Frontiers in Immunology

Review

Published on 23 Jul 2025

Mechanistic and therapeutic insights into the function of different cell death modalities in rheumatoid arthritis: emphasis on the crosstalk with non-coding RNAs

in Inflammation

Jianting Wen
Jian Liu
Lei Wan
Fanfan Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620209

3,040 views
1 citation

Original Research

Published on 23 Jul 2025

Multi-organ pathology in a small porcine model of cytokine storm syndrome characteristics

in Inflammation

Jiaqian Jin
Linxiao Fan
Richai Chen
Xuanhao Lin
Sainan Zhang
Mengfei Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618665

1,372 views

Original Research

Published on 22 Jul 2025

Disease control and disease activity in hereditary angioedema: two sides of the same coin?

in Inflammation

Behzad Heibati
Jack Borle
Bruce Ritchie
Adil Adatia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631448

2,518 views

Original Research

Published on 22 Jul 2025

Regulation of hepatic Sirt1 expression and lipid metabolism through TNF receptor signaling

in Inflammation

Ian N. Hines
Samuel B. Stafford
Blair U. Bradford
Michael D. Wheeler

Frontiers in Immunology

doi 10.3389/fimmu.2025.1627433

2,363 views
1 citation

Mini Review

Published on 22 Jul 2025

Ferroptosis: a key driver and therapeutic target in the pathogenesis of acute respiratory distress syndrome

in Inflammation

Mingjun Yao
Jinfeng Liao
Zheng Liu
Wei Zhao
Siyuan Song
Xiaobo Huang
Yi Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567980

4,276 views
1 citation

Brief Research Report

Published on 21 Jul 2025

Macrophage transfer promotes intestinal mucosal healing by encouraging transit-amplifying cell expansion in mice

in Inflammation

Dong su Kang
Young min Song
Yeon Ji Park
Hyeon Jong Jeong
Jung Joo Hong
Seung Hyeok Seok
Yi Rang Na

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555695

3,315 views
1 citation

Original Research

Published on 21 Jul 2025

TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury

in Inflammation

Yunsheng Zhang
Yulian Zhang
Hanhan Dang
Chuanpeng Zhang
Kun He
Xu Yang
Zixi Wang
Li Zhang
Yanbing Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636917

3,752 views

Original Research

Published on 21 Jul 2025

Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints

in Inflammation

Rosanne D. Reitsema
Seta Kurt
Ignacio Rangel
Hans Hjelmqvist
Mats Dreifaldt
Allan Sirsjö
Ashok Kumar Kumawat

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568431

1,845 views

Review

Published on 18 Jul 2025

Multidimensional mechanisms and therapies underlying gastroesophageal reflux disease: focus on immunity, signaling pathways, and the microbiota-gut-brain axis

in Inflammation

Jiajing Zheng
Lin Tao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629944

5,008 views
2 citations

Original Research

Published on 18 Jul 2025

C-reactive protein induced T cell activation is an indirect monocyte-dependent mechanism involving the CD80/CD28 pathway

in Inflammation

Julia Thomé
Julia Limmer
Teresa Z. Brose
Johannes Zeller
Nina Chevalier
Anna-Lena Schäfer
Laura Schneider
Maike Lind
Thierry Christmann
Marie Dreck

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622865

2,275 views
3 citations

Editorial

Published on 18 Jul 2025

Editorial: Community series in pathogenetic mechanism and therapeutic target for inflammation in autoimmune disease, volume II

in Inflammation

Jia Li
Minrui Liang
Hai-Feng Pan
Jian Gao
Yuekang Xu
Liangjing Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645760

1,465 views

Original Research

Published on 17 Jul 2025

Vitamin D ameliorates prediabetic cardiac injure via modulation of the ErbB4/ferroptosis signaling axis

in Inflammation

Yufan Miao
Yujing Zhang
Luoya Zhang
Hao Chen
Lulu Tang
Wenjie Li
Chenxi Gu
Lili Lang
Xing Li
Hanlu Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626295

2,692 views

Original Research

Published on 17 Jul 2025

Exosome circ-CBLB promotes M1 macrophage polarization in rheumatoid arthritis through the TLR3/TRAF3 signaling axis

in Inflammation

Mengyu Zhang
Lei Wan
Xiaojun Zhang
Siyu Wang
Feng Li
Dawei Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1627389

3,478 views
1 citation

Review

Published on 17 Jul 2025

From laboratory to clinic: a precise treatment strategy of mesenchymal stem cells-derived exosomes pretreated by simulating disease microenvironment

in Inflammation

Hailian Ye
Qi He
Fang Qi
Guangchao Xu
Mulan Qahar
Chenliang Deng
Zairong Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609288

2,910 views
1 citation

Review

Published on 17 Jul 2025

Research progress of PYK2 in digestive system diseases

in Inflammation

Yiyao Duan
Mingzhu Xie
Hui Wang
Sijing Chen
Jun Hu
Xujia Chen
Hong Ping Jia
Ningyan Zhang
Ling Peng
Xiang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1614589

1,688 views

Original Research

Published on 16 Jul 2025

Frailty Index-laboratory and lymphocyte subset patterns in predicting 28-day mortality among elderly sepsis patients: a multicenter observational cohort study

in Inflammation

Dongkai Li
Jiatong Hou
Zhan Shi
Xiao Li
Jiahui Zhang
Guoyu Zhao
Xianli Lei
Yawen Xie
Yuefu Wang
Hao Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624655

2,206 views

Original Research

Published on 16 Jul 2025

Identification of CTSC-driven progression in ESCC by single-cell sequencing and experimental validation

in Inflammation

Xin Sui
Yongxu Jia
Jing Li
Jiayao Xu
Wenjia Wang
Yanru Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585139

2,518 views
1 citation

Review

Published on 16 Jul 2025

Ferroptosis and bone health: bridging the gap between mechanisms and therapy

in Inflammation

Renyan Xiao
Zhongyu Han
Peng Jia
Pei Li
Meng Gong
Yijin Cai
Lina Pang
Xiangyin Ye
Song Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634516

2,378 views
3 citations

Original Research

Published on 16 Jul 2025

Identification and validation of biomarkers, construction of diagnostic models, and investigation of immunological infiltration characteristics for idiopathic frozen shoulder

in Inflammation

Han-tao Jiang
Li-ping Shen
Meng-Qi Pang
Min-jiao Wu
Jiang Li
Wei-jie Gong
Gang Jin
Rang-teng Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1559422

1,974 views

Original Research

Published on 16 Jul 2025

Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients

in Inflammation

Roberta Belli
Anna Dattolo
Francesca Sampogna
Emanuela Gubinelli
Daniela Lulli
Gaia Moretta
Emanuele Scala
Luca Sanna
Matteo Megna
Maria Vittoria Cannizzaro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607312

3,665 views
3 citations

Correction

Published on 15 Jul 2025

Correction: Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfusion injury

in Inflammation

Qiao Tang
Jiatao Xie
Yifei Wang
Chong Dong
Qian Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642215

1,413 views
1 citation

Editorial

Published on 14 Jul 2025

Editorial: Modulation of pro-inflammatory signaling by interferons

in Inflammation

René Huber
Korbinian Brand
Kyung-Hyun Park-Min

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657424

1,065 views

Original Research

Published on 11 Jul 2025

Trichinella spiralis-derived extracellular vesicles induce regulatory T cells and reduce airway allergy in mice

in Inflammation

Sofija Glamočlija
Ljiljana Sabljić
Anna Schmid
Nataša Radulović
Alisa Gruden-Movsesijan
Saša Vasilev
Aleksandra Inić-Kanada
Ursula Wiedermann
Irma Schabussova
Maja Kosanović

Frontiers in Immunology

doi 10.3389/fimmu.2025.1637569

2,993 views

Original Research

Published on 10 Jul 2025

PET imaging of tissue reactions in the implanted cochlea: results of a pilot study

in Inflammation

Philipp Deutsch
Jens P. Bankstahl
Martin Mamach
Michael Willmann
Frank M. Bengel
Thomas Lenarz
Georg Berding
Verena Scheper
Jana Schwieger

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601742

1,805 views

5,616 articles

articles

Mechanistic and therapeutic insights into the function of different cell death modalities in rheumatoid arthritis: emphasis on the crosstalk with non-coding RNAs

Multi-organ pathology in a small porcine model of cytokine storm syndrome characteristics

Disease control and disease activity in hereditary angioedema: two sides of the same coin?

Regulation of hepatic Sirt1 expression and lipid metabolism through TNF receptor signaling

Ferroptosis: a key driver and therapeutic target in the pathogenesis of acute respiratory distress syndrome

Macrophage transfer promotes intestinal mucosal healing by encouraging transit-amplifying cell expansion in mice

TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury

Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints

Multidimensional mechanisms and therapies underlying gastroesophageal reflux disease: focus on immunity, signaling pathways, and the microbiota-gut-brain axis

C-reactive protein induced T cell activation is an indirect monocyte-dependent mechanism involving the CD80/CD28 pathway

Editorial: Community series in pathogenetic mechanism and therapeutic target for inflammation in autoimmune disease, volume II

Vitamin D ameliorates prediabetic cardiac injure via modulation of the ErbB4/ferroptosis signaling axis

Exosome circ-CBLB promotes M1 macrophage polarization in rheumatoid arthritis through the TLR3/TRAF3 signaling axis

From laboratory to clinic: a precise treatment strategy of mesenchymal stem cells-derived exosomes pretreated by simulating disease microenvironment

Research progress of PYK2 in digestive system diseases

Frailty Index-laboratory and lymphocyte subset patterns in predicting 28-day mortality among elderly sepsis patients: a multicenter observational cohort study

Identification of CTSC-driven progression in ESCC by single-cell sequencing and experimental validation

Ferroptosis and bone health: bridging the gap between mechanisms and therapy

Identification and validation of biomarkers, construction of diagnostic models, and investigation of immunological infiltration characteristics for idiopathic frozen shoulder

Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients

Correction: Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfusion injury

Editorial: Modulation of pro-inflammatory signaling by interferons

Trichinella spiralis-derived extracellular vesicles induce regulatory T cells and reduce airway allergy in mice

PET imaging of tissue reactions in the implanted cochlea: results of a pilot study