Frontiers in Immunology | T Cell Biology

Brief Research Report

Published on 20 Aug 2025

Assessing the impact of TET2 and TET3 deletion in TCRalpha and TCRbeta repertoire in murine CD4 T cells in physiological and pathophysiological conditions

in T Cell Biology

Tarmo Äijö
Marianthi Gioulbasani
Jair Ernesto Valenzuela
Ageliki Tsagaratou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638500

133 views

Review

Accepted on 15 Aug 2025

The Emerging Role of Tissue Regulatory T Cells in Tissue Repair and Regeneration

in T Cell Biology

Abdul Raheem
Ilyas Khan
Iqbal Ahmad
Abdul Wajid
Mohammad Y Alshahrani
Fuad M Alzahrani
Khalid Alzahrani
Abdul Qadeer
I-Chuang Liao
Chien-Chin Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640113

157 views

Review

Published on 15 Aug 2025

Epigenetic control of tissue resident memory T cells

in T Cell Biology

Zhiyi Lan
Zeyu Chen
Nan Yang
Tong Liu
Siqi Li
Yuling Shi
Jun Gu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605972

508 views

Mini Review

Published on 14 Aug 2025

Immunobiology roles of the human CD161 receptor in T cells

in T Cell Biology

Bainan Tong
Mingxuan Wang
Lu Liu
Xinyue Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648305

365 views

Original Research

Published on 14 Aug 2025

Retinoic acid receptor-related orphan receptor α regulates bystander activation of memory CD8+ T cells

in T Cell Biology

Zimeng Cai
Mina Kozai
Hironobu Mita
Hiroto Takeuchi
Satoru Mizuno
Kazuhiro Matsuo
Kensuke Takada

Frontiers in Immunology

doi 10.3389/fimmu.2025.1647746

499 views

Original Research

Accepted on 13 Aug 2025

Unveiling altered CD8 T-cell metabolism and homeostatic proliferation behind a low CD4/CD8 ratio in ART-suppressed HIV individuals with normal CD4 recovery

in T Cell Biology

Vanesa Garrido-Rodríguez
Angel Bulnes-Ramos
Israel Olivas-Martínez
María Del Mar Pozo-Balado
Francisco Tejerina-Picado
Félix Gutiérrez
Cristina Marco-Sánchez
Juan Tiraboschi
Antonia Castillo-Navarro
Enrique Bernal Morell

Frontiers in Immunology

doi 10.3389/fimmu.2025.1617674

Original Research

Published on 12 Aug 2025

Susceptibility to and severity of tuberculosis infection in mice depends upon MHC-II-determined level of activation-inhibition balance in CD4 T-cells

in T Cell Biology

Nadezhda Logunova
Marina Kapina
Valeriia Kriukova
Olga Britanova
Konstantin Majorov
Irina Linge
Alexander Apt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608769

428 views

Case Report

Accepted on 11 Aug 2025

Mesenchymal stromal cells as rescue therapy in biologic-refractory psoriasis: insights from a case series

in T Cell Biology

Su Mar Lwin
Shane Solanky
Cristiano Scottà
Chiara Giacomini
Shir Azrielant
Isabella Tosi
Atheer Al-Haddabi
Emelia Duarte-Williamson
Hannah Dawe
Sarah Walsh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656724

174 views

Original Research

Accepted on 11 Aug 2025

Targeting IL-6 receptor mediated metabolic pathways to control Th17 cell differentiation and inflammatory responses

in T Cell Biology

Yazan Alwarawrah
Amanda G Nichols
Isha Patel
Andrea B Ball
Nancie J MacIver

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568514

Original Research

Published on 11 Aug 2025

CD39 dynamics in tuberculosis: a potential biomarker of immune dysregulation and T cell exhaustion

in T Cell Biology

Ling Hao
Qari Muhammad Imran
Nadeem Ullah

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601637

720 views

Review

Accepted on 08 Aug 2025

Innate iNKT cells: from biological insight to clinical impact

in T Cell Biology

Antonia Rotolo
Nicola Mason
Mark A. Exley

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653183

167 views

Review

Published on 07 Aug 2025

Autoimmune disease: genetic susceptibility, environmental triggers, and immune dysregulation. Where can we develop therapies?

in T Cell Biology

Manoj Kumar
Linda Yip
Fangyuan Wang
Saci-Elodie Marty
C. Garrison Fathman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626082

917 views

Original Research

Published on 06 Aug 2025

Loss of Cullin 5 in myeloid cells protects against autoimmune neuroinflammation

in T Cell Biology

Yohaniz Ortega-Burgos
Asif A. Dar
Siera A. Tomishima
Ipsita Guha
Carleigh O’ Brien
Nadia Porter
F. Chris Bennett
Paula M. Oliver

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611818

660 views

Original Research

Accepted on 04 Aug 2025

Increased frequencies of human Th-17 CD4+ T-cells and decreased Tregulatory cells in patients with early and advanced metabolic dysfunction-associated steatotic liver disease (MASLD)

in T Cell Biology

Elżbieta Supruniuk
Kamil Grubczak
Anna Parfieniuk-Kowerda
Robert Flisiak
Marcin Moniuszko
Jerzy Jaroszewicz
Adrian Chabowski
Magdalena Świderska

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597204

157 views

Mini Review

Accepted on 04 Aug 2025

Gzmk + CD8 T cells in inflammatory diseases

in T Cell Biology

Wenqiang Cao
Cui Xin
peiyun liu
qianqian zhan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661755

131 views

Mini Review

Published on 01 Aug 2025

Fine-tuning immunity: ubiquitin-dependent regulation of interleukin-17A expression by Th17 cells

in T Cell Biology

Desh Raj
Amit K. Verma
Risha Mathur
Jenna Woody
Mahesh Kathania
K. Venuprasad

Frontiers in Immunology

doi 10.3389/fimmu.2025.1614409

743 views