Frontiers in Immunology | Systems Immunology

Original Research

Published on 13 Jan 2025

Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks

in Systems Immunology

Dakota N. Paine
Meghan Hermance
Saravanan Thangamani

Frontiers in Immunology

doi 10.3389/fimmu.2024.1511132

2,804 views
4 citations

Original Research

Published on 13 Jan 2025

Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective

in Systems Immunology

Didar Murad
Rehan Zafar Paracha
Maryum Nisar

Frontiers in Immunology

doi 10.3389/fimmu.2024.1457324

4,484 views
3 citations

Original Research

Published on 13 Jan 2025

Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases

in Systems Immunology

Cheng-Cheng Deng
Xue-Yan Xu
Yan Zhang
Long-Can Liu
Xuan Wang
Jun-Yi Chen
Liu-Yi Yao
Ding-Heng Zhu
Bin Yang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1522076

9,983 views
9 citations

Mini Review

Published on 10 Jan 2025

Tuberculous meningitis diagnosis and treatment: classic approaches and high-throughput pathways

in Systems Immunology

Fangbo Lin

Frontiers in Immunology

doi 10.3389/fimmu.2024.1543009

16,312 views
5 citations

Review

Published on 09 Jan 2025

Advancing precision cancer immunotherapy drug development, administration, and response prediction with AI-enabled Raman spectroscopy

in Systems Immunology

Jay Chadokiya
Kai Chang
Saurabh Sharma
Jack Hu
Jennie R. Lill
Jennifer Dionne
Amanda Kirane

Frontiers in Immunology

doi 10.3389/fimmu.2024.1520860

7,173 views
6 citations

Original Research

Published on 08 Jan 2025

Drp1–associated genes implicated in sepsis survival

in Systems Immunology

Marissa D. Pokharel
Anlin Feng
Ying Liang
Wenli Ma
Saurabh Aggarwal
Hoshang Unwalla
Stephen M. Black
Ting Wang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1516145

2,676 views
1 citation

Original Research

Published on 06 Jan 2025

Single-cell mitophagy patterns within the tumor microenvironment modulate intercellular communication, impacting the progression and prognosis of hepatocellular carcinoma

in Systems Immunology

Zhengyan Li
Wei Chen
Shu Yao
Zuxiang Peng
Hongming Liu
Yongliang Tang
Yi Feng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1448878

4,876 views
1 citation

Original Research

Published on 03 Jan 2025

Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencing

in Systems Immunology

Yafeng Jiang
Zhaolan Hu
Roujie Huang
Kaying Ho
Pengfei Wang
Jin Kang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512483

6,175 views
5 citations

Original Research

Published on 23 Dec 2024

Geny: a genotyping tool for allelic decomposition of killer cell immunoglobulin-like receptor genes

in Systems Immunology

Qinghui Zhou
Mazyar Ghezelji
Ananth Hari
Michael K. B. Ford
Connor Holley
S. Cenk Sahinalp
Ibrahim Numanagić

Frontiers in Immunology

doi 10.3389/fimmu.2024.1494995

1,768 views
1 citation

Original Research

Published on 11 Dec 2024

Nervonic acid alleviates radiation-induced early phase lung inflammation by targeting macrophages activation in mice

in Systems Immunology

Chenlin Wang
Yanan Wu
Chao Liu
Yang Li
Song Mi
Xiaofan Yang
Tong Liu
Yuanjing Tian
YingYing Zhang
Pingping Hu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1405020

3,182 views
3 citations

Editorial

Published on 09 Dec 2024

Editorial: Systems immunology to advance vaccine development

in Systems Immunology

Jue Hou
Helder I. Nakaya

Frontiers in Immunology

doi 10.3389/fimmu.2024.1527238

2,789 views

Original Research

Published on 06 Dec 2024

Effects of PGK1 on immunoinfiltration by integrated single-cell and bulk RNA-sequencing analysis in sepsis

in Systems Immunology

Yu Liu
Weijie Li
Lei Lei
Yaoliang Zhou
Mingcheng Huang
Yide Li
Xiaoying Zhang
Yingyu Jiang
Haiqi Wu
Zhihua Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1449975

5,473 views
2 citations

Original Research

Published on 06 Dec 2024

Remodeling of the chromatin landscape in peripheral blood cells in patients with severe Delta COVID-19

in Systems Immunology

Vasiliy E. Akimov
Dmitriy I. Tychinin
Olga A. Antonova
Abusaid M. Shaymardanov
Maria D. Voronina
Kseniia A. Deinichenko
Oleg D. Fateev
Vladimir S. Yudin
Sergey M. Yudin
Vladimir E. Mukhin

Frontiers in Immunology

doi 10.3389/fimmu.2024.1415317

3,155 views
2 citations

Original Research

Published on 05 Dec 2024

Comprehensive analysis of skin growth-related hub genes and microenvironment characterization in a mouse expanded skin model

in Systems Immunology

Yinmin Wang
Wenxiao Qi
Shun Yu
Xianyu Zhou
Xiuxia Wang
Fei Liu
Rui Jin
Xusong Luo
Qiangliang Ma
Lin Lu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1306353

3,005 views
1 citation

Original Research

Published on 05 Dec 2024

Evaluating methods for integrating single-cell data and genetics to understand inflammatory disease complexity

in Systems Immunology

Hope A. Townsend
Kaylee J. Rosenberger
Lauren A. Vanderlinden
Jun Inamo
Fan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1454263

7,817 views
3 citations

Original Research

Published on 04 Dec 2024

Machine learning-based diagnostic model of lymphatics-associated genes for new therapeutic target analysis in intervertebral disc degeneration

in Systems Immunology

Maoqiang Lin
Shaolong Li
Yabin Wang
Guan Zheng
Fukang Hu
Qiang Zhang
Pengjie Song
Haiyu Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2024.1441028

4,157 views
2 citations

Original Research

Published on 27 Nov 2024

Computational analysis of the functional impact of MHC-II-expressing triple-negative breast cancer

in Systems Immunology

Yang Cui
Weihang Zhang
Xin Zeng
Yitao Yang
Sung-Joon Park
Kenta Nakai

Frontiers in Immunology

doi 10.3389/fimmu.2024.1497251

5,014 views
5 citations

Original Research

Published on 22 Nov 2024

Identification of early Alzheimer’s disease subclass and signature genes based on PANoptosis genes

in Systems Immunology

Wenxu Wang
Jincheng Lu
Ningyun Pan
Huiying Zhang
Jingcen Dai
Jie Li
Cheng Chi
Liumei Zhang
Liang Wang
Mengying Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1462003

8,400 views
8 citations

Review

Published on 12 Nov 2024

Navigating the nano-bio immune interface: advancements and challenges in CNS nanotherapeutics

in Systems Immunology

Chantalle Moulton
Anna Baroni
Erica Quagliarini
Lucia Leone
Luca Digiacomo
Marta Morotti
Giulio Caracciolo
Maria Vittoria Podda
Ennio Tasciotti

Frontiers in Immunology

doi 10.3389/fimmu.2024.1447567

3,998 views
4 citations

Brief Research Report

Published on 11 Nov 2024

Periodontal ligament tissues support neutrophil differentiation and maturation processes

in Systems Immunology

Guillermo Villagómez-Olea
Eileen Uribe-Querol
Francisco Javier Marichi-Rodríguez
Jorge Meléndez-Zajgla
Marco Antonio Alvaréz-Pérez
Carlos Rosales

Frontiers in Immunology

doi 10.3389/fimmu.2024.1446541

3,851 views
1 citation

Original Research

Published on 11 Nov 2024

Molecular hybridization modification improves the stability and immunomodulatory activity of TP5 peptide

in Systems Immunology

Junyong Wang
Yuan Tang
Xuelian Zhao
Zetao Ding
Marhaba Ahmat
Dayong Si
Rijun Zhang
Xubiao Wei

Frontiers in Immunology

doi 10.3389/fimmu.2024.1472839

2,261 views
4 citations

Original Research

Published on 07 Nov 2024

Ensemble modeling of SARS-CoV-2 immune dynamics in immunologically naïve rhesus macaques predicts that potent, early innate immune responses drive viral elimination

in Systems Immunology

Catherine Byrne
Joshua T. Schiffer

Frontiers in Immunology

doi 10.3389/fimmu.2024.1426016

2,233 views
4 citations

Review

Published on 04 Nov 2024

Gut microbiome and metabolomics in systemic sclerosis: feature, link and mechanisms

in Systems Immunology

Qicen Yao
Wenfeng Tan
Feihu Bai

Frontiers in Immunology

doi 10.3389/fimmu.2024.1475528

5,430 views
8 citations

Original Research

Published on 30 Oct 2024

A cost-effective protocol for single-cell RNA sequencing of human skin

in Systems Immunology

Saba Khoshbakht
Özgür Albayrak
Ergün Tiryaki
Orhan Ağcaoğlu
Ayşe Öktem
Gizem Pınar Sun
Elif Er Gülbezer
Sümeyre Seda Ertekin
Ayşe Boyvat
Atay Vural

Frontiers in Immunology

doi 10.3389/fimmu.2024.1393017

3,835 views
4 citations

523 articles

articles

Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks

Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective

Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases

Tuberculous meningitis diagnosis and treatment: classic approaches and high-throughput pathways

Advancing precision cancer immunotherapy drug development, administration, and response prediction with AI-enabled Raman spectroscopy

Drp1–associated genes implicated in sepsis survival

Single-cell mitophagy patterns within the tumor microenvironment modulate intercellular communication, impacting the progression and prognosis of hepatocellular carcinoma

Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencing

Geny: a genotyping tool for allelic decomposition of killer cell immunoglobulin-like receptor genes

Nervonic acid alleviates radiation-induced early phase lung inflammation by targeting macrophages activation in mice

Editorial: Systems immunology to advance vaccine development

Effects of PGK1 on immunoinfiltration by integrated single-cell and bulk RNA-sequencing analysis in sepsis

Remodeling of the chromatin landscape in peripheral blood cells in patients with severe Delta COVID-19

Comprehensive analysis of skin growth-related hub genes and microenvironment characterization in a mouse expanded skin model

Evaluating methods for integrating single-cell data and genetics to understand inflammatory disease complexity

Machine learning-based diagnostic model of lymphatics-associated genes for new therapeutic target analysis in intervertebral disc degeneration

Computational analysis of the functional impact of MHC-II-expressing triple-negative breast cancer

Identification of early Alzheimer’s disease subclass and signature genes based on PANoptosis genes

Navigating the nano-bio immune interface: advancements and challenges in CNS nanotherapeutics

Periodontal ligament tissues support neutrophil differentiation and maturation processes

Molecular hybridization modification improves the stability and immunomodulatory activity of TP5 peptide

Ensemble modeling of SARS-CoV-2 immune dynamics in immunologically naïve rhesus macaques predicts that potent, early innate immune responses drive viral elimination

Gut microbiome and metabolomics in systemic sclerosis: feature, link and mechanisms

A cost-effective protocol for single-cell RNA sequencing of human skin