Frontiers in Immunology | Molecular Innate Immunity

Original Research

Published on 04 Sep 2023

ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development

in Molecular Innate Immunity

Yifan Lu
Yu Sun
Fatma Saaoud
Ying Shao
Keman Xu
Xiaohua Jiang
Sheng Wu
Jun Yu
Nathaniel W. Snyder
Ling Yang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1268916

6,784 views
17 citations

Original Research

Published on 01 Sep 2023

Pentameric C-reactive protein is a better prognostic biomarker and remains elevated for longer than monomeric CRP in hospitalized patients with COVID-19

in Molecular Innate Immunity

Francis R. Hopkins
Johan Nordgren
Rafael Fernandez-Botran
Helena Enocsson
Melissa Govender
Cecilia Svanberg
Lennart Svensson
Marie Hagbom
Åsa Nilsdotter-Augustinsson
Sofia Nyström

Frontiers in Immunology

doi 10.3389/fimmu.2023.1259005

3,601 views
3 citations

Original Research

Published on 31 Aug 2023

C-reactive protein binds to short phosphoglycan repeats of Leishmania secreted proteophosphoglycans and activates complement

in Molecular Innate Immunity

Eu Shen Seow
Eve C. Doran
Jan-Hendrik Schroeder
Matthew E. Rogers
John G. Raynes

Frontiers in Immunology

doi 10.3389/fimmu.2023.1256205

2,929 views
4 citations

Original Research

Published on 30 Aug 2023

Novel XBP1s-independent function of IRE1 RNase in HIF-1α-mediated glycolysis upregulation in human macrophages upon stimulation with LPS or saturated fatty acid

in Molecular Innate Immunity

Margaud Iovino
Megan Colonval
Chloé Wilkin
Laurent L’homme
Cédric Lassence
Manon Campas
Olivier Peulen
Pascal de Tullio
Jacques Piette
Sylvie Legrand-Poels

Frontiers in Immunology

doi 10.3389/fimmu.2023.1204126

7,268 views
10 citations

Original Research

Published on 29 Aug 2023

Structural basis of IRGB10 oligomerization by GTP hydrolysis

in Molecular Innate Immunity

Hyun Ji Ha
Ju Hyeong Kim
Gwan Hee Lee
Subin Kim
Hyun Ho Park

Frontiers in Immunology

doi 10.3389/fimmu.2023.1254415

2,326 views
2 citations

Original Research

Published on 24 Aug 2023

MyD88-dependent Toll-like receptor 2 signaling modulates macrophage activation on lysate-adsorbed Teflon™ AF surfaces in an in vitro biomaterial host response model

in Molecular Innate Immunity

Laura A. McKiel
Laurel L. Ballantyne
Gian Luca Negri
Kimberly A. Woodhouse
Lindsay E. Fitzpatrick

Frontiers in Immunology

doi 10.3389/fimmu.2023.1232586

5,474 views
7 citations

Editorial

Published on 24 Aug 2023

Editorial: Molecular innate immunity and AI data analysis in hepatic diseases

in Molecular Innate Immunity

Li Wang
Qian Liu
Min Yao

Frontiers in Immunology

doi 10.3389/fimmu.2023.1276111

1,572 views

Review

Published on 23 Aug 2023

Neutrophil extracellular traps mediate deep vein thrombosis: from mechanism to therapy

in Molecular Innate Immunity

Mengting Yao
Jiacheng Ma
Dongwen Wu
Chucun Fang
Zilong Wang
Tianting Guo
Jianwen Mo

Frontiers in Immunology

doi 10.3389/fimmu.2023.1198952

17,518 views
60 citations

Original Research

Published on 23 Aug 2023

No NLRP3 inflammasome activity in kidney epithelial cells, not even when the NLRP3-A350V Muckle-Wells variant is expressed in podocytes of diabetic mice

in Molecular Innate Immunity

Sophie Carina Kunte
Julian A. Marschner
Martin Klaus
Tâmisa Honda
Chenyu Li
Manga Motrapu
Christoph Walz
Maria Lucia Angelotti
Giulia Antonelli
Maria Elena Melica

Frontiers in Immunology

doi 10.3389/fimmu.2023.1230050

5,301 views
10 citations

Review

Published on 22 Aug 2023

Protein O-GlcNAcylation in multiple immune cells and its therapeutic potential

in Molecular Innate Immunity

Huanhuan Cai
Wei Xiong
Haoyan Zhu
Qiongxin Wang
Shi Liu
Zhibing Lu

Frontiers in Immunology

doi 10.3389/fimmu.2023.1209970

6,573 views
12 citations

Original Research

Published on 22 Aug 2023

Glycolytic reprogramming in macrophages and MSCs during inflammation

in Molecular Innate Immunity

Xueping Li
Huaishuang Shen
Mao Zhang
Victoria Teissier
Ejun Elijah Huang
Qi Gao
Masanori Tsubosaka
Masakazu Toya
Junichi Kushioka
Chima V. Maduka

Frontiers in Immunology

doi 10.3389/fimmu.2023.1199751

22,299 views
47 citations

Review

Published on 17 Aug 2023

The benefits of clustering in TNF receptor superfamily signaling

in Molecular Innate Immunity

Éva S. Vanamee
Denise L. Faustman

Frontiers in Immunology

doi 10.3389/fimmu.2023.1225704

8,612 views
35 citations

Original Research

Published on 17 Aug 2023

DNA and histones impair the mechanical stability and lytic susceptibility of fibrin formed by staphylocoagulase

in Molecular Innate Immunity

Erzsébet Komorowicz
Veronika J. Farkas
László Szabó
Sophie Cherrington
Craig Thelwell
Krasimir Kolev

Frontiers in Immunology

doi 10.3389/fimmu.2023.1233128

3,441 views
4 citations

Perspective

Published on 17 Aug 2023

Therapeutic potential of TNFR2 agonists: a mechanistic perspective

in Molecular Innate Immunity

Yibo Chen
Mengmeng Jiang
Xin Chen

Frontiers in Immunology

doi 10.3389/fimmu.2023.1209188

14,558 views
12 citations

Review

Published on 17 Aug 2023

Agonism of 4-1BB for immune therapy: a perspective on possibilities and complications

in Molecular Innate Immunity

Shahram Salek-Ardakani
Dirk M. Zajonc
Michael Croft

Frontiers in Immunology

doi 10.3389/fimmu.2023.1228486

11,622 views
17 citations

Editorial

Published on 16 Aug 2023

Editorial: Community series in identification, function, and mechanisms of interferon induced genes associated with viruses, volume II

in Molecular Innate Immunity

Jieying Bai
Linzhu Ren
Chang Li

Frontiers in Immunology

doi 10.3389/fimmu.2023.1269413

1,377 views

Original Research

Published on 16 Aug 2023

Properdin inhibition ameliorates hepatic ischemia/reperfusion injury without interfering with liver regeneration in mice

in Molecular Innate Immunity

Jiro Kusakabe
Koichiro Hata
Tetsuya Tajima
Hidetaka Miyauchi
Xiangdong Zhao
Shoichi Kageyama
Tatsuaki Tsuruyama
Etsuro Hatano

Frontiers in Immunology

doi 10.3389/fimmu.2023.1174243

5,030 views
8 citations

Original Research

Published on 14 Aug 2023

Comparison of platelet-and endothelial-associated biomarkers of disease activity in people hospitalized with Covid-19 with and without HIV co-infection

in Molecular Innate Immunity

Mieke A. van der Mescht
Helen C. Steel
Zelda de Beer
Fareed Abdullah
Veronica Ueckermann
Ronald Anderson
Theresa M. Rossouw

Frontiers in Immunology

doi 10.3389/fimmu.2023.1235914

3,994 views
3 citations

Original Research

Published on 14 Aug 2023

CD62L as target receptor for specific gene delivery into less differentiated human T lymphocytes

in Molecular Innate Immunity

Laura Kapitza
Naphang Ho
Thomas Kerzel
Annika M. Frank
Frederic B. Thalheimer
Arezoo Jamali
Thomas Schaser
Christian J. Buchholz
Jessica Hartmann

Frontiers in Immunology

doi 10.3389/fimmu.2023.1183698

7,812 views
6 citations

Review

Published on 14 Aug 2023

Fibroblasts – the cellular choreographers of wound healing

in Molecular Innate Immunity

Samuel Knoedler
Sonja Broichhausen
Ruiji Guo
Ruoxuan Dai
Leonard Knoedler
Martin Kauke-Navarro
Fortunay Diatta
Bohdan Pomahac
Hans-Guenther Machens
Dongsheng Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1233800

27,976 views
75 citations

Review

Published on 11 Aug 2023

Histone deacetylase 6’s function in viral infection, innate immunity, and disease: latest advances

in Molecular Innate Immunity

Min Qu
Huijun Zhang
Pengyuan Cheng
Ashenafi Kiros Wubshet
Xiangping Yin
Xiangwei Wang
Yuefeng Sun

Frontiers in Immunology

doi 10.3389/fimmu.2023.1216548

6,560 views
19 citations

Editorial

Published on 11 Aug 2023

Editorial: Broadening our view on nucleic acid sensing: novel sensors, signaling pathways, and involvement in non-infectious diseases

in Molecular Innate Immunity

Lise Chauveau
Nadine Laguette
Natalia G. Sampaio

Frontiers in Immunology

doi 10.3389/fimmu.2023.1266732

1,659 views

Original Research

Published on 10 Aug 2023

Paneth cell dysfunction in radiation injury and radio-mitigation by human α-defensin 5

in Molecular Innate Immunity

Pradeep K. Shukla
Roshan G. Rao
Avtar S. Meena
Francesco Giorgianni
Sue Chin Lee
Preeti Raju
Nitesh Shashikanth
Chandra Shekhar
Sarka Beranova
Louisa Balazs

Frontiers in Immunology

doi 10.3389/fimmu.2023.1174140

5,418 views
12 citations

Review

Published on 10 Aug 2023

IRF7: role and regulation in immunity and autoimmunity

in Molecular Innate Immunity

Wei Ma
Gang Huang
Zhi Wang
Li Wang
Qiangguo Gao

Frontiers in Immunology

doi 10.3389/fimmu.2023.1236923

23,873 views
78 citations

3,557 articles

articles

ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development

Pentameric C-reactive protein is a better prognostic biomarker and remains elevated for longer than monomeric CRP in hospitalized patients with COVID-19

C-reactive protein binds to short phosphoglycan repeats of Leishmania secreted proteophosphoglycans and activates complement

Novel XBP1s-independent function of IRE1 RNase in HIF-1α-mediated glycolysis upregulation in human macrophages upon stimulation with LPS or saturated fatty acid

Structural basis of IRGB10 oligomerization by GTP hydrolysis

MyD88-dependent Toll-like receptor 2 signaling modulates macrophage activation on lysate-adsorbed Teflon™ AF surfaces in an in vitro biomaterial host response model

Editorial: Molecular innate immunity and AI data analysis in hepatic diseases

Neutrophil extracellular traps mediate deep vein thrombosis: from mechanism to therapy

No NLRP3 inflammasome activity in kidney epithelial cells, not even when the NLRP3-A350V Muckle-Wells variant is expressed in podocytes of diabetic mice

Protein O-GlcNAcylation in multiple immune cells and its therapeutic potential

Glycolytic reprogramming in macrophages and MSCs during inflammation

The benefits of clustering in TNF receptor superfamily signaling

DNA and histones impair the mechanical stability and lytic susceptibility of fibrin formed by staphylocoagulase

Therapeutic potential of TNFR2 agonists: a mechanistic perspective

Agonism of 4-1BB for immune therapy: a perspective on possibilities and complications

Editorial: Community series in identification, function, and mechanisms of interferon induced genes associated with viruses, volume II

Properdin inhibition ameliorates hepatic ischemia/reperfusion injury without interfering with liver regeneration in mice

Comparison of platelet-and endothelial-associated biomarkers of disease activity in people hospitalized with Covid-19 with and without HIV co-infection

CD62L as target receptor for specific gene delivery into less differentiated human T lymphocytes

Fibroblasts – the cellular choreographers of wound healing

Histone deacetylase 6’s function in viral infection, innate immunity, and disease: latest advances

Editorial: Broadening our view on nucleic acid sensing: novel sensors, signaling pathways, and involvement in non-infectious diseases

Paneth cell dysfunction in radiation injury and radio-mitigation by human α-defensin 5

IRF7: role and regulation in immunity and autoimmunity