Frontiers in Immunology | Comparative Immunology

Original Research

Published on 19 Nov 2025

Different kinetics of humoral response against individual antigens in the ovine model of Toxoplasma gondii infection and its pathological association

in Comparative Immunology

Paula Formigo
Ignacio Gual
Germán J. Cantón
Luisa F. Mendoza Morales
Emiliano Sosa
Agustina Soto Cabrera
Valeria Scioli
Claudia Morsella
Valeria A. Sander
Dadin P. Moore

Frontiers in Immunology

doi 10.3389/fimmu.2025.1701645

1,071 views

Original Research

Published on 11 Nov 2025

Systemic inflammation impairs recovery from hookworm-associated anemia in a wild marine mammal host

in Comparative Immunology

Violetta Zaitseva
Nanami Arakawa
Carmon Co
Aranza Gomez-Camus
Diego Perez-Venegas
Felipe Montalva
Josefina Gutiérrez
Claudia Ulloa-Contreras
Ricardo Chihuailaf
Claudio Verdugo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659969

1,465 views

Review

Published on 10 Nov 2025

Unveiling the gut-liver axis: the behind-the-scenes “manipulator” of human immune function

in Comparative Immunology

Peizhe Li
Yu Wang
Yanan Dong
Xin Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638197

2,468 views
3 citations

Original Research

Published on 06 Nov 2025

Carotenoid-based immune response in sea cucumbers relies on newly identified coelomocytes—the carotenocytes

in Comparative Immunology

Noé Wambreuse
Estelle Bossiroy
Frank David
Céline Vanwinge
Laurence Fievez
Fabrice Bureau
Sylvain Gabriele
Tania Karasiewicz
Cyril Mascolo
Ruddy Wattiez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1668167

4,555 views

Original Research

Published on 04 Nov 2025

Dermal fibroblast cultures recapitulate differences between deermice and mice in their responses to a Toll-like receptor agonist

in Comparative Immunology

Jonathan V. Duong
Aqsa Motiwala
William J. Hotz
Landen Gozashti
Anthony D. Long
Alan G. Barbour

Frontiers in Immunology

doi 10.3389/fimmu.2025.1666789

2,226 views

Original Research

Published on 28 Oct 2025

Upregulated haptoglobin in classical monocytes serves as a diagnostic and immunological biomarker in myocardial infarction: a cross-sectional multi-omics study

in Comparative Immunology

Hongchen Xu
Huibin Pan
Chanjuan Mo
Xueqi Guo
Longfei Ji
Danfei Shi
Binyu Wang
Guodong Li
Yong Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707912

2,175 views

Original Research

Published on 22 Oct 2025

Study on the regulatory role of MINK1 gene in the activation of NLRP3 inflammasome in common carp (Cyprinus carpio L.)

in Comparative Immunology

Rongrong Liu
Keying Zhao
Yue Zhao
Guiwen Yang
Hua Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663527

1,161 views

Correction

Published on 21 Oct 2025

Correction: Mass cytometric analysis of circulating immune landscape in primary central nervous system lymphoma

in Comparative Immunology

Yuchen Wu
Liwei Lv
Jing Liu
Xuefei Sun
Chunji Gao
Shengjun Sun
Nan Ji
Wenjing Wang
Yuanbo Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1725923

842 views

Original Research

Published on 21 Oct 2025

Early allergen introduction overrides allergy predisposition in offspring of horses with Culicoides hypersensitivity

in Comparative Immunology

Elisabeth M. Simonin
Sigurbjorg Torsteinsdóttir
Vilhjálmur Svansson
Sigríður Björnsdóttir
Heather Freer
Justine Tarsillo
Bettina Wagner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654693

2,533 views

Original Research

Published on 17 Oct 2025

Marburg and Sudan viruses elicit divergent interferon responses and cytokine storm signaling in Egyptian rousette bat macrophages

in Comparative Immunology

Ivet A. Yordanova
Catherine E. Arnold
Nicolas Corrales
Jonathan C. Guito
Angelika Lander
Lay Teng Ang
Jonathan S. Towner
Joseph B. Prescott

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686343

2,883 views

Original Research

Published on 15 Oct 2025

Mass cytometric analysis of circulating immune landscape in primary central nervous system lymphoma

in Comparative Immunology

Yuchen Wu
Liwei Lv
Jing Liu
Xuefei Sun
Chunji Gao
Shengjun Sun
Nan Ji
Wenjing Wang
Yuanbo Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658015

2,407 views
1 citation

Original Research

Published on 15 Oct 2025

Comprehensive evaluation of individual and combined dietary carotenoids in Penaeus vannamei and response surface analysis for optimizing combinations

in Comparative Immunology

Yucai Xue
Bin Han
Yansong Xue
Ganfeng Yi
Meiqin Wu
Amina S Moss
Xuxiong Huang
Weilong Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1688761

2,118 views

Original Research

Published on 15 Oct 2025

The evolutionary history of IGKC in mammals reveals ancient duplications and remarkable divergence in lagomorphs

in Comparative Immunology

Ana Pinheiro
J. Ricardo Borges
João Pedro Marques
Pedro José Esteves

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686094

1,941 views

Original Research

Published on 15 Oct 2025

Mitochondrial dysfunction in PRRSV-2-infected macrophages

in Comparative Immunology

Thien-Phong Vu Manh
Alba Frias-De-Diego
Abigail Williams
John Byrne
Chaitawat Sirisereewan
Julie Hicks
Hsiao-Ching Liu
Elisa Crisci

Frontiers in Immunology

doi 10.3389/fimmu.2025.1670488

3,077 views
1 citation

Review

Published on 15 Oct 2025

Neutrophil and neutrophil extracellular traps in acute kidney injury: from mechanisms to treatments

in Comparative Immunology

Yifei Fu
Wenjuan Wang
Na Gong
Xumin Zheng
Xinru Guo
Kaiting Zhuang
Qiuxia Han
Zhe Feng
Xiangmei Chen
Guangyan Cai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1688207

4,135 views

Original Research

Published on 10 Oct 2025

Characterization of T-cell immune responses against Staphylococcus chromogenes naturally-induced subclinical mastitis in dairy cows

in Comparative Immunology

Chen Yu
Jie Wu
Sheng Zhang
Chunmei Ye
Guojun Wei
Zhangping Yang
Zhipeng Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679963

2,302 views

Original Research

Published on 08 Oct 2025

Genetic reinstatement of RIG-I in chickens reveals insights into avian immune evolution and influenza interaction

in Comparative Immunology

Hicham Sid
Theresa von Heyl
Sabrina Schleibinger
Romina Klinger
Leah Heymelot Nabel
Hanna Vikkula
Rodrigo Guabiraba
Vanaique Guillory
Ryan Scicluna
Mohanned Naif Alhussien

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680791

2,878 views
1 citation

Original Research

Published on 08 Oct 2025

A novel role for Hsc70–4 in blood cell differentiation in Drosophila

in Comparative Immunology

Bayan Kharrat
Erika Gábor
Péter Vilmos
Lauren M. Goins
Viktor Honti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641695

2,420 views
1 citation

Original Research

Published on 07 Oct 2025

Anti-inflammatory mechanism of total flavonoids from Polygala fallax Hemsl. based on network pharmacology, molecular docking, and experimental validation

in Comparative Immunology

Chunhong Liao
Hua Su
Fengzhen Li
Chenglong Wang
Sufang Yang
Zujie Qin
Ning Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690388

2,733 views

Original Research

Published on 06 Oct 2025

Differential perception of virulence factors of uropathogenic Escherichia coli at the level of chromatin dynamics of infected host cells

in Comparative Immunology

Krishnendu Mukherjee
Wiebke Aschenbach
Annika Hilger
Judith Saur
Ulrich Dobrindt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642683

2,515 views

Original Research

Published on 02 Oct 2025

Bulk and single-cell transcriptome profiling reveals the dynamic immune response in granulomatous amebic encephalitis caused by Balamuthia mandrillaris: a cohort study

in Comparative Immunology

Jingjia Zhang
Xinmiao Jia
Bin Yang
Ying Ge
Wei Jiang
Yang Cong
Huanwen Wu
Huifang Liu
Jingjing Tian
Yingchun Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677014

2,465 views

Original Research

Published on 01 Oct 2025

High-content stimulated Raman pathology imaging and transcriptomics reveal leukemia subtype-specific lipid metabolic heterogeneity

in Comparative Immunology

Xuelian Cheng
Jing Liu
Ming Chen
Haoyu Wang
Shuxu Dong
Yuan Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662281

2,324 views

Original Research

Published on 30 Sep 2025

Genomic characterization of the T-cell receptor loci in Ambystoma mexicanum

in Comparative Immunology

Diana L. Pacheco-Olvera
Stephanie Saint Remy-Hernández
E. Ernestina Godoy-Lozano
Juan Téllez-Sosa
Humberto Valdovinos-Torres
Everado Curiel-Quesada
Constantino López-Macías
Jesus Martínez-Barnetche

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656386

2,758 views
1 citation

Original Research

Published on 29 Sep 2025

Resveratrol suppresses OSCC invasion and migration by regulating macrophage polarization via Syk signaling pathway

in Comparative Immunology

Weibo Li
Ying Qi
Yafei Li
Lu Liu
Xiaodan Dong
Bo Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1660851

2,231 views

1,448 articles

articles

Different kinetics of humoral response against individual antigens in the ovine model of Toxoplasma gondii infection and its pathological association

Systemic inflammation impairs recovery from hookworm-associated anemia in a wild marine mammal host

Unveiling the gut-liver axis: the behind-the-scenes “manipulator” of human immune function

Carotenoid-based immune response in sea cucumbers relies on newly identified coelomocytes—the carotenocytes

Dermal fibroblast cultures recapitulate differences between deermice and mice in their responses to a Toll-like receptor agonist

Upregulated haptoglobin in classical monocytes serves as a diagnostic and immunological biomarker in myocardial infarction: a cross-sectional multi-omics study

Study on the regulatory role of MINK1 gene in the activation of NLRP3 inflammasome in common carp (Cyprinus carpio L.)

Correction: Mass cytometric analysis of circulating immune landscape in primary central nervous system lymphoma

Early allergen introduction overrides allergy predisposition in offspring of horses with Culicoides hypersensitivity

Marburg and Sudan viruses elicit divergent interferon responses and cytokine storm signaling in Egyptian rousette bat macrophages

Mass cytometric analysis of circulating immune landscape in primary central nervous system lymphoma

Comprehensive evaluation of individual and combined dietary carotenoids in Penaeus vannamei and response surface analysis for optimizing combinations

The evolutionary history of IGKC in mammals reveals ancient duplications and remarkable divergence in lagomorphs

Mitochondrial dysfunction in PRRSV-2-infected macrophages

Neutrophil and neutrophil extracellular traps in acute kidney injury: from mechanisms to treatments

Characterization of T-cell immune responses against Staphylococcus chromogenes naturally-induced subclinical mastitis in dairy cows

Genetic reinstatement of RIG-I in chickens reveals insights into avian immune evolution and influenza interaction

A novel role for Hsc70–4 in blood cell differentiation in Drosophila

Anti-inflammatory mechanism of total flavonoids from Polygala fallax Hemsl. based on network pharmacology, molecular docking, and experimental validation

Differential perception of virulence factors of uropathogenic Escherichia coli at the level of chromatin dynamics of infected host cells

Bulk and single-cell transcriptome profiling reveals the dynamic immune response in granulomatous amebic encephalitis caused by Balamuthia mandrillaris: a cohort study

High-content stimulated Raman pathology imaging and transcriptomics reveal leukemia subtype-specific lipid metabolic heterogeneity

Genomic characterization of the T-cell receptor loci in Ambystoma mexicanum

Resveratrol suppresses OSCC invasion and migration by regulating macrophage polarization via Syk signaling pathway