Frontiers in Immunology | Primary Immunodeficiencies

Original Research

Published on 10 Mar 2022

Impact of Hypogammaglobulinemia on the Course of COVID-19 in a Non-Intensive Care Setting: A Single-Center Retrospective Cohort Study

in Primary Immunodeficiencies

Riccardo Scarpa
Alessandro Dell’Edera
Carla Felice
Roberta Buso
Francesco Muscianisi
Renato Finco Gambier
Sara Toffolo
Ugo Grossi
Mario Giobbia
Giuseppina Barberio

Frontiers in Immunology

doi 10.3389/fimmu.2022.842643

6,381 views
12 citations

Original Research

Published on 10 Mar 2022

SARS-CoV-2 T Cell Response in Severe and Fatal COVID-19 in Primary Antibody Deficiency Patients Without Specific Humoral Immunity

in Primary Immunodeficiencies

Sophie Steiner
Tatjana Schwarz
Victor M. Corman
Laura Gebert
Malte C. Kleinschmidt
Alexandra Wald
Sven Gläser
Jan M. Kruse
Daniel Zickler
Alexander Peric

Frontiers in Immunology

doi 10.3389/fimmu.2022.840126

7,281 views
26 citations

Systematic Review

Published on 09 Mar 2022

Functional and Immune Modulatory Characteristics of Bone Marrow Mesenchymal Stromal Cells in Patients With Aplastic Anemia: A Systematic Review

in Primary Immunodeficiencies

Khaled Atmar
Adam J. Tulling
Arjan C. Lankester
Marije Bartels
Frans J. Smiers
Mirjam van der Burg
Alexander B. Mohseny

Frontiers in Immunology

doi 10.3389/fimmu.2022.859668

4,673 views
7 citations

Original Research

Published on 28 Feb 2022

Risk Factors for Severe COVID-19 and Hospital Admission in Patients With Inborn Errors of Immunity - Results From a Multicenter Nationwide Study

in Primary Immunodeficiencies

Tomas Milota
Marta Sobotkova
Jitka Smetanova
Marketa Bloomfield
Jana Vydlakova
Zita Chovancova
Jiri Litzman
Roman Hakl
Jiri Novak
Ivana Malkusova

Frontiers in Immunology

doi 10.3389/fimmu.2022.835770

5,452 views
31 citations

Original Research

Published on 23 Feb 2022

Integrating Clinics, Laboratory, and Imaging for the Diagnosis of Common Variable Immunodeficiency-Related Granulomatous–Lymphocytic Interstitial Lung Disease

in Primary Immunodeficiencies

Marta Dafne Cabanero-Navalon
Victor Garcia-Bustos
Leonardo Fabio Forero-Naranjo
Eduardo José Baettig-Arriagada
María Núñez-Beltrán
Antonio José Cañada-Martínez
Maria José Forner Giner
Nelly Catalán-Cáceres
Manuela Martínez Francés
Pedro Moral Moral

Frontiers in Immunology

doi 10.3389/fimmu.2022.813491

4,336 views
18 citations

Case Report

Published on 23 Feb 2022

Case Report: Rotavirus Vaccination and Severe Combined Immunodeficiency in Japan

in Primary Immunodeficiencies

Kay Tanita
Yoshiki Kawamura
Hiroki Miura
Noriko Mitsuiki
Takahiro Tomoda
Kento Inoue
Akihiro Iguchi
Masafumi Yamada
Taro Yoshida
Hideki Muramatsu

Frontiers in Immunology

doi 10.3389/fimmu.2022.786375

5,400 views
4 citations

Original Research

Published on 22 Feb 2022

Inborn Errors of Immunity Associated With Type 2 Inflammation in the USIDNET Registry

in Primary Immunodeficiencies

Kelsey L. Smith
Darlene Dai
Bhavi P. Modi
Rahnuma Sara
Elizabeth Garabedian
Rebecca A. Marsh
Jennifer Puck
Elizabeth Secord
Kathleen E. Sullivan
Stuart E. Turvey

Frontiers in Immunology

doi 10.3389/fimmu.2022.831279

4,049 views
9 citations

Original Research

Published on 21 Feb 2022

Pediatric Prediction Model for Low Immunoglobulin G Level Based on Serum Globulin and Illness Status

in Primary Immunodeficiencies

Narissara Suratannon
Phimphika Tantithummawong
Cameron Paul Hurst
Yuda Chongpison
Jongkonnee Wongpiyabovorn
P. Martin van Hagen
Willem A. Dik
Pantipa Chatchatee

Frontiers in Immunology

doi 10.3389/fimmu.2022.825867

5,223 views
3 citations

Original Research

Published on 21 Feb 2022

IL-17-Dependent Dysregulated Cutaneous Immune Homeostasis in the Absence of the Wiskott–Aldrich Syndrome Protein

in Primary Immunodeficiencies

Katherine E. Herman
Takeshi Yoshida
Angela Hughson
Alex Grier
Steven R. Gill
Lisa A. Beck
Deborah J. Fowell

Frontiers in Immunology

doi 10.3389/fimmu.2022.817427

3,625 views
4 citations

Original Research

Published on 17 Feb 2022

Common Variable Immunodeficiency-Associated Cancers: The Role of Clinical Phenotypes, Immunological and Genetic Factors

in Primary Immunodeficiencies

Luzia Bruns
Victoria Panagiota
Sandra von Hardenberg
Gunnar Schmidt
Ignatius Ryan Adriawan
Eleni Sogka
Stefanie Hirsch
Gerrit Ahrenstorf
Torsten Witte
Reinhold Ernst Schmidt

Frontiers in Immunology

doi 10.3389/fimmu.2022.742530

11,942 views
23 citations

Case Report

Published on 15 Feb 2022

Case Report: Cytomegalovirus Disease Is an Under-Recognized Contributor to Morbidity and Mortality in Common Variable Immunodeficiency

in Primary Immunodeficiencies

Samantha Chan
Jack Godsell
Miles Horton
Anthony Farchione
Lauren J. Howson
Mai Margetts
Celina Jin
Josh Chatelier
Michelle Yong
Joseph Sasadeusz

Frontiers in Immunology

doi 10.3389/fimmu.2022.815193

5,200 views
9 citations

Original Research

Published on 14 Feb 2022

Antigen-Specific CD4+ T-Cell Activation in Primary Antibody Deficiency After BNT162b2 mRNA COVID-19 Vaccination

in Primary Immunodeficiencies

Kai M. T. Sauerwein
Christoph B. Geier
Roman F. Stemberger
Hüseyin Akyaman
Peter Illes
Michael B. Fischer
Martha M. Eibl
Jolan E. Walter
Hermann M. Wolf

Frontiers in Immunology

doi 10.3389/fimmu.2022.827048

5,971 views
20 citations

Original Research

Published on 10 Feb 2022

AKT Hyperphosphorylation and T Cell Exhaustion in Down Syndrome

in Primary Immunodeficiencies

Daphne Peeters
Ingrid Pico-Knijnenburg
Douwe Wieringa
Mandana Rad
Roos Cuperus
Madelon Ruige
Frank Froeling
Gerda W. Zijp
Mirjam van der Burg
Gertjan J. A. Driessen

Frontiers in Immunology

doi 10.3389/fimmu.2022.724436

4,165 views
6 citations

Original Research

Published on 08 Feb 2022

Myeloperoxidase Deficiency Alters the Process of the Regulated Cell Death of Polymorphonuclear Neutrophils

in Primary Immunodeficiencies

Silvie Kremserová
Anna Kocurková
Michaela Chorvátová
Anna Klinke
Lukáš Kubala

Frontiers in Immunology

doi 10.3389/fimmu.2022.707085

4,036 views
7 citations

Original Research

Published on 04 Feb 2022

Hyper IgE Syndrome in an Isolated Population in Israel

in Primary Immunodeficiencies

Idit Lachover-Roth
Irina Lagovsky
Atalia Shtorch-Asor
Ronit Confino-Cohen
Eyal Reinstein
Ben-Zion Garty

Frontiers in Immunology

doi 10.3389/fimmu.2022.829239

2,283 views
2 citations

Original Research

Published on 04 Feb 2022

Primary Immune Deficiency: Patients’ Preferences for Replacement Immunoglobulin Therapy

in Primary Immunodeficiencies

Juan Marcos Gonzalez
Mark Ballow
Angelyn Fairchild
Michael Chris Runken

Frontiers in Immunology

doi 10.3389/fimmu.2022.827305

5,878 views
11 citations