Frontiers in Immunology | Molecular Innate Immunity

Original Research

Published on 06 May 2022

Discovery and Use of Long dsRNA Mediated RNA Interference to Stimulate Antiviral Protection in Interferon Competent Mammalian Cells

in Molecular Innate Immunity

Shawna L. Semple
Sarah K. W. Au
Rajesh A. Jacob
Karen L. Mossman
Stephanie J. DeWitte-Orr

Frontiers in Immunology

doi 10.3389/fimmu.2022.859749

9,173 views
12 citations

Perspective

Published on 06 May 2022

Functionalized Lineage Tracing Can Enable the Development of Homogenization-Based Therapeutic Strategies in Cancer

in Molecular Innate Immunity

Catherine Gutierrez
Caroline K. Vilas
Catherine J. Wu
Aziz M. Al’Khafaji

Frontiers in Immunology

doi 10.3389/fimmu.2022.859032

4,153 views
2 citations

Mini Review

Published on 06 May 2022

Macrophage: A Cell With Many Faces and Functions in Tuberculosis

in Molecular Innate Immunity

Faraz Ahmad
Anshu Rani
Anwar Alam
Sheeba Zarin
Saurabh Pandey
Hina Singh
Seyed Ehtesham Hasnain
Nasreen Zafar Ehtesham

Frontiers in Immunology

doi 10.3389/fimmu.2022.747799

33,839 views
152 citations

Original Research

Published on 06 May 2022

Evaluation of Cell Models to Study Monocyte Functions in PMM2 Congenital Disorders of Glycosylation

in Molecular Innate Immunity

Paola de Haas
Marien I. de Jonge
Hans J. P. M. Koenen
Ben Joosten
Mirian C. H. Janssen
Lonneke de Boer
Wiljan J. A. J. Hendriks
Dirk J. Lefeber
Alessandra Cambi

Frontiers in Immunology

doi 10.3389/fimmu.2022.869031

4,837 views
6 citations

Review

Published on 06 May 2022

UVB-Induced Microvesicle Particle Release and Its Effects on the Cutaneous Microenvironment

in Molecular Innate Immunity

Timothy C. Frommeyer
Michael M. Gilbert
Garrett V. Brittain
Tongfan Wu
Trang Q. Nguyen
Craig A. Rohan
Jeffrey B. Travers

Frontiers in Immunology

doi 10.3389/fimmu.2022.880850

7,268 views
27 citations

Review

Published on 06 May 2022

Post-Translational Modifications of STING: A Potential Therapeutic Target

in Molecular Innate Immunity

Jiaqi Kang
Jie Wu
Qinjie Liu
Xiuwen Wu
Yun Zhao
Jianan Ren

Frontiers in Immunology

doi 10.3389/fimmu.2022.888147

18,061 views
44 citations

Editorial

Published on 05 May 2022

Editorial: Innate Immunity in Kidney Injury, Repair and Fibrosis

in Molecular Innate Immunity

Bin Yang
Cheng Yang
Ying Wang

Frontiers in Immunology

doi 10.3389/fimmu.2022.909654

4,874 views
7 citations

Original Research

Published on 03 May 2022

A Robust Method to Store Complement C3 With Superior Ability to Maintain the Native Structure and Function of the Protein

in Molecular Innate Immunity

Anna Adler
Vivek Anand Manivel
Karin Fromell
Yuji Teramura
Kristina N. Ekdahl
Bo Nilsson

Frontiers in Immunology

doi 10.3389/fimmu.2022.891994

3,882 views
3 citations

Original Research

Published on 02 May 2022

Attenuation of Excess TNF-α Release in Crohn’s Disease by Silencing of iRHOMs 1/2 and the Restoration of TGF-β Mediated Immunosuppression Through Modulation of TACE Trafficking

in Molecular Innate Immunity

Taylor J. Louis
Ahmad Qasem
Saleh A. Naser

Frontiers in Immunology

doi 10.3389/fimmu.2022.887830

4,397 views
12 citations

Original Research

Published on 29 Apr 2022

PreS/2-21-Guided siRNA Nanoparticles Target to Inhibit Hepatitis B Virus Infection and Replication

in Molecular Innate Immunity

Lixia Gao
Jie Yang
Jutao Feng
Ziying Liu
Ying Dong
Jiangyan Luo
Liangzhentian Yu
Jiamei Wang
Hongying Fan
Weifeng Ma

Frontiers in Immunology

doi 10.3389/fimmu.2022.856463

6,056 views
11 citations

Original Research

Published on 28 Apr 2022

Inhibitory Effect of FMRFamide on NO Production During Immune Defense in Sepiella japonica

in Molecular Innate Immunity

Libing Zheng
Huimin Cao
Jiayin Qiu
Changfeng Chi

Frontiers in Immunology

doi 10.3389/fimmu.2022.825634

4,711 views
12 citations

Review

Published on 28 Apr 2022

Complement System and Alarmin HMGB1 Crosstalk: For Better or Worse

in Molecular Innate Immunity

Christine Gaboriaud
Marie Lorvellec
Véronique Rossi
Chantal Dumestre-Pérard
Nicole M. Thielens

Frontiers in Immunology

doi 10.3389/fimmu.2022.869720

6,437 views
20 citations

Original Research

Published on 27 Apr 2022

Comparison of the Toponomes of Alveolar Macrophages From Wild Type and Surfactant Protein A Knockout Mice and Their Response to Infection

in Molecular Innate Immunity

David S. Phelps
Vernon M. Chinchilli
Xuesheng Zhang
Debra Shearer
Judith Weisz
Joanna Floros

Frontiers in Immunology

doi 10.3389/fimmu.2022.853611

2,846 views

Review

Published on 27 Apr 2022

Learning to Be Elite: Lessons From HIV-1 Controllers and Animal Models on Trained Innate Immunity and Virus Suppression

in Molecular Innate Immunity

Sho Sugawara
R. Keith Reeves
Stephanie Jost

Frontiers in Immunology

doi 10.3389/fimmu.2022.858383

8,684 views
19 citations

Review

Published on 27 Apr 2022

Endoplasmic Reticulum Stress and Its Role in Homeostasis and Immunity of Central and Peripheral Neurons

in Molecular Innate Immunity

Caroline Perner
Elke Krüger

Frontiers in Immunology

doi 10.3389/fimmu.2022.859703

17,752 views
19 citations

Original Research

Published on 27 Apr 2022

Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19

in Molecular Innate Immunity

Youssif M. Ali
Nicholas J. Lynch
Priyanka Khatri
Ifeoluwa E. Bamigbola
Andrew C. Y. Chan
Munehisa Yabuki
Gregory A. Demopulos
Jonathan L. Heeney
Sumita Pai
Helen Baxendale

Frontiers in Immunology

doi 10.3389/fimmu.2022.841759

7,491 views
12 citations

Review

Published on 27 Apr 2022

Targeting PARP1 to Enhance Anticancer Checkpoint Immunotherapy Response: Rationale and Clinical Implications

in Molecular Innate Immunity

Carlos Wagner S. Wanderley
Tatiana Strava Correa
Mariana Scaranti
Fernando Queiroz Cunha
Romualdo Barroso-Sousa

Frontiers in Immunology

doi 10.3389/fimmu.2022.816642

7,425 views
32 citations

Original Research

Published on 26 Apr 2022

Rapid Inflammasome Activation Is Attenuated in Post-Myocardial Infarction Monocytes

in Molecular Innate Immunity

Hector Giral
Vedran Franke
Minoo Moobed
Maja F. Müller
Laura Lübking
Divya Maria James
Johannes Hartung
Kira Kuschnerus
Denitsa Meteva
Claudio Seppelt

Frontiers in Immunology

doi 10.3389/fimmu.2022.857455

4,909 views
8 citations

Original Research

Published on 22 Apr 2022

Propionic Acid, Induced in Gut by an Inulin Diet, Suppresses Inflammation and Ameliorates Liver Ischemia and Reperfusion Injury in Mice

in Molecular Innate Immunity

Junya Kawasoe
Yoichiro Uchida
Hiroshi Kawamoto
Tomoyuki Miyauchi
Takeshi Watanabe
Kenichi Saga
Kosuke Tanaka
Shugo Ueda
Hiroaki Terajima
Kojiro Taura

Frontiers in Immunology

doi 10.3389/fimmu.2022.862503

8,621 views
39 citations

Original Research

Published on 20 Apr 2022

Chronic Exposure to the Combination of Cigarette Smoke and Morphine Decreases CD4+ Regulatory T Cell Numbers by Reprogramming the Treg Cell Transcriptome

in Molecular Innate Immunity

Ying Shao
William Cornwell
Keman Xu
Aaron Kirchhoff
Fatma Saasoud
Yifan Lu
Xiaohua Jiang
Gerard J. Criner
Hong Wang
Thomas J. Rogers

Frontiers in Immunology

doi 10.3389/fimmu.2022.887681

10,029 views
17 citations

Original Research

Published on 20 Apr 2022

Serum Antigenome Profiling Reveals Diagnostic Models for Rheumatoid Arthritis

in Molecular Innate Immunity

Peng Han
Chao Hou
Xi Zheng
Lulu Cao
Xiaomeng Shi
Xiaohui Zhang
Hua Ye
Hudan Pan
Liang Liu
Tingting Li

Frontiers in Immunology

doi 10.3389/fimmu.2022.884462

5,621 views
10 citations

Original Research

Published on 19 Apr 2022

PI3K Signaling in Dendritic Cells Aggravates DSS-Induced Colitis

in Molecular Innate Immunity

Mario Kuttke
Dominika Hromadová
Ceren Yildirim
Julia S. Brunner
Andrea Vogel
Hannah Paar
Sophie Peters
Maria Weber
Melanie Hofmann
Martina Kerndl

Frontiers in Immunology

doi 10.3389/fimmu.2022.695576

5,916 views
9 citations

Original Research

Published on 19 Apr 2022

Oleamide-Mediated Polarization of M1 Macrophages and IL-1β Production by Regulating NLRP3-Inflammasome Activation in Primary Human Monocyte-Derived Macrophages

in Molecular Innate Immunity

Prapakorn Wisitpongpun
Pachuen Potup
Kanchana Usuwanthim

Frontiers in Immunology

doi 10.3389/fimmu.2022.856296

11,796 views
56 citations

Review

Published on 19 Apr 2022

Role of Toll-Like Receptors and Th Responses in Viral Myocarditis

in Molecular Innate Immunity

Shi-Yue Zheng
Jian-Zeng Dong

Frontiers in Immunology

doi 10.3389/fimmu.2022.843891

6,034 views
20 citations