Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Published on 01 Jul 2025

The F1F3 recombinant chimera induced higher vaccine efficacy than its independent F1 and F3 components against Leishmania (L.) infantum chagasi mice infection

in Vaccines and Molecular Therapeutics

Daniele Crespo Gomes
Maria Paula Fonseca-Ribeiro
Marcus Vinicius Alves-Silva
Clarisa B. Palatnik-de-Sousa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598755

177 views

Original Research

Published on 01 Jul 2025

Quantitative bead–based multiplex assay for simultaneous determination of IgG concentrations of pertussis toxin, filamentous hemagglutinin, pertactin, diphtheria, tetanus, Haemophilus influenzae b, and hepatitis B in human serum samples

in Vaccines and Molecular Therapeutics

Vishal Rathod
Sagar Katke
Sumant Patil
Sachin Bhandare
Laxmikant Kadam
Manish Gautam
Prabhu Gumma
Krishna Manoj Kumar
Laura Hassall
Cathy Asokanathan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587567

229 views

Original Research

Published on 30 Jun 2025

Influenza-specific antibody-mediated and complement-dependent cellular cytotoxicity-inducing antibodies in vaccinated and infected pigs

in Vaccines and Molecular Therapeutics

Mithilesh Singh
Gabriela Mansano do Nascimento
Sankar Renu
Dina Bugybayeva
Olaitan C. Shekoni
Raksha Suresh
Jennifer Schrock
Sara Dolatyabi
Diego G. Diel
Prosper N. Boyaka

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600761

589 views

Correction

Published on 30 Jun 2025

Correction: Development of a subunit vaccine against the cholangiocarcinoma causing Opisthorchis viverrini: a computational approach

in Vaccines and Molecular Therapeutics

Mohibullah Shah
Farva Sitara
Asifa Sarfraz
Muhammad Shehroz
Tehreem Ul Wara
Asia Perveen
Najeeb Ullah
Aqal Zaman
Umar Nishan
Sarfraz Ahmed

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638914

135 views

Original Research

Accepted on 28 Jun 2025

Immune Memory Reactivation and T Cell Dynamics Following 12-Month Homologous CoronaVac Booster: A Longitudinal Cohort Study

in Vaccines and Molecular Therapeutics

Xinran Song
Weixin Chen
Shuang Bai
Min Lv
Jian Wang
Ao Zhang
Jiang Wu
Wei Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636629

413 views

Original Research

Accepted on 28 Jun 2025

Study of dense granule proteins in Eimeria spp. identifies a limited repertoire with potential as vaccine candidates

in Vaccines and Molecular Therapeutics

Gonzalo Sánchez-Arsuaga
Damer Blake
Fiona Tomley
Virginia Marugan-Hernandez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605984

316 views

Original Research

Accepted on 27 Jun 2025

Mixed lipopeptide-based mucosal vaccine elicits a long-term bone marrow memory response that is potentially cross-reactive against a broad-spectrum of coronaviruses in mice

in Vaccines and Molecular Therapeutics

Raj Samir Patel
Babita Agrawal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1619882

262 views

Brief Research Report

Published on 27 Jun 2025

Pre-clinical allergenicity assessment of IgE epitope-targeted Der p 2 mutants demonstrate potential as hypoallergenic AIT candidates

in Vaccines and Molecular Therapeutics

Glorismer Pena-Amelunxen
Mohadeseh Asghari
Kriti Khatri
Jill Glesner
Serge A. Versteeg
Ronald van Ree
Martin D. Chapman
Scott A. Smith
Maksymilian Chruszcz
Anna Pomés

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623920

337 views

Original Research

Accepted on 26 Jun 2025

Comparison of SARS-CoV-2 Immune Responses Following Vaccination with Comirnaty (Pfizer) and Vaxzevria (AstraZeneca) in Healthy Individuals with or without Prior SARS-CoV-2 Infection

in Vaccines and Molecular Therapeutics

Zdzisława Kondera- Anasz
Emilia Justyna Morawiec
Roksana Duszkiewicz
Filip Hajdrowski
Andrzej Wiczkowski

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612288

244 views

Original Research

Accepted on 26 Jun 2025

MetE: A Promising Protective Antigen for Tuberculosis Vaccine Development

in Vaccines and Molecular Therapeutics

Salem Salman Almujri
Elena Stylianou
Annalisa Nicastri
Iman Satti
Marcellus Korompis
Shuailin Li
Christopher De Voss
Marco Polo Peralta Alvarez
Rachel Tanner
Paulo J.G. Bettencourt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593263

133 views

Brief Research Report

Published on 26 Jun 2025

Sexual dimorphism-driven differences are overcome in a preclinical vaccine model against Trypanosoma cruzi

in Vaccines and Molecular Therapeutics

Camila Bulfoni Balbi
Maria Florencia Pacini
Brenda Dinatale
Cecilia Farré
Paula Cacik
Estefanía Prochetto
Florencia Belén González
Iván Marcipar
Gabriel Cabrera
Ana Rosa Pérez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526573

406 views

Original Research

Published on 26 Jun 2025

A consensus mathematical model of vaccine-induced antibody dynamics for multiple vaccine platforms and pathogens

in Vaccines and Molecular Therapeutics

Kristen M. Wilding
Carmen Molina-París
Jessica Z. Kubicek-Sutherland
Benjamin McMahon
Alan S. Perelson
Ruy M. Ribeiro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596518

391 views

Original Research

Published on 26 Jun 2025

Nanolipoprotein particle (NLP) vaccine confers protection against Yersinia pestis aerosol challenge in a BALB/c mouse model

in Vaccines and Molecular Therapeutics

Sergei S. Biryukov
Amy Rasley
Michael L. Davies
Christopher P. Klimko
Jennifer L. Dankmeyer
Melissa Hunter
Nathaniel O. Rill
Jennifer L. Shoe
Jeremy Miller
Yuli Talyansky

Frontiers in Immunology

doi 10.3389/fimmu.2025.1603710

745 views

Original Research

Accepted on 25 Jun 2025

Non-Cognate Ligands of Hepatitis C Virus Envelope Broadly Neutralizing Antibodies Induce Virus-neutralizing Sera in Mice

in Vaccines and Molecular Therapeutics

Stephen Ian Walimbwa
Shiv Bharadwaj
Petr Kosztyu
Lucie Vankova
Milan Kuchar
Eliska Kopecna
Roman Effenberg
Lukas Drasar
Leona Raskova Kafkova
Petr Maly

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624299

Brief Research Report

Published on 25 Jun 2025

Immune responses following DNA vaccination by needle-free injection against Burkholderia pseudomallei hemolysin co-regulated protein 1

in Vaccines and Molecular Therapeutics

Michael L. Davies
Sergei S. Biryukov
Christopher P. Klimko
Jennifer L. Dankmeyer
Nathaniel O. Rill
Melissa Hunter
Christopher T. Braun
Deven W. Patrick
Tyrique D. David
Steven A. Kwilas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612540

380 views

Review

Published on 25 Jun 2025

Progress in combination vaccines and the co-administration of influenza virus and SARS-CoV-2 vaccines

in Vaccines and Molecular Therapeutics

Chengyu Hu
Chenguang Niu
Xiaohui Li
Ke He
Mengyu Li
Xiaonan Gao
Qiannan Wei
Weiyang Sun
Yongkun Zhao
Yuanguo Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578733

771 views