feigelson
Tali Dadosh
Nehora Levi
Anita Sapoznikov
Hadas Weinstein-Marom
Dayana Blokon-Kogan
Yahel Avraham
Tamar Unger
Gideon Gross
Rony Dahan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1398757

344 views

Original Research

Published on 10 Feb 2025

Developing transcriptomic biomarkers for TAVO412 utilizing next generation sequencing analyses of preclinical tumor models

in Cancer Immunity and Immunotherapy

Ying Jin
Peng Chen
Huajun Zhou
Guangmao Mu
Simin Wu
Zhengxia Zha
Bin Ma
Chao Han
Mark L. Chiu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1505868

370 views

Perspective

Published on 10 Feb 2025

Six events that shaped antibody approvals in oncology

in Cancer Immunity and Immunotherapy

Suman Paul
Shibin Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1533796

495 views

Review

Published on 10 Feb 2025

Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy

in Cancer Immunity and Immunotherapy

Anna De Lucia
Lucia Mazzotti
Anna Gaimari
Matteo Zurlo
Roberta Maltoni
Claudio Cerchione
Sara Bravaccini
Angelo Delmonte
Lucio Crinò
Patricia Borges de Souza

Frontiers in Immunology

doi 10.3389/fimmu.2025.1515748

500 views

Original Research

Published on 10 Feb 2025

A prognostic signature of Glutathione metabolism-associated long non-coding RNAs for lung adenocarcinoma with immune microenvironment insights

in Cancer Immunity and Immunotherapy

Junxi Hu
Shuyu Tian
Qingwen Liu
Jiaqi Hou
Jun wu
Xiaolin Wang
Yusheng Shu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1477437

232 views

Case Report

Published on 10 Feb 2025

Case report: A severe myositis mimicking bulbar palsy after administration of immune checkpoint inhibitors

in Cancer Immunity and Immunotherapy

Philippe Rochigneux
Alexandre Bertucci
Elika Loir
Alexia Mattei
Danielle Robert
Michael Dassa
Brice Chanez
Mikael Ebbo
Lea Gaigne
Anne Sophie Chretien

Frontiers in Immunology

doi 10.3389/fimmu.2025.1496427

291 views

Review

Accepted on 07 Feb 2025

Advances in primary large B-cell lymphoma of immune-privileged sites

in Cancer Immunity and Immunotherapy

Liao Wang
Meiru Guo
Shuling Hou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1533444

Clinical Trial

Accepted on 07 Feb 2025

Phase 2 study of chidamide in combination with CAG and venetoclax-azacitidine in older patients with newly diagnosed acute myeloid leukemia

in Cancer Immunity and Immunotherapy

Qingyang Liu
Jingjing Yang
Lei Lv
Xiawei Zhang
Meng Li
Lingmin Xu
Sai Huang
Yu Jing
Liping Dou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1525110

Original Research

Accepted on 07 Feb 2025

Oropharyngeal carcinomas induce circulating monocytes to express a TAM-like pro-tumor expression profile that suppresses T-cell proliferation

in Cancer Immunity and Immunotherapy

Christopher Papayannakos
Mohd Israr
James Allan Devoti
Fung Lam
Arnon Arazi
Douglas K. Frank
Dev Kamdar
Lucio M. Pereira
Nagashree Seetharamu
Bettie M Steinberg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539780

Original Research

Published on 07 Feb 2025

GNA15 predicts poor outcomes as a novel biomarker related to M2 macrophage infiltration in ovarian cancer

in Cancer Immunity and Immunotherapy

Qin Liu
Yabing Sun
Tao Zhang
Wanrun Lin
Jing Zhang
Huijuan Zhang
Wenxin Zheng
Hong Xu
Feng Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1512086

484 views

Review

Published on 07 Feb 2025

Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics

in Cancer Immunity and Immunotherapy

BingBing Li
Cheng Zhang
XiaoJuan Xu
QiQin Shen
ShuNan Luo
JunFeng Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539396

363 views

Original Research

Published on 07 Feb 2025

NOX4 modulates breast cancer progression through cancer cell metabolic reprogramming and CD8+ T cell antitumor activity

in Cancer Immunity and Immunotherapy

Yingying Xiong
Yiming Weng
Shan Zhu
Jian Qin
Jia Feng
Xiaopeng Jing
Chao Luo
Wei Gong
Rui Sun
Min Peng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534936

592 views

Original Research

Published on 07 Feb 2025

Multi-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer

in Cancer Immunity and Immunotherapy

Rui Wu
Kunchen Wei
Xingshuai Huang
Yinge Zhou
Xiao Feng
Xin Dong
Hao Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1479550

350 views

Original Research

Accepted on 06 Feb 2025

Bioinformatics analysis reveals novel tumor antigens and immune subtypes of skin cutaneous melanoma contributing to mRNA vaccine development

in Cancer Immunity and Immunotherapy

Ronghua Yang
He Jia
Deni Kang
Yao Chen
Jie Huang
Jiehua Li
Xinyi Wang
Sitong Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1520505

123 views

Review

Accepted on 06 Feb 2025

Research progress of T cells in cholangiocarcinoma

in Cancer Immunity and Immunotherapy

Zhiming Wang
Yunyan Dai
Yunpeng Zhou
Yi Wang
Pinggui Chen
Yaoxuan Li
Yunfei Zhang
Xiaocui Wang
Ying Hu
Haonan Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1453344

Case Report

Accepted on 06 Feb 2025

Severe Thyroiditis Induced by Sintilimab monotherapy in a Patient with Non-Small Cell Lung Cancer: A Case Report and literature review

in Cancer Immunity and Immunotherapy

Xiaolin Zhao
Xiaoyu Wang
Surui Liu
Pian Cheng
Jinjuan Chen
Jie Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1548452

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Articles

CD32B1, a versatile non-signaling antibody-binding scaffold for enhanced T cell adhesion to tumor stromal cognate antigens

Developing transcriptomic biomarkers for TAVO412 utilizing next generation sequencing analyses of preclinical tumor models

Six events that shaped antibody approvals in oncology

Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy

A prognostic signature of Glutathione metabolism-associated long non-coding RNAs for lung adenocarcinoma with immune microenvironment insights

Case report: A severe myositis mimicking bulbar palsy after administration of immune checkpoint inhibitors

Advances in primary large B-cell lymphoma of immune-privileged sites

Phase 2 study of chidamide in combination with CAG and venetoclax-azacitidine in older patients with newly diagnosed acute myeloid leukemia

Oropharyngeal carcinomas induce circulating monocytes to express a TAM-like pro-tumor expression profile that suppresses T-cell proliferation

GNA15 predicts poor outcomes as a novel biomarker related to M2 macrophage infiltration in ovarian cancer

Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics

NOX4 modulates breast cancer progression through cancer cell metabolic reprogramming and CD8+ T cell antitumor activity

Multi-omics analysis reveals the sensitivity of immunotherapy for unresectable non-small cell lung cancer

Bioinformatics analysis reveals novel tumor antigens and immune subtypes of skin cutaneous melanoma contributing to mRNA vaccine development

Research progress of T cells in cholangiocarcinoma

Severe Thyroiditis Induced by Sintilimab monotherapy in a Patient with Non-Small Cell Lung Cancer: A Case Report and literature review