Frontiers in Immunology | Comparative Immunology

Original Research

Published on 29 Sep 2025

Resveratrol suppresses OSCC invasion and migration by regulating macrophage polarization via Syk signaling pathway

in Comparative Immunology

Weibo Li
Ying Qi
Yafei Li
Lu Liu
Xiaodan Dong
Bo Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1660851

1,771 views

Original Research

Published on 25 Sep 2025

Metformin-associated gut microbiota remodeling correlates with reinvigorated splenic immunity in aged mice: microbiome-immune crosstalk via the gut-spleen axis

in Comparative Immunology

Shu-Qin Ding
Xin-Yi Lyu
Shi-Yu Zhou
Yi-Wan Fang
Hao-Xin Ji
Jiang-Yan Li
He-Zuo Lü

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633486

5,257 views

Original Research

Published on 25 Sep 2025

Dynamic immune and molecular responses to chronic heat stress in blood and peripheral blood mononuclear cells of dairy cows

in Comparative Immunology

Franziska Koch
Torsten Viergutz
Christa Kühn
Björn Kuhla

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633453

1,977 views

Original Research

Published on 23 Sep 2025

Fungal communities in Florida salt marsh mosquito midguts vary between species and over time but have low structure

in Comparative Immunology

Daniel W. Pérez-Ramos
Eric P. Caragata

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648091

1,707 views

Original Research

Published on 23 Sep 2025

Deciphering the regulatory mechanisms of honeysuckle (Lonicera japonica) on lipopolysaccharide-induced inflammatory responses in loach (Misgurnus anguillicaudatus) through small RNA sequencing

in Comparative Immunology

Ruike Fan
Zihan Sun
Lishang Dai
Xiajuan Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683771

1,961 views

Original Research

Published on 18 Sep 2025

Anthropogenic noise exposure suppresses the immune response in Mytilus spp. following Vibrio splendidus challenge

in Comparative Immunology

Ambre F. Chapuis
Matthew A. Wale
Morgan Bailey
Hannah M. Farley
Tim P. Bean
Tim Regan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657667

2,725 views

Original Research

Published on 12 Sep 2025

Parenteral micronutrient supplementation enhances mammary immune function and colostrum–milk quality by modulating cytokine profiles and oxidative stress in transition crossbred cows

in Comparative Immunology

Yallappa M. Somagond
Pravasini Das
Ajay Kumar Dang
Dhawal K. Yadav
Priyanka M. Kittur
Bibhudatta S.K. Panda
Pooja Devi
Aarti Kamboj
Mohanned Naif Alhussien

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669246

2,891 views

Review

Published on 11 Sep 2025

Local and systemic immunological response in feline chronic gingivostomatitis: a critical review

in Comparative Immunology

Rafael S. Lopes
Pedro P. Carvalho
Maria A. Pires
Paulo Rodrigues-Santos
Eduardo Costa
João F. Requicha

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572631

3,193 views

Editorial

Published on 08 Sep 2025

Editorial: The roles of autophagy and cell death in the host immune response in aquatic animals

in Comparative Immunology

Quanyuan Wan
Junji Zhu
Zhendong Qin
Yongyao Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1688035

1,525 views

Original Research

Published on 08 Sep 2025

Polyfunctionality of CD4+ T lymphocytes in buffaloes and cattle: comparative antigen-specific cytokine responses in bovine tuberculosis infection

in Comparative Immunology

Susana Flores-Villalva
Giovanna De Matteis
Francesco Grandoni
Maria Carmela Scatà
Anna Donniacuo
Lorena Schiavo
Giulia Franzoni
Piera Mazzone
Mahmoud Elnaggar
Esterina De Carlo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608065

1,960 views

Original Research

Published on 05 Sep 2025

Chronic airway inflammation in Drosophila lacking the A20-like protein Trabid

in Comparative Immunology

Judith Bossen
Mirjam Knop
Xiao Niu
Marcus Thiedmann
Ruben Prange
Navid Tahanzadeh
Sören Franzenburg
Iris Bruchhaus
Holger Heine
Thomas Roeder

Frontiers in Immunology

doi 10.3389/fimmu.2025.1564386

1,781 views

Original Research

Published on 05 Sep 2025

Evolutionary analysis of CD300A and CD300C paired receptors in primates

in Comparative Immunology

Carolina Dias
Francesca Levi-Schaffer
Pedro José Esteves

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633323

1,742 views

Correction

Published on 04 Sep 2025

Correction: Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomics

in Comparative Immunology

Xinchi Shang
Xinghua Che
Kai Ma
Bo Ma
Huizhi Sun
Wenhua Wu
Hailong He
Meiqi Xing
Wei Xu
Yongquan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692659

993 views

Original Research

Published on 03 Sep 2025

Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis

in Comparative Immunology

Weiwei Zheng
Yadong Chen
Tao Yang
Zhihong Liu
Dong Xu
Huizong Han
Yaning Wang
Xiaoqing Xi
Tengteng Wang
Songlin Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644885

2,532 views

Original Research

Published on 03 Sep 2025

Chronic stress synergizes with Listeria monocytogenes to promote intestinal adenomagenesis via myeloid-derived suppressor cells

in Comparative Immunology

Pingqian Qi
Lili Yin
Ruijia Wei
Siyuan Yang
Ziqing Liu
Ping Huang
Qiwen Yu
Suyi Xiong
Mengmeng Wang
Yanjuan Deng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653548

2,295 views
1 citation

Review

Published on 02 Sep 2025

NOD-like receptors in fish: evolution, structure, immune signaling, and targeting for aquaculture vaccine adjuvants

in Comparative Immunology

Banikalyan Swain
Kavi R. Miryala

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665071

3,370 views
1 citation

Original Research

Published on 02 Sep 2025

Evaluating single nucleotide polymorphisms in beta - 2 - microglobulin – a theoretical study

in Comparative Immunology

Ammar K. Daoud
Wafa’ A. Alqarqaz
Majduleen M. Al Okor

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622416

1,682 views

Original Research

Published on 01 Sep 2025

The high temperature stress responses in the hepatopancreas of Litopenaeus vannamei: from immune dysfunction to metabolic remodeling cascade

in Comparative Immunology

Yafei Duan
Meng Xiao
Yun Wang
Jianhua Huang
Yukai Yang
Hua Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631655

2,339 views
2 citations

Original Research

Published on 29 Aug 2025

Annotation of gene loci and analysis of expression diversity in sheep immunoglobulin

in Comparative Immunology

Mingli Wu
Fuwen Chen
Xiaoqin Tang
Jingxuan Li
Haidong Zhao
Yuelang Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1643380

1,469 views

Original Research

Published on 29 Aug 2025

IgT and IgD dominance in the teleost central nervous system

in Comparative Immunology

Samuel Vicente-Gil
Valeria Pianese
Esther Morel
Beatriz Abós
Pablo Jiménez-Barrios
Pedro Perdiguero
Diana Martín
Rocío Simón
Simona Picchietti
Giuseppe Scapigliati

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657738

2,294 views
1 citation

Original Research

Published on 27 Aug 2025

Depletion of myeloid-derived suppressor cells alleviates kidney damage in murine membranous nephropathy

in Comparative Immunology

Huimin Li
Anhui Wei
Zhanchuan Ma
Li Yang
Xia Xiao
Chang Liu
Chunyan Teng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623613

1,762 views

Editorial

Published on 27 Aug 2025

Editorial: Commending 20 years since the formal discovery of immune priming: the innate immune memory

in Comparative Immunology

Jorge Contreras-Garduño
Joachim Kurtz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652666

1,268 views

Original Research

Published on 27 Aug 2025

The impact of multistrain probiotics (Leuconostoc mesenteroides, Lactococcus lactis) on African catfish (Clarias gariepinus) gut microbiota, immunological response, and growth performance

in Comparative Immunology

Assel Paritova
Altay Ussenbayev
Rauan Abdessan
Zhenisgul Seitkaliyevna Assauova
Gulnur Berikovna Kuzembekova
Gulzhan Omarbekova
Aiken Sansyzbaevna Karabassova
Aigul Jenisbekkyzy Kassen
Zhuldyzay Kenzhebekova
Gulmira Alibayevna Abulgazimova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625199

1,808 views

Editorial

Published on 26 Aug 2025

Editorial: Immunovirology in aquatic animals

in Comparative Immunology

Carolina Johnstone
Elena Chaves-Pozo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655117

1,395 views

1,425 articles

articles

Resveratrol suppresses OSCC invasion and migration by regulating macrophage polarization via Syk signaling pathway

Metformin-associated gut microbiota remodeling correlates with reinvigorated splenic immunity in aged mice: microbiome-immune crosstalk via the gut-spleen axis

Dynamic immune and molecular responses to chronic heat stress in blood and peripheral blood mononuclear cells of dairy cows

Fungal communities in Florida salt marsh mosquito midguts vary between species and over time but have low structure

Deciphering the regulatory mechanisms of honeysuckle (Lonicera japonica) on lipopolysaccharide-induced inflammatory responses in loach (Misgurnus anguillicaudatus) through small RNA sequencing

Anthropogenic noise exposure suppresses the immune response in Mytilus spp. following Vibrio splendidus challenge

Parenteral micronutrient supplementation enhances mammary immune function and colostrum–milk quality by modulating cytokine profiles and oxidative stress in transition crossbred cows

Local and systemic immunological response in feline chronic gingivostomatitis: a critical review

Editorial: The roles of autophagy and cell death in the host immune response in aquatic animals

Polyfunctionality of CD4+ T lymphocytes in buffaloes and cattle: comparative antigen-specific cytokine responses in bovine tuberculosis infection

Chronic airway inflammation in Drosophila lacking the A20-like protein Trabid

Evolutionary analysis of CD300A and CD300C paired receptors in primates

Correction: Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomics

Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis

Chronic stress synergizes with Listeria monocytogenes to promote intestinal adenomagenesis via myeloid-derived suppressor cells

NOD-like receptors in fish: evolution, structure, immune signaling, and targeting for aquaculture vaccine adjuvants

Evaluating single nucleotide polymorphisms in beta - 2 - microglobulin – a theoretical study

The high temperature stress responses in the hepatopancreas of Litopenaeus vannamei: from immune dysfunction to metabolic remodeling cascade

Annotation of gene loci and analysis of expression diversity in sheep immunoglobulin

IgT and IgD dominance in the teleost central nervous system

Depletion of myeloid-derived suppressor cells alleviates kidney damage in murine membranous nephropathy

Editorial: Commending 20 years since the formal discovery of immune priming: the innate immune memory

The impact of multistrain probiotics (Leuconostoc mesenteroides, Lactococcus lactis) on African catfish (Clarias gariepinus) gut microbiota, immunological response, and growth performance

Editorial: Immunovirology in aquatic animals