Frontiers in Immunology | Systems Immunology

Original Research

Published on 04 Feb 2025

Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers

in Systems Immunology

Ruohua Li
Cuixia Zhou
Kejun Ye
Haihui Chen
Mengjia Peng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1496046

206 views

Original Research

Accepted on 03 Feb 2025

Clinical Application of Myxovirus Resistance Protein A as a Diagnostic Biomarker to Differentiate Viral and Bacterial Respiratory Infections in Pediatric Patients

in Systems Immunology

Min Zhu
Lijin Chen
Jiali Cao
Jianguo Cai
Shuying Huang
Huibin Wang
Huanjuan He
Zimin Chen
Rongfu Huang
Huiming Ye

Frontiers in Immunology

doi 10.3389/fimmu.2025.1540675

Methods

Accepted on 03 Feb 2025

OnmiMHC: A Machine Learning Solution for UCEC Tumor Vaccine Development through Enhanced Peptide-MHC Binding Prediction

in Systems Immunology

Fangfang Jian
Haihua Cai
Qushuo Chen
Xiaoyong Pan
Weiwei Feng
Ye Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550252

119 views

Original Research

Accepted on 03 Feb 2025

In-depth immunochemical characterization of the serum antibody response using a dual-titration microspot assay

in Systems Immunology

Ágnes Kovács
Zoltán Hérincs
Krisztian Papp
Jakub Zbigniew Kaczmarek
Daniel Nyberg Larsen
Pernille Stage
László Bereczki
Eszter Ujhelyi
Tamás Pfeil
József Prechl

Frontiers in Immunology

doi 10.3389/fimmu.2025.1494624

Hypothesis and Theory

Accepted on 30 Jan 2025

Unique Gating Strategy Identifier based on the Prime Population System and Gödel Numbers

in Systems Immunology

Antonio Cosma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1481412

Systematic Review

Accepted on 28 Jan 2025

Research trends of inflammation in autism spectrum disorders: a bibliometric analysis

in Systems Immunology

Yajing Chen
Xiaohuan Du
Xianming Zhang
Fang Li
Shuwei Yuan
Wenjing Wang
Zengyan Zhu
Mei Wang
Chao Gu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534660

Original Research

Published on 23 Jan 2025

Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning

in Systems Immunology

Tao Zhou
Can Zhu
Wei Zhang
Qiongfang Wu
Mingqiang Deng
Zhiwei Jiang
Longfei Peng
Hao Geng
Zhouting Tuo
Ci Zou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1511529

260 views

Original Research

Published on 23 Jan 2025

Feature selection enhances peptide binding predictions for TCR-specific interactions

in Systems Immunology

Hamid Teimouri
Zahra S. Ghoreyshi
Anatoly B. Kolomeisky
Jason T. George

Frontiers in Immunology

doi 10.3389/fimmu.2024.1510435

453 views

Original Research

Published on 23 Jan 2025

Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia

in Systems Immunology

Rong Lin
XiaoYing Weng
Liang Lin
XuYang Hu
ZhiYan Liu
Jing Zheng
FenFang Shen
Rui Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1453633

355 views

Original Research

Published on 20 Jan 2025

Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion in astronauts’ blood cells in space

in Systems Immunology

Maria Moreno-Villanueva
Luis E. Jimenez-Chavez
Stephanie Krieger
Liang-Hao Ding
Ye Zhang
Adriana Babiak-Vazquez
Mark Berres
Sandra Splinter
Kristen E. Pauken
Brian C. Schaefer

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512578

962 views

Original Research

Published on 20 Jan 2025

Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1–infected women is associated with lower viral loads

in Systems Immunology

Elina El-Badry
Luxiao Chen
Khader Ghneim
Ziyi Li
Kelsie Brooks
Jake Rhodes
Rafick Sekaly
William Kilembe
Susan Allen
Hao Wu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1507530

427 views

Original Research

Published on 14 Jan 2025

Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anti-citrullinated peptide antibody-positive early rheumatoid arthritis

in Systems Immunology

Bong-Ki Hong
Sungyong You
Jung Gon Kim
Minhyung Kim
Naeun Lee
Kijun Lee
In-Pyo Baek
Ji Hyeon Ju
Wan-Uk Kim
Ho-Youn Kim

Frontiers in Immunology

doi 10.3389/fimmu.2024.1439082

578 views

Original Research

Published on 14 Jan 2025

Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets

in Systems Immunology

Huahua Li
Lingling Zou
Zhaowei Long
Junkun Zhan

Frontiers in Immunology

doi 10.3389/fimmu.2024.1537909

544 views

Original Research

Published on 14 Jan 2025

Network pharmacology and multi-omics validation of the Jianpi-Yishen formula in the treatment of chronic kidney disease

in Systems Immunology

Yuyan Li
Yueming Luo
Yilan Hu
Siting Li
Guandong Li
Wanyangchuan Zhang
Xiufen Gu
Jianting Wang
Shunmin Li
Hong Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512519

450 views

Original Research

Published on 13 Jan 2025

Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective

in Systems Immunology

Didar Murad
Rehan Zafar Paracha
Maryum Nisar

Frontiers in Immunology

doi 10.3389/fimmu.2024.1457324

847 views

Original Research

Published on 13 Jan 2025

Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks

in Systems Immunology

Dakota N. Paine
Meghan Hermance
Saravanan Thangamani

Frontiers in Immunology

doi 10.3389/fimmu.2024.1511132

514 views

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Articles

Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers

Clinical Application of Myxovirus Resistance Protein A as a Diagnostic Biomarker to Differentiate Viral and Bacterial Respiratory Infections in Pediatric Patients

OnmiMHC: A Machine Learning Solution for UCEC Tumor Vaccine Development through Enhanced Peptide-MHC Binding Prediction

In-depth immunochemical characterization of the serum antibody response using a dual-titration microspot assay

Unique Gating Strategy Identifier based on the Prime Population System and Gödel Numbers

Research trends of inflammation in autism spectrum disorders: a bibliometric analysis

Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning

Feature selection enhances peptide binding predictions for TCR-specific interactions

Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia

Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion in astronauts’ blood cells in space

Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1–infected women is associated with lower viral loads

Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anti-citrullinated peptide antibody-positive early rheumatoid arthritis

Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets

Network pharmacology and multi-omics validation of the Jianpi-Yishen formula in the treatment of chronic kidney disease

Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective

Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks