Frontiers in Immunology

Original Research

Published on 30 Jan 2026

Immunomodulatory properties of human dental pulp stromal cells: the role of IL-6/JAK/STAT3 pathway and PD-L1

in Inflammation

Rosanna Di Tinco
Alessandra Pisciotta
Giulia Bertani
Giulia Orlandi
Laura Bertoni
Elisa Pignatti
Martina Bonacini
Alessandro Rossi
Anke J. Roelofs
Stefania Croci

Frontiers in Immunology

doi 10.3389/fimmu.2026.1713704

800 views

Original Research

Published on 30 Jan 2026

Decoupling of maternal and neonatal inflammatory levels at the maternal-fetal interface: evidence from a population-based proteomic study

in Inflammation

Floriana Milazzo
Frederieke Gigase
Anna Suleri
Bushra Amreen
Darwin D’Souza
Seunghee Kim-Schulze
Veerle Bergink
Lot de Witte
Corina Lesseur
Anna-Sophie Rommel

Frontiers in Immunology

doi 10.3389/fimmu.2026.1715880

467 views

Original Research

Published on 29 Jan 2026

Electroacupuncture alleviates pain by activating the MD2/TLR4/NF-κB pathway in the ST36 acupoint

in Inflammation

Jiangjiang Fu
Gangchen Cheng
Zhongxi Lyu
Zezhi Fan
Feiyang Li
Zhifang Xu
Bo Chen
Yongming Guo
Yuhan Liu
Hui Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626755

878 views

Case Report

Published on 29 Jan 2026

Favorable coronary outcomes following IL-6 blockade with tocilizumab in IVIG-resistant kawasaki disease: a case series

in Inflammation

Jing Zheng
Yu Xu
Yan Pu
Jingyue Liu
Zhilang Cao
Yajun Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1729717

464 views

Original Research

Published on 29 Jan 2026

Enhanced CHI3L1 promotes macrophage activation in persistent inflammatory events of ulcerative interstitial cystitis

in Inflammation

Wei Zhang
Yize Guo
Jiawen Wang
Xiaodong Liu
Ting Xie
Yao Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1716297

495 views

Original Research

Published on 29 Jan 2026

Disturbed regulation of immunothrombosis in cerebral ischemia associated with SARS-CoV-2 infection

in Inflammation

Richard Plem
Nicole de Buhr
Rabea Imker
Silke Akhdar
Marita Meurer
Christine S. Falk
Johanna Ernst
Maria M. Gabriel
Jana Keil
Verena Kopfnagel

Frontiers in Immunology

doi 10.3389/fimmu.2026.1662418

794 views

Original Research

Published on 29 Jan 2026

Xinfeng capsule improves hyperinflammation-associated hypercoagulability and self-perception in osteoarthritis by regulating KLF4 through METTL14-mediated m6A modification of lncRNA MEG3

in Inflammation

Mingyu He
Jian Liu
Yanqiu Sun
Yanyan Fang
Fanfan Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1749727

404 views

Original Research

Published on 29 Jan 2026

Dahuang gancao dandelion decoction regulates intestinal flora and inhibits NF-κB/ARA signaling pathway to alleviate ulcerative colitis

in Inflammation

Xieraili Malajiang
Wan er Shen
Alimu Aersilan
Mengzi Liu
Yuan Liang
Shengyi Wang
Saifuding Abula
Adelijiang Wusiman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1735021

928 views

Editorial

Published on 29 Jan 2026

Editorial: Genetic and immunological insights into angioedema without wheals

in Inflammation

Matija Rijavec
Maurizio Margaglione
Anastasios E. Germenis

Frontiers in Immunology

doi 10.3389/fimmu.2026.1787741

561 views

Original Research

Accepted on 28 Jan 2026

Nerandomilast attenuates idiopathic inflammatory myopathy-associated interstitial lung disease via inhibiting proliferation and differentiation of B cells

in Inflammation

Yuming Liu
Yayue Hu
rigeleng Se
Zhongyi Yang
Xueze Liu
Jiayang Yu
Huihui Li
Songtao Gu
Weitao Yang
Cheng Yang

Frontiers in Immunology

317 views

Original Research

Published on 28 Jan 2026

Coagulation-related genes COL3A1 and MMP1 influence the development of osteoarthritis and the surrounding immunological environment

in Inflammation

Liangkun Huang
Xuezhong Wang
Zijie Pei
Ze Zhang
Fengpo Sun
Liangyuan Wen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1759281

637 views

Review

Published on 28 Jan 2026

Decoding the lncRNA-miRNA-mRNA network in sepsis-induced lung injury: from pathogenesis to extracellular vesicle-based therapy

in Inflammation

Yating Wei
Weiye Gong
Yuhua Wei
Xiaohong Jiang
Chaoqian Li
Rongzong Ye

Frontiers in Immunology

doi 10.3389/fimmu.2026.1701440

799 views

Original Research

Published on 28 Jan 2026

Apigenin ameliorates postoperative inflammation and accelerates wound healing in a rat model of perianal abscess by targeting the JAK1/STAT3 pathway in macrophages

in Inflammation

Ruixue Dai
Liangliang Cao
Jiahui Ren
Jingru Liu
Kexin Zhu
Peidong Chen
Weifeng Yao
Xuelong Zhao
Beihua Bao
Li Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1726917

738 views

Correction

Published on 28 Jan 2026

Correction: Pathological neutrophil extracellular traps hinder postoperative anal fistula wound healing and are attenuated by Zuoqing granule via suppression of the Nox4 pathway

in Inflammation

Xiaoli Fang
Heng Deng
Ming Li
Xiang Gao
Chunrong He
Hui Liu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1792671

459 views

Review

Published on 28 Jan 2026

Reactive sulfur species as emerging immunomodulators: mechanistic insights and therapeutic prospects

in Inflammation

Youbang Chen
Ruiying Ji
Yixing Wu
Xiang Li
Hui Zhang
Chun-tao Yang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1736794

809 views

Original Research

Published on 28 Jan 2026

The stem of Schisandra chinensis and Schisandrin B alleviated DNCB-induced atopic dermatitis in mice by inhibiting the NF-κB pathway

in Inflammation

Cai Ye
Yijie Liu
Yue Li
Zan Li
Liyuan Sui
Jiwen Cui
Zihao Jiang
Jinlian Li
Jianjun Song
Jiguang Liu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1725312

782 views

Original Research

Accepted on 27 Jan 2026

The potential role of mesenchymal stem cells enhanced with melatonin in renal damage induced experimentally by cecal ligation and puncture in rats

in Inflammation

Amina F. Hussein
Manal Elkhadragy
Rasha S. Elbeltagy
Ahmed Esmat Abdel Moneim
Mohga S. Abdalla

Frontiers in Immunology

243 views

Original Research

Accepted on 27 Jan 2026

Single-cell sequencing reveals reversible glial remodeling in the visual cortex during visual deprivation and recovery

in Inflammation

Xiaoqi Gong
Jiaojiao Feng
Zhe Xu
Yunxiao Xie
Yibo Han
Jing Li
Guodong Tang
Yuxi Liu
Xiaoyun Dong
Shuhan Li

Frontiers in Immunology

230 views

Original Research

Published on 27 Jan 2026

Identification of key genes associated with muscle atrophy after spinal cord injury and experimental verification in rats

in Inflammation

Xiang Wang
Yimin Gao
Jianzhong Huo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673367

620 views

Original Research

Published on 27 Jan 2026

Microglial histone H3K18 crotonylation promotes STAT1 expression and induces cognitive deficit in Alzheimer disease

in Inflammation

Ying Weng
Ting He
Mengzhu Li
Qiuzhi Zhou
Jiazhao Xie
Linyu Wei
Xin Wang
Jian-Zhi Wang
Maolin Zhong
Shihong Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1744375

899 views

Original Research

Published on 27 Jan 2026

KRTCAP2 accelerates malignant progression through modulating tumor cell function and M2 macrophage infiltration in glioma

in Inflammation

Chunmei Zhao
Yijie Sheng
Jianfei Huang
Xudong Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1727168

407 views

Original Research

Published on 27 Jan 2026

Role of cytokine levels in pathogen classification and prognosis of pediatric septic shock

in Inflammation

Guangyan Du
Haixin Huang
Ruichen Zhang
Chengjun Liu
Yueqiang Fu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1714948

494 views

Systematic Review

Published on 27 Jan 2026

The role of CD36 in immune function: bridging innate and adaptive responses

in Inflammation

Xiang Zhang
Ling-jie Luo
Yan-wei Wu
Liang Chen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1728509

425 views

Original Research

Published on 27 Jan 2026

Isoimperatorin alleviates fungal keratitis by regulating NF-κB pathway and macrophage immune response

in Inflammation

Shiqi Song
Huirong Xu
Mengzhu Liu
Qiang Xu
Ling Wang
Fenglei Wang
Xiaomei Wan
Xiaoyan Sun
Chengye Che

Frontiers in Immunology

doi 10.3389/fimmu.2026.1676397

565 views

5,801 articles

articles

Immunomodulatory properties of human dental pulp stromal cells: the role of IL-6/JAK/STAT3 pathway and PD-L1

Decoupling of maternal and neonatal inflammatory levels at the maternal-fetal interface: evidence from a population-based proteomic study

Electroacupuncture alleviates pain by activating the MD2/TLR4/NF-κB pathway in the ST36 acupoint

Favorable coronary outcomes following IL-6 blockade with tocilizumab in IVIG-resistant kawasaki disease: a case series

Enhanced CHI3L1 promotes macrophage activation in persistent inflammatory events of ulcerative interstitial cystitis

Disturbed regulation of immunothrombosis in cerebral ischemia associated with SARS-CoV-2 infection

Xinfeng capsule improves hyperinflammation-associated hypercoagulability and self-perception in osteoarthritis by regulating KLF4 through METTL14-mediated m6A modification of lncRNA MEG3

Dahuang gancao dandelion decoction regulates intestinal flora and inhibits NF-κB/ARA signaling pathway to alleviate ulcerative colitis

Editorial: Genetic and immunological insights into angioedema without wheals

Nerandomilast attenuates idiopathic inflammatory myopathy-associated interstitial lung disease via inhibiting proliferation and differentiation of B cells

Coagulation-related genes COL3A1 and MMP1 influence the development of osteoarthritis and the surrounding immunological environment

Decoding the lncRNA-miRNA-mRNA network in sepsis-induced lung injury: from pathogenesis to extracellular vesicle-based therapy

Apigenin ameliorates postoperative inflammation and accelerates wound healing in a rat model of perianal abscess by targeting the JAK1/STAT3 pathway in macrophages

Correction: Pathological neutrophil extracellular traps hinder postoperative anal fistula wound healing and are attenuated by Zuoqing granule via suppression of the Nox4 pathway

Reactive sulfur species as emerging immunomodulators: mechanistic insights and therapeutic prospects

The stem of Schisandra chinensis and Schisandrin B alleviated DNCB-induced atopic dermatitis in mice by inhibiting the NF-κB pathway

The potential role of mesenchymal stem cells enhanced with melatonin in renal damage induced experimentally by cecal ligation and puncture in rats

Single-cell sequencing reveals reversible glial remodeling in the visual cortex during visual deprivation and recovery

Identification of key genes associated with muscle atrophy after spinal cord injury and experimental verification in rats

Microglial histone H3K18 crotonylation promotes STAT1 expression and induces cognitive deficit in Alzheimer disease

KRTCAP2 accelerates malignant progression through modulating tumor cell function and M2 macrophage infiltration in glioma

Role of cytokine levels in pathogen classification and prognosis of pediatric septic shock

The role of CD36 in immune function: bridging innate and adaptive responses

Isoimperatorin alleviates fungal keratitis by regulating NF-κB pathway and macrophage immune response