Frontiers in Immunology | Multiple Sclerosis and Neuroimmunology

Brief Research Report

Published on 27 Oct 2025

Combination therapy of ofatumumab and daratumumab in patients with severe anti-NMDA receptor encephalitis

in Multiple Sclerosis and Neuroimmunology

Baojie Wang
Yufeng Chu
Chao Zhang
Shougang Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681884

1,753 views

Original Research

Published on 27 Oct 2025

The diagnostic and prognostic value of CXCL13, CXCL10, and CXCL8 in patients with neurosyphilis

in Multiple Sclerosis and Neuroimmunology

Hongjing Guan
Jingli Peng
Zihao Xia
Xiaoyun Di
Qin Wang
Chunmiao Zou
Rentian Cai
Chen Chen
Hongxia Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654251

1,699 views

Study Protocol

Published on 22 Oct 2025

The efficacy, safety, and pharmacokinetics/pharmacodynamics of telitacicept following efgartigimod in generalized myasthenia gravis: protocol of a randomized controlled trial

in Multiple Sclerosis and Neuroimmunology

Jia Li
Yuan Zhang
Yan Deng
Wenyu Li
Yiqi Wang
Feiteng Qi
Qiaoyi Zhang
Bingbing Wan
Xiang Li
Yiyun Weng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604786

3,166 views

Original Research

Published on 22 Oct 2025

Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040

in Multiple Sclerosis and Neuroimmunology

Peixi Zhao
Chang Guan
Jing Lu
Ying Zhang
Baitong Wang
Lin Huang
Ding Ye
Hongmei Nan
Jian Wang
Peng Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685316

2,453 views
1 citation

Original Research

Published on 20 Oct 2025

Polysialic acid restrains inflammatory monocyte maturation

in Multiple Sclerosis and Neuroimmunology

Ingredy Passos
Benjamin Peschke
Shrey Gandhi
Judith Derdelinckx
Louisa Müller-Miny
Harald Neumann
Jan D. Lünemann
Christian W. Keller

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656087

2,339 views
2 citations

Original Research

Published on 20 Oct 2025

Neutrophils from Alzheimer’s disease mice fail to phagocytose debris and show altered release of immune modulators with age

in Multiple Sclerosis and Neuroimmunology

Matthew Kays
Anna Kelly
Farrah McGinnis
Clara Woods
Emily Herron
Candice Brown
Aminata P. Coulibaly

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672768

2,916 views

Original Research

Published on 20 Oct 2025

Immune checkpoint-based biomarkers for therapeutic response in patients with multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

MariPaz López-Molina
Gabriel Torres Iglesias
Gonzalo Sáenz de Santa María-Diez
Jaime Valentín-Quiroga
Fernando Laso-García
Rebeca Gallego
Javier Pozo-Novoa
Beatriz Chamorro
Eduardo López-Collazo
Inmaculada Puertas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694021

2,322 views
1 citation

Review

Published on 15 Oct 2025

The link between gut microbiota and multiple sclerosis from the perspective of barrier function

in Multiple Sclerosis and Neuroimmunology

Jingru Ren
Zhenyu Niu
Jianchun Wang
Jing Guo
Hongjun Hao
Feng Gao
Ran Liu
Zhaoxia Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652796

5,045 views
1 citation

Original Research

Published on 13 Oct 2025

Colonization by Akkermansia muciniphila modulates central nervous system autoimmunity in an ecological context-dependent manner

in Multiple Sclerosis and Neuroimmunology

Daniel Peipert
Theresa L. Montgomery
Lucinda C. Toppen
Margaret Frances J. Lee
Matthew J. Scarborough
Dimitry N. Krementsov

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655428

3,098 views

Systematic Review

Published on 08 Oct 2025

Research on Parkinson’s disease immunotherapy: a bibliometric analysis via multiple databases

in Multiple Sclerosis and Neuroimmunology

Xinxing Fei
Shiqi Wang
Jiayi Song
Caihong Cao
Yaqian Gao
Yue Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659848

4,376 views

Perspective

Published on 07 Oct 2025

Targeting senescent microglia in progressive multiple sclerosis: a geroscience-informed approach

in Multiple Sclerosis and Neuroimmunology

Jeffrey Atkinson
Amy Dokiburra
Hayley Groover
Jonathan P. Godbout
Benjamin M. Segal
Yinan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681724

4,209 views

Review

Published on 07 Oct 2025

Glycolytic reprogramming during microglial polarization in neurological diseases

in Multiple Sclerosis and Neuroimmunology

Xiaoting Li
Congcong Fang
Yina Li
Xiaoxing Xiong
Xu Xu
Lijuan Gu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648887

5,064 views
1 citation

Review

Published on 06 Oct 2025

Neuroinflammation: targeting microglia for neuroprotection and repair after spinal cord injury

in Multiple Sclerosis and Neuroimmunology

Roberta Ramos Cavalcanti
Fernanda Martins Almeida
Ana Maria Blanco Martinez
Camila Marques Freria

Frontiers in Immunology

doi 10.3389/fimmu.2025.1670650

6,521 views
3 citations

Original Research

Published on 02 Oct 2025

Aging-dependent immunological changes in multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Andrea Iribarren-López
Laura Martins-Almeida
Jadon K Wells
Tamara Castillo-Triviño
Álvaro Prada
Hilda A Pickett
Ainhoa Alberro
David Otaegui

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663526

3,027 views
1 citation

Systematic Review

Published on 02 Oct 2025

Exploratory analysis of predictive models in the field of myelitis: a systematic review and meta-analysis

in Multiple Sclerosis and Neuroimmunology

Jingjie Huang
Yusheng Zhao
Ziyi Zhang
Yupei Cheng
Bangqi Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669338

2,237 views

Editorial

Published on 30 Sep 2025

Editorial: Remedying the injured brain in cognitive impairment: potential neuroimmune communication signaling and therapeutic opportunities

in Multiple Sclerosis and Neuroimmunology

Zhengsen Jin
Zhongdi Cai
Asma Perveen
George E. Barreto
Linlin Yin
Rong Wang
Rui Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705628

2,081 views

Mini Review

Published on 25 Sep 2025

Rediscovering parainfectious encephalopathy in the post-COVID-19 era

in Multiple Sclerosis and Neuroimmunology

Lin Bai
Chang Geng
Hongzhi Guan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634383

3,173 views

Original Research

Published on 23 Sep 2025

Morphometric MRI findings in patients with suspected autoimmune psychosis spectrum syndromes and association with EEG slowing, CSF changes, and psychometric/neuropsychological findings

in Multiple Sclerosis and Neuroimmunology

Katharina von Zedtwitz
Ludger Tebartz van Elst
Bernd Feige
Isabelle Matteit
Andrea Schlump
Thomas Lange
Kimon Runge
Kathrin Nickel
Nils Venhoff
Katharina Domschke

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648946

2,597 views
3 citations

Original Research

Published on 19 Sep 2025

Exploratory study on autoantibodies to arginine-rich human peptides mimicking Epstein-Barr virus in women with post-COVID and myalgic encephalomyelitis/chronic fatigue syndrome

in Multiple Sclerosis and Neuroimmunology

Friederike Hoheisel
Kathrin Maria Fleischer
Kerstin Rubarth
Nuno Sepúlveda
Sandra Bauer
Frank Konietschke
Claudia Kedor Peters
Annika Elisa Stein
Kirsten Wittke
Martina Seifert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650948

9,703 views
2 citations

Editorial

Published on 18 Sep 2025

Editorial: Novel CNS targeting molecules, methods, and therapeutics in multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Rune Alexander Aamodt Høglund
Stella E. Tsirka
Makoto Inoue

Frontiers in Immunology

doi 10.3389/fimmu.2025.1699850

3,202 views

Original Research

Published on 18 Sep 2025

Human pluripotent stem cell–derived neuronal progenitor cells promote neurogenesis and functional recovery by attenuating neuroinflammation and via extracellular vesicles in a subacute stroke model

in Multiple Sclerosis and Neuroimmunology

Hyun-Jin Kim
Dong Hee Kim
Jee In Choi
Hye Ryeong Sim
Sangyong Jung
Dong-Youn Hwang
MinYoung Kim

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650092

3,424 views

Editorial

Published on 15 Sep 2025

Editorial: Bone marrow aging and its impact on immunosenescence in neurological diseases

in Multiple Sclerosis and Neuroimmunology

Junchi He
William G. Kerr
Xingzhi Guo
Dan Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1697136

3,413 views

Original Research

Published on 09 Sep 2025

Idiopathic inflammatory myopathy associated with Sjögren’s disease: features of a distinct clinical entity

in Multiple Sclerosis and Neuroimmunology

Franz Felix Konen
Yunus Emre Güzeloglu
Tabea Seeliger
Konstantin Fritz Jendretzky
Sandra Nay
Lea Grote-Levi
Philipp Schwenkenbecher
Christine Gründges
Diana Ernst
Torsten Witte

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654576

3,570 views
2 citations

Original Research

Published on 09 Sep 2025

Anti-neuronal and anti-mitochondrial autoantibodies are associated with lower functional status and more severe respiratory symptoms in post COVID syndrome

in Multiple Sclerosis and Neuroimmunology

Antje Vogelgesang
Anke Steinmetz
Angela Stufano
Valentina Schino
Domenico Plantone
Agnes Flöel
Guglielmo Lucchese

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642250

3,772 views
2 citations

1,511 articles

articles

Combination therapy of ofatumumab and daratumumab in patients with severe anti-NMDA receptor encephalitis

The diagnostic and prognostic value of CXCL13, CXCL10, and CXCL8 in patients with neurosyphilis

The efficacy, safety, and pharmacokinetics/pharmacodynamics of telitacicept following efgartigimod in generalized myasthenia gravis: protocol of a randomized controlled trial

Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040

Polysialic acid restrains inflammatory monocyte maturation

Neutrophils from Alzheimer’s disease mice fail to phagocytose debris and show altered release of immune modulators with age

Immune checkpoint-based biomarkers for therapeutic response in patients with multiple sclerosis

The link between gut microbiota and multiple sclerosis from the perspective of barrier function

Colonization by Akkermansia muciniphila modulates central nervous system autoimmunity in an ecological context-dependent manner

Research on Parkinson’s disease immunotherapy: a bibliometric analysis via multiple databases

Targeting senescent microglia in progressive multiple sclerosis: a geroscience-informed approach

Glycolytic reprogramming during microglial polarization in neurological diseases

Neuroinflammation: targeting microglia for neuroprotection and repair after spinal cord injury

Aging-dependent immunological changes in multiple sclerosis

Exploratory analysis of predictive models in the field of myelitis: a systematic review and meta-analysis

Editorial: Remedying the injured brain in cognitive impairment: potential neuroimmune communication signaling and therapeutic opportunities

Rediscovering parainfectious encephalopathy in the post-COVID-19 era

Morphometric MRI findings in patients with suspected autoimmune psychosis spectrum syndromes and association with EEG slowing, CSF changes, and psychometric/neuropsychological findings

Exploratory study on autoantibodies to arginine-rich human peptides mimicking Epstein-Barr virus in women with post-COVID and myalgic encephalomyelitis/chronic fatigue syndrome

Editorial: Novel CNS targeting molecules, methods, and therapeutics in multiple sclerosis

Human pluripotent stem cell–derived neuronal progenitor cells promote neurogenesis and functional recovery by attenuating neuroinflammation and via extracellular vesicles in a subacute stroke model

Editorial: Bone marrow aging and its impact on immunosenescence in neurological diseases

Idiopathic inflammatory myopathy associated with Sjögren’s disease: features of a distinct clinical entity

Anti-neuronal and anti-mitochondrial autoantibodies are associated with lower functional status and more severe respiratory symptoms in post COVID syndrome