Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Published on 02 Jan 2026

Temporal dynamics of SARS-CoV-2 antibodies and IgG subclasses following multiple doses and diverse COVID-19 vaccine combinations

in Vaccines and Molecular Therapeutics

Julia Meyer
Achim Hoerauf
Aleksandra Elzbieta Dubiel
Peđa Kovačević
Anika Trudić
Dragan Primorac
Marc P. Hübner
Tomabu Adjobimey
Marijo Parcina

Frontiers in Immunology

doi 10.3389/fimmu.2025.1727049

2,110 views
1 citation

Original Research

Published on 02 Jan 2026

Low maternal pertussis protection and quantified infant risk: supporting maternal Tdap vaccination in China

in Vaccines and Molecular Therapeutics

Wen Wang
Tingting Zhang
Xiang Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1687663

1,039 views

Original Research

Published on 18 Dec 2025

T cell immunity to seasonal Influenza A and H5N1 viruses in laboratory workers receiving annual seasonal Influenza vaccines

in Vaccines and Molecular Therapeutics

Joel Sop
Tyler P. Beckey
Lizeth Gutierrez
Li Zhang
Kelly A. Gebo
Kellie N. Smith
Joel N. Blankson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1718805

1,778 views

Original Research

Published on 17 Dec 2025

Bioinformatic and experimental identification and characterization of Clostridioides difficile lipoproteins as potential vaccine candidates

in Vaccines and Molecular Therapeutics

Soumyadeep Chakraborty
Joshua Heuler
Shaohui Wang
Junling Qin
Adrit Roy
Lubem Nathanel Agbendeh
Anastasia Tomatsidou
Hyeun Bum Kim
Xingmin Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650364

1,061 views

Original Research

Published on 17 Dec 2025

Chronic opioid use is associated with higher antibody response to influenza vaccination in people living with HIV

in Vaccines and Molecular Therapeutics

Christine M. Dang
C. Mindy Nelson
Rajendra N. Pahwa
Hansel E. Tookes
Daniel J. Feaster
Prabhsimran Singh
Allan E. Rodriguez
David W. Forrest
Nobuyo Nakamura
Priya P. Ghanta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686103

1,448 views

Original Research

Published on 17 Dec 2025

OmniNeo: a multi-omics pipeline incorporating proteomics and AI selection for neoantigen optimization in tumor immunotherapy

in Vaccines and Molecular Therapeutics

Manman Lu
Yang Liu
Linfeng Xu
Yuan Gao
Peng Liu
Zhenhao Liu
Xiaoxiu Tan
Wenzhen Li
Yong Lin
Lanming Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1727642

1,966 views

Perspective

Published on 16 Dec 2025

Vaccination in the post-COVID era: lessons to be learned in Latin America

in Vaccines and Molecular Therapeutics

Luis Del Carpio-Orantes
Gabriela Zambrano-Sánchez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726836

1,339 views

Original Research

Published on 12 Dec 2025

A trans-activating transduction peptide fused nanobody targeting viral nonstructural protein NS4B inhibits bovine viral diarrhea virus replication

in Vaccines and Molecular Therapeutics

Bao Zhao
Zehao Lv
Wenqi Fan
Ying Zhang
Shuang Wei
Junyang Fang
Ni Huang
Xiwen Chen
Lizhen Wang
Xuefeng Qi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712683

1,155 views

Original Research

Published on 12 Dec 2025

Mono-WNV and combined WNV/TBEV inactivated vaccine efficacy against a wide range of WNV and TBEV strains

in Vaccines and Molecular Therapeutics

Ksenia Tuchynskaya
Mikhail Vorovitch
Yuriy Kruglov
Guzal Mostipanova
Ivan Kholodilov
Alla Ivanova
Victoria Kuchina
Anastasia Rogova
Galina Karganova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715371

940 views

Original Research

Published on 12 Dec 2025

Antibodies against polysaccharide type 3 and pneumococcal proteins demonstrate synergistic protective effect in a highly virulent type 3 invasive disease model in mice

in Vaccines and Molecular Therapeutics

Taylor C. Stevenson
Heidi Burke
Sara E. Roggensack
Anthony Pratt
Aquib Hossain
Pallab Ghosh
Gilles Besin
Yingjie Lu
Fan Zhang
Richard Malley

Frontiers in Immunology

doi 10.3389/fimmu.2025.1707686

1,857 views

Mini Review

Published on 12 Dec 2025

Marine-derived L-asparaginase: unlocking marine power in anti-tumor therapeutics

in Vaccines and Molecular Therapeutics

Ritika Gopalakrishnan
Kamala Kannan
Ragul Gunasekaran
Priya Ramachandran
Dhanraj Ganapathy
Pitchiah Sivaperumal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1710780

1,303 views

Systematic Review

Published on 11 Dec 2025

Incidence, risk factors and outcomes of BCGosis following BCG vaccination in infants: a systematic review and meta-analyses

in Vaccines and Molecular Therapeutics

Fathima Raahima Riyas Mohamed
Mudasar Nisar
Ismail Saeed
Mohammed Rushdhi Irfan
Ahlaam Khalid
Muneeb Faiz
Ahmed F. Younis
Shahan Javed
Arya Sen
Asma Azam

Frontiers in Immunology

doi 10.3389/fimmu.2025.1615039

2,004 views

Brief Research Report

Published on 11 Dec 2025

Plasmodium vivax infection-driven modulation of sterol carrier protein reveals a metabolic link to reproductive physiology in Anopheles stephensi

in Vaccines and Molecular Therapeutics

Seena Kumari
Pooja Yadav
Nirmala Sankhala
Jyoti Rani
Gunjan Sharma
Charu Chauhan
Sanjay Tevatiya
Rajnikant Dixit

Frontiers in Immunology

doi 10.3389/fimmu.2025.1703479

1,383 views

Review

Published on 10 Dec 2025

Glycosylation as a strategic mechanism for measles virus and mumps virus immune evasion

in Vaccines and Molecular Therapeutics

Catalina Galvan
Inna G. Ovsyannikova
Richard B. Kennedy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716829

1,910 views

Systematic Review

Published on 10 Dec 2025

A bibliometric analysis of vaccine research on Chikungunya virus: contributors, trends, and emerging frontiers

in Vaccines and Molecular Therapeutics

Da Shao
Zengwei Kou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692556

2,014 views

Editorial

Published on 09 Dec 2025

Editorial: Enhancing CAR T-cell therapy with imaging

in Vaccines and Molecular Therapeutics

Egesta Lopci
Dorine de Jong
Laurent Dercle

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705002

717 views

Original Research

Published on 08 Dec 2025

Cross-species analysis of FcγRIIa/b (CD32a/b) polymorphisms at position 131: structural and functional insights into the mechanism of IgG- mediated phagocytosis in human and macaque

in Vaccines and Molecular Therapeutics

William D. Tolbert
Paula B. Nhan
Haleigh E. Conley
Xiaoxuan Ge
Monika Chandravanshi
Madeleine Lee
Julianna Veilleux
Marek Korzeniowski
Suneetha Gottumukkala
Margaret E. Ackerman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726068

1,308 views

Original Research

Published on 08 Dec 2025

Enhancing functional antibody responses against HIV envelope V1V2 through vaccine formulations

in Vaccines and Molecular Therapeutics

Clauvis Kunkeng Yengo
Xiaomei Liu
Gabriel Laghlali
Seok-Chan Park
Jéromine Klingler
Christina C. Luo
Xunqing Jiang
Xiang-Peng Kong
Priyanka G. Rao
Chitra Upadhyay

Frontiers in Immunology

doi 10.3389/fimmu.2025.1722596

1,985 views

Mini Review

Published on 08 Dec 2025

Development of human mycoplasma vaccines: navigating the IL-17A paradox

in Vaccines and Molecular Therapeutics

Wenjun Zhang
Tingting Li
Fangyi Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1720943

1,039 views

Original Research

Published on 08 Dec 2025

Molecular transmission network characteristics and high-risk transmission analysis of newly reported HIV-1 subjects in Nantong, China

in Vaccines and Molecular Therapeutics

Dongyang Wang
Xiaoyi Zhou
Tianze Yuan
Hongli Xia
Kai Liu
Anni Chen
Ping Zhu
Xun Zhuang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716273

1,065 views

Methods

Published on 05 Dec 2025

A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling

in Vaccines and Molecular Therapeutics

Valentina Di Salvatore
Federica Cernuto
Giulia Russo
Francesco Pappalardo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1628583

2,345 views

Original Research

Published on 05 Dec 2025

Design and immunogenicity of a quadrivalent mRNA vaccine targeting HSV-2 with comparative evaluation of co-formulated and admixed formulations

in Vaccines and Molecular Therapeutics

Youngran Cho
Chanwoo Lee
Sang-In Park
Yeongjun Kim
Yu-Sun Lee
Seonghyun Lee
Subin Yoon
Gahyun Roh
Dahyeon Ha
Ayoung Oh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1712691

4,586 views

Original Research

Published on 05 Dec 2025

An integrated immunoinformatic approach to design a novel multiepitope chimeric vaccine against Mycoplasma phocimorsus as a causal agent of bloodstream infections

in Vaccines and Molecular Therapeutics

Rongrong Yu
Ahmad Hasan
Muhammad Ibrahim
Wadi B. Alonazi
Li Bin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1719398

1,202 views

Mini Review

Published on 05 Dec 2025

Next-generation vaccines against bacterial pathogens: mRNA and beyond

in Vaccines and Molecular Therapeutics

Huimin Chen
Ye Gu
Lei Song
Lihui Si

Frontiers in Immunology

doi 10.3389/fimmu.2025.1709794

3,266 views

3,191 articles

articles

Temporal dynamics of SARS-CoV-2 antibodies and IgG subclasses following multiple doses and diverse COVID-19 vaccine combinations

Low maternal pertussis protection and quantified infant risk: supporting maternal Tdap vaccination in China

T cell immunity to seasonal Influenza A and H5N1 viruses in laboratory workers receiving annual seasonal Influenza vaccines

Bioinformatic and experimental identification and characterization of Clostridioides difficile lipoproteins as potential vaccine candidates

Chronic opioid use is associated with higher antibody response to influenza vaccination in people living with HIV

OmniNeo: a multi-omics pipeline incorporating proteomics and AI selection for neoantigen optimization in tumor immunotherapy

Vaccination in the post-COVID era: lessons to be learned in Latin America

A trans-activating transduction peptide fused nanobody targeting viral nonstructural protein NS4B inhibits bovine viral diarrhea virus replication

Mono-WNV and combined WNV/TBEV inactivated vaccine efficacy against a wide range of WNV and TBEV strains

Antibodies against polysaccharide type 3 and pneumococcal proteins demonstrate synergistic protective effect in a highly virulent type 3 invasive disease model in mice

Marine-derived L-asparaginase: unlocking marine power in anti-tumor therapeutics

Incidence, risk factors and outcomes of BCGosis following BCG vaccination in infants: a systematic review and meta-analyses

Plasmodium vivax infection-driven modulation of sterol carrier protein reveals a metabolic link to reproductive physiology in Anopheles stephensi

Glycosylation as a strategic mechanism for measles virus and mumps virus immune evasion

A bibliometric analysis of vaccine research on Chikungunya virus: contributors, trends, and emerging frontiers

Editorial: Enhancing CAR T-cell therapy with imaging

Cross-species analysis of FcγRIIa/b (CD32a/b) polymorphisms at position 131: structural and functional insights into the mechanism of IgG- mediated phagocytosis in human and macaque

Enhancing functional antibody responses against HIV envelope V1V2 through vaccine formulations

Development of human mycoplasma vaccines: navigating the IL-17A paradox

Molecular transmission network characteristics and high-risk transmission analysis of newly reported HIV-1 subjects in Nantong, China

A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling

Design and immunogenicity of a quadrivalent mRNA vaccine targeting HSV-2 with comparative evaluation of co-formulated and admixed formulations

An integrated immunoinformatic approach to design a novel multiepitope chimeric vaccine against Mycoplasma phocimorsus as a causal agent of bloodstream infections

Next-generation vaccines against bacterial pathogens: mRNA and beyond