Frontiers in Immunology | Comparative Immunology

Original Research

Published on 10 Jul 2025

Grass carp Trim47 restricts GCRV infection via SPRY domain-mediated autophagic degradation of nonstructural proteins and disruption of viral inclusion bodies

in Comparative Immunology

Wei Yan
Yang Chen
Dong Yan
Jie Zhang
Ming Xian Chang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623014

102 views

Original Research

Published on 09 Jul 2025

Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomics

in Comparative Immunology

Xinchi Shang
Xinghua Che
Kai Ma
Bo Ma
Huizhi Sun
Wenhua Wu
Hailong He
Meiqi Xing
Wei Xu
Yongquan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633174

199 views

Original Research

Accepted on 07 Jul 2025

Programmed Cell Death Signatures (PCDS)-Driven Microglial Transformation in Alzheimer's Disease: Single-Cell Transcriptomics and Functional Validation

in Comparative Immunology

Mi-Mi Li
Ying-Xia Yang
Ya-Li Huang
Shu-Juan Wu
Wan-Li Huang
Li-Chao Ye
Ying-Ying Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610717

Original Research

Published on 02 Jul 2025

Protective IgM-mediated immunity against Vibrio anguillarum in Atlantic cod with evolutionary losses of mhc class II and cd4

in Comparative Immunology

Alexandra Jonsson
Adrián López-Porras
Simen Foyn Nørstebø
Naomi Croft Guslund
Henning Sørum
Shuo-Wang Qiao
Finn-Eirik Johansen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579541

436 views

Editorial

Published on 01 Jul 2025

Editorial: Environmental stressors and aquatic animal immune system function

in Comparative Immunology

Christopher J. Martyniuk
Erchao Li
Matthew L. Rise

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610969

327 views

Original Research

Accepted on 30 Jun 2025

Integrated transcriptomic and immune enzymatic analyses uncover coordinated immunometabolic responses in large yellow croaker (Larimichthys crocea) to Metanophrys sp. infection

in Comparative Immunology

Ruiling Zhou
Kangshuai Sun
Xiao Xie
Fei Yin
Jorge Galindo-Villegas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636453

124 views

Original Research

Accepted on 27 Jun 2025

Feed Status and Skin Injury Modulate Immunopathology, Global Gene Expression, and Survival in Channel Catfish During Virulent Aeromonas hydrophila Infection

in Comparative Immunology

Yesutor Soku
Miles D Lange
Jason Abernathy
Nithin M Sankappa
Craig Shoemaker
Karl Hayden
Linnea K Andersen
Ida Phillips
Toufic Nashar
Temesgen Samuel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642531

128 views

Original Research

Accepted on 26 Jun 2025

Dietary Supplementation with Nano-Zinc Modulates Expression of the Antiviral Immune Gene IRF3-A Novel Report

in Comparative Immunology

Amrita Tah
ARUNA PAL
Achinta Mahato
Debasis De
Argha Chakraborty
MANTI DEBNATH
Sovan Roy
Paresh Nath Chatterjee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583956

Review

Published on 25 Jun 2025

RNA-sequencing studies suggest that microRNAs and alternative splicing of pre-mRNAs modulate immune and inflammatory responses in Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis

in Comparative Immunology

Gerard Badia-Bringué
Marta Alonso-Hearn

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597736

457 views

Original Research

Published on 24 Jun 2025

ISGylation and E3 ubiquitin ligases: an Atlantic salmon genetic perspective

in Comparative Immunology

Unni Grimholt
Hilde Sindre
Arvind Y. M. Sundaram

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554680

547 views

Review

Published on 23 Jun 2025

The battle between bacterial infection and autophagy in aquatic animals

in Comparative Immunology

Qi Wang
He Xu
Jiaxue Jin
Yankai Yang
Lothar Jänsch
Senlin Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1614182

549 views

Brief Research Report

Published on 23 Jun 2025

A fish-specific antimicrobial peptide MsPiscidin2 inactivates MSRV and confers protection in largemouth bass

in Comparative Immunology

Chenjie Fei
Ziwen Wang
Yang Hu
Li Nie
Jiong Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629256

523 views

Review

Published on 20 Jun 2025

Toward understanding sexual immune dimorphism in humans

in Comparative Immunology

Tomasz J. Nowak
Michael P. Muehlenbein

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570565

702 views

Original Research

Published on 18 Jun 2025

Peptidoglycan derived from Lacticaseibacillus rhamnosus and Lactobacillus acidophilus suppress TLR2/1-mediated inflammation in bovine endometrial epithelial cells

in Comparative Immunology

Elham Waehama
Kenji Fukuda
Alireza Mansouri
Malinda Hulugalla
Ihshan Akthar
Mohamed Samy Yousef
Akio Miyamoto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622307

937 views

Original Research

Published on 18 Jun 2025

Functional feed ingredients modulate the immune response of RTgutGC cells to LPS-induced inflammation

in Comparative Immunology

Malene Malchus Fosse
Laura Rivera Méndez
Tania Rodríguez-Ramos
Brian Dixon
Henrik Sundh
Rolf Erik Olsen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616076

771 views

Original Research

Published on 17 Jun 2025

Subclinical ketosis in postpartum dairy cows alters the adipose tissue immunological profile in a depot-specific manner

in Comparative Immunology

Tainara C. Michelotti
Bruno C. Menarim
Alexandra P. Tegeler
Jean F. Fiallo Diez
Vinicius S. Machado
Yava Jones-Hall
Oscar J. Benitez
Shavahn C. Loux
Clarissa Strieder-Barboza

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578669

835 views