Frontiers in Immunology

Original Research

Published on 02 Oct 2025

Premature renal epithelial cell senescence promoted by LXN/Rps3/p53 signaling pathway activation increases calcium oxalate crystal deposition by altering macrophage polarization

in Inflammation

Maolin Chu
Suna Jiang
Jiawei Xue
Wenjing Li
Guanhua Jing
Hongying Li
Juan Zhang
Wanhai Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658989

312 views

Review

Published on 02 Oct 2025

Role of novel protein acylation modifications in sepsis

in Inflammation

Jing Wang
Aifeng He
Lin Song
Wei Jiang
Lu Xu
Ruiqiang Zheng
Jiangquan Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657194

221 views

Original Research

Published on 01 Oct 2025

Tuina therapy alleviates knee osteoarthritis by modulating PI3K/AKT/mTOR-mediated autophagy: an integrated machine learning and in vivo rat study

in Inflammation

Zhen Wang
Chi Zhao
Mengmeng Li
Lili Zhang
Jieyao Diao
Yiming Wu
Tao Yang
Mingwei Shi
Yang Lei
Yu Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635818

523 views

Review

Published on 01 Oct 2025

Cell-free mitochondrial DNA as a pro-inflammatory agent in blood circulation: mechanisms, therapeutic implications, and clinical challenges in immune dysregulation

in Inflammation

Yangyang Zhao
Chunlei Wu
Xiaoxue Liang
Mengjiao Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640748

970 views

Mini Review

Published on 01 Oct 2025

Platelets as central hubs of inflammation

in Inflammation

Yan Bo
Fei Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683553

461 views

Original Research

Published on 01 Oct 2025

Severe COVID-19 induces prolonged elevation of the acute-phase protein pentraxin 3

in Inflammation

Bernhard Kratzer
Robert B. Stieger
Seyma Durmus
Doris Trapin
Pia Gattinger
Paul Ettel
Al Nasar Ahmed Sehgal
Kristina Borochova
Yulia Dorofeeva
Inna Tulaeva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672485

1,680 views

Mini Review

Accepted on 30 Sep 2025

Innate immune-inflammatory signaling milieu in myeloid leukemia & aging-associated clonal hematopoiesis pathologies

in Inflammation

Satyaki Bhowmik
Anwesha Bose
Amitava Sengupta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1660709

Systematic Review

Accepted on 30 Sep 2025

Mind-body therapies for pro-inflammatory cytokines in patients with depression: Findings from a systematic review of randomized controlled trials

in Inflammation

Zhengyang Mei
Shi Luo
Chenyi Cai
Lam Chifong
Tingfeng Wang
Haichang Jia
Longjiang Chen
Ranran He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677872

110 views

Original Research

Accepted on 30 Sep 2025

Narrowband Ultraviolet B Radiation Attenuates Nucleus Pulposus Pyroptosis to Ameliorate Intervertebral Disc Degeneration by Activating NRF2/KEAP1 Antioxidant Pathway

in Inflammation

Helou Zhang
Xinyun Tang
Huiqing Zhou
Chengcong Zhou
Zhiguo Zhang
Shuchao Shen
Xu Liang Fang
Jiazhe Du
Shenghua Cheng
Jinjie Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663674

Original Research

Published on 30 Sep 2025

FKBP5-CCL5 interaction promotes neuroinflammation and neuronal apoptosis in ischemic stroke by regulating the MAPK pathway and enhancing NET formation

in Inflammation

Zhongchen Li
Tengkun Yin
Hongyang Guo
Zhenxing Liu
Peijian Wang
Chao Liu
Qingbo Wang
Meng Zhang
Yilei Xiao
Jiyue Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609989

441 views

Original Research

Accepted on 29 Sep 2025

The inflammatory architecture reflects the effects of pharmacological and genetic interventions on resolution of TLR2-mediated inflammation

in Inflammation

Clara Kramer
Sandra Pierre
Nicole Zander
Anja Kolbinger
Blerina Aliraj
Andreas Weigert
Klaus Scholich

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633348

330 views

Mini Review

Accepted on 29 Sep 2025

Functional Heterogeneity of Mast Cells in Cutaneous Inflammation: Implications for Precision Medicine

in Inflammation

Surui A
Dugarmaa Ulzii
Enkhtur Yadamsuren
Jihai Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680574

325 views

Original Research

Accepted on 29 Sep 2025

Integrating Bioinformatics and Molecular Experiments to Reveal the Critical Role of the Cellular Energy Metabolism-Related Marker PLA2G1B in COPD Epithelial Cells

in Inflammation

Jun Shi
Zihan Wang
Yafei Rao
Dan-Yang Li
Ying Luo
Yue Zhang
Yuqiang Pei
Xiaoyan Gai
Yongchang Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1666195

272 views

Review

Accepted on 29 Sep 2025

THERAPEUTIC CHALLENGES IN CENTRAL NERVOUS SYSTEM VIRAL INFECTIONS: ADVANCING MESENCHYMAL STEM CELL-BASED STRATEGIES FOR TREATING NEUROINFLAMMATION AND PROMOTING TISSUE REPAIR

in Inflammation

Javier Carbone-Schellman
Javiera Fontecilla-Escobar
Nicolás Sales-Salinas
William Chaparro
Alfredo Enrique Molina-Berríos
María Celeste Ruete
Pablo A. González
Mayra A. Machuca
Ma. Cecilia Opazo
Marcelo Ezquer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677433

210 views

Brief Research Report

Accepted on 29 Sep 2025

Sulphur compounds navigate redox processes, leukotriene synthesis and ω-hydroxylation of leukotriene B4 at neutrophil interaction with bacteria Salmonella typhimurium: the way to manipulate neutrophil swarming

in Inflammation

Ekaterina Golenkina
Sofia V. Navarnova
Galina M. Viryasova
Svetlana Galkina
Tatjana V. Gaponova
Yulia M. Romanova
Galina F. Sud’ina

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606408

122 views

Original Research

Accepted on 29 Sep 2025

ATF3 prevents retinal ganglion cell apoptosis and mitigates microglia-mediated neuroinflammation in retinal ischemia–reperfusion injury

in Inflammation

Ningzhi Zhang
Tian Tian
Zhiyi Wang
Xuejun He
Wenye Cao
Wenxi Zhang
Yiqiao Xing
Ning Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671204