Frontiers in Immunology

Original Research

Accepted on 03 Feb 2026

The exosomal miR-26b-3p derived from Crohn's Disease-associated mesenteric adipose tissue induces M1 macrophage polarization and exacerbates ileocolonic anastomosis inflammation via the p38-MAPK signaling pathway

in Inflammation

Enhao Wu
Wenwei Qian
Xi Zhang
Lili Gu
Zhen Guo
Zeqian Yu
Yi Li
Weiming Zhu

Frontiers in Immunology

Original Research

Accepted on 03 Feb 2026

Tianhuang Formula Attenuates Cardiomyocyte Pyroptosis in Myocardial Infarction by Suppressing Oxidative Stress and the cGAS–STING–NLRP3 Axis

in Inflammation

Mei ling Yan
Yifan Chen
Guida Cai
Xi Zhang
Kun-Ping Li
Duosheng Luo
Lexun Wang
Xianglu Rong
Jiao Guo

Frontiers in Immunology

107 views

Original Research

Accepted on 03 Feb 2026

Integrating Bioinformatic Prediction and the "Gut Microbiota-Inflammation-Skin Axis" to Decipher the Mechanisms of Quercetin (from Evodia rutaecarpa) in Diabetic Wound Healing

in Inflammation

Zhixuan Huang
Jian Liu
Xu Zheng
Xinrong Geng
Jinlong Tan
Yangwen Ai
Hui Li
Dongyue Zhou

Frontiers in Immunology

Original Research

Accepted on 03 Feb 2026

Integrated Transcriptomic and Functional Analyses Reveal that NOX2 Inhibition Rewires the Inflammatory Landscape of Macrophages

in Inflammation

Iswarya Muthukumarasamy
Sharleen M. Buel
Jennifer M Hurley
Jonathan S Dordick

Frontiers in Immunology

Review

Published on 03 Feb 2026

Macrophage polarisation under immune regulation as a therapeutic target for tendon-bone healing: multifactorial regulation and mechanistic insights

in Inflammation

Wanxue Wang
Liang Zhang
Yu Jiang
Dexi Cui
Kehao Hou
Shengquan Ren
Xia Zhao
Yingze Zhang
Ning Yu
Chao Qi

Frontiers in Immunology

doi 10.3389/fimmu.2026.1737444

569 views

Editorial

Published on 03 Feb 2026

Editorial: Mechanisms of cell death in acute liver diseases and the pathobiology of sterile inflammation: The double-edged sword problem

in Inflammation

Juan C. Cutrin
Carmen Peralta Uroz

Frontiers in Immunology

doi 10.3389/fimmu.2026.1792869

420 views

Original Research

Published on 03 Feb 2026

Genetic susceptibility to PM2.5 exposure and transcriptional responses in pediatric asthma: insights from single-cell transcriptomics

in Inflammation

Jelte Kelchtermans
Huiqi Qu
Cuiping Hou
Frank Mentch
Sharon A. McGrath-Morrow
Hakon Hakonarson

Frontiers in Immunology

doi 10.3389/fimmu.2026.1644537

723 views

Review

Published on 03 Feb 2026

The impact of obesity-related systemic inflammation on the efficacy, toxicity, and biomarkers of immune checkpoint inhibitors in lung cancer: from mechanisms to clinical management

in Inflammation

Yewei Cai
Tianxing Ni

Frontiers in Immunology

doi 10.3389/fimmu.2026.1757711

477 views

Correction

Published on 03 Feb 2026

Correction: Safety and efficacy of nemolizumab for patients with pruritus: a systematic review and meta-regression analysis of randomized controlled trial

in Inflammation

Junqin Liang
Fengxia Hu
Maoli Dan
Yingbing Sang
Kailibinuer Abulikemu
Qian Wang
Yongzhen Hong
Xiaojing Kang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1773876

268 views

Correction

Published on 03 Feb 2026

Correction: Integrated single cell and bulk RNA-Seq analysis revealed immunomodulatory effects of Ulinastatin in sepsis: a multicenter cohort study

in Inflammation

Lin Chen
Senjun Jin
Min Yang
Chunmei Gui
Yingpu Yuan
Guangtao Dong
Weizhong Zeng
Jing Zeng
Guoxin Hu
Lujun Qiao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1793340

303 views

Review

Published on 03 Feb 2026

Neutrophil extracellular traps and microglia/macrophages interactions in stroke: from thromboinflammation to immunotherapy

in Inflammation

Nurittin Ardic
Rasit Dinc

Frontiers in Immunology

doi 10.3389/fimmu.2026.1752471

611 views

Review

Accepted on 02 Feb 2026

Microvesicles in thermal burn injury Evidence for Microvesicle Particles and Platelet-activating Factor as Effectors for Systemic Effects of Thermal Burn Injury

in Inflammation

Akhil V Parackal
Richard C Fox
Aadil Umerani
Youngjun Park
R Michael Johnson
Wenfeng Zhang
Zheng Xu
Alison Smith
Craig A Rohan
Jeffrey B Travers

Frontiers in Immunology

215 views

Review

Accepted on 02 Feb 2026

Crosstalk of Mitochondrial Dysfunction and Macrophage Polarization in Sepsis

in Inflammation

Jingxiao Zhang
Min Zhang
Fuxi Ji
Li Zhang

Frontiers in Immunology

121 views

Original Research

Accepted on 02 Feb 2026

Identification of FTO as a key m6A demethylase linking immune dysregulation to sepsis pathogenesis

in Inflammation

Yi Jiao
Rui Lian
Jian Wei Zhang
Nan Gao
Qishun Geng
Tian Tian Deng
Ran Zhao Wang
Tingting Deng
Cheng Xiao
Guoqiang Zhang

Frontiers in Immunology

Correction

Published on 02 Feb 2026

Correction: Anti-inflammatory effects of natural polysaccharides: molecular mechanisms and nanotherapeutic applications

in Inflammation

Frontiers Production Office

Frontiers in Immunology

doi 10.3389/fimmu.2026.1797602

315 views

Editorial

Published on 02 Feb 2026

Editorial: The role of nod-like receptor (NLR) family of proteins in inflammation

in Inflammation

Atika Dhar
Rishi Kumar Jaiswal
Hasan Zaki
Samithamby Jeyaseelan

Frontiers in Immunology

doi 10.3389/fimmu.2026.1793019

541 views

Review

Published on 02 Feb 2026

Neuroinflammatory regulatory role of microglia in optic nerve injury: from pathological mechanisms to therapeutic targets

in Inflammation

Miaoran Gao
Jian Zhou
Nannan Shi
Xiaoling Yan
Lina Liang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1742677

546 views

Review

Published on 02 Feb 2026

Cardiac resident macrophages: the emerging role in arrhythmogenesis

in Inflammation

Jiaqian Zhao
Jun Liu
Ying Zou
Jianhong Li
Ming Lei
Xiaoqiu Tan
Tangting Chen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1753815

559 views

Original Research

Published on 02 Feb 2026

Artificial neural network-based analysis of ferroptosis-associated molecular subtypes and immunological profiles in abdominal aortic aneurysm

in Inflammation

Maohua Li
Shasha Xiao
Qi Qin
Keyun Fu
Lunchang Wang
Xin Li
Jiehua Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1721069

450 views

Review

Accepted on 31 Jan 2026

Stem Cell-Based Therapies for Silicosis: Mechanisms, Sources, Clinical Translation, and Emerging Strategies

in Inflammation

Xinru Feng
Bo Xiao
Lixia Hou
Bingxi Zhang
Lincha Tian
Biwen Mo
Dong Yao

Frontiers in Immunology

256 views

Original Research

Accepted on 31 Jan 2026

CLIC6 and ANLN: Novel Exosome-Related Prognostic Markers and Therapeutic Targets in Lung Adenocarcinoma

in Inflammation

Yajun Miao
Tao Li
Rong Li
Yufei Liu

Frontiers in Immunology

152 views

Original Research

Accepted on 30 Jan 2026

Glycine Receptors in Circulating White Blood Cells Regulated by Neuroinflammation

in Inflammation

VIKRAM THAKUR
Yathip Mindy Chokpapone
Rakshak Mishra
Osarenoma Evbuomwan
Lizbeth Lopez
Camila Guerrero
Alexandra Chavez
Ingrid Carrizales
Brianna J. Rodriguez Chavez
Jonathan Lavezo

Frontiers in Immunology

177 views

Review

Published on 30 Jan 2026

Molecular mechanisms of skeletal muscle fibrosis and potential targeted therapeutic strategies

in Inflammation

Jiahuan Gong
Jingxuan Xu
Jitai Zhang
Yuntian Shen
Hualin Sun
Bingqian Chen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1714238

924 views

Original Research

Published on 30 Jan 2026

Meningeal lymphatic vessel dysfunction exacerbates brain injury in CVST mice via endoplasmic reticulum and oxidative stress pathways

in Inflammation

Jianbin Ying
Jun Li
Xianqun Wu
Xuanjie Chen
Hao Zhang
Liangfeng Wei
Junjie Jing
Shousen Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1745066

457 views