Frontiers in Immunology | Microbial Immunology

Review

Accepted on 19 Dec 2025

Probiotics and human health: Biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - A comprehensive review

in Microbial Immunology

Mohamed T. El-Saadony
Ahmed M. Saad
Mahmoud Sitohy
Samar Sami Alkafaas
Mthokozisi Dladla
Soumya Ghosh
Dr. Dina Mostafa Mohammed
Essam Ibrahim
Mohamed A. Fahmy
Amr Elkelish

Frontiers in Immunology

398 views

Review

Published on 19 Dec 2025

The role of Akkermansia muciniphila in the regulation of inflammatory bowel disease: intestinal immunity and metabolism

in Microbial Immunology

Wang Xu
Aijing Li
Huijuan Jing
Xiaoping Zhang
Xucheng Dong
Zhiqiang Song
Nanping Wu
Shufa Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653472

2,007 views

Review

Published on 19 Dec 2025

Precision bacterial immunotherapy: an integrated mechanistic taxonomy and translational roadmap against antimicrobial resistance

in Microbial Immunology

Hamdi Al-Azzani
Djandan Tadum Arthur Vithran
Hanane Aliouat
Wenhu Zhou
Xiaoqiang Mao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675682

1,463 views

Review

Published on 17 Dec 2025

Ferroptosis in human reproductive tract infections and associated disorders: mechanisms and emerging therapeutic opportunities

in Microbial Immunology

Xinchen Wan
Xue Wang
Yanjun Liu
Longyan Hong
Zhandi Zhao
Pengbo Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713074

2,338 views

Perspective

Published on 17 Dec 2025

Microbiota and antibiotic exposure in sarcoidosis

in Microbial Immunology

Claudio Ucciferri
Livia Moffa
Claudio Tana

Frontiers in Immunology

doi 10.3389/fimmu.2025.1737273

1,387 views

Original Research

Published on 16 Dec 2025

Isolation of a nanobody specific to the PstS-1 protein and evaluation of its immunoreactivity with structural components of Mycobacterium tuberculosis granuloma

in Microbial Immunology

Yogesh P. Dhekale
Kumarasamy Jothivel
Samar Kumar Ghorui
Gagan Deep Gupta
Shweta Singh
Nawab Singh Baghel
Savita Kulkarni
Pramod Kumar Gupta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684904

1,733 views

Review

Published on 16 Dec 2025

Pathogenic mechanisms and therapeutic potential of the microbiome in premature ovarian insufficiency

in Microbial Immunology

Shuai Ma
Lianwen Zheng
Xiaohua Zhuang
Min Wang
Yinggang Zou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1734367

1,806 views

Review

Published on 15 Dec 2025

Exploring gut microbiota and spinal cord injury: pathogenesis, treatment strategies and prospects

in Microbial Immunology

Qin Chen
Mingliang Zhong
Ye Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693883

1,456 views

Original Research

Published on 15 Dec 2025

Regulation of neutrophil extracellular trap formation by c-di-GMP in Pseudomonas aeruginosa-induced pleural infection

in Microbial Immunology

Cao Qing
WenHui Huang
Lilu Shi
Jing Luo
Shaochu Zheng
Jinliang Kong
Ke Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610266

1,254 views

Original Research

Published on 12 Dec 2025

Organosilicone double-long-chain diquaternary ammonium salt acts as a biofilm scavenger to ameliorate colitis induced by dextran sulfate sodium salt

in Microbial Immunology

Shaopei Shi
Guoxing Tang
Juan Wei
Si Shen
Zhihao Ding
Qin An
Hui Tao
Fangyu Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644433

931 views

Review

Published on 11 Dec 2025

The role of nucleic acid sensors in antifungal immunity

in Microbial Immunology

Xinyu Liang
Hui Zhou
Litong Ouyang
Jiming Chen
Wenji He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1725717

987 views

Original Research

Published on 09 Dec 2025

The role of leptospiral proteins in immune evasion and inflammatory response stimulation in HEK293T cell monolayers

in Microbial Immunology

Igor R. M. Silva
Aline F. Teixeira
Ana L. T. O. Nascimento

Frontiers in Immunology

doi 10.3389/fimmu.2025.1689798

999 views

Original Research

Published on 08 Dec 2025

Bystander CD8+ conventional memory versus virtual memory T cells in the initial days post-Trypanosoma cruzi infection

in Microbial Immunology

Maria Estefania Viano
Ruth Eliana Baigorri
Gastón Bergero
Maria Pilar Aoki
Nicolas Leonel Lidon
Maria Guadalupe Teixeira
Melisa Rocio Herrera
Claudia Cristina Motran
Fabio Marcelo Cerban
Cinthia Carolina Stempin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1674964

1,396 views

Review

Published on 08 Dec 2025

Gut microbiome, a novel precision medicine biomarker for hepatocellular carcinoma

in Microbial Immunology

Pin-Jung Chen
Suzanne Devkota
Stephen Shiao
Andrew Hendifar
Ju Dong Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568962

1,782 views

Original Research

Published on 05 Dec 2025

IL-1β, TNF-α, and IL-10 reduce cell viability and differentially alter biofilm structure and gene expression levels in Staphylococcus aureus USA 300

in Microbial Immunology

Adriana N. Zavala-Hernández
Christian Salto-Reyes
Alejandro Bravo-Patiño
Víctor M. Baizabal-Aguirre
Juan J. Valdez-Alarcón

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665397

1,228 views

Systematic Review

Published on 05 Dec 2025

Risk factors of serofast state in patients undergoing syphilis: a meta-analysis of 17 cohort studies

in Microbial Immunology

Xin Zeng
Yuan Ouyang
Haoyun Wang
Linna Liu
Jiaxin Chen
Chengbin Zhu
Hong Huang
Jin Lin
Yanan Niu
Lan Liao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1689904

1,515 views

Original Research

Published on 04 Dec 2025

Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages

in Microbial Immunology

Md Shoykot Jahan
Jinlan Yang
Yiyue Tang
Dehui Xiong
Peilei Hu
Xichang Tang
Lijun Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1676204

1,284 views

Original Research

Published on 03 Dec 2025

Restoration of peripheral ILC3s by washed microbiota transplantation improves lipid profiles in hyperlipidemia patients

in Microbial Immunology

Yao-Fei Wei
Yi-Shu Wang
Jia-Yin Song
Hao Wang
Xing-Xiang He
Hao-Jie Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1688070

1,570 views

Original Research

Published on 03 Dec 2025

Impact of chronic social stress on molecular markers of skin regeneration during experimental excisional wounding

in Microbial Immunology

Lyudmyla Makyeyeva
Igor Belenichev
Olena Aliyeva
Oleksandr Frolov
Pavlo Petakh
Oleksandr Kamyshnyi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656214

1,347 views

Original Research

Published on 03 Dec 2025

Gut microbiota-driven dysbiosis of the SCFA-immune axis in pediatric allergic rhinitis-constipation comorbidity: mechanisms and synbiotic remodeling

in Microbial Immunology

WeiKeng Yang
Xiaojiao Zhang
Bin Wu
Binyu Ni
Hongbin Lin
Congfu Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639359

1,613 views

Correction

Published on 02 Dec 2025

Correction: Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line

in Microbial Immunology

Natalia Garcia-Gonzalez
Charlotte Wallaeys
Wendy Toussaint
Tino Hochepied
Sylviane Dewaele
Somara De Beul
Robin Van Loke
Jolien Vandewalle
Steven Timmermans
Richard S. Blumberg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1733126

558 views

Review

Accepted on 01 Dec 2025

Multi-Omics Reveals Circadian Regulation of Bone Homeostasis by Gut Microbiota Metabolites: Mechanisms and Chronotherapeutic Implications

in Microbial Immunology

Mingdong Liu
Jiaqi Gong
Yaqi Liu
Jiayao Yu
Zepeng Hu
Zheng Liu

Frontiers in Immunology

219 views

Original Research

Published on 01 Dec 2025

Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence

in Microbial Immunology

Aling Tang
Zhimin Gong
Yi Shi
Weizhen Zhang
Mingming Jin
Lichao Sun
Wei Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1674678

1,862 views

Original Research

Published on 01 Dec 2025

Commensal Staphylococci attenuate Staphylococcus aureus skin colonization and inflammation via AHR-dependent signaling

in Microbial Immunology

Jule Riebelmann
Nicole Kienzle
Birgit Sauer
Birgit Schittek

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726557

1,875 views

2,980 articles

articles

Probiotics and human health: Biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - A comprehensive review

The role of Akkermansia muciniphila in the regulation of inflammatory bowel disease: intestinal immunity and metabolism

Precision bacterial immunotherapy: an integrated mechanistic taxonomy and translational roadmap against antimicrobial resistance

Ferroptosis in human reproductive tract infections and associated disorders: mechanisms and emerging therapeutic opportunities

Microbiota and antibiotic exposure in sarcoidosis

Isolation of a nanobody specific to the PstS-1 protein and evaluation of its immunoreactivity with structural components of Mycobacterium tuberculosis granuloma

Pathogenic mechanisms and therapeutic potential of the microbiome in premature ovarian insufficiency

Exploring gut microbiota and spinal cord injury: pathogenesis, treatment strategies and prospects

Regulation of neutrophil extracellular trap formation by c-di-GMP in Pseudomonas aeruginosa-induced pleural infection

Organosilicone double-long-chain diquaternary ammonium salt acts as a biofilm scavenger to ameliorate colitis induced by dextran sulfate sodium salt

The role of nucleic acid sensors in antifungal immunity

The role of leptospiral proteins in immune evasion and inflammatory response stimulation in HEK293T cell monolayers

Bystander CD8+ conventional memory versus virtual memory T cells in the initial days post-Trypanosoma cruzi infection

Gut microbiome, a novel precision medicine biomarker for hepatocellular carcinoma

IL-1β, TNF-α, and IL-10 reduce cell viability and differentially alter biofilm structure and gene expression levels in Staphylococcus aureus USA 300

Risk factors of serofast state in patients undergoing syphilis: a meta-analysis of 17 cohort studies

Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages

Restoration of peripheral ILC3s by washed microbiota transplantation improves lipid profiles in hyperlipidemia patients

Impact of chronic social stress on molecular markers of skin regeneration during experimental excisional wounding

Gut microbiota-driven dysbiosis of the SCFA-immune axis in pediatric allergic rhinitis-constipation comorbidity: mechanisms and synbiotic remodeling

Correction: Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line

Multi-Omics Reveals Circadian Regulation of Bone Homeostasis by Gut Microbiota Metabolites: Mechanisms and Chronotherapeutic Implications

Causality of circulating vitamins on infectious diseases: integrating Mendelian randomization and in vivo evidence

Commensal Staphylococci attenuate Staphylococcus aureus skin colonization and inflammation via AHR-dependent signaling