Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Published on 17 Jul 2025

Comparison of SARS-CoV-2 immune responses following vaccination with Comirnaty (Pfizer) and Vaxzevria (AstraZeneca) in healthy individuals with or without prior SARS-CoV-2 infection

in Vaccines and Molecular Therapeutics

Zdzisława Kondera-Anasz
Emilia Justyna Morawiec
Roksana Duszkiewicz
Filip Hajdrowski
Andrzej Wiczkowski

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612288

2,209 views
1 citation

Original Research

Published on 16 Jul 2025

IL-2 and IL-15 augment HBV therapeutic vaccination and PD1 blockade for functional cure in the AAV-HBV mouse model

in Vaccines and Molecular Therapeutics

Gavin Lewis
Kirsten Malo
Thomas Rowland
Jenaya Hooks
Hao Yuan Liu
Sonam Popli
George Kukolj
Craig S. Pace

Frontiers in Immunology

doi 10.3389/fimmu.2025.1562107

3,091 views

Original Research

Published on 16 Jul 2025

Study of dense granule proteins in Eimeria spp. identifies a limited repertoire with potential as vaccine candidates

in Vaccines and Molecular Therapeutics

Gonzalo Sanchez-Arsuaga
Damer P. Blake
Fiona M. Tomley
Virginia Marugan-Hernandez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605984

2,031 views

Original Research

Published on 15 Jul 2025

Comparison of SARS-CoV-2 IgG responses in hemodialysis patients and healthcare workers after COVID-19 vaccination

in Vaccines and Molecular Therapeutics

Hakkı Öztürk
Metin Özsoy
Ayşegül Tuna
Artuner Varlibas
Salih Cesur
Altan Aksoy
Aydın Çifci
Mehmet Emin Demir

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586468

1,931 views

Original Research

Published on 15 Jul 2025

Neutralizing antibody response to Omicron subvariants BA.1 and BA.5 in children and adolescents following the two-dose CoronaVac protocol (Immunita-002, Brazil): a 12-month longitudinal study

in Vaccines and Molecular Therapeutics

Camila Amormino Corsini
Guilherme Rodrigues Fernandes Campos
Priscila Fernanda da Silva Martins
Priscilla Soares Filgueiras
Ana Esther de Souza Lima
Sarah Vieira Contin Gomes
Caroline De Almeida Leitao Curimbaba
Daniela Aparecida Lorencini
Eolo Morandi Junior
Victor Mattos da Silva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589733

2,431 views

Original Research

Published on 14 Jul 2025

Promotion of HIV clearance by sensitization of HIV reservoirs to cell death

in Vaccines and Molecular Therapeutics

Min Li
Baichao Sun
Jing Dong
Jian-Rong Li
Laurie J. Minze
Min Chen
Chao Cheng
Jin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600741

2,885 views

Original Research

Published on 11 Jul 2025

Comparative transcriptomic analysis of mouse macrophages infected with live attenuated vaccine strains of Mycobacterium tuberculosis

in Vaccines and Molecular Therapeutics

Raja Veerapandian
Barbara Yang
Areanna Carmona
Melina J. Sedano
Victoria Reid
Rodrigo Jimenez
Jessica Chacon
Chinnaswamy Jagannath
Enrique I. Ramos
Shrikanth S. Gadad

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583439

3,442 views

Original Research

Published on 10 Jul 2025

Single-cycle, pseudotyped reporter influenza virus to facilitate evaluation of treatment strategies for avian influenza, Ebola and other highly infectious diseases in vivo

in Vaccines and Molecular Therapeutics

Tiong Kit Tan
Pramila Rijal
Kuan-Ying A. Huang
Stephen C. Hyde
Deborah R. Gill
Alain R. Townsend

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608074

3,319 views
2 citations

Original Research

Published on 08 Jul 2025

Immuno-informatics analyses of important esophageal cancer associated viruses for multi-epitope vaccine design

in Vaccines and Molecular Therapeutics

Zafer Saad Al Shehri

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587224

3,429 views

Original Research

Published on 04 Jul 2025

The TNFα-binding domain of the therapeutic antibody adalimumab elicits CD4 T-cell responses in rheumatoid arthritis patients

in Vaccines and Molecular Therapeutics

Mateusz Makuch
Josine van Beek
Carla A. Wijbrandts
Marja Aalbers
Philippe Stas
Alexander B. Meijer
Anja ten Brinke
Theo Rispens
Paul Peter Tak
Gertjan Wolbink

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549781

3,000 views

Original Research

Published on 04 Jul 2025

Dynamics of HBsAb persistence and associated BCR IgG-H CDR3 repertoire features in ultra-high versus extremely low responders to HBV vaccination

in Vaccines and Molecular Therapeutics

Ting-Wen Yang
Li-Na Sun
Ting Zhang
Yu-Rong Pan
Jun Li
Yang-Yang Li
Zhi-Yong Han
Wan-Bang Sun
Xin-Sheng Yao
Xiao-Yan He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587553

2,332 views

Original Research

Published on 04 Jul 2025

Screening of novel therapeutic targets and chimeric vaccine construction against antibiotic-resistant Yersinia Enterocolitica

in Vaccines and Molecular Therapeutics

Mohibullah Shah
Rouman Fatima
Asifa Sarfraz
Muhammad Umer Khan
Hasan Ejaz
Maqsood Alam
Shahid Aziz
Umar Nishan
Abid Ali
Ahmed Bari

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555248

3,021 views
1 citation

Original Research

Published on 03 Jul 2025

PepSeq as a highly multiplexed platform for melioidosis antigen discovery and vaccine development

in Vaccines and Molecular Therapeutics

Evan A. Elko
Charles H. D. Williamson
Heather R. Green
Marcellene A. Gates-Hollingsworth
Georgia A. Nelson
Sujata G. Pandit
Heather L. Mead
Christopher Allender
Celeste Woerle
Mark Mayo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605758

2,450 views
1 citation

Original Research

Published on 01 Jul 2025

Quantitative bead–based multiplex assay for simultaneous determination of IgG concentrations of pertussis toxin, filamentous hemagglutinin, pertactin, diphtheria, tetanus, Haemophilus influenzae b, and hepatitis B in human serum samples

in Vaccines and Molecular Therapeutics

Vishal Rathod
Sagar Katke
Sumant Patil
Sachin Bhandare
Laxmikant Kadam
Manish Gautam
Prabhu Gumma
Krishna Manoj Kumar
Laura Hassall
Cathy Asokanathan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587567

3,276 views
1 citation

Original Research

Published on 01 Jul 2025

The F1F3 recombinant chimera induced higher vaccine efficacy than its independent F1 and F3 components against Leishmania (L.) infantum chagasi mice infection

in Vaccines and Molecular Therapeutics

Daniele Crespo Gomes
Maria Paula Fonseca-Ribeiro
Marcus Vinicius Alves-Silva
Clarisa B. Palatnik-de-Sousa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598755

2,145 views

Original Research

Published on 30 Jun 2025

Influenza-specific antibody-mediated and complement-dependent cellular cytotoxicity-inducing antibodies in vaccinated and infected pigs

in Vaccines and Molecular Therapeutics

Mithilesh Singh
Gabriela Mansano do Nascimento
Sankar Renu
Dina Bugybayeva
Olaitan C. Shekoni
Raksha Suresh
Jennifer Schrock
Sara Dolatyabi
Diego G. Diel
Prosper N. Boyaka

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600761

3,294 views

Correction

Published on 30 Jun 2025

Correction: Development of a subunit vaccine against the cholangiocarcinoma causing Opisthorchis viverrini: a computational approach

in Vaccines and Molecular Therapeutics

Mohibullah Shah
Farva Sitara
Asifa Sarfraz
Muhammad Shehroz
Tehreem Ul Wara
Asia Perveen
Najeeb Ullah
Aqal Zaman
Umar Nishan
Sarfraz Ahmed

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638914

1,029 views

Brief Research Report

Published on 27 Jun 2025

Pre-clinical allergenicity assessment of IgE epitope-targeted Der p 2 mutants demonstrate potential as hypoallergenic AIT candidates

in Vaccines and Molecular Therapeutics

Glorismer Pena-Amelunxen
Mohadeseh Asghari
Kriti Khatri
Jill Glesner
Serge A. Versteeg
Ronald van Ree
Martin D. Chapman
Scott A. Smith
Maksymilian Chruszcz
Anna Pomés

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623920

2,723 views

Original Research

Published on 26 Jun 2025

Nanolipoprotein particle (NLP) vaccine confers protection against Yersinia pestis aerosol challenge in a BALB/c mouse model

in Vaccines and Molecular Therapeutics

Sergei S. Biryukov
Amy Rasley
Michael L. Davies
Christopher P. Klimko
Jennifer L. Dankmeyer
Melissa Hunter
Nathaniel O. Rill
Jennifer L. Shoe
Jeremy Miller
Yuli Talyansky

Frontiers in Immunology

doi 10.3389/fimmu.2025.1603710

3,368 views

Brief Research Report

Published on 26 Jun 2025

Sexual dimorphism-driven differences are overcome in a preclinical vaccine model against Trypanosoma cruzi

in Vaccines and Molecular Therapeutics

Camila Bulfoni Balbi
Maria Florencia Pacini
Brenda Dinatale
Cecilia Farré
Paula Cacik
Estefanía Prochetto
Florencia Belén González
Iván Marcipar
Gabriel Cabrera
Ana Rosa Pérez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526573

2,304 views

Original Research

Published on 26 Jun 2025

A consensus mathematical model of vaccine-induced antibody dynamics for multiple vaccine platforms and pathogens

in Vaccines and Molecular Therapeutics

Kristen M. Wilding
Carmen Molina-París
Jessica Z. Kubicek-Sutherland
Benjamin McMahon
Alan S. Perelson
Ruy M. Ribeiro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596518

3,457 views

Brief Research Report

Published on 25 Jun 2025

Immune responses following DNA vaccination by needle-free injection against Burkholderia pseudomallei hemolysin co-regulated protein 1

in Vaccines and Molecular Therapeutics

Michael L. Davies
Sergei S. Biryukov
Christopher P. Klimko
Jennifer L. Dankmeyer
Nathaniel O. Rill
Melissa Hunter
Christopher T. Braun
Deven W. Patrick
Tyrique D. David
Steven A. Kwilas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612540

1,852 views

Review

Published on 25 Jun 2025

Progress in combination vaccines and the co-administration of influenza virus and SARS-CoV-2 vaccines

in Vaccines and Molecular Therapeutics

Chengyu Hu
Chenguang Niu
Xiaohui Li
Ke He
Mengyu Li
Xiaonan Gao
Qiannan Wei
Weiyang Sun
Yongkun Zhao
Yuanguo Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578733

4,230 views

Review

Published on 24 Jun 2025

Melioidosis vaccines: recent advances and future directions

in Vaccines and Molecular Therapeutics

Sineenart Sengyee
Sarah B. Weiby
Ivory T. Rok
Mary N. Burtnick
Paul J. Brett

Frontiers in Immunology

doi 10.3389/fimmu.2025.1582113

3,290 views
2 citations

3,150 articles

articles

Comparison of SARS-CoV-2 immune responses following vaccination with Comirnaty (Pfizer) and Vaxzevria (AstraZeneca) in healthy individuals with or without prior SARS-CoV-2 infection

IL-2 and IL-15 augment HBV therapeutic vaccination and PD1 blockade for functional cure in the AAV-HBV mouse model

Study of dense granule proteins in Eimeria spp. identifies a limited repertoire with potential as vaccine candidates

Comparison of SARS-CoV-2 IgG responses in hemodialysis patients and healthcare workers after COVID-19 vaccination

Neutralizing antibody response to Omicron subvariants BA.1 and BA.5 in children and adolescents following the two-dose CoronaVac protocol (Immunita-002, Brazil): a 12-month longitudinal study

Promotion of HIV clearance by sensitization of HIV reservoirs to cell death

Comparative transcriptomic analysis of mouse macrophages infected with live attenuated vaccine strains of Mycobacterium tuberculosis

Single-cycle, pseudotyped reporter influenza virus to facilitate evaluation of treatment strategies for avian influenza, Ebola and other highly infectious diseases in vivo

Immuno-informatics analyses of important esophageal cancer associated viruses for multi-epitope vaccine design

The TNFα-binding domain of the therapeutic antibody adalimumab elicits CD4 T-cell responses in rheumatoid arthritis patients

Dynamics of HBsAb persistence and associated BCR IgG-H CDR3 repertoire features in ultra-high versus extremely low responders to HBV vaccination

Screening of novel therapeutic targets and chimeric vaccine construction against antibiotic-resistant Yersinia Enterocolitica

PepSeq as a highly multiplexed platform for melioidosis antigen discovery and vaccine development

Quantitative bead–based multiplex assay for simultaneous determination of IgG concentrations of pertussis toxin, filamentous hemagglutinin, pertactin, diphtheria, tetanus, Haemophilus influenzae b, and hepatitis B in human serum samples

The F1F3 recombinant chimera induced higher vaccine efficacy than its independent F1 and F3 components against Leishmania (L.) infantum chagasi mice infection

Influenza-specific antibody-mediated and complement-dependent cellular cytotoxicity-inducing antibodies in vaccinated and infected pigs

Correction: Development of a subunit vaccine against the cholangiocarcinoma causing Opisthorchis viverrini: a computational approach

Pre-clinical allergenicity assessment of IgE epitope-targeted Der p 2 mutants demonstrate potential as hypoallergenic AIT candidates

Nanolipoprotein particle (NLP) vaccine confers protection against Yersinia pestis aerosol challenge in a BALB/c mouse model

Sexual dimorphism-driven differences are overcome in a preclinical vaccine model against Trypanosoma cruzi

A consensus mathematical model of vaccine-induced antibody dynamics for multiple vaccine platforms and pathogens

Immune responses following DNA vaccination by needle-free injection against Burkholderia pseudomallei hemolysin co-regulated protein 1

Progress in combination vaccines and the co-administration of influenza virus and SARS-CoV-2 vaccines

Melioidosis vaccines: recent advances and future directions