Frontiers in Immunology | Systems Immunology

Original Research

Published on 27 Jun 2024

Identification of immune-related genes and small-molecule drugs in hypertension-induced left ventricular hypertrophy based on machine learning algorithms and molecular docking

in Systems Immunology

Mingxuan Zhou
Tiegang Li
Silin Lv
Wenqiang Gan
Fang Zhang
Yuexia Che
Liu Yang
Yufang Hou
Zheng Yan
Zifan Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1351945

5,598 views
5 citations

Original Research

Published on 25 Jun 2024

Using adjusted local assortativity with Molecular Pixelation unveils colocalization of membrane proteins with immunological significance

in Systems Immunology

Jan Rhomberg-Kauert
Max Karlsson
Divya Thiagarajan
Tomasz Kallas
Filip Karlsson
Simon Fredriksson
Johan Dahlberg
Alvaro Martinez Barrio

Frontiers in Immunology

doi 10.3389/fimmu.2024.1309916

3,329 views

Original Research

Published on 25 Jun 2024

Coordinated inflammation and immune response transcriptional regulation in breast cancer molecular subtypes

in Systems Immunology

Tadeo Enrique Velazquez-Caldelas
Jose Maria Zamora-Fuentes
Enrique Hernandez-Lemus

Frontiers in Immunology

doi 10.3389/fimmu.2024.1357726

3,719 views
2 citations

Original Research

Published on 21 Jun 2024

Generation of functionally active resident macrophages from adipose tissue by 3D cultures

in Systems Immunology

Adèle Arlat
Marie-Laure Renoud
Jean Nakhle
Miguel Thomas
Jessica Fontaine
Emmanuelle Arnaud
Cédric Dray
Hélène Authier
Paul Monsarrat
Agnès Coste

Frontiers in Immunology

doi 10.3389/fimmu.2024.1356397

3,921 views
2 citations

Original Research

Published on 20 Jun 2024

IgG4-related disease with nasopharyngeal malignancy-like manifestations

in Systems Immunology

Xijun Lin
Peiliang Lin
Jianming Fan
Biying Zhang
Faya Liang
Ping Han
Xiang Liu
Xiaoming Huang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1322159

4,742 views
1 citation

Editorial

Published on 18 Jun 2024

Editorial: Artificial intelligence in predicting, determining and controlling cell phenotype or tissue function in inflammatory diseases

in Systems Immunology

Melanie L. Hart
Ryuji Kato
Bernd Rolauffs

Frontiers in Immunology

doi 10.3389/fimmu.2024.1443534

2,640 views
4 citations

Original Research

Published on 17 Jun 2024

An in vitro model system for testing chemical effects on microbiome-immune interactions – examples with BPX and PFAS mixtures

in Systems Immunology

Florence Fischer
Arkadiusz Pierzchalski
Sarah Riesbeck
Alix Sarah Aldehoff
Victor Alfonso Castaneda-Monsalve
Sven-Bastiaan Haange
Martin von Bergen
Ulrike Elisabeth Rolle-Kampczyk
Nico Jehmlich
Ana Claudia Zenclussen

Frontiers in Immunology

doi 10.3389/fimmu.2024.1298971

6,129 views
1 citation

Original Research

Published on 14 Jun 2024

Identification and experimental validation of cuproptosis regulatory program in a sepsis immune microenvironment through a combination of single-cell and bulk RNA sequencing

in Systems Immunology

Tingru Zhao
Yan Guo
Jin Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1336839

5,838 views
4 citations

Original Research

Published on 10 Jun 2024

From proteome to candidate vaccines: target discovery and molecular dynamics-guided multi-epitope vaccine engineering against kissing bug

in Systems Immunology

Faisal F. Albaqami
Ali Altharawi
Hassan N. Althurwi
Khalid M. Alharthy

Frontiers in Immunology

doi 10.3389/fimmu.2024.1413893

3,684 views
1 citation

Original Research

Published on 06 Jun 2024

SWIFT clustering analysis of intracellular cytokine staining flow cytometry data of the HVTN 105 vaccine trial reveals high frequencies of HIV-specific CD4+ T cell responses and associations with humoral responses

in Systems Immunology

Tim R. Mosmann
Jonathan A. Rebhahn
Stephen C. De Rosa
Michael C. Keefer
M. Juliana McElrath
Nadine G. Rouphael
Giuseppe Pantaleo
Peter B. Gilbert
Lawrence Corey
James J. Kobie

Frontiers in Immunology

doi 10.3389/fimmu.2024.1347926

2,814 views
1 citation

Original Research

Published on 03 Jun 2024

Causality of genetically proxied immunophenotypes on cardiovascular diseases: a Mendelian randomization study

in Systems Immunology

Xuehan Wang
Huixin Cheng
Meng Feng
Bing Jiang
Chunzhen Ren
Qilin Chen
Xiaodong Zhi
Yingdong Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1344773

4,452 views
10 citations

Original Research

Published on 30 May 2024

A multiscale spatial modeling framework for the germinal center response

in Systems Immunology

Derek P. Mu
Christopher D. Scharer
Norbert E. Kaminski
Qiang Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1377303

7,152 views
1 citation

Original Research

Published on 28 May 2024

Dissecting causal relationships between immune cells, plasma metabolites, and COPD: a mediating Mendelian randomization study

in Systems Immunology

Zhenghua Cao
Tong Wu
Yakun Fang
Feng Sun
Huan Ding
Lingling Zhao
Li Shi

Frontiers in Immunology

doi 10.3389/fimmu.2024.1406234

12,803 views
16 citations

Review

Published on 21 May 2024

In vitro immunity: an overview of immunocompetent organ-on-chip models

in Systems Immunology

Andrew I. Morrison
Mirthe J. Sjoerds
Leander A. Vonk
Susan Gibbs
Jasper J. Koning

Frontiers in Immunology

doi 10.3389/fimmu.2024.1373186

14,801 views
31 citations

Original Research

Published on 16 May 2024

The molecular landscape of sepsis severity in infants: enhanced coagulation, innate immunity, and T cell repression

in Systems Immunology

Susie Shih Yin Huang
Mohammed Toufiq
Pirooz Eghtesady
Nicholas Van Panhuys
Mathieu Garand

Frontiers in Immunology

doi 10.3389/fimmu.2024.1281111

3,492 views
4 citations

Review

Published on 14 May 2024

Progress in research on the role of fluoride in immune damage

in Systems Immunology

Siqi Zhu
Wei Wei

Frontiers in Immunology

doi 10.3389/fimmu.2024.1394161

8,844 views
15 citations

Original Research

Published on 24 Apr 2024

Unraveling the immunogenetic landscape of autism spectrum disorder: a comprehensive bioinformatics approach

in Systems Immunology

Jieying Ma
Deyang Liu
Jianzhong Zhao
Xiaolu Fang
Dengyin Bu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1347139

4,406 views
2 citations

Review

Published on 23 Apr 2024

Towards early diagnosis of Alzheimer’s disease: advances in immune-related blood biomarkers and computational approaches

in Systems Immunology

Sophia Krix
Ella Wilczynski
Neus Falgàs
Raquel Sánchez-Valle
Eti Yoles
Uri Nevo
Kuti Baruch
Holger Fröhlich

Frontiers in Immunology

doi 10.3389/fimmu.2024.1343900

12,540 views
12 citations

Correction

Published on 16 Apr 2024

Corrigendum: Bioinformatic analysis of related immune cell infiltration and key genes in the progression of osteonecrosis of the femoral head

in Systems Immunology

Xudong Duan
Fangze Xing
Jiewen Zhang
Heng Li
Yang Chen
Yutian Lei
Yiwei Zhao
Ruomu Cao
Huanshuai Guan
Ning Kong

Frontiers in Immunology

doi 10.3389/fimmu.2024.1410267

1,608 views
1 citation

Original Research

Published on 12 Apr 2024

Mendelian randomization and transcriptome analysis identified immune-related biomarkers for osteoarthritis

in Systems Immunology

Wei-Wei Pang
Yi-Sheng Cai
Chong Cao
Fu-Rong Zhang
Qin Zeng
Dan-Yang Liu
Ning Wang
Xiao-Chao Qu
Xiang-Ding Chen
Hong-Wen Deng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1334479

8,294 views
8 citations

Original Research

Published on 08 Apr 2024

Poly I:C elicits broader and stronger humoral and cellular responses to a Plasmodium vivax circumsporozoite protein malaria vaccine than Alhydrogel in mice

in Systems Immunology

Tiffany B. L. Costa-Gouvea
Katia S. Françoso
Rodolfo F. Marques
Alba Marina Gimenez
Ana C. M. Faria
Leonardo M. Cariste
Mariana R. Dominguez
José Ronnie C. Vasconcelos
Helder I. Nakaya
Eduardo L. V. Silveira

Frontiers in Immunology

doi 10.3389/fimmu.2024.1331474

4,810 views
3 citations

Original Research

Published on 03 Apr 2024

Early B cell transcriptomic markers of measles-specific humoral immunity following a 3rd dose of MMR vaccine

in Systems Immunology

Iana H. Haralambieva
Jun Chen
Huy Quang Quach
Tamar Ratishvili
Nathaniel D. Warner
Inna G. Ovsyannikova
Gregory A. Poland
Richard B. Kennedy

Frontiers in Immunology

doi 10.3389/fimmu.2024.1358477

4,561 views
4 citations

Original Research

Published on 02 Apr 2024

Experimental trials of predicted CD4+ and CD8+ T-cell epitopes of respiratory syncytial virus

in Systems Immunology

Syeda Tahira Qousain Naqvi
Syed Aun Muhammad
Jinlei Guo
Sidra Zafar
Amjad Ali
Larry J. Anderson
Christina A. Rostad
Baogang Bai

Frontiers in Immunology

doi 10.3389/fimmu.2024.1349749

5,697 views
3 citations

Original Research

Published on 02 Apr 2024

Transcriptome organization of white blood cells through gene co-expression network analysis in a large RNA-seq dataset

in Systems Immunology

Paola Forabosco
Mauro Pala
Francesca Crobu
Maria Antonietta Diana
Mara Marongiu
Roberto Cusano
Andrea Angius
Maristella Steri
Valeria Orrù
David Schlessinger

Frontiers in Immunology

doi 10.3389/fimmu.2024.1350111

4,087 views
2 citations

542 articles

articles

Identification of immune-related genes and small-molecule drugs in hypertension-induced left ventricular hypertrophy based on machine learning algorithms and molecular docking

Using adjusted local assortativity with Molecular Pixelation unveils colocalization of membrane proteins with immunological significance

Coordinated inflammation and immune response transcriptional regulation in breast cancer molecular subtypes

Generation of functionally active resident macrophages from adipose tissue by 3D cultures

IgG4-related disease with nasopharyngeal malignancy-like manifestations

Editorial: Artificial intelligence in predicting, determining and controlling cell phenotype or tissue function in inflammatory diseases

An in vitro model system for testing chemical effects on microbiome-immune interactions – examples with BPX and PFAS mixtures

Identification and experimental validation of cuproptosis regulatory program in a sepsis immune microenvironment through a combination of single-cell and bulk RNA sequencing

From proteome to candidate vaccines: target discovery and molecular dynamics-guided multi-epitope vaccine engineering against kissing bug

SWIFT clustering analysis of intracellular cytokine staining flow cytometry data of the HVTN 105 vaccine trial reveals high frequencies of HIV-specific CD4+ T cell responses and associations with humoral responses

Causality of genetically proxied immunophenotypes on cardiovascular diseases: a Mendelian randomization study

A multiscale spatial modeling framework for the germinal center response

Dissecting causal relationships between immune cells, plasma metabolites, and COPD: a mediating Mendelian randomization study

In vitro immunity: an overview of immunocompetent organ-on-chip models

The molecular landscape of sepsis severity in infants: enhanced coagulation, innate immunity, and T cell repression

Progress in research on the role of fluoride in immune damage

Unraveling the immunogenetic landscape of autism spectrum disorder: a comprehensive bioinformatics approach

Towards early diagnosis of Alzheimer’s disease: advances in immune-related blood biomarkers and computational approaches

Corrigendum: Bioinformatic analysis of related immune cell infiltration and key genes in the progression of osteonecrosis of the femoral head

Mendelian randomization and transcriptome analysis identified immune-related biomarkers for osteoarthritis

Poly I:C elicits broader and stronger humoral and cellular responses to a Plasmodium vivax circumsporozoite protein malaria vaccine than Alhydrogel in mice

Early B cell transcriptomic markers of measles-specific humoral immunity following a 3rd dose of MMR vaccine

Experimental trials of predicted CD4+ and CD8+ T-cell epitopes of respiratory syncytial virus

Transcriptome organization of white blood cells through gene co-expression network analysis in a large RNA-seq dataset