Frontiers in Immunology | Molecular Innate Immunity

Original Research

Published on 16 Jul 2025

Protection against prolonged pneumococcal infection involves structural changes in C-reactive protein and subsequent binding to both phosphocholine and amyloids on the bacterial surface

in Molecular Innate Immunity

Alok Agrawal
Donald N. Ngwa
J. Paul Simons
Sanjay K. Singh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631409

2,037 views
1 citation

Mini Review

Published on 16 Jul 2025

The role of peripheral innate immune cells in Alzheimer’s disease progression

in Molecular Innate Immunity

Yanchun Cao
Ke Tang
Pengcheng Ma
Run Zhang
Yani Yang
Tingting Li
Ying Zhang
Xiaoming Peng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616939

5,701 views
3 citations

Original Research

Published on 10 Jul 2025

Spatiotemporal regulation of ventilator lung injury resolution by TGF-β1+ regulatory B cells via macrophage vesicle-nanotherapeutics

in Molecular Innate Immunity

Ren Jing
Xiaoting Liao
Jianlan Mo
Sheng He
Xianlong Xie
Zhaokun Hu
Linghui Pan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635178

2,550 views
2 citations

Mini Review

Published on 09 Jul 2025

Dopamine as an endogenous regulator of innate immunity in sepsis

in Molecular Innate Immunity

Haichao Wang
Rui Kang
Daolin Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625368

3,678 views
1 citation

Review

Published on 09 Jul 2025

The lactylation-macrophage interplay: implications for gastrointestinal disease therapeutics

in Molecular Innate Immunity

Xinzhen Che
Yixin Zhang
Xiqi Chen
Guangdong Xie
Jinling Li
Chengchao Xu
Chunhua Zhang
Yong Zhu
Xinyu Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608115

9,263 views
5 citations

Review

Published on 04 Jul 2025

Regulation of dendritic cell biology by amino acids and their transporters

in Molecular Innate Immunity

Shanlin Chen
Gongwei Li
Zihao Jiang
Yuekang Xu
Adila Aipire
Jinyao Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626973

3,867 views
2 citations

Review

Published on 04 Jul 2025

Anti-HBV treatment partially restores the dysfunction of innate immune cells and unconventional T cells during chronic HBV infection

in Molecular Innate Immunity

Yiwen Shu
Sumeng Li
Yanqin Du
Xin Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611976

4,603 views
5 citations

Review

Published on 03 Jul 2025

Bacterial interactions with platelets: defining key themes

in Molecular Innate Immunity

Hammodah R. Alfar
Sidney W. Whiteheart

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610289

3,236 views
2 citations

Opinion

Published on 02 Jul 2025

B-cell epitope prediction for developing allergy vaccines and their companion immunodiagnostics

in Molecular Innate Immunity

Robbi Miguel G. Falcon
Serina U. Fahrenbach
Louise Claire E. Ortiz
Salvador Eugenio C. Caoili

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624339

2,331 views

Original Research

Published on 30 Jun 2025

Single-cell RNA-sequencing highlights a curtailed NK cell function in convalescent COVID-19 pregnant women

in Molecular Innate Immunity

Madhuri S. Salker
Nor Haslinda Abd Aziz
Natalia Carman Prodan
Zhiqi Yang
Aditya Kumar Lankapalli
Katrin Lazar
Mohamad Nasir Shafiee
Ersoy Kocak
Harivignesh Ganesan
Surya Sekhar Pal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1560391

3,758 views

Review

Published on 25 Jun 2025

Pyroptosis as a therapeutic target in preeclampsia: current research and future directions

in Molecular Innate Immunity

Yongchun Zhu
Yuting Xiang
Sathiskumar Swamiappan
Zhongjun Li
Xinsheng Peng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622550

4,196 views
2 citations

Original Research

Published on 23 Jun 2025

Single-cell transcriptomic and m6A methylation analyses reveal platelet-mediated immune regulatory mechanisms in sepsis

in Molecular Innate Immunity

Weiwei Qian
Yuanyuan Liu
Xinyang Zhao
Yuxin Dong
Jian Zhou
Songtao Shou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607732

4,359 views
2 citations

Original Research

Published on 23 Jun 2025

MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis

in Molecular Innate Immunity

Nirmal Parajuli
Yi Yao
Namir Khalasawi
Congcong Yin
Qiong Zhang
Indra Adrianto
Aakash Hans
Li Zhou
Qing-Sheng Mi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598306

3,838 views
3 citations

Original Research

Published on 20 Jun 2025

C3d-targeted complement inhibitors to correct complement dysregulation in aHUS patients

in Molecular Innate Immunity

Valeria Guaschino
Donata Santarsiero
Sara Gastoldi
Joshua M. Thurman
V. Michael Holers
Shelia M. Violette
Fei Liu
Kelly C. Fahnoe
Chiara Guarinoni
Ariela Benigni

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620996

3,771 views

Review

Published on 19 Jun 2025

Impact of smoking on the complement system: a narrative review

in Molecular Innate Immunity

Ahmed B. Alarabi
Fatima Z. Alshbool
Fadi T. Khasawneh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1619835

3,179 views
1 citation

Original Research

Published on 19 Jun 2025

Bridging aging, immunity, and atherosclerosis: novel insights into senescence-related genes

in Molecular Innate Immunity

Yan Lu
Rong Yuan
Qiqi Xin
Keji Chen
Weihong Cong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557266

4,884 views

Mini Review

Published on 18 Jun 2025

Pro-inflammatory granzyme K contributes extracellularly to disease

in Molecular Innate Immunity

Christopher T. Turner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620670

6,880 views
5 citations

Original Research

Published on 18 Jun 2025

Identification and validation of NETs-related biomarkers in active tuberculosis through bioinformatics analysis and machine learning algorithms

in Molecular Innate Immunity

Shengfang Xia
Qi An
Rui Lin
Yalan Tu
Zhu Chen
Dongmei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599667

4,575 views
2 citations

Original Research

Published on 18 Jun 2025

Integrative multi-omics analysis of IFNγ-induced macrophages and atherosclerotic plaques reveals macrophage-dependent STAT1-driven transcription in atherosclerosis

in Molecular Innate Immunity

Mahdi Eskandarian Boroujeni
Natalia Lopacinska
Aleksandra Antonczyk
Katarzyna Kluzek
Joanna Wesoly
Hans A. R. Bluyssen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590953

21,249 views
4 citations

Editorial

Published on 18 Jun 2025

Editorial: A new perspective in immune polymorphism (the HLA, KIR, and LILR genes)

in Molecular Innate Immunity

Seik-Soon Khor
Martin Maiers
Jason Krawic
Danillo G. Augusto
Aisha Souquette

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640672

1,741 views

Original Research

Published on 18 Jun 2025

In evolution’s unending race: ancestral STING sensors in Salmo salar mediate intracellular bacterial detection and programmed cell death through evolutionarily conserved pathways

in Molecular Innate Immunity

Alejandro J. Yañez
Jorge F. Beltrán
Claudia A. Barrientos
Genaro Soto-Rauch
Marcelo Aguilar
Adolfo Isla
Sandra N. Flores-Martin
Francisco T. Yañez
Yassef Yuivar
Adriana Ojeda

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570871

3,060 views

Correction

Published on 13 Jun 2025

Corrigendum: 17β-Estradiol promotes trained immunity in female against sepsis via regulating nucleus translocation of RelB

in Molecular Innate Immunity

Zhiheng Sun
Yuchen Pan
Junxing Qu
Yujun Xu
Huan Dou
Yayi Hou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629629

1,161 views

Editorial

Published on 10 Jun 2025

Editorial: Cell death in innate immunity and inflammatory diseases

in Molecular Innate Immunity

Malvina Pizzuto
Chiara Cipollina

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635279

1,941 views

Editorial

Published on 09 Jun 2025

Editorial: Innate immune dysregulation: a driving force of autoimmunity and chronic inflammation

in Molecular Innate Immunity

Reza Akbarzadeh
Jens Y. Humrich
Tamás Németh
Kyle T. Amber

Frontiers in Immunology

doi 10.3389/fimmu.2025.1632416

3,724 views
4 citations

3,602 articles

articles

Protection against prolonged pneumococcal infection involves structural changes in C-reactive protein and subsequent binding to both phosphocholine and amyloids on the bacterial surface

The role of peripheral innate immune cells in Alzheimer’s disease progression

Spatiotemporal regulation of ventilator lung injury resolution by TGF-β1+ regulatory B cells via macrophage vesicle-nanotherapeutics

Dopamine as an endogenous regulator of innate immunity in sepsis

The lactylation-macrophage interplay: implications for gastrointestinal disease therapeutics

Regulation of dendritic cell biology by amino acids and their transporters

Anti-HBV treatment partially restores the dysfunction of innate immune cells and unconventional T cells during chronic HBV infection

Bacterial interactions with platelets: defining key themes

B-cell epitope prediction for developing allergy vaccines and their companion immunodiagnostics

Single-cell RNA-sequencing highlights a curtailed NK cell function in convalescent COVID-19 pregnant women

Pyroptosis as a therapeutic target in preeclampsia: current research and future directions

Single-cell transcriptomic and m6A methylation analyses reveal platelet-mediated immune regulatory mechanisms in sepsis

MicroRNAs regulate alveolar macrophage homeostasis and its function in lung fibrosis

C3d-targeted complement inhibitors to correct complement dysregulation in aHUS patients

Impact of smoking on the complement system: a narrative review

Bridging aging, immunity, and atherosclerosis: novel insights into senescence-related genes

Pro-inflammatory granzyme K contributes extracellularly to disease

Identification and validation of NETs-related biomarkers in active tuberculosis through bioinformatics analysis and machine learning algorithms

Integrative multi-omics analysis of IFNγ-induced macrophages and atherosclerotic plaques reveals macrophage-dependent STAT1-driven transcription in atherosclerosis

Editorial: A new perspective in immune polymorphism (the HLA, KIR, and LILR genes)

In evolution’s unending race: ancestral STING sensors in Salmo salar mediate intracellular bacterial detection and programmed cell death through evolutionarily conserved pathways

Corrigendum: 17β-Estradiol promotes trained immunity in female against sepsis via regulating nucleus translocation of RelB

Editorial: Cell death in innate immunity and inflammatory diseases

Editorial: Innate immune dysregulation: a driving force of autoimmunity and chronic inflammation