Frontiers in Immunology | Molecular Innate Immunity

Original Research

Published on 16 Jan 2025

Potential implications of granzyme B in keloids and hypertrophic scars through extracellular matrix remodeling and latent TGF-β activation

in Molecular Innate Immunity

Alexandre Aubert
Jenna Goeres
Amy Liu
Martin Kao
Katlyn C. Richardson
Karen Jung
Boris Hinz
Richard I. Crawford
David J. Granville

Frontiers in Immunology

doi 10.3389/fimmu.2024.1484462

598 views

Review

Published on 14 Jan 2025

Mitochondrial dysfunction in Alzheimer’s disease: a key frontier for future targeted therapies

in Molecular Innate Immunity

Shuguang Wang
Zuning Liao
Qiying Zhang
Xinyuan Han
Changqing Liu
Jin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1484373

794 views

Original Research

Published on 14 Jan 2025

A c-type lectin HcLec1 with dual function of immunology and mineralization from the freshwater oyster (Hyriopsis cumingii Lea)

in Molecular Innate Immunity

Xiaofeng Chen
Xiaoya Shen
Shijun Liu
Wenjuan Li
He Wang
Jiale Li
Zhiyi Bai

Frontiers in Immunology

doi 10.3389/fimmu.2024.1530732

318 views

Review

Accepted on 13 Jan 2025

Factor B as a therapeutic target for the treatment of complementmediated diseases

in Molecular Innate Immunity

David Kavanagh
Jonathan Barratt
Anna Schubart
Nicholas JA Webb
Matthias Meier
Fadi Fakhouri

Frontiers in Immunology

doi 10.3389/fimmu.2025.1537974

159 views

Original Research

Published on 13 Jan 2025

The immune landscape of fetal chorionic villous tissue in term placenta

in Molecular Innate Immunity

Brianna M. Doratt
Heather E. True
Suhas Sureshchandra
Qi Qiao
Monica Rincon
Nicole E. Marshall
Ilhem Messaoudi

Frontiers in Immunology

doi 10.3389/fimmu.2024.1506305

772 views

Review

Published on 10 Jan 2025

The role of M1/M2 macrophage polarization in the pathogenesis of obesity-related kidney disease and related pathologies

in Molecular Innate Immunity

Periklis Dousdampanis
Ioanna Aggeletopoulou
Athanasia Mouzaki

Frontiers in Immunology

doi 10.3389/fimmu.2024.1534823

930 views

Original Research

Published on 07 Jan 2025

NR2F6 regulates stem cell hematopoiesis and myelopoiesis in mice

in Molecular Innate Immunity

Johannes Woelk
Hamsa Narasimhan
Christa Pfeifhofer-Obermair
Barbara U. Schraml
Natascha Hermann-Kleiter

Frontiers in Immunology

doi 10.3389/fimmu.2024.1404805

632 views

Original Research

Published on 07 Jan 2025

Titanium nanotubes modulate immunophenotyping and cytokine secretion of T cells via IL-17A: a bioinformatic analysis and experimental validation

in Molecular Innate Immunity

Jingju Yin
Yunyang Liao
Shaofeng Liu
Bangwei Che
Hanghang Zhu
Bingbing Yang
Bin Shi

Frontiers in Immunology

doi 10.3389/fimmu.2024.1381158

334 views

Original Research

Published on 07 Jan 2025

Recognition of Staphylococcus aureus by the pattern recognition molecules langerin, mannan-binding lectin, and surfactant protein D: the influence of capsular polysaccharides and wall teichoic acid

in Molecular Innate Immunity

Kirstine Mejlstrup Hymøller
Stig Hill Christiansen
Anders Grønnegaard Schlosser
Uffe B. Skov Sørensen
Jean C. Lee
Steffen Thiel

Frontiers in Immunology

doi 10.3389/fimmu.2024.1504886

647 views

Editorial

Published on 03 Jan 2025

Editorial: Enhancing innate immunity in combination therapy for solid tumors

in Molecular Innate Immunity

David Pejoski

Frontiers in Immunology

doi 10.3389/fimmu.2024.1539027

287 views

Original Research

Published on 23 Dec 2024

Characterization of a novel AEL allele harboring a c.28 + 5G>A mutation on the ABO*A2.01 background: a study utilizing PacBio third-generation sequencing and functional assays

in Molecular Innate Immunity

Lin-Nan Shao
Wen-Qian Song
Lu Zhou
Ling-Zi Pan
Ying Duan
Nan Xiao
Shi-Hang Zhou
Xiao-Hua Liang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1396426

362 views

Review

Published on 23 Dec 2024

Connexin 43 and Pannexin 1 hemichannels as endogenous regulators of innate immunity in sepsis

in Molecular Innate Immunity

Jianhua Li
Li Lou
Weiqiang Chen
Xiaoling Qiang
Cassie Zhu
Haichao Wang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1523306

794 views

Methods

Published on 19 Dec 2024

The development of murine bone marrow-derived mast cells expressing functional human MRGPRX2 for ex vivo and in vivo studies

in Molecular Innate Immunity

Maram Bawazir
Saptarshi Roy
Hydar Ali

Frontiers in Immunology

doi 10.3389/fimmu.2024.1523393

770 views

Review

Published on 17 Dec 2024

O-GlcNAcylation dictates pyroptosis

in Molecular Innate Immunity

Yue Lang
Jincheng Li
Leiliang Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1513542

1,155 views

Review

Published on 17 Dec 2024

Revisiting surfactant protein D: an immune surveillance molecule bridging innate and adaptive immunity

in Molecular Innate Immunity

Azra Shamim
Mughair Abdul Aziz
Faryal Saeed
Rekha Kumari
Ann Mary Joseph
Pretty Ponnachan
Uday Kishore
Khaled Masmoudi

Frontiers in Immunology

doi 10.3389/fimmu.2024.1491175

996 views

Review

Published on 16 Dec 2024

Progress of cGAS-STING signaling pathway-based modulation of immune response by traditional Chinese medicine in clinical diseases

in Molecular Innate Immunity

Hui Zhi
Hui Fu
Yunxin Zhang
Ni Fan
Chengcheng Zhao
Yunfei Li
Yujiao Sun
Yingpeng Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1510628

1,111 views

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Articles

Potential implications of granzyme B in keloids and hypertrophic scars through extracellular matrix remodeling and latent TGF-β activation

Mitochondrial dysfunction in Alzheimer’s disease: a key frontier for future targeted therapies

A c-type lectin HcLec1 with dual function of immunology and mineralization from the freshwater oyster (Hyriopsis cumingii Lea)

Factor B as a therapeutic target for the treatment of complementmediated diseases

The immune landscape of fetal chorionic villous tissue in term placenta

The role of M1/M2 macrophage polarization in the pathogenesis of obesity-related kidney disease and related pathologies

NR2F6 regulates stem cell hematopoiesis and myelopoiesis in mice

Titanium nanotubes modulate immunophenotyping and cytokine secretion of T cells via IL-17A: a bioinformatic analysis and experimental validation

Recognition of Staphylococcus aureus by the pattern recognition molecules langerin, mannan-binding lectin, and surfactant protein D: the influence of capsular polysaccharides and wall teichoic acid

Editorial: Enhancing innate immunity in combination therapy for solid tumors

Characterization of a novel AEL allele harboring a c.28 + 5G>A mutation on the ABO*A2.01 background: a study utilizing PacBio third-generation sequencing and functional assays

Connexin 43 and Pannexin 1 hemichannels as endogenous regulators of innate immunity in sepsis

The development of murine bone marrow-derived mast cells expressing functional human MRGPRX2 for ex vivo and in vivo studies

O-GlcNAcylation dictates pyroptosis

Revisiting surfactant protein D: an immune surveillance molecule bridging innate and adaptive immunity

Progress of cGAS-STING signaling pathway-based modulation of immune response by traditional Chinese medicine in clinical diseases