Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Published on 04 Aug 2025

Neutralizing antibody response to different COVID-19 vaccines in Brazil: the impact of previous infection and booster doses

in Vaccines and Molecular Therapeutics

Beatriz L. L. Caetano
Paolla B. A. Pinto
Agatha R. Pacheco
Agnes R. Lage
Aline S. G. Pereira
Amanda V. P. Nascimento
Thiago R. Machado
Anderson Paulino
Thiago L. Medeiros
Lorena O. Fernandes-Siqueira

Frontiers in Immunology

doi 10.3389/fimmu.2025.1603612

3,147 views

Original Research

Published on 01 Aug 2025

Evaluation of the viability and functionality of human peripheral blood mononuclear cells cryopreserved up to 2 years in animal-protein-free freezing media compared to the FBS-supplemented reference medium

in Vaccines and Molecular Therapeutics

Frédérique Jantet-Blaudez
Joseline Ruiz
Sylviane Gautheron
Anke Pagnon

Frontiers in Immunology

doi 10.3389/fimmu.2025.1627973

4,329 views
2 citations

Original Research

Published on 01 Aug 2025

Autovaccine immunoprophylaxis in patients with neurogenic bladder experiencing recurrent urinary tract infections

in Vaccines and Molecular Therapeutics

Miguel Ángel Bonillo-García
Domingo Guzmán Ordaz-Jurado
Juan Ortiz-Salvador
Josep Oriol Colet-Guitert
Eduardo Morán-Pascual
Esther Martínez-Cuenca
Salvador Arlandis-Guzmán

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626422

2,152 views
1 citation

Original Research

Published on 01 Aug 2025

The immunogenicity and safety of an inactivated quadrivalent influenza vaccine and a 23-valent pneumococcal polysaccharide vaccine in individuals with chronic diseases

in Vaccines and Molecular Therapeutics

Wanqin Tang
Xi Lu
Zhongkui Zhu
Dan Yu
Huaxian Liu
Yufei Song
Lu Shen
Yang Yu
Yanwei Zhao
Yan Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624095

3,230 views

Original Research

Published on 31 Jul 2025

Dose-sparing effects of novel adjuvants and aluminum hydroxide on two different vaccines in a neonatal mouse model

in Vaccines and Molecular Therapeutics

Jenny Lorena Molina Estupiñan
Poorya Foroutan Pajoohian
Gabriel Kristian Pedersen
Dennis Christensen
Serena Marchi
Emanuele Montomoli
Stefanía P. Bjarnarson
Ingileif Jonsdottir
Audur Anna Aradottir Pind

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646677

3,688 views

Original Research

Published on 31 Jul 2025

Fc-modification of anti-PcrV gene-encoded antibodies modulates complement-mediated killing of Pseudomonas aeruginosa

in Vaccines and Molecular Therapeutics

Jillian Eisenhauer
Spencer Dublin
Jihae Choi
Abigail R. Trachtman
Jacqueline D. Chu
David Custodio-Zegarra
Suman Bharti
Bhavya Bhardwaj
Shuangyi Bai
William T. Witt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618297

3,987 views

Original Research

Published on 31 Jul 2025

MDSC depletion during immunization with heat-killed Mycobacterium tuberculosis increases protection against BCG infection

in Vaccines and Molecular Therapeutics

Arpa Aintablian
Anna M. Arold
Haisam Alattar
Laura Cyran
Christoph Schoen
Nelita Du Plessis
Gerhard Walzl
Ulrich Schaible
Andreas Beilhack
Natalie E. Nieuwenhuizen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646526

3,552 views
1 citation

Review

Published on 30 Jul 2025

BCG and beyond: unlocking new frontiers in TB vaccine development

in Vaccines and Molecular Therapeutics

Aishwarya Shaji
Akanksha Verma
Ashima Bhaskar
Ved Prakash Dwivedi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608104

4,655 views
1 citation

Brief Research Report

Published on 28 Jul 2025

Hypertension attenuates COVID-19 vaccine protection in elderly patients: a retrospective cohort study

in Vaccines and Molecular Therapeutics

Zhen Yuan
Iong Fong Wong
Ren-He Xu
Xiao Zhan Zhang
Chon Lok Lei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612205

2,719 views

Original Research

Published on 28 Jul 2025

Mixed lipopeptide-based mucosal vaccine elicits a long-term bone marrow memory response that is potentially cross-reactive against a broad-spectrum of coronaviruses in mice

in Vaccines and Molecular Therapeutics

Raj S. Patel
Babita Agrawal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1619882

3,142 views
1 citation

Original Research

Published on 25 Jul 2025

Integrating bioinformatics to explore HPV-31 and HPV-52 E6/E7 proteins: from structural analysis to antigenic epitope prediction

in Vaccines and Molecular Therapeutics

Qixue Cai
Yifan Feng
Wenbo Dong
Yanling Meng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561572

2,609 views

Original Research

Published on 24 Jul 2025

AS04 drives superior cross-protective antibody response by increased NOTCH signaling of dendritic cells and proliferation of memory B cells

in Vaccines and Molecular Therapeutics

Valentino D’Onofrio
Ana Carolina Santana
Marthe Pauwels
Gwenn Waerlop
Anthony Willems
Fien De Boever
Martin Müller
Peter Sehr
Tim Waterboer
Isabel Leroux-Roels

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623405

3,477 views
2 citations

Original Research

Published on 22 Jul 2025

Development and characterization of the genotype F attenuated mumps candidate strains

in Vaccines and Molecular Therapeutics

Hongtao Liu
Na Liu
Yueqiu Sun
Shuang Li
Hang Li
Menghan Wang
Hui Shuang
Yan Cai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629585

2,230 views

Original Research

Published on 22 Jul 2025

Non-cognate ligands of hepatitis C virus envelope broadly neutralizing antibodies induce virus-neutralizing sera in mice

in Vaccines and Molecular Therapeutics

Stephen Ian Walimbwa
Shiv Bharadwaj
Petr Kosztyu
Lucie Vankova
Milan Kuchar
Eliska Kopecna
Roman Effenberg
Lukas Drasar
Leona Raskova Kafkova
Petr Maly

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624299

2,720 views

Original Research

Published on 21 Jul 2025

MetE: a promising protective antigen for tuberculosis vaccine development

in Vaccines and Molecular Therapeutics

Salem Salman Almujri
Elena Stylianou
Annalisa Nicastri
Iman Satti
Marcellus Korompis
Shuailin Li
Christopher J. De Voss
Marco Polo Peralta Alvarez
Rachel Tanner
Paulo J. G. Bettencourt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593263

3,865 views
2 citations

Original Research

Published on 17 Jul 2025

Immune memory reactivation and T cell dynamics following 12-month homologous CoronaVac booster: a longitudinal cohort study

in Vaccines and Molecular Therapeutics

Xinran Song
Weixin Chen
Shuang Bai
Min Lv
Jian Wang
Ao Zhang
Jiang Wu
Wei Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636629

3,021 views
1 citation

Original Research

Published on 17 Jul 2025

Adjuvant combination and antigen multimerization shape neutralizing antibody and T cell responses to a SARS-CoV-2 RBD subunit vaccine

in Vaccines and Molecular Therapeutics

João Pedro da Silva Nunes
Mariângela de Oliveira Silva
Juliana de Souza Apostolico
Isabela Pazotti Daher
Rodolfo Ferreira Marques
Marcio Massao Yamamoto
Alexia Adrianne Venceslau Brito Carvalho
Maria Fernanda de Castro-Amarante
Edison Luiz Durigon
Carsten Wrenger

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610422

3,413 views

Clinical Trial

Published on 17 Jul 2025

Immunogenicity and safety study of 23-valent pneumococcal polysaccharide vaccine revaccination among elderly individuals aged 60–70 years in Shanghai, China

in Vaccines and Molecular Therapeutics

Jing Qiu
Zhi Li
Fang Huang
Zhuoying Huang
Xiufang Liang
Juan Li
Yuting Liao
Xiang Guo
Xiaodong Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623611

3,030 views

Original Research

Published on 17 Jul 2025

Comparison of SARS-CoV-2 immune responses following vaccination with Comirnaty (Pfizer) and Vaxzevria (AstraZeneca) in healthy individuals with or without prior SARS-CoV-2 infection

in Vaccines and Molecular Therapeutics

Zdzisława Kondera-Anasz
Emilia Justyna Morawiec
Roksana Duszkiewicz
Filip Hajdrowski
Andrzej Wiczkowski

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612288

2,606 views
1 citation

Original Research

Published on 16 Jul 2025

Study of dense granule proteins in Eimeria spp. identifies a limited repertoire with potential as vaccine candidates

in Vaccines and Molecular Therapeutics

Gonzalo Sanchez-Arsuaga
Damer P. Blake
Fiona M. Tomley
Virginia Marugan-Hernandez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605984

2,334 views
1 citation

Original Research

Published on 16 Jul 2025

IL-2 and IL-15 augment HBV therapeutic vaccination and PD1 blockade for functional cure in the AAV-HBV mouse model

in Vaccines and Molecular Therapeutics

Gavin Lewis
Kirsten Malo
Thomas Rowland
Jenaya Hooks
Hao Yuan Liu
Sonam Popli
George Kukolj
Craig S. Pace

Frontiers in Immunology

doi 10.3389/fimmu.2025.1562107

3,418 views

Original Research

Published on 15 Jul 2025

Neutralizing antibody response to Omicron subvariants BA.1 and BA.5 in children and adolescents following the two-dose CoronaVac protocol (Immunita-002, Brazil): a 12-month longitudinal study

in Vaccines and Molecular Therapeutics

Camila Amormino Corsini
Guilherme Rodrigues Fernandes Campos
Priscila Fernanda da Silva Martins
Priscilla Soares Filgueiras
Ana Esther de Souza Lima
Sarah Vieira Contin Gomes
Caroline De Almeida Leitao Curimbaba
Daniela Aparecida Lorencini
Eolo Morandi Junior
Victor Mattos da Silva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589733

2,743 views

Original Research

Published on 15 Jul 2025

Comparison of SARS-CoV-2 IgG responses in hemodialysis patients and healthcare workers after COVID-19 vaccination

in Vaccines and Molecular Therapeutics

Hakkı Öztürk
Metin Özsoy
Ayşegül Tuna
Artuner Varlibas
Salih Cesur
Altan Aksoy
Aydın Çifci
Mehmet Emin Demir

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586468

2,110 views

Original Research

Published on 14 Jul 2025

Promotion of HIV clearance by sensitization of HIV reservoirs to cell death

in Vaccines and Molecular Therapeutics

Min Li
Baichao Sun
Jing Dong
Jian-Rong Li
Laurie J. Minze
Min Chen
Chao Cheng
Jin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600741

3,216 views

3,192 articles

articles

Neutralizing antibody response to different COVID-19 vaccines in Brazil: the impact of previous infection and booster doses

Evaluation of the viability and functionality of human peripheral blood mononuclear cells cryopreserved up to 2 years in animal-protein-free freezing media compared to the FBS-supplemented reference medium

Autovaccine immunoprophylaxis in patients with neurogenic bladder experiencing recurrent urinary tract infections

The immunogenicity and safety of an inactivated quadrivalent influenza vaccine and a 23-valent pneumococcal polysaccharide vaccine in individuals with chronic diseases

Dose-sparing effects of novel adjuvants and aluminum hydroxide on two different vaccines in a neonatal mouse model

Fc-modification of anti-PcrV gene-encoded antibodies modulates complement-mediated killing of Pseudomonas aeruginosa

MDSC depletion during immunization with heat-killed Mycobacterium tuberculosis increases protection against BCG infection

BCG and beyond: unlocking new frontiers in TB vaccine development

Hypertension attenuates COVID-19 vaccine protection in elderly patients: a retrospective cohort study

Mixed lipopeptide-based mucosal vaccine elicits a long-term bone marrow memory response that is potentially cross-reactive against a broad-spectrum of coronaviruses in mice

Integrating bioinformatics to explore HPV-31 and HPV-52 E6/E7 proteins: from structural analysis to antigenic epitope prediction

AS04 drives superior cross-protective antibody response by increased NOTCH signaling of dendritic cells and proliferation of memory B cells

Development and characterization of the genotype F attenuated mumps candidate strains

Non-cognate ligands of hepatitis C virus envelope broadly neutralizing antibodies induce virus-neutralizing sera in mice

MetE: a promising protective antigen for tuberculosis vaccine development

Immune memory reactivation and T cell dynamics following 12-month homologous CoronaVac booster: a longitudinal cohort study

Adjuvant combination and antigen multimerization shape neutralizing antibody and T cell responses to a SARS-CoV-2 RBD subunit vaccine

Immunogenicity and safety study of 23-valent pneumococcal polysaccharide vaccine revaccination among elderly individuals aged 60–70 years in Shanghai, China

Comparison of SARS-CoV-2 immune responses following vaccination with Comirnaty (Pfizer) and Vaxzevria (AstraZeneca) in healthy individuals with or without prior SARS-CoV-2 infection

Study of dense granule proteins in Eimeria spp. identifies a limited repertoire with potential as vaccine candidates

IL-2 and IL-15 augment HBV therapeutic vaccination and PD1 blockade for functional cure in the AAV-HBV mouse model

Neutralizing antibody response to Omicron subvariants BA.1 and BA.5 in children and adolescents following the two-dose CoronaVac protocol (Immunita-002, Brazil): a 12-month longitudinal study

Comparison of SARS-CoV-2 IgG responses in hemodialysis patients and healthcare workers after COVID-19 vaccination

Promotion of HIV clearance by sensitization of HIV reservoirs to cell death