Frontiers in Immunology | Parasite Immunology

Original Research

Accepted on 26 Jun 2025

Red pulp macrophages clear parasites, while marginal metallophilic and marginal zone macrophages support CD4 + T cell activation during Plasmodium yoelii infection

in Parasite Immunology

Julia Falkenstein
Anne Ninnemann
Matthias Hose
Abdelrahman Elwy
Karl Lang
Kai Matuschewski
Jan Buer
Astrid M Westendorf
Wiebke Hansen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607201

127 views

Original Research

Accepted on 26 Jun 2025

Hyperglycemia Enhances Group B Streptococcus Pathogenicity by Impairing TLR2 Expression and Chemotactic Response in the Human Placenta

in Parasite Immunology

Rodrigo Jiménez-Escutia
Arumi Villafuerte-Pérez
Donovan Vargas-Alcantar
Karina Martínez-Garfias
Samara Rodríguez-Flores
Pilar Velázquez-Sánchez
Amaury Fortanel-Fonseca
Rodrigo Zamora-Escudero
Marcela Islas-López
Ismael Mancilla-Herrera

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610381

Original Research

Published on 26 Jun 2025

Vaccine-induced responses to R21/Matrix-M – an analysis of samples from a phase 1b age de-escalation, dose-escalation trial

in Parasite Immunology

Caroline Bundi
Duncan Bellamy
Elizabeth Kibwana
Lydia Nyamako
Rodney Ogwang
Kelvias Keter
Domtila Kimani
Ahmed M. Salman
Samuel Provstgaard-Morys
Lisa Stockdale

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620366

625 views

Original Research

Accepted on 24 Jun 2025

Exploring the P. falciparum antigens associated with reduced risk of malaria in pregnancy

in Parasite Immunology

Lucy Mwai
Sebastian Musundi
Harrison Waweru
Hikaru Nagaoka
Takafumi Tsuboi
Eizo Takashima
Jesse Gitaka
Bernard N. Kanoi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622435

155 views

Original Research

Published on 24 Jun 2025

Dual single-cell and bulk RNA sequencing reveal transcriptional profiles underlying heterogenous host-parasite interactions in human peripheral blood mononuclear cells

in Parasite Immunology

Praveena Chandrasegaran
Bekir Faydaci
Barbara Shih
Musa A. Hassan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1582645

528 views

Original Research

Accepted on 23 Jun 2025

Evaluation of the immunoprotective potential of recombinant EtMIF as a subunit vaccine candidate against Eimeria tenella infection in chickens

in Parasite Immunology

Rui Bai
Wang Hui
Jiale Guo
Yang Pei
Yongbin Li
Shuying Zhu
Chenyang Lv
Jianhui Li
Xiaozhen Cui
Xiaoling Lv

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623743

Original Research

Published on 23 Jun 2025

PLGA nanoparticles as an efficient carrier in Toxoplasma GAP45: a more effective vaccine against acute toxoplasmosis than traditional ones

in Parasite Immunology

Pan Zhou
YanLi Yu
WeiYu Qi
XiaoJuan Wang
YouLi Yu
JianDong Wang
Li Zhang
ZhengQing Yu
TingLi Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600399

333 views

Original Research

Published on 20 Jun 2025

Splenic macrophage functional profile and its role in the immunopathogenesis of canine visceral leishmaniasis

in Parasite Immunology

Tainã Luís de Souza
Marta de Almeida Santiago
Francini Neves Ribeiro
Fabiano Borges Figueiredo
Artur Augusto Velho Mendes Junior
Rodrigo Caldas Menezes
Renato Porrozzi
Fernanda Nazaré Morgado

Frontiers in Immunology

doi 10.3389/fimmu.2025.1617751

511 views

Original Research

Accepted on 18 Jun 2025

Amblyostatin-1, the first salivary cystatin with host immunomodulatory and anti-inflammatory properties from the Neotropical tick Amblyomma sculptum, vector of Brazilian spotted fever

in Parasite Immunology

Wilson Santos Molari
Mohamed Amine Jmel
Josiane Betim de Assis
Alan Frazão Silva
Júlia de Moura Bernardi
Gretta Huamanrayme Bustamante
José María Medina
Eliane Esteves
Solange Antão Antão
Andréa Cristina Fogaça

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585703

110 views

Original Research

Accepted on 18 Jun 2025

Development of high affinity antibodies to Plasmodium falciparum merozoite and sporozoite antigens during infancy and adulthood

in Parasite Immunology

Allan Lugaajju
Richard Idro
Stephen Kiwuwa
James G Beeson
Damien R Drew
Susanne E Mortazavi
Sara Linse
Kristina E M Persson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1562671

134 views

Original Research

Accepted on 17 Jun 2025

R21/Matrix-M Malaria Vaccine Drives Diverse Immune Responses in Pre-Exposed Adults: Insights from a Phase IIb Controlled Human Malaria Infection Trial

in Parasite Immunology

Elizabeth Kibwana
Caroline Bundi
Domtila KIMANI
Lydia Nyamako
Kelvias Keter
Agnes Mutiso
Rodney Ogwang
Duncan Bellamy
Katerina Rapi
Amelia Bajer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620365

210 views

Original Research

Published on 17 Jun 2025

Interferons and Toxoplasma gondii shape PD-L1 regulation in retinal barrier cells: the critical role of proteases

in Parasite Immunology

Benjamin Geiller
Camila Cevallos
Iuliia Tsybenko
Lydia Arnoux
Marie-Paule Felder-Schmittbuhl
Alexander W. Pfaff

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607247

573 views

Original Research

Accepted on 13 Jun 2025

Non-additive strong gene interactions cause striking differences in organ pathology and cytokine response in leishmaniasis

in Parasite Immunology

Yahya Sohrabi
Tatyana Kobets
Valeriya Volkova
Eliska Javorkova
Imtissal Krayem
Alena Zajicova
Helena Havelkova
Milena Svobodova
Vladimir Holan
Peter Demant

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579257

173 views

Original Research

Accepted on 10 Jun 2025

Mice Mucosal Leishmaniasis model shown high parasite load, increased cytotoxicity and impaired IL-10 + T cell response

in Parasite Immunology

Alisson Amaral Da-Rocha
Julio Souza Dos-Santos
Igor Santos Bittencourt
Douglas Barroso De-Almeida
Naiara Carla Santos Manhaes
Hozany Praxedes
Joao Victor Paiva Romano
Elias Barbosa Silva-Junior
Antonio Jose Silva-Goncalves
Marcia Pereira L Oliveira

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621781

175 views

Original Research

Published on 09 Jun 2025

Dual roles of Anisakis pegreffii proteins in macrophage immune dynamics

in Parasite Immunology

Min-hao Zeng
Sarah Alsobaie
Xiao-xu Wang
Shan Li
Fahad M. Aldakheel
Mourad A. M. Aboul-Soud
Wei-bin Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595093

999 views

General Commentary

Published on 09 Jun 2025

Commentary: Induction of hepatic fibrosis in mice with schistosomiasis by extracellular microRNA-30 derived from Schistosoma japonicum eggs

in Parasite Immunology

Haoran Zhong
Yamei Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604905

798 views