Frontiers in Immunology | NK and Innate Lymphoid Cell Biology

Original Research

Published on 01 Aug 2025

Serum 17β-estradiol inversely correlates with circulating group 2 innate lymphoid cells in a cohort of asthmatic patients

in NK and Innate Lymphoid Cell Biology

Elizabeth J. Myers
Samuel E. Aamodt
Thomas P. Huecksteadt
Robert Paine
Mustafa Mir-Kasimov
Christopher A. Reilly
Sean J. Callahan
Karl A. Sanders
Kristi J. Warren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555228

2,664 views

Original Research

Published on 25 Jul 2025

RAG recombinase expression discriminates the development of natural killer cells

in NK and Innate Lymphoid Cell Biology

Jasmin Sprissler
Ulrich Pannicke
Eva-Maria Rump
Hubert Schrezenmeier
Nicolas Casadei
Michaela Pogoda
Laurence Kuhlburger
Morgana Barroso Oquendo
Stefan Czemmel
Klaus-Michael Debatin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607664

2,435 views

Review

Published on 21 Jul 2025

Unraveling NK cell heterogeneity through single-cell sequencing: insights from physiological and tumor contexts for clinical applications

in NK and Innate Lymphoid Cell Biology

Mingxin Shen
Yutong Liu
Liang Shao
Meng Qu
Shixin Song
Wei Sun
Hao Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612352

4,000 views
1 citation

Review

Published on 11 Jul 2025

CAR-iNKT cells: redefining the frontiers of cellular immunotherapy

in NK and Innate Lymphoid Cell Biology

Magdalena Niedzielska
Amy Chalmers
Martyna C. Popis
Efrat Altman-Sharoni
Stephen Addis
Rebekka Beulen
Nils-Petter Rudqvist
Eleni Chantzoura
Marco A. Purbhoo
Dhan Chand

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625426

7,869 views
2 citations

Correction

Published on 04 Jul 2025

Correction: PM21-particle stimulation augmented with cytokines enhances NK cell expansion and confers memory-like characteristics with enhanced survival

in NK and Innate Lymphoid Cell Biology

Jeremiah L. Oyer
Tayler J. Croom-Perez
Md Faqrul Hasan
Javier A. Rivera-Huertas
Sarah B. Gitto
Joanna M. Mucha
Xiang Zhu
Deborah A. Altomare
Robert Y. Igarashi
Alicja J. Copik

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650274

1,089 views

Mini Review

Published on 26 Jun 2025

Does a natural killer need a CAR?

in NK and Innate Lymphoid Cell Biology

Kangbo Wang
Yumo Zhang
Zhibo Han
Youwei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606126

3,582 views
1 citation

Review

Published on 19 Jun 2025

Designs of NKG2D-based immunotherapeutics for cancer

in NK and Innate Lymphoid Cell Biology

Jianfeng Han
Youwei Wang
Godfrey Chi-Fung Chan
Wing Keung Chan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557644

5,011 views
4 citations

Original Research

Published on 16 Jun 2025

Transcriptomic and proteomic signatures of host NK cells delineate distinct immune states across tuberculosis infection statuses

in NK and Innate Lymphoid Cell Biology

Han Zhang
Liguo Liu
Jie Hu
Xiaolin Wu
Jianhua Zheng
Henan Xin
Jiang Du
Jiarong Yang
Zizheng Lv
Zhuoran Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607770

3,450 views
1 citation

Original Research

Published on 11 Jun 2025

Innate lymphoid cells in bone marrow and peripheral blood of healthy individuals and in bone marrow of patients with myelodysplastic syndromes

in NK and Innate Lymphoid Cell Biology

Laiz C. Bento
Guilherme Martelossi Cebinelli
Nydia Strachman Bacal
Luciana Cavalheiro Marti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568875

2,608 views
1 citation

Original Research

Published on 04 Jun 2025

Impact of a moderate-intensity aerobic exercise intervention on systemic and uterine natural killer cells in women with unexplained recurrent pregnancy loss

in NK and Innate Lymphoid Cell Biology

Aysel Gurbanova
Amber E. M. Lombardi
Denise H. J. Habets
Salwan Al-Nasiry
Marc E. A. Spaanderman
Marien I. de Jonge
Tess Meuleman
Lotte Wieten
Renate G. van der Molen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602939

4,081 views
1 citation

Review

Published on 29 May 2025

Novel strategies to overcome tumor immunotherapy resistance using CAR NK cells

in NK and Innate Lymphoid Cell Biology

Jun-Hui Guo
Ali Afzal
Sadia Ahmad
Ghazala Saeed
Amna Rehman
Umair Ali Khan Saddozai
Lei Liu
Shi-Hao Guo
Xin-Ying Ji
Muhammad Babar Khawar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550652

4,264 views
4 citations

Original Research

Published on 26 May 2025

Construction of stable packaging cell lines for large-scale industrial BaEV-enveloped retroviral vector production

in NK and Innate Lymphoid Cell Biology

Lijun Zhao
Chunting Qiu
Hanyi Chen
Zhuoying Yu
Jiaqi Fan
Qihong Ma
Sijian Zhan
Yaru Feng
Xiaorui Li
Ping Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578660

4,166 views

Review

Published on 23 May 2025

Application and prospects of genetic engineering in CAR-NK cell therapy

in NK and Innate Lymphoid Cell Biology

Caidong Hu
Wenhong Lai
Bin Tian
Xi Xu
Shuiling Xie
Wenting Zhong
Huiqiang Kang
Xiaoyun Chen
Hailiang Li
Jingxin Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600411

4,857 views
3 citations

Original Research

Published on 15 May 2025

Single cell atlas of canine natural killer cells identifies distinct circulating and tissue resident gene profiles

in NK and Innate Lymphoid Cell Biology

Aryana M. Razmara
Marshall Lammers
Sean J. Judge
William J. Murphy
Cameron E. Gaskill
William T.N. Culp
Alicia A. Gingrich
Zachary S. Morris
Robert B. Rebhun
C. Titus Brown

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571085

4,161 views
5 citations

Original Research

Published on 13 May 2025

Functional screening of somatic mutant events in extranodal natural killer/T-cell lymphoma with adrenal involvement

in NK and Innate Lymphoid Cell Biology

Luxin Zhang
Haifeng Gao
Shuang Ma
Xiaoming Fan
Huahang Guo
Man Sun
Shuang Wen
Tianqing Liu
Guanghai Yu
Xiaoying Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566794

3,522 views
1 citation

Review

Published on 05 May 2025

Nanomaterial assisted natural killer cell therapy

in NK and Innate Lymphoid Cell Biology

Xuan Yu
Xiaobo Chen
Yanlong Yang
Yingsong Tian
Jie Jia
Xinghe Tong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1558701

3,934 views

Review

Published on 07 Apr 2025

CAR-NK cell therapy: promise and challenges in solid tumors

in NK and Innate Lymphoid Cell Biology

Sahar Balkhi
Gaia Zuccolotto
Anna Di Spirito
Antonio Rosato
Lorenzo Mortara

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574742

15,937 views
24 citations

Review

Published on 01 Apr 2025

The role of ILC2s in asthma combined with atopic dermatitis: bridging the gap from research to clinical practice

in NK and Innate Lymphoid Cell Biology

Yan-fang Luo
Yu Deng
Feng Yang
Meiduosiji
Xia Xiong
Yu-lai Yuan
Su-hua Ao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567817

4,394 views
1 citation

Original Research

Published on 10 Mar 2025

Association of overweight/obesity and insulin resistance with activation of circulating innate lymphoid cells in women after gestational diabetes mellitus

in NK and Innate Lymphoid Cell Biology

Julia Sbierski-Kind
Stephan Schlickeiser
Lorenzo Semeia
Saori Harada
Eleni Pappa
Javier Villamizar Cujar
Minh-Thuy Katschke
Christina Gar
Andreas Lechner
Andreas L. Birkenfeld

Frontiers in Immunology

doi 10.3389/fimmu.2025.1559326

2,971 views

Original Research

Published on 06 Mar 2025

An intraepithelial ILC1-like natural killer cell subset produces IL-13

in NK and Innate Lymphoid Cell Biology

Sainiteesh Maddineni
Krishna Sharma
Imran A. Mohammad
Alistaire D. Ruggiero-Sherman
Ivan Stepanek
June Ho Shin
Jennifer K. Bando
John B. Sunwoo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1521086

3,760 views
1 citation

Original Research

Published on 20 Feb 2025

Modeling human natural killer cell development and drug response in a microfluidic bone marrow model

in NK and Innate Lymphoid Cell Biology

Leopold Koenig
Inbal Ben-Eliezer
Thi Phuong Tao
Annika Winter
Moran Grossman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1499397

5,093 views
2 citations

Original Research

Published on 20 Feb 2025

Feeder-cell-free system for ex vivo production of natural killer cells from cord blood hematopoietic stem and progenitor cells

in NK and Innate Lymphoid Cell Biology

Marta Martin Corredera
Juliette Paillet
Pierre Gaudeaux
Tifanie Blein
Hanem Sadek
Pauline Rault
Asma Berriche
Jeanne Roche-Naude
Chantal Lagresle-Peyrou
Tayebeh-Shabi Soheili

Frontiers in Immunology

doi 10.3389/fimmu.2025.1531736

6,322 views
3 citations

Original Research

Published on 19 Feb 2025

CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity

in NK and Innate Lymphoid Cell Biology

Camille Rey
Katherine L. Jones
Kevin B. Stacey
Alicia Evans
Jonathan D. Worboys
Gareth Howell
Sam Sheppard
Daniel M. Davis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526379

7,139 views
3 citations

Review

Published on 18 Feb 2025

Can invariant Natural Killer T cells drive B cell fate? a look at the humoral response

in NK and Innate Lymphoid Cell Biology

Pablo A. Palacios
Álvaro Santibañez
Fernanda Aguirre-Muñoz
Cristián Gutiérrez-Vera
Valentina Niño de Zepeda-Carrizo
Martín Góngora-Pimentel
Marioly Müller
Mónica Cáceres
Alexis M. Kalergis
Leandro J. Carreño

Frontiers in Immunology

doi 10.3389/fimmu.2025.1505883

4,143 views
2 citations

824 articles

articles

Serum 17β-estradiol inversely correlates with circulating group 2 innate lymphoid cells in a cohort of asthmatic patients

RAG recombinase expression discriminates the development of natural killer cells

Unraveling NK cell heterogeneity through single-cell sequencing: insights from physiological and tumor contexts for clinical applications

CAR-iNKT cells: redefining the frontiers of cellular immunotherapy

Correction: PM21-particle stimulation augmented with cytokines enhances NK cell expansion and confers memory-like characteristics with enhanced survival

Does a natural killer need a CAR?

Designs of NKG2D-based immunotherapeutics for cancer

Transcriptomic and proteomic signatures of host NK cells delineate distinct immune states across tuberculosis infection statuses

Innate lymphoid cells in bone marrow and peripheral blood of healthy individuals and in bone marrow of patients with myelodysplastic syndromes

Impact of a moderate-intensity aerobic exercise intervention on systemic and uterine natural killer cells in women with unexplained recurrent pregnancy loss

Novel strategies to overcome tumor immunotherapy resistance using CAR NK cells

Construction of stable packaging cell lines for large-scale industrial BaEV-enveloped retroviral vector production

Application and prospects of genetic engineering in CAR-NK cell therapy

Single cell atlas of canine natural killer cells identifies distinct circulating and tissue resident gene profiles

Functional screening of somatic mutant events in extranodal natural killer/T-cell lymphoma with adrenal involvement

Nanomaterial assisted natural killer cell therapy

CAR-NK cell therapy: promise and challenges in solid tumors

The role of ILC2s in asthma combined with atopic dermatitis: bridging the gap from research to clinical practice

Association of overweight/obesity and insulin resistance with activation of circulating innate lymphoid cells in women after gestational diabetes mellitus

An intraepithelial ILC1-like natural killer cell subset produces IL-13

Modeling human natural killer cell development and drug response in a microfluidic bone marrow model

Feeder-cell-free system for ex vivo production of natural killer cells from cord blood hematopoietic stem and progenitor cells

CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity

Can invariant Natural Killer T cells drive B cell fate? a look at the humoral response