Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Original Research

Published on 17 Apr 2025

Concomitant autoimmunity and late cancers in adult-onset immunodeficiency due to neutralizing anti-IFN-γ autoantibodies

in Cytokines and Soluble Mediators in Immunity

Wan-Ting Tsai
Chih-Yun Cheng
Hsin-Yun Sun
Bei-Chia Guo
Ying-Chieh Chiang
Chiao-Feng Cheng
Yi-Hua Pan
Un-In Wu
Jann-Tay Wang
Wang-Huei Sheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526439

297 views

Original Research

Accepted on 16 Apr 2025

Evaluation of Humoral and Cellular Immune Responses in Healthcare Workers with Varying Levels of SARS-Cov-2 Exposure: Effects of CoronaVac Vaccination followed by Heterologous Booster

in Cytokines and Soluble Mediators in Immunity

Shayane Martins Rodrigues Gomes
Marcelo Ribeiro-Alves
Roberto Stefan de Almeida Ribeiro
Andréia Carolinne de Souza Brito
Vinícius da Cunha Lisboa
Samara Galdino de Azevedo
Jeane Nogueira
Leda dos Reis Castilho
Luís Cristóvão Sobrino Pôrto
Silvia Amaral Gonçalves Da-Silva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1576430

Editorial

Accepted on 16 Apr 2025

Editorial: The immunological events of macrophages in the course of sepsis

in Cytokines and Soluble Mediators in Immunity

Xu Li
Shiyun Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610868

Original Research

Accepted on 14 Apr 2025

Endogenous SLPI contributes to the regulation of inflammatory responses in peritoneal macrophages by modulating MMP-9 production

in Cytokines and Soluble Mediators in Immunity

Mariia Tyshchenko
Natalia Pocałuń
Patrycja Kwiecińska
Joanna Cichy
Mieszko Wilk
Ewa Oleszycka

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563845

143 views

Original Research

Accepted on 14 Apr 2025

TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT celldependent acute lung injury

in Cytokines and Soluble Mediators in Immunity

Ting Zhou
Ziyao Zhang
Yawen Zhan
Meiying Wang
Mi Wu
Xiufang Weng
Younian Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583235

Original Research

Published on 14 Apr 2025

Impact of alcohol consumption on outcomes and potential of immune biomarkers for postoperative complications in trauma patients

in Cytokines and Soluble Mediators in Immunity

Mohammad Majd Hammour
Yelda Anuk
Regina Breinbauer
Romina H. Aspera-Werz
Yuxuan Xin
Guanqiao Chen
Tina Histing
Sabrina Ehnert
Andreas K. Nüssler
Stefan Döbele

Frontiers in Immunology

doi 10.3389/fimmu.2025.1492288

286 views

Original Research

Published on 11 Apr 2025

Hematological and biochemical markers and cytokine levels in hospitalized psychiatric patients with COVID-19

in Cytokines and Soluble Mediators in Immunity

Huirong Dai
Chih-Jung Chang
Zishun Li
Farong Liu
Qiao Zhang
Yixuan Bai
Pan You

Frontiers in Immunology

doi 10.3389/fimmu.2025.1536117

390 views

Original Research

Published on 11 Apr 2025

LPS-induced extracellular AREG triggers macrophage pyroptosis through the EGFR/TLR4 signaling pathway

in Cytokines and Soluble Mediators in Immunity

Gang Yuan
Qudi Qiao
Aolin Jiang
Zehui Jiang
Haihua Luo
Lin Huang
Jieyan Wang
Yong Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549749

236 views

Original Research

Accepted on 10 Apr 2025

Developing an in vitro Osteochondral Micro-Physiological System for Modeling Cartilage-Bone Crosstalk in Arthritis

in Cytokines and Soluble Mediators in Immunity

Kyra Smith
Stephanie L. Fung
Hsin-Fang Wu
Irene Chiesa
Giovanni Vozzi
Carmelo De Maria
Riccardo Gottardi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1495613

Review

Accepted on 09 Apr 2025

The Effects of Interleukin-21 in the Biology of Transplant Rejection

in Cytokines and Soluble Mediators in Immunity

Xiandong Zeng
Yixiao Pan
Qiang Xia
Kang He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571828

Original Research

Published on 08 Apr 2025

High interleukin-35 expression is associated with the severity of rheumatic mitral stenosis

in Cytokines and Soluble Mediators in Immunity

Ping Wang
Yaxiong Li
Li Zhao
Bin Liu
Zhibin Cai
Peng Zhang
Peng Li
Xuezhen Gao
Yong Zhan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1537497

185 views

Original Research

Accepted on 03 Apr 2025

Apolipoprotein M expression modifies the sphingolipid landscape in murine blood and lymph

in Cytokines and Soluble Mediators in Immunity

Victoria A Blaho
Joshua T Minyard

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572959

107 views

Review

Published on 03 Apr 2025

Epigenetics of maternal-fetal interface immune microenvironment and placental related pregnancy complications

in Cytokines and Soluble Mediators in Immunity

Xueqin Ma
Xin Chen
Xuefeng Mu
Min Cao
Yan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549839

454 views

Original Research

Accepted on 31 Mar 2025

Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response

in Cytokines and Soluble Mediators in Immunity

Jorgo Lika
James A Votava
Rupsa Datta
Aleksandr M Kralovec
Frances M Smith
Anna Huttenlocher
Melissa C Skala
Jing Fan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572927

121 views

Mini Review

Published on 31 Mar 2025

The role of polysaccharides in immune regulation through gut microbiota: mechanisms and implications

in Cytokines and Soluble Mediators in Immunity

Ting Zhao
Congyue Wang
Yuhan Liu
Bo Li
Mingjia Shao
Wuyang Zhao
Chuang Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555414

600 views

Editorial

Published on 26 Mar 2025

Editorial: SOCS: regulation of the immune system at a whole new level

in Cytokines and Soluble Mediators in Immunity

Sandra E. Nicholson
Chulbul M. Ahmed
Karen Doggett
Daniela Marasco
Howard M. Johnson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588549

543 views