Frontiers in Immunology | Systems Immunology

Original Research

Published on 04 Feb 2025

Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers

in Systems Immunology

Ruohua Li
Cuixia Zhou
Kejun Ye
Haihui Chen
Mengjia Peng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1496046

1,311 views
1 citation

Original Research

Published on 23 Jan 2025

Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning

in Systems Immunology

Tao Zhou
Can Zhu
Wei Zhang
Qiongfang Wu
Mingqiang Deng
Zhiwei Jiang
Longfei Peng
Hao Geng
Zhouting Tuo
Ci Zou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1511529

1,593 views

Original Research

Published on 23 Jan 2025

Feature selection enhances peptide binding predictions for TCR-specific interactions

in Systems Immunology

Hamid Teimouri
Zahra S. Ghoreyshi
Anatoly B. Kolomeisky
Jason T. George

Frontiers in Immunology

doi 10.3389/fimmu.2024.1510435

1,381 views

Original Research

Published on 23 Jan 2025

Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia

in Systems Immunology

Rong Lin
XiaoYing Weng
Liang Lin
XuYang Hu
ZhiYan Liu
Jing Zheng
FenFang Shen
Rui Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1453633

1,193 views
1 citation

Original Research

Published on 20 Jan 2025

Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion in astronauts’ blood cells in space

in Systems Immunology

Maria Moreno-Villanueva
Luis E. Jimenez-Chavez
Stephanie Krieger
Liang-Hao Ding
Ye Zhang
Adriana Babiak-Vazquez
Mark Berres
Sandra Splinter
Kristen E. Pauken
Brian C. Schaefer

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512578

2,386 views

Original Research

Published on 20 Jan 2025

Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1–infected women is associated with lower viral loads

in Systems Immunology

Elina El-Badry
Luxiao Chen
Khader Ghneim
Ziyi Li
Kelsie Brooks
Jake Rhodes
Rafick Sekaly
William Kilembe
Susan Allen
Hao Wu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1507530

1,328 views

Original Research

Published on 14 Jan 2025

Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anti-citrullinated peptide antibody-positive early rheumatoid arthritis

in Systems Immunology

Bong-Ki Hong
Sungyong You
Jung Gon Kim
Minhyung Kim
Naeun Lee
Kijun Lee
In-Pyo Baek
Ji Hyeon Ju
Wan-Uk Kim
Ho-Youn Kim

Frontiers in Immunology

doi 10.3389/fimmu.2024.1439082

1,508 views

Original Research

Published on 14 Jan 2025

Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets

in Systems Immunology

Huahua Li
Lingling Zou
Zhaowei Long
Junkun Zhan

Frontiers in Immunology

doi 10.3389/fimmu.2024.1537909

1,866 views
1 citation

Original Research

Published on 14 Jan 2025

Network pharmacology and multi-omics validation of the Jianpi-Yishen formula in the treatment of chronic kidney disease

in Systems Immunology

Yuyan Li
Yueming Luo
Yilan Hu
Siting Li
Guandong Li
Wanyangchuan Zhang
Xiufen Gu
Jianting Wang
Shunmin Li
Hong Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512519

1,539 views

Original Research

Published on 13 Jan 2025

Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective

in Systems Immunology

Didar Murad
Rehan Zafar Paracha
Maryum Nisar

Frontiers in Immunology

doi 10.3389/fimmu.2024.1457324

1,648 views

Original Research

Published on 13 Jan 2025

Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks

in Systems Immunology

Dakota N. Paine
Meghan Hermance
Saravanan Thangamani

Frontiers in Immunology

doi 10.3389/fimmu.2024.1511132

1,114 views

Original Research

Published on 13 Jan 2025

Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases

in Systems Immunology

Cheng-Cheng Deng
Xue-Yan Xu
Yan Zhang
Long-Can Liu
Xuan Wang
Jun-Yi Chen
Liu-Yi Yao
Ding-Heng Zhu
Bin Yang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1522076

2,562 views

Mini Review

Published on 10 Jan 2025

Tuberculous meningitis diagnosis and treatment: classic approaches and high-throughput pathways

in Systems Immunology

Fangbo Lin

Frontiers in Immunology

doi 10.3389/fimmu.2024.1543009

2,603 views
1 citation

Review

Published on 09 Jan 2025

Advancing precision cancer immunotherapy drug development, administration, and response prediction with AI-enabled Raman spectroscopy

in Systems Immunology

Jay Chadokiya
Kai Chang
Saurabh Sharma
Jack Hu
Jennie R. Lill
Jennifer Dionne
Amanda Kirane

Frontiers in Immunology

doi 10.3389/fimmu.2024.1520860

2,481 views
1 citation

Original Research

Published on 08 Jan 2025

Drp1–associated genes implicated in sepsis survival

in Systems Immunology

Marissa D. Pokharel
Anlin Feng
Ying Liang
Wenli Ma
Saurabh Aggarwal
Hoshang Unwalla
Stephen M. Black
Ting Wang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1516145

1,105 views

Original Research

Published on 06 Jan 2025

Single-cell mitophagy patterns within the tumor microenvironment modulate intercellular communication, impacting the progression and prognosis of hepatocellular carcinoma

in Systems Immunology

Zhengyan Li
Wei Chen
Shu Yao
Zuxiang Peng
Hongming Liu
Yongliang Tang
Yi Feng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1448878

1,630 views