Frontiers in Immunology

Original Research

Published on 28 May 2025

Baseline type 2 biomarker levels and clinical remission predictors in children with asthma

in Inflammation

Mengmeng Chen
Congcong Li
Qiuyan Yang
Huijie Zhang
Yanli Zhang
Na Wang
Jingcheng Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1492644

3,765 views
2 citations

Original Research

Published on 28 May 2025

Protein carbamylation in atherosclerotic plaques correlates with uremia and disease progression, localizing predominantly to foam cells

in Inflammation

Valeria Saar-Kovrov
Aleksandra Pawlowska
Adrien Guillot
Marion J. J. Gijbels
Judith C. Sluimer
Lieve Temmerman
Pieter Goossens
Barend M. E. Mees
Frank Tacke
Vera Jankowski

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532250

2,660 views

Original Research

Published on 28 May 2025

Exploring the role of neutrophils in inflammatory pain hypersensitivity via single-cell transcriptome profiling

in Inflammation

Kai Ding
Xing Liu
Bin Zeng
Songyu Liu
Lu Zhang
Bo Li
Jinyi Zhou
Xiaosan Su
Jun Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1552993

3,129 views
1 citation

Original Research

Published on 28 May 2025

Identification of mitophagy-related biomarkers in severe acute pancreatitis: integration of WGCNA, machine learning algorithms and scRNA-seq

in Inflammation

Xiaozhou Xie
Zheng Wang
Haoyu Zhang
Jiongdi Lu
Feng Cao
Fei Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1594085

5,266 views
1 citation

Review

Published on 27 May 2025

Lymphatic-immune interactions in the musculoskeletal system

in Inflammation

Hanyu Liu
Lu Liu
Yuheng Zhang
Qi Tian
Zhangfan Ding
Junyu Chen
Anjali P. Kusumbe

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578847

5,384 views
4 citations

Original Research

Published on 27 May 2025

The HL-60 clone 15 cell line as a model for leukocyte migration–possibilities and limitations

in Inflammation

Lena Griesbaum
Christopher Weusthof
Thorben Sauer
Timo Gemoll
Gregor Weirich
Ludger Klimek
Julie Petry
Ali Bashiri Dezfouli
Maria Shoykhet
Barbara Wollenberg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1515993

3,979 views

Original Research

Published on 27 May 2025

mTOR promotes the formation and growth of tertiary lymphoid tissues in the kidney

in Inflammation

Daniel J. Atwood
Zhibin He
Makoto Miyazaki
Katharina Hopp
Alkesh Jani
Seth B. Furgeson
Sarah Faubel
Charles L. Edelstein

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527817

2,169 views

Original Research

Published on 26 May 2025

Identification of Grb2 protein as a potential mediator of macrophage activation in acute pancreatitis based on bioinformatics and experimental verification

in Inflammation

Qinhao Shen
Shuai Wang
Keyan Wu
Liuhui Wang
Weijuan Gong
Guotao Lu
Weiwei Chen
Chenchen Yuan
Bo Tu
Wei Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575880

3,333 views
1 citation

Review

Published on 26 May 2025

Review of the mechanism of infection induced cerebral small vessel disease

in Inflammation

Jiamei Song
Yiqin Wang
Zhaoxia Xie
Jiayi Wei
Jue Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1594891

3,891 views

Review

Published on 23 May 2025

The role of fibroblast-neutrophil crosstalk in the pathogenesis of inflammatory diseases: a multi-tissue perspective

in Inflammation

Chen Cai
Lanxi Guan
Chenhao Wang
Runjie Hu
Lingling Ou
Qianzhou Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588667

7,038 views
5 citations

Original Research

Published on 23 May 2025

Changes in immune cell signatures during early infection reflect decoupling of capillary perfusion and glycocalyx dimensions

in Inflammation

Anna Hunkemöller
Timo Wirth
Alexandros Rovas
Hermann Pavenstädt
Luisa Klotz
Philipp Kümpers

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589959

2,863 views

Review

Published on 23 May 2025

The pivotal role of inflammatory factors in glaucoma: a systematic review

in Inflammation

Bin Lin
Dongkan Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1577200

4,382 views
10 citations

Original Research

Published on 22 May 2025

Epithelial-to-mesenchymal transition is an active process in the large airways of patients with asthma-COPD overlap and partially abrogated by inhaled corticosteroid treatment: a bronchoscopy endobronchial biopsy study

in Inflammation

Surajit Dey
Wenying Lu
Prabuddha S. Pathinayake
Maddison Waters
Greg Haug
Josie Larby
Heinrich C. Weber
Peter A. B. Wark
Mathew Suji Eapen
Sukhwinder Singh Sohal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1531279

3,813 views
1 citation

Original Research

Published on 22 May 2025

Macrophage pyroptosis mediates hyperoxia-induced inflammatory lung injury in neonates

in Inflammation

Zikun Tu
Haiyan Guo
Yajing Gao
Wenfeng Xiao
Xueru Xie
Hongmiao Yu
Qiuyan Liang
Yufeng Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1546986

4,014 views
3 citations

Original Research

Published on 22 May 2025

Distinct proteomic signatures in Ethiopians predict acute and long-term sequelae of COVID-19

in Inflammation

Dawit Wolday
Abrha G. Gebrehiwot
An Nguyen Le Minh
Muhammed Ahmed Rameto
Saro Abdella
Atsbeha Gebreegziabxier
Wondwossen Amogne
Tobias F. Rinke de Wit
Messay Hailu
Getachew Tollera

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575135

3,577 views
2 citations

Editorial

Published on 22 May 2025

Editorial: Differential activation of cell death pathways in macrophages as a result of adaptation to divergent microenvironment

in Inflammation

Krzysztof Guzik
Philippe Saas
David Masson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623587

1,454 views

Original Research

Published on 22 May 2025

Thrombospondin-1 mitigates osteoarthritis progression by inhibiting mechanical stress-induced chondrocyte ferroptosis via the integrin/YAP pathway

in Inflammation

Shaoyi Wang
Xiaocong Zhou
Fujian Zhang
Haoxin Zhai
Yuanqiang Zhang
Yongyuan Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1577234

4,930 views
2 citations

Mini Review

Published on 21 May 2025

Ferroptosis in idiopathic pulmonary fibrosis: mechanisms, impact, and therapeutic opportunities

in Inflammation

Mingjun Yao
Zheng Liu
Wei Zhao
Siyuan Song
Xiaobo Huang
Yi Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567994

9,961 views
9 citations

Clinical Trial

Published on 21 May 2025

Lanadelumab for prevention of attacks of non-histaminergic normal C1 inhibitor angioedema: results from the randomized, double-blind CASPIAN Study and CASPIAN open-label extension

in Inflammation

Marc A. Riedl
Petra Staubach
Henriette Farkas
Andrea Zanichelli
Hong Ren
Christina Nurse
Irmgard Andresen
Salomé Juethner
Ming Yu
Jingmei Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1502325

6,315 views
1 citation

Original Research

Published on 20 May 2025

Single-cell RNA sequencing identifies two fibroblast subtypes and a Trem2+ macrophage subtype as the possible specific cellular targets in abdominal aortic aneurysms

in Inflammation

Zhili Liu
Xiaojun Song
Ben Wang
Rong Zeng
Liqiang Cui
Yuehong Zheng
Wei Ye

Frontiers in Immunology

doi 10.3389/fimmu.2025.1551308

3,334 views
3 citations

Mini Review

Published on 20 May 2025

The ontogeny of synovial tissue macrophages

in Inflammation

Joseph Hutton
Wenrui Sun
Tetsuo Hasegawa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1603473

2,775 views

Original Research

Published on 20 May 2025

Single-cell transcriptomics reveals cellular dynamics and chemokine CXCL2-mediated smooth muscle cell proliferation in arterial repair

in Inflammation

Xingxiao Huang
Yan Ping
Qiuli Sun
Mingjun Yu
Chao Yang
Xiao Liu
Long Wang
Jinyu Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591557

2,920 views
1 citation

Mini Review

Published on 20 May 2025

AI-driven multi-omics profiling of sepsis immunity in the digestive system

in Inflammation

Yuan Gao
Hong Chen
Ruolan Wu
ZuJun Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590526

4,935 views
6 citations

Original Research

Published on 20 May 2025

Aqueous humor cytokines levels and illuminated microcatheter-assisted circumferential trabeculotomy outcome in open-angle glaucoma patients: a 24-month prospective study

in Inflammation

Tingyi Wu
Qianqian Ji
Yanfeng Liao
Xiaoyu Zhao
Ying Hong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575909

1,836 views

5,618 articles

articles

Baseline type 2 biomarker levels and clinical remission predictors in children with asthma

Protein carbamylation in atherosclerotic plaques correlates with uremia and disease progression, localizing predominantly to foam cells

Exploring the role of neutrophils in inflammatory pain hypersensitivity via single-cell transcriptome profiling

Identification of mitophagy-related biomarkers in severe acute pancreatitis: integration of WGCNA, machine learning algorithms and scRNA-seq

Lymphatic-immune interactions in the musculoskeletal system

The HL-60 clone 15 cell line as a model for leukocyte migration–possibilities and limitations

mTOR promotes the formation and growth of tertiary lymphoid tissues in the kidney

Identification of Grb2 protein as a potential mediator of macrophage activation in acute pancreatitis based on bioinformatics and experimental verification

Review of the mechanism of infection induced cerebral small vessel disease

The role of fibroblast-neutrophil crosstalk in the pathogenesis of inflammatory diseases: a multi-tissue perspective

Changes in immune cell signatures during early infection reflect decoupling of capillary perfusion and glycocalyx dimensions

The pivotal role of inflammatory factors in glaucoma: a systematic review

Epithelial-to-mesenchymal transition is an active process in the large airways of patients with asthma-COPD overlap and partially abrogated by inhaled corticosteroid treatment: a bronchoscopy endobronchial biopsy study

Macrophage pyroptosis mediates hyperoxia-induced inflammatory lung injury in neonates

Distinct proteomic signatures in Ethiopians predict acute and long-term sequelae of COVID-19

Editorial: Differential activation of cell death pathways in macrophages as a result of adaptation to divergent microenvironment

Thrombospondin-1 mitigates osteoarthritis progression by inhibiting mechanical stress-induced chondrocyte ferroptosis via the integrin/YAP pathway

Ferroptosis in idiopathic pulmonary fibrosis: mechanisms, impact, and therapeutic opportunities

Lanadelumab for prevention of attacks of non-histaminergic normal C1 inhibitor angioedema: results from the randomized, double-blind CASPIAN Study and CASPIAN open-label extension

Single-cell RNA sequencing identifies two fibroblast subtypes and a Trem2+ macrophage subtype as the possible specific cellular targets in abdominal aortic aneurysms

The ontogeny of synovial tissue macrophages

Single-cell transcriptomics reveals cellular dynamics and chemokine CXCL2-mediated smooth muscle cell proliferation in arterial repair

AI-driven multi-omics profiling of sepsis immunity in the digestive system

Aqueous humor cytokines levels and illuminated microcatheter-assisted circumferential trabeculotomy outcome in open-angle glaucoma patients: a 24-month prospective study