Frontiers in Immunology | Systems Immunology

Methods

Published on 19 Nov 2021

How to Prepare Spectral Flow Cytometry Datasets for High Dimensional Data Analysis: A Practical Workflow

in Systems Immunology

Hannah den Braanker
Margot Bongenaar
Erik Lubberts

Frontiers in Immunology

doi 10.3389/fimmu.2021.768113

50,245 views
45 citations

Perspective

Published on 16 Nov 2021

Systems Biology to Understand and Regulate Human Retroviral Proinflammatory Response

in Systems Immunology

Mohamed Helmy
Kumar Selvarajoo

Frontiers in Immunology

doi 10.3389/fimmu.2021.736349

6,544 views
11 citations

Technology and Code

Published on 05 Nov 2021

FlowKit: A Python Toolkit for Integrated Manual and Automated Cytometry Analysis Workflows

in Systems Immunology

Scott White
John Quinn
Jennifer Enzor
Janet Staats
Sarah M. Mosier
James Almarode
Thomas N. Denny
Kent J. Weinhold
Guido Ferrari
Cliburn Chan

Frontiers in Immunology

doi 10.3389/fimmu.2021.768541

28,061 views
43 citations

Original Research

Published on 05 Nov 2021

Continuous Modeling of T CD4 Lymphocyte Activation and Function

in Systems Immunology

David Martínez-Méndez
Luis Mendoza
Carlos Villarreal
Leonor Huerta

Frontiers in Immunology

doi 10.3389/fimmu.2021.743559

9,806 views
15 citations

Original Research

Published on 20 Oct 2021

Ductal Macrophages Predominate in the Immune Landscape of the Lactating Mammary Gland

in Systems Immunology

Chervin Hassel
Blandine Gausserès
Laurence Guzylack-Piriou
Gilles Foucras

Frontiers in Immunology

doi 10.3389/fimmu.2021.754661

8,155 views
25 citations

Original Research

Published on 20 Oct 2021

FUCA2 Is a Prognostic Biomarker and Correlated With an Immunosuppressive Microenvironment in Pan-Cancer

in Systems Immunology

Anyuan Zhong
Ting Chen
Yufei Xing
Xue Pan
Minhua Shi

Frontiers in Immunology

doi 10.3389/fimmu.2021.758648

14,151 views
23 citations

Original Research

Published on 19 Oct 2021

N6-Methyladenosine Methylomic Landscape of Lung Tissues in Murine Acute Allergic Asthma

in Systems Immunology

Fangzhou Teng
Weifeng Tang
Tulake Wuniqiemu
Jingjing Qin
Yaolong Zhou
Xi Huang
Shiyuan Wang
Xueyi Zhu
Zhao Tang
La Yi

Frontiers in Immunology

doi 10.3389/fimmu.2021.740571

7,527 views
22 citations

Original Research

Published on 15 Oct 2021

Mapping Pulmonary and Systemic Inflammation in Preschool Aged Children With Cystic Fibrosis

in Systems Immunology

Shivanthan Shanthikumar
Sarath C. Ranganathan
Richard Saffery
Melanie R. Neeland

Frontiers in Immunology

doi 10.3389/fimmu.2021.733217

4,943 views
15 citations

Original Research

Published on 13 Oct 2021

Immune Response in Severe and Non-Severe Coronavirus Disease 2019 (COVID-19) Infection: A Mechanistic Landscape

in Systems Immunology

Kavitha Mukund
Priya Nayak
Chethan Ashokkumar
Sohail Rao
Jose Almeda
Monica M. Betancourt-Garcia
Rakesh Sindhi
Shankar Subramaniam

Frontiers in Immunology

doi 10.3389/fimmu.2021.738073

13,637 views
44 citations

Original Research

Published on 07 Oct 2021

Determinants of Ligand Specificity and Functional Plasticity in Type I Interferon Signaling

in Systems Immunology

Duncan Kirby
Baljyot Parmar
Sepehr Fathi
Sagar Marwah
Chitra R. Nayak
Vera Cherepanov
Sonya MacParland
Jordan J. Feld
Grégoire Altan-Bonnet
Anton Zilman

Frontiers in Immunology

doi 10.3389/fimmu.2021.748423

5,897 views
9 citations

Hypothesis and Theory

Published on 20 Sep 2021

System-Level Scenarios for the Elucidation of T Cell-Mediated Germinal Center B Cell Differentiation

in Systems Immunology

Niels J. M. Verstegen
Victor Ubels
Hans V. Westerhoff
S. Marieke van Ham
Matteo Barberis

Frontiers in Immunology

doi 10.3389/fimmu.2021.734282

8,524 views
23 citations

Original Research

Published on 16 Sep 2021

On Deep Landscape Exploration of COVID-19 Patients Cells and Severity Markers

in Systems Immunology

Aarón Vázquez-Jiménez
Ugo Enrique Avila-Ponce De León
Meztli Matadamas-Guzman
Erick Andrés Muciño-Olmos
Yoscelina E. Martínez-López
Thelma Escobedo-Tapia
Osbaldo Resendis-Antonio

Frontiers in Immunology

doi 10.3389/fimmu.2021.705646

9,338 views
16 citations

Original Research

Published on 10 Sep 2021

Combined Transcriptome and Proteome Leukocyte’s Profiling Reveals Up-Regulated Module of Genes/Proteins Related to Low Density Neutrophils and Impaired Transcription and Translation Processes in Clinical Sepsis

in Systems Immunology

Giuseppe Gianini Figueirêdo Leite
Bianca Lima Ferreira
Alexandre Keiji Tashima
Erika Sayuri Nishiduka
Edecio Cunha-Neto
Milena Karina Colo Brunialti
Murillo Assuncao
Luciano Cesar Pontes Azevedo
Flávio Freitas
Tom van der Poll

Frontiers in Immunology

doi 10.3389/fimmu.2021.744799

11,419 views
26 citations

Perspective

Published on 07 Sep 2021

Literature Mining and Mechanistic Graphical Modelling to Improve mRNA Vaccine Platforms

in Systems Immunology

Lorena Leonardelli
Giuseppe Lofano
Gianluca Selvaggio
Silvia Parolo
Stefano Giampiccolo
Danilo Tomasoni
Enrico Domenici
Corrado Priami
Haifeng Song
Duccio Medini

Frontiers in Immunology

doi 10.3389/fimmu.2021.738388

5,916 views
6 citations

Original Research

Published on 07 Sep 2021

Simulating CXCR5 Dynamics in Complex Tissue Microenvironments

in Systems Immunology

Jason Cosgrove
Kieran Alden
Jens V. Stein
Mark C. Coles
Jon Timmis

Frontiers in Immunology

doi 10.3389/fimmu.2021.703088

4,257 views
1 citation

Original Research

Published on 31 Aug 2021

Characterization of the m6A-Associated Tumor Immune Microenvironment in Prostate Cancer to Aid Immunotherapy

in Systems Immunology

Zezhen Liu
Jiehui Zhong
Jie Zeng
Xiaolu Duan
Jianming Lu
Xinyuan Sun
Qinwei Liu
Yingke Liang
Zhuoyuan Lin
Weide Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2021.735170

11,231 views
60 citations

Original Research

Published on 19 Jul 2021

Antibody Repertoire Analysis of Tumor-Infiltrating B Cells Reveals Distinct Signatures and Distributions Across Tissues

in Systems Immunology

Ligal Aizik
Yael Dror
David Taussig
Adi Barzel
Yaron Carmi
Yariv Wine

Frontiers in Immunology

doi 10.3389/fimmu.2021.705381

12,536 views
20 citations

545 articles

articles

How to Prepare Spectral Flow Cytometry Datasets for High Dimensional Data Analysis: A Practical Workflow

Systems Biology to Understand and Regulate Human Retroviral Proinflammatory Response

FlowKit: A Python Toolkit for Integrated Manual and Automated Cytometry Analysis Workflows

Continuous Modeling of T CD4 Lymphocyte Activation and Function

Ductal Macrophages Predominate in the Immune Landscape of the Lactating Mammary Gland

FUCA2 Is a Prognostic Biomarker and Correlated With an Immunosuppressive Microenvironment in Pan-Cancer

N6-Methyladenosine Methylomic Landscape of Lung Tissues in Murine Acute Allergic Asthma

Mapping Pulmonary and Systemic Inflammation in Preschool Aged Children With Cystic Fibrosis

Immune Response in Severe and Non-Severe Coronavirus Disease 2019 (COVID-19) Infection: A Mechanistic Landscape

Determinants of Ligand Specificity and Functional Plasticity in Type I Interferon Signaling

System-Level Scenarios for the Elucidation of T Cell-Mediated Germinal Center B Cell Differentiation

On Deep Landscape Exploration of COVID-19 Patients Cells and Severity Markers

Combined Transcriptome and Proteome Leukocyte’s Profiling Reveals Up-Regulated Module of Genes/Proteins Related to Low Density Neutrophils and Impaired Transcription and Translation Processes in Clinical Sepsis

Literature Mining and Mechanistic Graphical Modelling to Improve mRNA Vaccine Platforms

Simulating CXCR5 Dynamics in Complex Tissue Microenvironments

Characterization of the m6A-Associated Tumor Immune Microenvironment in Prostate Cancer to Aid Immunotherapy

Antibody Repertoire Analysis of Tumor-Infiltrating B Cells Reveals Distinct Signatures and Distributions Across Tissues