Frontiers in Immunology | Comparative Immunology

Original Research

Published on 06 Jun 2025

Culicoides allergens expressed in insect cells induce sulphidoleukotriene release from peripheral blood leukocytes of horses affected with insect bite hypersensitivity

in Comparative Immunology

Sigridur Jonsdottir
Sara Björk Stefansdottir
Jelena Mirkovitch
Anja Ziegler
Sigurbjörg Torsteinsdottir
Eliane Marti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597233

1,143 views

Original Research

Published on 05 Jun 2025

Unveiling regulatory variants in the blood transcriptome and their association with immunity traits in pigs

in Comparative Immunology

Teodor Jové-Juncà
Daniel Crespo-Piazuelo
Carles Hernández-Banqué
Olga González-Rodríguez
Lingzhao Fang
Raquel Quintanilla
Maria Ballester

Frontiers in Immunology

doi 10.3389/fimmu.2025.1582982

1,026 views

Original Research

Published on 05 Jun 2025

Identification of the microglia-associated signature in experimental autoimmune encephalomyelitis

in Comparative Immunology

Yan Wu
Jianhong Wang
Bo Chen
Yuxue Guo
Ping Gan
Yanbing Han

Frontiers in Immunology

doi 10.3389/fimmu.2025.1581878

1,104 views

Original Research

Published on 03 Jun 2025

Inactivated Rothia nasimurium promotes a persistent antiviral immune status in porcine alveolar macrophages

in Comparative Immunology

Aida Tort-Miró
Uxía Alonso
Beatriz Martín-Mur
Jordana Muñoz-Basagoiti
Yan Zeng
David Marín-Moraleda
Enrique Ezcurra
Sergio Montaner-Tarbes
María J. Navas
Marta Muñoz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1584092

1,369 views

Review

Published on 03 Jun 2025

Autophagy in aquatic animals: mechanisms, implications, and future directions

in Comparative Immunology

Md. Abu Kawsar
Diponkor Adikari
Yang Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612178

1,231 views

Original Research

Published on 30 May 2025

Evolutionary insights into Interleukin-12 family targets across 405 species

in Comparative Immunology

Weibin Wang
Dawei Li
Kaiyong Luo
Baozheng Chen
Xuzhen Li
Tingting Hao
Dazhong Guo
Yang Dong
Ya Ning

Frontiers in Immunology

doi 10.3389/fimmu.2025.1584460

984 views

Original Research

Published on 28 May 2025

PD-1 is conserved from sharks to humans: new insights into PD-1, PD-L1, PD-L2, and SHP-2 evolution

in Comparative Immunology

Ryohei Kondo
Kohei Kondo
Kei Nabeshima
Akihiko Nishikimi
Yasumasa Ishida
Toshiaki Shigeoka
Johannes M. Dijkstra

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573492

1,932 views

Original Research

Published on 26 May 2025

Host-driven evolution of PCV2: insights into genetic diversity and adaptation

in Comparative Immunology

Giovanni Franzo
Matteo Legnardi
Francesca Poletto
Riccardo Baston
Mattia Cecchinato
Michele Drigo
Claudia Maria Tucciarone

Frontiers in Immunology

doi 10.3389/fimmu.2025.1577436

1,088 views

Original Research

Published on 26 May 2025

Integrated transcriptomic and microbiomic analyses reveal mechanisms of Decapod iridescent virus 1 resistance in Macrobrachium rosenbergii

in Comparative Immunology

Jingwen Hao
Yukun Jie
Zhibin Lu
Tiantian Ye
Jilun Meng
Cui Liu
Junjun Yan
Yutong Zheng
Zaijie Dong
Zhimin Gu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611481

983 views

Original Research

Published on 21 May 2025

Alleviating effect of vine tea on Aeromonas hydrophila infection revealed by small RNA transcriptome analyses of loach liver

in Comparative Immunology

Wenqing Lai
Yuqin Qiu
Shengnan Pan
Aijun Wan
Xueyang Wang
Dingding Lv
Lishang Dai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1584985

846 views

Original Research

Published on 20 May 2025

Development of caninized anti-CTLA-4 antibody as salvage combination therapy for anti-PD-L1 refractory tumors in dogs

in Comparative Immunology

Naoya Maekawa
Satoru Konnai
Kei Watari
Hiroto Takeuchi
Takeshi Nakanishi
Taro Tachibana
Kenji Hosoya
Sangho Kim
Ryohei Kinoshita
Ryo Owaki

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570717

2,092 views

Original Research

Published on 19 May 2025

TLR4 and prostaglandin pathways at the crossroads of endotoxemia-induced lipolysis

in Comparative Immunology

Miguel Chirivi
Ursula Abou-Rjeileh
Madison Myers
Jair Parales-Giron
Lynn Worden
Adam L. Lock
G. Andres Contreras

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591210

1,341 views
1 citation

Original Research

Published on 19 May 2025

Evidence for trans-generational immune priming against Vibrio splendidus in the oyster Crassostrea gigas

in Comparative Immunology

Xiaorui Song
Weilin Wang
Miren Dong
Chang Liu
Chuanyan Yang
Lingling Wang
Linsheng Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1536562

879 views

Original Research

Published on 15 May 2025

Bioinformatics analyses of the proteome of Holothuria tubulosa coelomic fluid and the first evidence of primary cilium in coelomocyte cells

in Comparative Immunology

Laura La Paglia
Manuela Mauro
Vincenzo Arizza
Alfonso Urso
Sugár Simon
Laszlo Drahos
Vita di Stefano
Claudio Luparello
Mirella Vazzana
Aiti Vizzini

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539751

1,116 views
1 citation

Original Research

Published on 15 May 2025

Dietary phosphorus restriction induced phospholipid deficiency, endoplasmic reticulum stress, inflammatory response and gut microbiota disorders in Lateolabrax maculatus

in Comparative Immunology

Zixiang Wu
Jiarong Guo
Kangle Lu
Kai Song
Ling Wang
Ruijuan Ma
Chunxiao Zhang
Xueshan Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1592806

947 views

Original Research

Accepted on 12 May 2025

Protective IgM-mediated immunity against Vibrio anguillarum in Atlantic cod with evolutionary losses of mhc class II and cd4

in Comparative Immunology

Finn-Eirik Johansen
Alexandra Jonsson
Adrian Lopez Porras
Simen Foyn Nørstebø
Naomi Croft Guslund
Rune Henning Sørum
Shuo-Wang Qiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579541

213 views