Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Original Research

Published on 12 Jun 2025

Contribution of CARD9 signaling to wound healing in skin promoted by topical administration of heat-killed Enterococcus faecalis strain KH2 and the involvement of Dectin-2

in Cytokines and Soluble Mediators in Immunity

Shiho Kurosaka
Hiromasa Tanno
Minako Hirose
Wakana Kamada
Rena Takayashiki
Ikue Sone
Yuki Sato
Takumi Watanabe
Shinyo Ishi
Miki Shoji

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550934

779 views

Original Research

Published on 11 Jun 2025

IL-17A drives a fibroblast-neutrophil-NET axis to exacerbate immunopathology in the lung with diffuse alveolar damage

in Cytokines and Soluble Mediators in Immunity

Duo Su
Lu Li
Hao Xie
Lingli Ai
Yuqing Wang
Bo Yang
Dongsheng Zhou
Lingfei Hu
Huiying Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574246

759 views

Original Research

Published on 11 Jun 2025

Human saliva exerts strong type-dependent effects on adenovirus infectivity

in Cytokines and Soluble Mediators in Immunity

Erwan Sallard
Wenli Zhang
Nikita Chilakamarri
Setareh Farzanehkari
Inga Marte Charlott Seuthe
Anja Ehrhardt
Malik Aydin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579896

638 views

Review

Published on 04 Jun 2025

Soluble SARS-CoV-2 Spike glycoprotein: considering some potential pathogenic effects

in Cytokines and Soluble Mediators in Immunity

Bruno Azzarone
Nadine Landolina
Francesca Romana Mariotti
Lorenzo Moretta
Enrico Maggi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616106

1,563 views

Original Research

Published on 03 Jun 2025

High-fat diet-induced adipose tissue-resident macrophages, T cells, and dendritic cells modulate chronic inflammation and adipogenesis during obesity

in Cytokines and Soluble Mediators in Immunity

Mousumi Mandal
Md Abdullah Al Mamun
Ahmed Rakib
Udai P. Singh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524544

1,946 views

Review

Published on 02 Jun 2025

Role of interleukin-16 in human diseases: a novel potential therapeutic target

in Cytokines and Soluble Mediators in Immunity

Timothy B. Niewold
Julia S. Lehman
Iva Gunnarsson
Alexander Meves
Vilija Oke

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524026

1,378 views

Original Research

Published on 30 May 2025

Cytokine concentration in peripheral blood of patients with childhood obesity

in Cytokines and Soluble Mediators in Immunity

Jia Mai
Min Wang
Ying Guo
Ling Yang
HongJian Xie
Lan Mei
ZiYao Zhu
XiaoJuan Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606375

705 views

Original Research

Published on 30 May 2025

Markers of T cell activation and exhaustion in plasma are associated with persistent symptoms up to 18 months following mild SARS-CoV-2 infection

in Cytokines and Soluble Mediators in Immunity

Thor Ueland
Rebecca Jane Cox
Annika E. Michelsen
Elisabeth Berg Fjelltveit
Kari Otterdal
Tuva Dahl
Fan Zhou
Rebecca Elyanow
Pål Aukrust
Bjørn Blomberg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578208

1,303 views

Original Research

Published on 30 May 2025

Association between pan-immune-inflammation value and Serum Klotho levels: a cross-sectional analysis of renal function mediation

in Cytokines and Soluble Mediators in Immunity

Mingjie Liu
Xuan Zhou
Han Xu
Yan Wang
Yuting Duan
Xiangru Guo
Bai Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567367

979 views

Original Research

Published on 28 May 2025

Autophagy crosstalk with the immune microenvironment in chronic myeloid leukemia and serves as a biomarker for diagnosis and progression

in Cytokines and Soluble Mediators in Immunity

Fangmin Zhong
Fangyi Yao
Jing Liu
Qun Fang
Xiajing Yu
Bo Huang
Xiaozhong Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570903

1,179 views

Original Research

Published on 27 May 2025

Endogenous SLPI contributes to the regulation of inflammatory responses in peritoneal macrophages by modulating MMP-9 production

in Cytokines and Soluble Mediators in Immunity

Mariia Tyshchenko
Natalia Pocałuń
Patrycja Kwiecińska
Joanna Cichy
Mieszko M. Wilk
Ewa Oleszycka

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563845

1,343 views

Original Research

Published on 26 May 2025

Developing an in vitro osteochondral micro-physiological system for modeling cartilage-bone crosstalk in arthritis

in Cytokines and Soluble Mediators in Immunity

Kyra W. Y. Smith
Stephanie L. Fung
Hsin-Fang Wu
Irene Chiesa
Giovanni Vozzi
Carmelo De Maria
Riccardo Gottardi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1495613

1,877 views

Original Research

Published on 23 May 2025

TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT cell-dependent acute lung injury

in Cytokines and Soluble Mediators in Immunity

Ting Zhou
Ziyao Zhang
Yawen Zhan
Meiying Wang
Mi Wu
Xiufang Weng
Younian Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583235

1,693 views

General Commentary

Published on 20 May 2025

Commentary: Guselkumab binding to CD64+ IL-23–producing myeloid cells enhances potency for neutralizing IL-23 signaling

in Cytokines and Soluble Mediators in Immunity

Giulia Valdiserra
Clelia Di Salvo
Matteo Fornai
Luca Antonioli

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604337

1,181 views

Original Research

Published on 08 May 2025

Evaluation of humoral and cellular immune responses in healthcare workers with varying levels of SARS-CoV-2 exposure: effects of CoronaVac vaccination followed by heterologous booster

in Cytokines and Soluble Mediators in Immunity

Shayane Martins Rodrigues Gomes
Marcelo Ribeiro-Alves
Roberto Stefan de Almeida Ribeiro
Andréia Carolinne de Souza Brito
Vinicius da Cunha Lisboa
Samara Galdino de Azevedo
Jeane de Souza Nogueira
Leda dos Reis Castilho
Luís Cristóvão Sobrino Pôrto
Silvia Amaral Gonçalves da Silva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1576430

1,635 views

Original Research

Published on 06 May 2025

Characterization and correlation analysis of oral NET markers and inflammatory factor levels in patients after orthodontic treatment: a pilot study

in Cytokines and Soluble Mediators in Immunity

Qian Liu
Axian Wang
Donghui Guo
Houzhuo Luo
Shishu Fang
Zhixin Song
Yi Wen
Fang Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1490637

855 views