Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Accepted on 17 Feb 2025

Targeting stemness pathways modulates macrophage polarization and reprograms the tumor microenvironment

in Cancer Immunity and Immunotherapy

Austėja Butkutė
Marius Baltramonaitis
Simona Malmige
Adas Darinskas
Vita Pasukoniene
Agata Mlynska

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513404

Case Report

Accepted on 17 Feb 2025

Case Report: Severe Pneumocystis jirovecii Pneumonia Following Zuberitamab Treatment in Autoimmune Hemolytic Anemia

in Cancer Immunity and Immunotherapy

Qian Yang
Peng Ding
Yuxiang Liu
Kaichen Zhang
Peiyang Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1546571

Mini Review

Accepted on 17 Feb 2025

PARylation-Mediated Post-Transcriptional Modifications in Cancer Immunity and Immunotherapy

in Cancer Immunity and Immunotherapy

Kazuya Matsumoto
Yoshinori Matsumoto
Jun Wada

Frontiers in Immunology

doi 10.3389/fimmu.2025.1537615

Original Research

Accepted on 17 Feb 2025

Exploring NUP62's Role in Cancer Progression, Tumor Immunity, and Treatment Response: Insights from Multiomics Analysis

in Cancer Immunity and Immunotherapy

Lihong Chen
Youfu He
Menghui Duan
Tianwen Yang
Yin Chen
Bo Wang
Dejun Cui
Chen Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1559396

Review

Accepted on 17 Feb 2025

The role of intestinal macrophage polarization in colitis-associated colon cancer

in Cancer Immunity and Immunotherapy

Yujie Deng
Xiaobing Jia
Liu Liu
Qiao He
Lei Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1537631

Original Research

Accepted on 17 Feb 2025

Immune Checkpoint Inhibitors and Cancer-Related Cognitive Decline: A Propensity Score Matched Analysis in active Chemotherapy Patients

in Cancer Immunity and Immunotherapy

Guangmin Jian
Jiling Zeng
Jun Lu
Weidong Wang
Yongluo Jiang
Tong Huang
Yu Si Niu
Zhoufang Chai
Xin Qi
Nianqi Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1540442

Original Research

Accepted on 17 Feb 2025

Metabolic Reprogramming Shapes the Immune Microenvironment in Pancreatic Adenocarcinoma: Prognostic Implications and Therapeutic Targets

in Cancer Immunity and Immunotherapy

Weihua Song
Yabin Yu
Siqi Wang
Zhengyi Cui
Qiusi Zhu
Wangrui Liu
Shiyin Wei
Jiachang Chi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555287

Original Research

Accepted on 17 Feb 2025

Radical hemithorax radiotherapy induces an increase in circulating PD-1 + T lymphocytes and in the soluble levels of PD-L1 in Malignant Pleural Mesothelioma patients: a possible synergy with PD-1/PD-L1 targeting treatment?

in Cancer Immunity and Immunotherapy

Alberto Revelant
Francesca Gessoni
Marcella Montico
Raja Dhibi
Giulia Brisotto
Martina Zanchetta
Veronica Paduano
Filippo Sperti
Chiara Evangelista
Fabiana Giordari

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534766

Original Research

Accepted on 17 Feb 2025

Tiltle:The relationship between systemic therapies and low skeletal muscle mass in patients with intermediate and advanced hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Jingjing Chen
Mei Liu
Xueying Huang
Qiaoxin Wei
Songtao Liu
Wenyan Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557839

Original Research

Accepted on 17 Feb 2025

Exploration of SUSD3 in pan-cancer: studying its role, predictive analysis, and biological significance in various malignant tumors in humans

in Cancer Immunity and Immunotherapy

Fei Zhong
Shining Mao
Shuangfu Peng
Jiaqi Li
Yanteng Xie
Ziqian Xia
Chao Chen
Shasha Zhang
Aijun Sun
Shiyan Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1521965

Original Research

Accepted on 17 Feb 2025

Establishment and validation of a survival prediction model for stage IV non-small cell lung cancer: a real-world study

in Cancer Immunity and Immunotherapy

Keao Zheng
Zhiying Hao
Feng Li
Jing Zeng
Junyan Zhang
Tingting Xu
Fangyu Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1508721

Case Report

Accepted on 17 Feb 2025

Camrelizumab plus gemcitabine followed by concurrent chemoradiation for HPV-positive and PD-L1-positive tonsillar squamous cell carcinoma: a case report

in Cancer Immunity and Immunotherapy

Xuesong Li
Bianhong Wang
Hao Liu
Zhuo Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528198

Case Report

Accepted on 17 Feb 2025

Complete Response of Advanced Esophageal Squamous Cell Carcinoma (ESCC) with First-Line Chemotherapy Combined with Immunotherapy: A Case Report

in Cancer Immunity and Immunotherapy

Yahong Wei
Shaohui Han
Yabin Shi
Yaxing Li
Qi Zhang
Lijuan Zhang
Yan Cheng
Xiaolu Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1511663

Case Report

Accepted on 17 Feb 2025

Multiple Cutaneous Keratoacanthoma-like Lesions in a Colorectal Cancer Patient Treated with Sintilimab

in Cancer Immunity and Immunotherapy

Shiyi Li
Xianhui Ye
Xiaofen Li
Yu Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535220

Original Research

Published on 17 Feb 2025

Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal cancer

in Cancer Immunity and Immunotherapy

Ming Zhang
Yani Su
Pengfei Wen
Xiaolong Shao
Peng Yang
Peng An
Wensen Jing
Lin Liu
Zhi Yang
Mingyi Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539630

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Editorial

Published on 17 Feb 2025

Editorial: Understanding bladder tumor microenvironment to optimize immunotherapy

in Cancer Immunity and Immunotherapy

Mathieu Rouanne
Laurent Derré

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566407

157 views

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Articles

Targeting stemness pathways modulates macrophage polarization and reprograms the tumor microenvironment

Case Report: Severe Pneumocystis jirovecii Pneumonia Following Zuberitamab Treatment in Autoimmune Hemolytic Anemia

PARylation-Mediated Post-Transcriptional Modifications in Cancer Immunity and Immunotherapy

Exploring NUP62's Role in Cancer Progression, Tumor Immunity, and Treatment Response: Insights from Multiomics Analysis

The role of intestinal macrophage polarization in colitis-associated colon cancer

Immune Checkpoint Inhibitors and Cancer-Related Cognitive Decline: A Propensity Score Matched Analysis in active Chemotherapy Patients

Metabolic Reprogramming Shapes the Immune Microenvironment in Pancreatic Adenocarcinoma: Prognostic Implications and Therapeutic Targets

Radical hemithorax radiotherapy induces an increase in circulating PD-1 + T lymphocytes and in the soluble levels of PD-L1 in Malignant Pleural Mesothelioma patients: a possible synergy with PD-1/PD-L1 targeting treatment?

Tiltle:The relationship between systemic therapies and low skeletal muscle mass in patients with intermediate and advanced hepatocellular carcinoma

Exploration of SUSD3 in pan-cancer: studying its role, predictive analysis, and biological significance in various malignant tumors in humans

Establishment and validation of a survival prediction model for stage IV non-small cell lung cancer: a real-world study

Camrelizumab plus gemcitabine followed by concurrent chemoradiation for HPV-positive and PD-L1-positive tonsillar squamous cell carcinoma: a case report

Complete Response of Advanced Esophageal Squamous Cell Carcinoma (ESCC) with First-Line Chemotherapy Combined with Immunotherapy: A Case Report

Multiple Cutaneous Keratoacanthoma-like Lesions in a Colorectal Cancer Patient Treated with Sintilimab

Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal cancer

Editorial: Understanding bladder tumor microenvironment to optimize immunotherapy