Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Published on 23 Jun 2025

Characterization of the clinical relevance and hypoallergenic peptides of the newly evidenced major allergen Hum j 1

in Vaccines and Molecular Therapeutics

Ya-Li Cheng
Qiong Li
Yong-Shi Yang
Yi-Bo Hou
Zhi-Qiang Xu
Ji-Fu Wei
Jin-Lyu Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588870

2,402 views

Original Research

Published on 23 Jun 2025

Correlation between microneutralization test and a multiplexed immunoassay for evaluation of monkeypox and vaccinia virus antibodies before and after smallpox vaccination

in Vaccines and Molecular Therapeutics

Serena Marchi
Giulia Piccini
Edmond J. Remarque
Giulia Roscia
Bianca Semplici
Paolo Cantaloni
Noemi Guerrini
Roberta Zannella
Rosa Coluccio
Linda Benincasa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585284

3,002 views
3 citations

Original Research

Published on 20 Jun 2025

Comparison of homologous and heterologous vaccination strategies for combating disease caused by Burkholderia pseudomallei

in Vaccines and Molecular Therapeutics

Sergei S. Biryukov
Christopher K. Cote
Christopher P. Klimko
Jennifer L. Dankmeyer
Nathaniel O. Rill
Melissa Hunter
Michael L. Davies
Zander M. Hedrick
Jennifer L. Shoe
Lindsey K. Schmidt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596265

2,116 views

Original Research

Published on 20 Jun 2025

GMMA-based vaccine candidates against invasive nontyphoidal salmonellosis elicit bactericidal antibodies against a panel of epidemiologically relevant Salmonellae

in Vaccines and Molecular Therapeutics

Daniele De Simone
Marika Pinto
Maria Grazia Aruta
Marta Benincasa
Martina Carducci
Roberta Di Benedetto
Francesco Citiulo
Miren Iturriza
Elli Mylona
Stephen Baker

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610067

2,266 views
2 citations

Correction

Published on 19 Jun 2025

Correction: Tubeimuside I improves the efficacy of a therapeutic Fusobacterium nucleatum dendritic cell-based vaccine against colorectal cancer

in Vaccines and Molecular Therapeutics

Yanan Tong
Guoxiu Lu
Zhiguo Wang
Shanhu Hao
Guoxu Zhang
Hongwu Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639717

1,079 views

Original Research

Published on 19 Jun 2025

Circular mRNA-LNP vaccine encoding self-assembled E2-TMD-mi3 nanoparticles licit enhanced CSFV-specific immunity over commercial subunit vaccine

in Vaccines and Molecular Therapeutics

Chunxi Liu
Weifeng Zhai
Wenhao Nie
Conghao Zhong
Feifei Diao
Bo Yin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604677

3,249 views
2 citations

Perspective

Published on 18 Jun 2025

Immunogenicity of therapeutic peptide products: bridging the gaps regarding the role of product-related risk factors

in Vaccines and Molecular Therapeutics

Montserrat Puig
Sophie Shubow

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608401

5,249 views
9 citations

Original Research

Published on 18 Jun 2025

Epidemiological characteristics of breakthrough varicella cases among students in Jiulongpo District, Chongqing: implications for vaccination strategies

in Vaccines and Molecular Therapeutics

Huixian Zhou
Qianjin Long
Hechuan Xie
Yuan Yao
Chunyan Deng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1594598

2,398 views

Editorial

Published on 17 Jun 2025

Editorial: Nanoparticle-based delivery systems on immunomodulation

in Vaccines and Molecular Therapeutics

Pedro Augusto Carvalho Costa
Pedro Pires Goulart Guimaraes

Frontiers in Immunology

doi 10.3389/fimmu.2025.1626027

1,981 views

Original Research

Published on 16 Jun 2025

A novel and safe SmartCap® SC101 to develop the COVID-19 mRNA vaccine STP2104 inducing potent immune responses in humans

in Vaccines and Molecular Therapeutics

Rachel Kim
Tae-Gi Uhm
Jisu Kim
Dayeon Woo
Uk-Il Kim
Xue Meng
Byounggu Yang
Suhyeon Kim
Heejene Kim
Jonghyeon Kim

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571092

3,573 views

Review

Published on 16 Jun 2025

Immune responses to human papillomavirus infection and vaccination

in Vaccines and Molecular Therapeutics

Eunice Wavinya Kiamba
Martin R. Goodier
Ed Clarke

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591297

9,229 views
9 citations

Review

Published on 12 Jun 2025

T cells responses after vaccination: a regulatory perspective

in Vaccines and Molecular Therapeutics

Alessandra Buoninfante
Marco Cavaleri

Frontiers in Immunology

doi 10.3389/fimmu.2025.1584738

4,795 views
2 citations

Review

Published on 10 Jun 2025

Nanoparticle approaches for manipulating cytokine delivery and neutralization

in Vaccines and Molecular Therapeutics

Rui Wang
Luke J. Kubiatowicz
Runhe Zhang
Lin Bao
Ronnie H. Fang
Liangfang Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1592795

3,878 views
2 citations

Mini Review

Published on 10 Jun 2025

Research progress on composite nerve guidance conduits with immune-regulatory functions

in Vaccines and Molecular Therapeutics

Shuxuan Zhang
Xinyue Sun
Xuewa Yang
Yulan Fan
Yuxin Liang
Jiaying Li
Jue Ling

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622508

3,531 views

Review

Published on 09 Jun 2025

The immunological impact of revaccination in a hybrid-immune world

in Vaccines and Molecular Therapeutics

Mary Bausch-Jurken
Galit Alter

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588259

4,144 views
2 citations

Original Research

Published on 09 Jun 2025

Discovery and development of a safe and efficient COVID-19 mRNA vaccine, STP2104, using a novel capping library screening method

in Vaccines and Molecular Therapeutics

Kanghyun Choi
Joo-Young Lee
Uk-Il Kim
So-Hyun Park
So-Hee Hong
Yoo-Jin Bang
Yun-Ho Hwang
Jong-Eun Lee
Suhyun Park
Soochong Kim

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571713

4,824 views
1 citation

Review

Published on 09 Jun 2025

Atherosclerosis: from lipid-lowering and anti-inflammatory therapies to targeting arterial retention of ApoB-containing lipoproteins

in Vaccines and Molecular Therapeutics

Gala Araujo
Leidy Marian Valencia
Agata Martin-Ozimek
Yosdel Soto
Spencer D. Proctor

Frontiers in Immunology

doi 10.3389/fimmu.2025.1485801

6,115 views
5 citations

Original Research

Published on 06 Jun 2025

Immune response dynamics of SARS-CoV-2 vaccination in chronic lymphocytic leukemia individuals: a descriptive analysis

in Vaccines and Molecular Therapeutics

Clara Sánchez-Menéndez
Alejandro Zurdo
Magdalena Corona
Elena Mateos de la Morenas
Sara Rodríguez-Mora
Guiomar Casado
Javier García-Pérez
Mayte Pérez-Olmeda
Susana Domínguez
María Aránzazu Murciano-Antón

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571680

2,621 views

Review

Published on 06 Jun 2025

Recent advances on coxsackievirus A6 vaccine research

in Vaccines and Molecular Therapeutics

Xianfeng Zhou
Han Mo
Hui Li
Fenglan He
Qian Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1603028

5,482 views
3 citations

Original Research

Published on 06 Jun 2025

Intramuscular DNA vaccine provides protection in non-human primate and mouse models of SARS-CoV-2

in Vaccines and Molecular Therapeutics

Subeena Sood
Ebony N. Gary
Majed Matar
Jessica Kim
Casey E. Hojecki
Bryce Warner
Robert Vendramelli
Thang Truong
Alanna Smith
Jennifer Rice

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589584

2,275 views
1 citation

Original Research

Published on 05 Jun 2025

In silico multi-epitope-based vaccine design for Mycobacterium avium complex species

in Vaccines and Molecular Therapeutics

Leah Kashiri
Wonderful T. Choga
Tinashe Musasa
Pasipanodya Nziramasanga
Rutendo B. Gutsire
Lynn S. Zijenah
Norman L. Mukarati
Simani Gaseitsiwe
Sikhulile Moyo
Nyasha Chin’ombe

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589083

3,225 views

Original Research

Published on 05 Jun 2025

An RNA vaccine against adrenomedullin reduces angiogenesis and tumor burden in a syngeneic metastatic melanoma mouse model

in Vaccines and Molecular Therapeutics

Srdan Tadic
Laura Ochoa-Callejero
Judit Narro-Íñiguez
Josune García-Sanmartín
Alfredo Martínez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604156

3,893 views
4 citations

Original Research

Published on 05 Jun 2025

Construction and evaluation of a Salmonella minicell-based dendritic cell-targeted multi-epitope vaccine against Helicobacter pylori

in Vaccines and Molecular Therapeutics

Jiaxue Yang
Kehan Chen
Yalan Zhu
Tiancheng Xie
Chubin Fang
Chuan Wang
Tian Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595096

3,156 views
1 citation

Original Research

Published on 05 Jun 2025

The fusion subunit vaccine L-DBF protects aged mice against heterologous lethal Shigella challenge after prior exposure

in Vaccines and Molecular Therapeutics

Md Shafiullah Parvej
Ti Lu
Suhrid Maiti
Zackary K. Dietz
Debaki R. Howlader
Mst Nusrat Zahan
Alexa Cato
Satabdi Biswas
William D. Picking
Wendy L. Picking

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586537

2,202 views
1 citation