Frontiers in Immunology | Cancer Immunity and Immunotherapy

Correction

Accepted on 18 Dec 2025

Correction: TACE-HAIC versus HAIC combined with TKIs and ICIs for hepatocellular carcinoma with a high tumor burden—a propensity-score matching comparative study

in Cancer Immunity and Immunotherapy

Chun-xue Wu
yunlong Dong
Xinge Li
Wenbo Shao
Guangshun Wang
Huiyong Wu
Xu Chang

Frontiers in Immunology

269 views

Original Research

Accepted on 18 Dec 2025

From multi-omics to functional validation: the PTMRS stratifies TME and positions PDGFRB in CRC biology

in Cancer Immunity and Immunotherapy

Yanhong Liu
Chao Lu
Luchun Hua
Hankun Hao
Qijing Zhang
Zongyou Zou
Jianbin Xiang
Yaping Wang

Frontiers in Immunology

122 views

Original Research

Published on 18 Dec 2025

Multi-omics profiling unravel the immune landscape diversity by prognostic signatures of immunotherapy response in triple-negative breast cancer

in Cancer Immunity and Immunotherapy

Rong Chai
Ziting Zhang
Zheng Gong
Qi Li
Chunyan Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1735893

618 views

Review

Published on 18 Dec 2025

TIR domain proteins: regulatory mechanisms in the tumor immune microenvironment, clinical translation strategies, and prospects for precision therapy applications

in Cancer Immunity and Immunotherapy

Jiatian Lou
Chenlei Gong
Xiaotao Gao
Jiaren Zhou
Qiyuan Wu
Xiaoliang Zheng
Liyan Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1695754

587 views

Original Research

Published on 18 Dec 2025

Targeting highly attenuated IL-18 to PD-1 for enhanced anti-tumor activity

in Cancer Immunity and Immunotherapy

Xueyuan Zhou
Felix Klaus Geyer
Jeffrey Takimoto
Harald Kolmar
Brian Rabinovich

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718321

1,759 views

Original Research

Published on 18 Dec 2025

LOX1-mediated supramolecular self-assembly nanomedicine for microsatellite-stable colorectal cancer towards reactivating anti-tumor immunity

in Cancer Immunity and Immunotherapy

Xin Wei
Yuyan Guo
Jianyuan Lei
Na Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1737031

499 views

Original Research

Published on 18 Dec 2025

Impact of inotuzumab ozogamicin as bridging therapy and tumor burden in CAR-T therapy for B-acute lymphoblastic leukemia

in Cancer Immunity and Immunotherapy

Patricia Alcalde-Mellado
Victoria Ruiz-Maldonado
Javier Delgado-Serrano
Luzalba Sanoja-Flores
Marta Reinoso-Segura
Laura Pérez-Ortega
Belén Sierro-Martínez
Estefanía García-Guerrero
Concepción Pérez de Soto
José María Pérez-Hurtado

Frontiers in Immunology

doi 10.3389/fimmu.2025.1725878

698 views

Review

Published on 18 Dec 2025

New insights into combined immunotherapy for hepatocellular carcinoma associated with liver cirrhosis

in Cancer Immunity and Immunotherapy

Yufan Liu
Kexin Cong
Qiao Li
Dan Zhang
Jiyao Sheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1741398

418 views

Original Research

Published on 18 Dec 2025

Evaluation of warning strategies for paraneoplastic neurological syndromes associated with PD-1/PD-L1 inhibitors

in Cancer Immunity and Immunotherapy

Zhuangzhuang Ren
Yudan Liu
Jianguo Liu
Xiaokun Qi
Feng Qiu
Chenjing Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1670751

353 views

Review

Accepted on 17 Dec 2025

The Tumor Microenvironment: Adding pieces to the puzzle

in Cancer Immunity and Immunotherapy

Dolores Aguilar-Cazares
Mario Perez-Medina
Jesús Jareb Benito-Lopez
Miriam Galicia
Manuel Meneses-Flores
Angel Camarena
Jose Sullivan Lopez-Gonzalez

Frontiers in Immunology

163 views

Systematic Review

Accepted on 17 Dec 2025

To Substitute or Not? A Systematic Review of Immunoglobulin Replacement Therapy in Multiple Myeloma Patients Treated with Bispecific Antibodies

in Cancer Immunity and Immunotherapy

Juni Songe Paulsen
Tobias S Slørdahl

Frontiers in Immunology

144 views

Review

Accepted on 17 Dec 2025

Current Update on Toll-like Receptor and Prostate Cancer: A Decade of Progress and Emerging Insights

in Cancer Immunity and Immunotherapy

Jahnavi Janjirala
Matthew Blanton
Kenneth S. Ramos
Dekai Zhang

Frontiers in Immunology

123 views

Review

Accepted on 17 Dec 2025

Immunotherapy in Endometrial Cancer: Mechanisms, Clinical Evidence, and Future Directions

in Cancer Immunity and Immunotherapy

Mengyi Lian
Chengwei Zhang
Tianye Li
Aiming Wang

Frontiers in Immunology

258 views

Correction

Accepted on 17 Dec 2025

Correction: Association between statin use and immune-related adverse events in patients treated with immune checkpoint inhibitors: analysis of the FAERS database

in Cancer Immunity and Immunotherapy

HuaJu Yang
Rendong Huang
Ping Zhang
Yingtong Liu
Zheran Liu
Jiagang He
Xingchen Peng

Frontiers in Immunology

256 views

Systematic Review

Accepted on 17 Dec 2025

Effects of Exercise on Angiogenesis Biomarkers in Cancer Patients: A Systematic Review and Meta-analysis

in Cancer Immunity and Immunotherapy

Jingyu Wang
Yuxuan He
Ziqian Wang
Zhouluo Wang
Yu Sun
Kyung-Hee Lee
Jae-Young Choi

Frontiers in Immunology

156 views

Original Research

Accepted on 17 Dec 2025

Identification of a prognostic signature based on immunogenic adverse events-related genes to guide therapy for non-small cell lung cancer

in Cancer Immunity and Immunotherapy

Jun Zhu
Qing Ye
Li Gang
Lidong Liu
Shushu Tian
Shuangyan Li
Maoru Wen
Luying Shen
Jiang Wang
Xinmao Song

Frontiers in Immunology

119 views

Original Research

Accepted on 17 Dec 2025

Single-cell transcriptomics reveals a novel mechanism of RDH16 regulating immune infiltration in hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Zhenzhen Zhang
Rui Fan
Jing Ma
Dehui Li
Yan Jiang
Fahui Liu
Qiming Gong

Frontiers in Immunology

143 views

Mini Review

Published on 17 Dec 2025

Targeting glioma-associated microglia and macrophages: a new frontier in glioblastoma immunotherapy

in Cancer Immunity and Immunotherapy

Bingyang Wang
Cong Li
Jiatong Gu
Xiaojie Wang
Mingjuan Xun
Bin Jiang
Jun Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726440

786 views

Original Research

Published on 17 Dec 2025

Tumor intrinsic properties dictate Fc receptor expression and cancer cachexia associated increase in checkpoint inhibitor clearance

in Cancer Immunity and Immunotherapy

Bryan C. Remaily
Greg Young
Hannah Lathrop
Justin Thomas
Kyeongmin Kim
Trang T. Vu
Adeoluwa Adeluola
Camille Stanton
Gillian Mulcahy
Zhiliang Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669979

926 views

Review

Published on 17 Dec 2025

CD147 at the crossroads of glycoprotein networks, metabolic reprogramming, and metastatic progression

in Cancer Immunity and Immunotherapy

Tz-Syuan Su
Jiunn-Wei Wang
Yu-Li Su
Ming-Hong Lin
Hsin-Ying Clair Chiou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1727125

574 views

Original Research

Published on 17 Dec 2025

A multidimensional data-driven approach to surgical plan optimization and postoperative residual tumor prediction in ovarian cancer

in Cancer Immunity and Immunotherapy

Lin Yang
Tianhui He
Ping Yu
Chunliang Shang
Jing Wang
Qinkun Sun
Yi Xie
Jianling Yang
Hongyan Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705428

520 views

Original Research

Published on 17 Dec 2025

Early intrathecal dexamethasone and methotrexate as an effective approach for immune effector cell-associated neurotoxicity syndrome after CAR-T cell therapies

in Cancer Immunity and Immunotherapy

Juanxia Meng
Hairong Lyu
Zhao Wang
Xue Bai
Haibo Zhu
Yedi Pu
Xiaoyuan He
Xia Xiao
Mingfeng Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716317

539 views

Original Research

Published on 17 Dec 2025

Prognostic significance of hematological parameters and albumin in BCMA-targeted CAR-T therapy for multiple myeloma

in Cancer Immunity and Immunotherapy

Liansheng Jiang
Hefei Ren
Zhiqing Ke
Yaoting Liu
Chang Liu
Lin Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1703394

398 views

Review

Published on 17 Dec 2025

Remodeling the tumor microenvironment: regulatory effects of β-sitosterol and luteolin on the immunosuppressive milieu in endometrial carcinoma and implications for combinatorial immunotherapy

in Cancer Immunity and Immunotherapy

Guojie Ji
Pengbo Wang
Zhihong Kong
Xiangxiang Cao
Xiaowei Shi
Huigen Feng
Huanhuan Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669606

587 views

9,296 articles

articles

Correction: TACE-HAIC versus HAIC combined with TKIs and ICIs for hepatocellular carcinoma with a high tumor burden—a propensity-score matching comparative study

From multi-omics to functional validation: the PTMRS stratifies TME and positions PDGFRB in CRC biology

Multi-omics profiling unravel the immune landscape diversity by prognostic signatures of immunotherapy response in triple-negative breast cancer

TIR domain proteins: regulatory mechanisms in the tumor immune microenvironment, clinical translation strategies, and prospects for precision therapy applications

Targeting highly attenuated IL-18 to PD-1 for enhanced anti-tumor activity

LOX1-mediated supramolecular self-assembly nanomedicine for microsatellite-stable colorectal cancer towards reactivating anti-tumor immunity

Impact of inotuzumab ozogamicin as bridging therapy and tumor burden in CAR-T therapy for B-acute lymphoblastic leukemia

New insights into combined immunotherapy for hepatocellular carcinoma associated with liver cirrhosis

Evaluation of warning strategies for paraneoplastic neurological syndromes associated with PD-1/PD-L1 inhibitors

The Tumor Microenvironment: Adding pieces to the puzzle

To Substitute or Not? A Systematic Review of Immunoglobulin Replacement Therapy in Multiple Myeloma Patients Treated with Bispecific Antibodies

Current Update on Toll-like Receptor and Prostate Cancer: A Decade of Progress and Emerging Insights

Immunotherapy in Endometrial Cancer: Mechanisms, Clinical Evidence, and Future Directions

Correction: Association between statin use and immune-related adverse events in patients treated with immune checkpoint inhibitors: analysis of the FAERS database

Effects of Exercise on Angiogenesis Biomarkers in Cancer Patients: A Systematic Review and Meta-analysis

Identification of a prognostic signature based on immunogenic adverse events-related genes to guide therapy for non-small cell lung cancer

Single-cell transcriptomics reveals a novel mechanism of RDH16 regulating immune infiltration in hepatocellular carcinoma

Targeting glioma-associated microglia and macrophages: a new frontier in glioblastoma immunotherapy

Tumor intrinsic properties dictate Fc receptor expression and cancer cachexia associated increase in checkpoint inhibitor clearance

CD147 at the crossroads of glycoprotein networks, metabolic reprogramming, and metastatic progression

A multidimensional data-driven approach to surgical plan optimization and postoperative residual tumor prediction in ovarian cancer

Early intrathecal dexamethasone and methotrexate as an effective approach for immune effector cell-associated neurotoxicity syndrome after CAR-T cell therapies

Prognostic significance of hematological parameters and albumin in BCMA-targeted CAR-T therapy for multiple myeloma

Remodeling the tumor microenvironment: regulatory effects of β-sitosterol and luteolin on the immunosuppressive milieu in endometrial carcinoma and implications for combinatorial immunotherapy