Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Original Research

Published on 11 Feb 2026

Integrative analysis of DNA methylation and inflammatory protein biomarkers in hypertension

in Cytokines and Soluble Mediators in Immunity

Min Zhu
Jin Zhang
Jing Ma
Xiaofeng Tang
Yan Wang
Dingliang Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1671540

156 views

Review

Published on 11 Feb 2026

Cytokines and related signaling pathways in traumatic brain injury

in Cytokines and Soluble Mediators in Immunity

Lihong Zhu
Siyun Huang
Weiqiang Chen
Kangsheng Li
Jiangtao Sheng

Frontiers in Immunology

doi 10.3389/fimmu.2026.1738589

264 views

Mini Review

Published on 09 Feb 2026

IL-35, IL-37, and IL-38 in acute pancreatitis: proposed immunopathogenic mechanisms and therapeutic potential

in Cytokines and Soluble Mediators in Immunity

Hailong Yan
Xingbo Dang
Gongliang Du
Longyang Ma
Wei Dai
Shisan Bao
Xiujuan Huang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1728737

273 views

Mini Review

Accepted on 06 Feb 2026

Interleukins in Community-Acquired Pneumonia: From Biomarkers to Precision Medicine

in Cytokines and Soluble Mediators in Immunity

Xiaoying Zhang
Tongshuo Zhang
Ruihui Geng
Luqing Wei
Hui Liu
Hanyu Shi

Frontiers in Immunology

248 views

Original Research

Accepted on 06 Feb 2026

PBMC Transcriptomic Signatures Reflect Immune Dynamics and Disease Activity in Psoriatic Arthritis

in Cytokines and Soluble Mediators in Immunity

Ruihong Hou
Yang Liu
Dengfeng Xue
Ruonan Wu
Ke Xu
Liyun Zhang

Frontiers in Immunology

Original Research

Published on 06 Feb 2026

Association of SARS-CoV-2 infection with long-lasting increase in circulating IL-32 levels

in Cytokines and Soluble Mediators in Immunity

Lorenzo Miano
Elena Sinopoli
Alessandro Cherubini
Chiara Suffritti
Serena Pelusi
Fatima Rahmeh
Giuseppe Enzo Lamorte
Flora Peyvandi
Francesco Blasi
Giacomo Grasselli

Frontiers in Immunology

doi 10.3389/fimmu.2026.1739258

1,155 views

Original Research

Published on 06 Feb 2026

Oncostatin M upregulates CD73 via the MAPK pathway in keratinocytes to promote an adenosine-dependent anti-inflammatory response in psoriasis

in Cytokines and Soluble Mediators in Immunity

Caterina Giraulo
Giacomo De Palma
Paola Plaitano
Roberta Esposito
Elva Morretta
Maria Chiara Monti
Christa E. Müller
Carla Cicala
Silvana Morello

Frontiers in Immunology

doi 10.3389/fimmu.2026.1698290

476 views

Original Research

Published on 06 Feb 2026

Glycosaminoglycan binding to soluble CX3CL1 impacts monocyte migration in vitro

in Cytokines and Soluble Mediators in Immunity

Maria Ennemoser
Paula Peinsipp
Tihana Novak
Clara Matteini
Dorian Tauschmann
Tanja Gerlza
Andreas J. Kungl

Frontiers in Immunology

doi 10.3389/fimmu.2026.1747705

863 views

Mini Review

Published on 04 Feb 2026

CX3CL1/CX3CR1 axis in liver disease: context-dependent roles and balance

in Cytokines and Soluble Mediators in Immunity

Jing Liu
Zhen Guo
Xin Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2026.1763348

360 views

Original Research

Published on 04 Feb 2026

Persistent neutrophil activation despite count normalization suggests immune dysregulation in exertional heat stroke

in Cytokines and Soluble Mediators in Immunity

Yue Wang
Siya Xu
Zhongzhi Tang
Jie Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718617

562 views

Review

Accepted on 03 Feb 2026

Health Risk Analysis of Micro-and Nanoplastic Exposure via the Microbiota-Gut-Brain Axis

in Cytokines and Soluble Mediators in Immunity

Yuhua Chi
Xuan Wang
Haoming Yu
Jihong Li
胜宇韩

Frontiers in Immunology

109 views

Original Research

Published on 03 Feb 2026

Homoeriodictyol, targeting the bitter taste receptor TAS2R14, lowers the secretion of pro-inflammatory chemokines upon treatment with SARS-CoV-2 peptide pools in human peripheral blood mononuclear cells

in Cytokines and Soluble Mediators in Immunity

Barbara Danzer
Gaby Andersen
Kristin Kahlenberg
Veronika Somoza

Frontiers in Immunology

doi 10.3389/fimmu.2026.1771794

569 views

Original Research

Accepted on 02 Feb 2026

The Diagnostic Accuracy of CC Chemokine Ligand 23 for Kawasaki Disease

in Cytokines and Soluble Mediators in Immunity

Weiping Xun
Lifen Rao
Jinwen Liao
Xin Guo
Qiuming Miu
Yinbi Zheng

Frontiers in Immunology

Review

Accepted on 02 Feb 2026

Unraveling Fibrinogen-like Protein 1's Role in Immune Regulation

in Cytokines and Soluble Mediators in Immunity

Fengjia Xi
Rongzeng Liu

Frontiers in Immunology

Original Research

Published on 02 Feb 2026

Interleukin-15 and innate effector cells as predictors of outcome in allogeneic hematopoietic cell transplantation

in Cytokines and Soluble Mediators in Immunity

Marie Warny
Sisse Rye Ostrowski
Søren Lykke Petersen
Lone Smidstrup Friis
Brian Thomas Kornblit
Niels Smedegaard Andersen
Ida Schjødt
Margit Hørup Larsen
Janne Amstrup Møller
Eva Kannik Haastrup

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649313

597 views

Original Research

Published on 30 Jan 2026

Vitamin D3 mediates amelioration of ulcerative colitis via the TRPV1-MAPK signaling pathway

in Cytokines and Soluble Mediators in Immunity

Keke Zhao
Jian Li
Yersen Asai
Longxiang Zhang
Ziying Hu
Hongliang Gao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1727932

366 views

Original Research

Published on 30 Jan 2026

Role of PBAF and Mediator kinase module in the RELA-dependent activation of CXCL1–3 inflammation genes of the NF-kB pathway

in Cytokines and Soluble Mediators in Immunity

Alexey V. Feoktistov
Anton A. Grigel
Ivan A. Zolin
Darya M. Yurkina
Anna V. Tvorogova
Asya M. Azieva
Sofia G. Georgieva
Nataliya V. Soshnikova

Frontiers in Immunology

doi 10.3389/fimmu.2026.1702928

954 views

Original Research

Published on 30 Jan 2026

Hepatocyte growth factor as a driver of synovial inflammation and therapeutic resistance in rheumatoid arthritis

in Cytokines and Soluble Mediators in Immunity

Quang Minh Dang
Ryu Watanabe
Takeshi Iwasaki
Ryuhei Ishihara
Keiichiro Kadoba
Koichi Murata
Masao Tanaka
Hiromu Ito
Thanh Duc Tran
Sang Quang Tran Nguyen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1718591

779 views

Original Research

Published on 29 Jan 2026

Interferon levels and interferon-stimulated gene expression identify patient subsets with distinct clinical and immunological characteristics in systemic lupus erythematosus

in Cytokines and Soluble Mediators in Immunity

Ridi Khatri
Amrutha Jose
Anjali Rajadhyaksha
Kalpana Mehta
Nilesh Nolkha
Seema Kini
Milind Nadkar
Pooja Jaiswal
Pratiksha Pawar
Swapnal Pawaskar

Frontiers in Immunology

doi 10.3389/fimmu.2026.1757895

621 views

Original Research

Published on 29 Jan 2026

Cytokines in patients with Posner-Schlossman syndrome

in Cytokines and Soluble Mediators in Immunity

Yu Liu
Shengjie Li
Xiangmei Kong
Qilian Sheng
Zhujian Wang
Wenjun Cao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1739027

442 views

Review

Published on 28 Jan 2026

Role of IL-32 in RA pathology and potential as a drug target

in Cytokines and Soluble Mediators in Immunity

Hongliang Zhang
Qingyuan Chen
Hui Yu
Mingzi Zhu
Xiaoqing Zhang
Xin Fu
Songquan Wu
Guangli Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1696081

361 views

Original Research

Accepted on 27 Jan 2026

Miniaturized IL-2/anti-IL-2 immunocytokines selectively activate and support the in vivo persistence of regulatory T cells

in Cytokines and Soluble Mediators in Immunity

Charina S. Fabilane
Jakub Tomala
Paul M. Zdinak
Bailey T. Chalmers
A Carson Stephenson
Emily Ariail
Ella C. Teeley
Alok Vishnu Joglekar
Jamie Berta Spangler

Frontiers in Immunology

201 views

Original Research

Accepted on 27 Jan 2026

Cytokine profiles and laboratory parameters as indicators to distinguish children with PFAPA and bacterial infection

in Cytokines and Soluble Mediators in Immunity

Xiaona Zhu
Zhi Yang
Yanyan Huang
Ying Luo
Yang Jun
Tingyan He

Frontiers in Immunology

Review

Published on 27 Jan 2026

Type I interferons in bacterial diseases: myeloid cells at the crossroads of protection and pathology

in Cytokines and Soluble Mediators in Immunity

Irina Lyadova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1717370

643 views

1,315 articles

articles

Integrative analysis of DNA methylation and inflammatory protein biomarkers in hypertension

Cytokines and related signaling pathways in traumatic brain injury

IL-35, IL-37, and IL-38 in acute pancreatitis: proposed immunopathogenic mechanisms and therapeutic potential

Interleukins in Community-Acquired Pneumonia: From Biomarkers to Precision Medicine

PBMC Transcriptomic Signatures Reflect Immune Dynamics and Disease Activity in Psoriatic Arthritis

Association of SARS-CoV-2 infection with long-lasting increase in circulating IL-32 levels

Oncostatin M upregulates CD73 via the MAPK pathway in keratinocytes to promote an adenosine-dependent anti-inflammatory response in psoriasis

Glycosaminoglycan binding to soluble CX3CL1 impacts monocyte migration in vitro

CX3CL1/CX3CR1 axis in liver disease: context-dependent roles and balance

Persistent neutrophil activation despite count normalization suggests immune dysregulation in exertional heat stroke

Health Risk Analysis of Micro-and Nanoplastic Exposure via the Microbiota-Gut-Brain Axis

Homoeriodictyol, targeting the bitter taste receptor TAS2R14, lowers the secretion of pro-inflammatory chemokines upon treatment with SARS-CoV-2 peptide pools in human peripheral blood mononuclear cells

The Diagnostic Accuracy of CC Chemokine Ligand 23 for Kawasaki Disease

Unraveling Fibrinogen-like Protein 1's Role in Immune Regulation

Interleukin-15 and innate effector cells as predictors of outcome in allogeneic hematopoietic cell transplantation

Vitamin D3 mediates amelioration of ulcerative colitis via the TRPV1-MAPK signaling pathway

Role of PBAF and Mediator kinase module in the RELA-dependent activation of CXCL1–3 inflammation genes of the NF-kB pathway

Hepatocyte growth factor as a driver of synovial inflammation and therapeutic resistance in rheumatoid arthritis

Interferon levels and interferon-stimulated gene expression identify patient subsets with distinct clinical and immunological characteristics in systemic lupus erythematosus

Cytokines in patients with Posner-Schlossman syndrome

Role of IL-32 in RA pathology and potential as a drug target

Miniaturized IL-2/anti-IL-2 immunocytokines selectively activate and support the in vivo persistence of regulatory T cells

Cytokine profiles and laboratory parameters as indicators to distinguish children with PFAPA and bacterial infection

Type I interferons in bacterial diseases: myeloid cells at the crossroads of protection and pathology