Frontiers in Immunology | Cancer Immunity and Immunotherapy

Systematic Review

Published on 06 Feb 2025

Efficacy and safety of first-line PD-1/PD-L1 inhibitor in combination with CTLA-4 inhibitor in the treatment of patients with advanced non-small cell lung cancer: a systemic review and meta-analysis

in Cancer Immunity and Immunotherapy

Huimin Zhao
Shanshan Huang
Jianyu Wu
Yanlan Lu
Yue Zou
Haijian Zeng
Chunlan Li
Jin Wang
Xiaochen Zhang
Siliang Duan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1515027

577 views

Hypothesis and Theory

Published on 06 Feb 2025

Microbes, macrophages, and melanin: a unifying theory of disease as exemplified by cancer

in Cancer Immunity and Immunotherapy

Stacie Z. Berg
Jonathan Berg

Frontiers in Immunology

doi 10.3389/fimmu.2024.1493978

755 views

Review

Published on 06 Feb 2025

Cancer stem cells and tumor-associated macrophages as mates in tumor progression: mechanisms of crosstalk and advanced bioinformatic tools to dissect their phenotypes and interaction

in Cancer Immunity and Immunotherapy

Francesco Verona
Sebastiano Di Bella
Roberto Schirano
Camilla Manfredi
Francesca Angeloro
Giulia Bozzari
Matilde Todaro
Giuseppe Giannini
Giorgio Stassi
Veronica Veschi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1529847

1,034 views

Review

Published on 06 Feb 2025

Research progress of HIF-1a on immunotherapy outcomes in immune vascular microenvironment

in Cancer Immunity and Immunotherapy

Shaoyan Shi
Xuehai Ou
Chao Liu
Hao Wen
Jiang Ke

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549276

475 views

Original Research

Accepted on 05 Feb 2025

Expression of SIRPα-Fc by Oncolytic Virus Enhances Antitumor Efficacy through Tumor Microenvironment Reprogramming

in Cancer Immunity and Immunotherapy

Qingzhe Yang
Yongheng Shu
Yanwei Chen
Zhongbing Qi
Shichuan Hu
Yao Zhang
Yu Qin
Xianglin Xu
Jianchuan Hu
Anliang Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513555

106 views

Review

Accepted on 05 Feb 2025

Analysis of single-cell and spatial transcriptomics in TNBC cell-cell interactions

in Cancer Immunity and Immunotherapy

Yan Xin
Qiji Ma
Qiang Deng
Tielin Wang
Dongxu Wang
Gang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1521388

Original Research

Accepted on 05 Feb 2025

The C/EBPβ antagonist peptide Lucicebtide (ST101) induces macrophage polarization toward a pro-inflammatory phenotype and enhances anti-tumor immune responses

in Cancer Immunity and Immunotherapy

Claudio Scuoppo
Ricardo Ramirez
Siok Leong
Mark Koester
Zachary Mattes
Karen Mendelson
Julia Diehl
Franco Abbate
Erin Gallagher
Lila Ghamsari

Frontiers in Immunology

doi 10.3389/fimmu.2025.1522699

125 views

Original Research

Accepted on 05 Feb 2025

Maplirpacept: A CD47 Decoy Receptor with Minimal Red Blood Cell Binding and Robust Anti-Tumor Efficacy

in Cancer Immunity and Immunotherapy

Mithunah Krishnamoorthy
Ruth Seelige
Christopher R Brown
Nancy Chau
Natasja Nielsen Viller
Lisa Johnson
Emma Linderoth
Jean C Y Wang
Christopher Dillon
Keith Abayasiriwardana

Frontiers in Immunology

doi 10.3389/fimmu.2025.1518787

110 views

Review

Accepted on 05 Feb 2025

The Potential Applications of Peptide-Loading Complex in Cancer Treatment

in Cancer Immunity and Immunotherapy

Zhidu Song
Ying Tao
Jiaxin You

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526137

Mini Review

Published on 05 Feb 2025

Advancements in cellular immunotherapy: overcoming resistance in lung and colorectal cancer

in Cancer Immunity and Immunotherapy

Lijuan Qin
Yuan Li
Juan Liu
Xiaoqin An

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554256

899 views

Review

Published on 05 Feb 2025

Epigenetic modifications in bladder cancer: crosstalk between DNA methylation and miRNAs

in Cancer Immunity and Immunotherapy

Wei Li
Peiyue Luo
Qi Chen
Le Cheng
Lifeng Gan
Fangtao Zhang
Haidong Zhong
Liying Zheng
Biao Qian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1518144

272 views

Original Research

Published on 05 Feb 2025

Single-cell sequencing elucidates the mechanism of NUSAP1 in glioma and its diagnostic and prognostic significance

in Cancer Immunity and Immunotherapy

Meng-Yu Zhao
Zhao-Lei Shen
Hongzhen Dai
Wan-Yan Xu
Li-Na Wang
Yu- Gu
Jie-Hui Zhao
Tian-Hang Yu
Cun-Zhi Wang
Jia-feng Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1512867

448 views

Original Research

Published on 05 Feb 2025

IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3

in Cancer Immunity and Immunotherapy

Huiyue Dong
Ling Zhu
Jingjing Sun
Qiuyan Chen
Pengyang Liu
Wei Zhang
Huajing Zeng
Rong Lin
Zongyang Yu
Jun Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535554

507 views

Case Report

Published on 05 Feb 2025

Dynamics of blood microsatellite instability (bMSI) burden predicts outcome of a patient treated with immune checkpoint inhibitors: a case report of hyperprogressive disease

in Cancer Immunity and Immunotherapy

Daria Kravchuk
Alexandra Lebedeva
Olesya Kuznetsova
Alexandra Kavun
Anastasiia Taraskina
Ekaterina Belova
Tatiana Grigoreva
Egor Veselovsky
Vladislav Mileyko
Vladislav Nikulin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1492296

260 views

Original Research

Published on 05 Feb 2025

Bioinformatic characterization of STING expression in hematological malignancies reveals association with prognosis and anti-tumor immunity

in Cancer Immunity and Immunotherapy

Xiang-mei Wen
Zi-jun Xu
Ji-chun Ma
Min-jie Zhang
Ye Jin
Jiang Lin
Jun Qian
Yuan-yuan Fang
Shu-yu Luo
Zhen-wei Mao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1477100

478 views

Original Research

Published on 05 Feb 2025

Polymorphisms in immunosuppression-related genes are associated with AML

in Cancer Immunity and Immunotherapy

Mingying Li
Jingjing Ye
Mengyuan Chang
Lei Feng
Tingting Liu
Di Zhang
Yuyan Wu
Yuechan Ma
Guangqiang Meng
Chunyan Ji

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530510

378 views

Navigation group

Articles

Efficacy and safety of first-line PD-1/PD-L1 inhibitor in combination with CTLA-4 inhibitor in the treatment of patients with advanced non-small cell lung cancer: a systemic review and meta-analysis

Microbes, macrophages, and melanin: a unifying theory of disease as exemplified by cancer

Cancer stem cells and tumor-associated macrophages as mates in tumor progression: mechanisms of crosstalk and advanced bioinformatic tools to dissect their phenotypes and interaction

Research progress of HIF-1a on immunotherapy outcomes in immune vascular microenvironment

Expression of SIRPα-Fc by Oncolytic Virus Enhances Antitumor Efficacy through Tumor Microenvironment Reprogramming

Analysis of single-cell and spatial transcriptomics in TNBC cell-cell interactions

The C/EBPβ antagonist peptide Lucicebtide (ST101) induces macrophage polarization toward a pro-inflammatory phenotype and enhances anti-tumor immune responses

Maplirpacept: A CD47 Decoy Receptor with Minimal Red Blood Cell Binding and Robust Anti-Tumor Efficacy

The Potential Applications of Peptide-Loading Complex in Cancer Treatment

Advancements in cellular immunotherapy: overcoming resistance in lung and colorectal cancer

Epigenetic modifications in bladder cancer: crosstalk between DNA methylation and miRNAs

Single-cell sequencing elucidates the mechanism of NUSAP1 in glioma and its diagnostic and prognostic significance

IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3

Dynamics of blood microsatellite instability (bMSI) burden predicts outcome of a patient treated with immune checkpoint inhibitors: a case report of hyperprogressive disease

Bioinformatic characterization of STING expression in hematological malignancies reveals association with prognosis and anti-tumor immunity

Polymorphisms in immunosuppression-related genes are associated with AML