Frontiers in Immunology | Microbial Immunology

Original Research

Published on 05 Mar 2025

Immune mediators as plasma biomarkers for identifying household contacts and classifying clinical forms and leprosy reactions

in Microbial Immunology

Jairo Campos Carvalho
Marcelo Antônio Pascoal-Xavier
Marcelo Grossi Araújo
Júlia Pereira Martins
Andrea Teixeira-Carvalho
Matheus de Souza Gomes
Laurence Rodrigues Amaral
Vanessa Peruhype-Magalhães
Jordana Grazziela Alves Coelho-dos-Reis
Olindo Assis Martins-Filho

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513060

2,153 views

Review

Published on 04 Mar 2025

Advancements in the investigation of gut microbiota-based strategies for stroke prevention and treatment

in Microbial Immunology

Min Wang
Yan Liu
Li Zhong
Fang Wu
Jinjin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1533343

6,971 views
6 citations

Review

Published on 03 Mar 2025

Post-stroke depression: exploring gut microbiota-mediated barrier dysfunction through immune regulation

in Microbial Immunology

Jia Jiang
Haihua Xie
Sihui Cao
Xuan Xu
Jingying Zhou
Qianyan Liu
Changsong Ding
Mi Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547365

8,477 views
7 citations

Original Research

Published on 03 Mar 2025

Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing

in Microbial Immunology

Tzu-Hsuan Chang
Yamel Cardona Gloria
Margareta J. Hellmann
Timmy Richardo
Carsten Leo Greve
Didier Le Roy
Thierry Roger
Francesca Bork
Stefanie Bugl
Johanna Jakob

Frontiers in Immunology

doi 10.3389/fimmu.2025.1497174

4,566 views
4 citations

Original Research

Published on 28 Feb 2025

Unveiling the immunological landscape of disseminated tuberculosis: a single-cell transcriptome perspective

in Microbial Immunology

Zhen Gong
Hongxiang Xu
Qiao Zhang
Guirong Wang
Lin Fan
Zilu Wang
Lichao Fan
Chang Liu
Yanhong Yu
Zhou Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527592

5,234 views
2 citations

Original Research

Published on 21 Feb 2025

Mycobacterium tuberculosis infection may increase the degrees of malignancy in lung adenocarcinoma

in Microbial Immunology

Shanshan Li
Mengru Feng
Fenghua Wang
Dongxu Liu
Mingyan Li
Jinlong Dai
Yan Yang
Yinghui Chai
Wen Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1537520

4,728 views
4 citations

Brief Research Report

Published on 20 Feb 2025

Case Report: First report of Legionella micdadei pneumonia and organizing pneumonia in a patient with myelodysplastic and Sweet syndromes

in Microbial Immunology

Yingying Chen
Sicong Liang
Ye Lu
Xiangyu Zhou
Rui Zheng
Yu Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1510948

2,783 views
1 citation

Original Research

Published on 19 Feb 2025

Association of systemic inflammation response index with latent tuberculosis infection and all-cause mortality: a cohort study from NHANES 2011-2012

in Microbial Immunology

Lin Wang
Yi Kuang
Yan Zeng
Zhihui Wan
Sha Yang
Renliang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538132

5,910 views
5 citations

Original Research

Published on 18 Feb 2025

Chaihushugan powder regulates the gut microbiota to alleviate mitochondrial oxidative stress in the gastric tissues of rats with functional dyspepsia

in Microbial Immunology

Xuejiao Liu
Keming Yang
Yuebo Jia
Yeliya Yeertai
Chenheng Wu
Xiangxiang Wang
Qingling Jia
Zhijian Gu
Jun Cong
Jianghong Ling

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549554

4,569 views
4 citations

Original Research

Published on 17 Feb 2025

Caspase-11 and NLRP3 exacerbate systemic Klebsiella infection through reducing mitochondrial ROS production

in Microbial Immunology

Yuqi Zhou
Zhuodong Chai
Ankit Pandeya
Ling Yang
Yan Zhang
Guoying Zhang
Congqing Wu
Zhenyu Li
Yinan Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1516120

4,273 views
5 citations

Original Research

Published on 14 Feb 2025

Patchoulene epoxide mitigates colitis and hepatic damage induced by dextran sulfate sodium by regulating the colonic microbiota and purine metabolism

in Microbial Immunology

Liping Chen
Lili Xie
Lifen Wang
Xueli Zhan
Zhenjian Zhuo
Susu Jiang
Lei Miao
Xinxin Zhang
Weiming Zheng
Tzu-Ming Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1509114

3,465 views
4 citations

Review

Published on 14 Feb 2025

Big lessons from the little Akkermansia muciniphila in hepatocellular carcinoma

in Microbial Immunology

Yanguang Yang
Xinli Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524563

8,029 views
5 citations

Review

Published on 10 Feb 2025

Implications of intratumoral microbiota in tumor metastasis: a special perspective of microorganisms in tumorigenesis and clinical therapeutics

in Microbial Immunology

Lei Zhang
Xichu Duan
Yanhua Zhao
Dejiu Zhang
Yuan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526589

4,645 views
5 citations

Review

Published on 07 Feb 2025

The role of short-chain fatty acid in metabolic syndrome and its complications: focusing on immunity and inflammation

in Microbial Immunology

Wenqian Yu
Siyuan Sun
Yutong Yan
Hong Zhou
Ziyi Liu
Qiang Fu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519925

7,876 views
31 citations

Review

Published on 06 Feb 2025

Characteristics, pathogenic and therapeutic role of gut microbiota in immunoglobulin A nephropathy

in Microbial Immunology

Kaijin Yao
Lingqian Zheng
Wenmin Chen
Yina Xie
Chunling Liao
Tianbiao Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1438683

6,800 views
3 citations

Review

Published on 06 Feb 2025

The importance of inflammatory biomarkers in detecting and managing latent tuberculosis infection

in Microbial Immunology

Harinisri Gunasekaran
Uma Devi Ranganathan
Ramalingam Bethunaickan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538127

5,596 views
4 citations

Original Research

Published on 04 Feb 2025

Staphylococcus aureus-specific TIGIT+ Treg are present in the blood of healthy subjects – a hurdle for vaccination?

in Microbial Immunology

Jonah Clegg
Malgorzata E. Mnich
Alberto Carignano
Giovanni Cova
Simona Tavarini
Chiara Sammicheli
Bruna Clemente
Megan Smith
Emilio Siena
Monia Bardelli

Frontiers in Immunology

doi 10.3389/fimmu.2024.1500696

5,110 views
3 citations

Review

Published on 03 Feb 2025

Management of tuberculosis risk, screening and preventive therapy in patients with chronic autoimmune arthritis undergoing biotechnological and targeted immunosuppressive agents

in Microbial Immunology

Andrea Picchianti-Diamanti
Alessandra Aiello
Chiara De Lorenzo
Giovanni Battista Migliori
Delia Goletti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1494283

10,263 views
15 citations

Original Research

Published on 03 Feb 2025

Hypoxia-driven mobilization of altruistic cancer stem cells in platinum-treated head and neck cancer

in Microbial Immunology

Lekhika Pathak
Bidisha Pal
Joyeeta Talukdar
Partha Jyoti Saikia
Sorra Sandhya
Wale Tasabehji
Hong Li
Jyotirmoy Phukan
Anjan Bhuyan
Sanjukta Patra

Frontiers in Immunology

doi 10.3389/fimmu.2024.1336882

4,265 views
2 citations

Technology and Code

Published on 31 Jan 2025

Gene prediction of immune cells association between gut microbiota and colorectal cancer: a Mendelian randomization study

in Microbial Immunology

Yan Zhong
Guanglei Chen
Menglu Chen
Junsong Cui
Qianren Tan
Zhenghua Xiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1460936

5,657 views
3 citations

Original Research

Published on 30 Jan 2025

Deciphering the functional roles of PE18 and PPE26 proteins in modulating Mycobacterium tuberculosis pathogenesis and immune response

in Microbial Immunology

Aquib Ehtram
Mohd Shariq
Neha Quadir
Salma Jamal
Manjunath Pichipalli
Sheeba Zarin
Javaid Ahmad Sheikh
Nasreen Z. Ehtesham
Seyed E. Hasnain

Frontiers in Immunology

doi 10.3389/fimmu.2025.1517822

4,409 views
5 citations

Systematic Review

Published on 30 Jan 2025

Systematic review of innate immune responses against Mycobacterium tuberculosis complex infection in animal models

in Microbial Immunology

Luisa Maria Nieto Ramirez
Carolina Mehaffy
Karen Marie Dobos

Frontiers in Immunology

doi 10.3389/fimmu.2024.1467016

7,608 views
9 citations

Correction

Published on 30 Jan 2025

Corrigendum: Longitudinal mitochondrial bioenergetic signatures of blood monocytes and lymphocytes improve during treatment of drug-susceptible pulmonary tuberculosis patients

in Microbial Immunology

Bridgette M. Cumming
Kelvin W. Addicott
Fernanda Maruri
Vanessa Pillay
Rukaya Asmal
Sashen Moodley
Beatriz Barreto-Durate
Mariana Araújo-Pereira
Matilda Mazibuko
Zoey Mhlane

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557327

1,562 views

Original Research

Published on 28 Jan 2025

Ablation of the deubiquitinating enzyme cylindromatosis (CYLD) augments STAT1-mediated M1 macrophage polarization and fosters Staphylococcus aureus control

in Microbial Immunology

Christina Schmidt
Kunjan Harit
Stephan Traidl
Michael Naumann
Thomas Werfel
Lennart M. Roesner
Gopala Nishanth
Dirk Schlüter

Frontiers in Immunology

doi 10.3389/fimmu.2025.1507989

4,453 views
3 citations

2,983 articles

articles

Immune mediators as plasma biomarkers for identifying household contacts and classifying clinical forms and leprosy reactions

Advancements in the investigation of gut microbiota-based strategies for stroke prevention and treatment

Post-stroke depression: exploring gut microbiota-mediated barrier dysfunction through immune regulation

Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing

Unveiling the immunological landscape of disseminated tuberculosis: a single-cell transcriptome perspective

Mycobacterium tuberculosis infection may increase the degrees of malignancy in lung adenocarcinoma

Case Report: First report of Legionella micdadei pneumonia and organizing pneumonia in a patient with myelodysplastic and Sweet syndromes

Association of systemic inflammation response index with latent tuberculosis infection and all-cause mortality: a cohort study from NHANES 2011-2012

Chaihushugan powder regulates the gut microbiota to alleviate mitochondrial oxidative stress in the gastric tissues of rats with functional dyspepsia

Caspase-11 and NLRP3 exacerbate systemic Klebsiella infection through reducing mitochondrial ROS production

Patchoulene epoxide mitigates colitis and hepatic damage induced by dextran sulfate sodium by regulating the colonic microbiota and purine metabolism

Big lessons from the little Akkermansia muciniphila in hepatocellular carcinoma

Implications of intratumoral microbiota in tumor metastasis: a special perspective of microorganisms in tumorigenesis and clinical therapeutics

The role of short-chain fatty acid in metabolic syndrome and its complications: focusing on immunity and inflammation

Characteristics, pathogenic and therapeutic role of gut microbiota in immunoglobulin A nephropathy

The importance of inflammatory biomarkers in detecting and managing latent tuberculosis infection

Staphylococcus aureus-specific TIGIT+ Treg are present in the blood of healthy subjects – a hurdle for vaccination?

Management of tuberculosis risk, screening and preventive therapy in patients with chronic autoimmune arthritis undergoing biotechnological and targeted immunosuppressive agents

Hypoxia-driven mobilization of altruistic cancer stem cells in platinum-treated head and neck cancer

Gene prediction of immune cells association between gut microbiota and colorectal cancer: a Mendelian randomization study

Deciphering the functional roles of PE18 and PPE26 proteins in modulating Mycobacterium tuberculosis pathogenesis and immune response

Systematic review of innate immune responses against Mycobacterium tuberculosis complex infection in animal models

Corrigendum: Longitudinal mitochondrial bioenergetic signatures of blood monocytes and lymphocytes improve during treatment of drug-susceptible pulmonary tuberculosis patients

Ablation of the deubiquitinating enzyme cylindromatosis (CYLD) augments STAT1-mediated M1 macrophage polarization and fosters Staphylococcus aureus control