Frontiers in Immunology | Systems Immunology

Original Research

Published on 14 Jan 2025

Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets

in Systems Immunology

Huahua Li
Lingling Zou
Zhaowei Long
Junkun Zhan

Frontiers in Immunology

doi 10.3389/fimmu.2024.1537909

3,443 views
3 citations

Original Research

Published on 14 Jan 2025

Network pharmacology and multi-omics validation of the Jianpi-Yishen formula in the treatment of chronic kidney disease

in Systems Immunology

Yuyan Li
Yueming Luo
Yilan Hu
Siting Li
Guandong Li
Wanyangchuan Zhang
Xiufen Gu
Jianting Wang
Shunmin Li
Hong Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512519

2,813 views

Original Research

Published on 13 Jan 2025

Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks

in Systems Immunology

Dakota N. Paine
Meghan Hermance
Saravanan Thangamani

Frontiers in Immunology

doi 10.3389/fimmu.2024.1511132

1,624 views
1 citation

Original Research

Published on 13 Jan 2025

Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective

in Systems Immunology

Didar Murad
Rehan Zafar Paracha
Maryum Nisar

Frontiers in Immunology

doi 10.3389/fimmu.2024.1457324

2,326 views

Original Research

Published on 13 Jan 2025

Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases

in Systems Immunology

Cheng-Cheng Deng
Xue-Yan Xu
Yan Zhang
Long-Can Liu
Xuan Wang
Jun-Yi Chen
Liu-Yi Yao
Ding-Heng Zhu
Bin Yang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1522076

4,732 views
3 citations

Mini Review

Published on 10 Jan 2025

Tuberculous meningitis diagnosis and treatment: classic approaches and high-throughput pathways

in Systems Immunology

Fangbo Lin

Frontiers in Immunology

doi 10.3389/fimmu.2024.1543009

5,914 views
2 citations

Review

Published on 09 Jan 2025

Advancing precision cancer immunotherapy drug development, administration, and response prediction with AI-enabled Raman spectroscopy

in Systems Immunology

Jay Chadokiya
Kai Chang
Saurabh Sharma
Jack Hu
Jennie R. Lill
Jennifer Dionne
Amanda Kirane

Frontiers in Immunology

doi 10.3389/fimmu.2024.1520860

3,908 views
1 citation

Original Research

Published on 08 Jan 2025

Drp1–associated genes implicated in sepsis survival

in Systems Immunology

Marissa D. Pokharel
Anlin Feng
Ying Liang
Wenli Ma
Saurabh Aggarwal
Hoshang Unwalla
Stephen M. Black
Ting Wang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1516145

1,577 views

Original Research

Published on 06 Jan 2025

Single-cell mitophagy patterns within the tumor microenvironment modulate intercellular communication, impacting the progression and prognosis of hepatocellular carcinoma

in Systems Immunology

Zhengyan Li
Wei Chen
Shu Yao
Zuxiang Peng
Hongming Liu
Yongliang Tang
Yi Feng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1448878

2,826 views

Original Research

Published on 03 Jan 2025

Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencing

in Systems Immunology

Yafeng Jiang
Zhaolan Hu
Roujie Huang
Kaying Ho
Pengfei Wang
Jin Kang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512483

3,316 views
1 citation

Original Research

Published on 23 Dec 2024

Geny: a genotyping tool for allelic decomposition of killer cell immunoglobulin-like receptor genes

in Systems Immunology

Qinghui Zhou
Mazyar Ghezelji
Ananth Hari
Michael K. B. Ford
Connor Holley
S. Cenk Sahinalp
Ibrahim Numanagić

Frontiers in Immunology

doi 10.3389/fimmu.2024.1494995

934 views

Original Research

Published on 11 Dec 2024

Nervonic acid alleviates radiation-induced early phase lung inflammation by targeting macrophages activation in mice

in Systems Immunology

Chenlin Wang
Yanan Wu
Chao Liu
Yang Li
Song Mi
Xiaofan Yang
Tong Liu
Yuanjing Tian
YingYing Zhang
Pingping Hu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1405020

1,715 views
2 citations

Editorial

Published on 09 Dec 2024

Editorial: Systems immunology to advance vaccine development

in Systems Immunology

Jue Hou
Helder I. Nakaya

Frontiers in Immunology

doi 10.3389/fimmu.2024.1527238

1,121 views

Original Research

Published on 06 Dec 2024

Effects of PGK1 on immunoinfiltration by integrated single-cell and bulk RNA-sequencing analysis in sepsis

in Systems Immunology

Yu Liu
Weijie Li
Lei Lei
Yaoliang Zhou
Mingcheng Huang
Yide Li
Xiaoying Zhang
Yingyu Jiang
Haiqi Wu
Zhihua Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1449975

2,870 views
1 citation

Original Research

Published on 06 Dec 2024

Remodeling of the chromatin landscape in peripheral blood cells in patients with severe Delta COVID-19

in Systems Immunology

Vasiliy E. Akimov
Dmitriy I. Tychinin
Olga A. Antonova
Abusaid M. Shaymardanov
Maria D. Voronina
Kseniia A. Deinichenko
Oleg D. Fateev
Vladimir S. Yudin
Sergey M. Yudin
Vladimir E. Mukhin

Frontiers in Immunology

doi 10.3389/fimmu.2024.1415317

1,957 views

Original Research

Published on 05 Dec 2024

Evaluating methods for integrating single-cell data and genetics to understand inflammatory disease complexity

in Systems Immunology

Hope A. Townsend
Kaylee J. Rosenberger
Lauren A. Vanderlinden
Jun Inamo
Fan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1454263

4,709 views
1 citation