Frontiers in Immunology | Viral Immunology

Original Research

Published on 30 May 2025

Comprehensive transcriptome assessment in PBMCs of post-COVID patients at a median follow-up of 28 months after a mild COVID infection reveals upregulation of JAK/STAT signaling and a prolonged immune response

in Viral Immunology

Serena Fineschi
Joakim Klar
Juan Ramon Lopez Egido
Jens Schuster
Jonas Bergquist
René Kaden
Niklas Dahl

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589589

8,223 views
4 citations

Original Research

Published on 29 May 2025

Patrolling monocytes mediate virus neutralizing IgG effector functions: beyond neutralization capacity

in Viral Immunology

Abdelrahman Elwy
Swati Dhiman
Hossam Abdelrahman
Julia Specht
Theresa Charlotte Christ
Julia Falkenstein
Harpreet Kaur
Lisa Holnsteiner
Judith Lang
Matthias Mack

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600056

2,269 views

Original Research

Published on 29 May 2025

Dynamic alterations of circulating lymphocytes during the trajectory of Hantaan virus-induced hemorrhagic fever with renal syndrome

in Viral Immunology

Lin Su
Shuangjuan Liu
Lei Shi
Yuan Cheng
Juanjuan Gao
Ruirui Guo
Yinli He
Linpei Zhang
Tianyan Chen
Jinsong Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567306

2,204 views

Original Research

Published on 29 May 2025

Causal relationship between hepatic function indicators and thrombocytopenia risk in early-stage hepatitis B virus infection: evidence from clinical observational studies and mendelian randomization analyses

in Viral Immunology

Tian-bin Chen
Jian-wei Jiang
Hong-yan Guo
Xiao-tong Chen
Shuai Zhi
Yu-hai Hu
Ya Fu
Yong-bing Zeng
Can Liu
Qi-shui Ou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1440317

3,415 views

Original Research

Published on 29 May 2025

A nomogram for predicting unfavorable outcomes of antituberculosis treatment among individuals with AIDS combined with pulmonary tuberculosis in China

in Viral Immunology

Xiaoxu Han
Jin Sun
Yuan Gao
Hongxia Yan
Xiangchuan He
Yuanyuan Ma
Peng Xu
Ning Ding
Xin Zhang
Meixin Ren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1594107

2,515 views

Mini Review

Published on 23 May 2025

Mitochondrial metabolic rescue in post-COVID-19 syndrome: MR spectroscopy insights and precision nutritional therapeutics

in Viral Immunology

Li-zhen Chen
Qi Cai
Peng-fei Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597370

7,173 views
6 citations

Original Research

Published on 22 May 2025

Comparative analysis of neutrophil dynamics and disease in SARS-CoV-2 Delta and Omicron variants utilizing an in vivo feline model for COVID-19

in Viral Immunology

Sachithra Gunasekara
Shoroq Shatnawi
Sunil More
Breya Ludwig
Sai Narayanan
Miruthula Tamil Selvan
Craig A. Miller
Jennifer M. Rudd

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547918

3,260 views

Original Research

Published on 22 May 2025

CD4+ T cell recognition of HIV-1 alternate reading frame proteins

in Viral Immunology

Joel Sop
Tyler P. Beckey
Joel N. Blankson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600132

1,782 views

Original Research

Published on 22 May 2025

Multiomics analysis unveils key biomarkers during dynamic progress of IAV infection in mice

in Viral Immunology

Huan Lei
Yixi Xu
Hao Zhang
Bin Zhang
Wenjun Luo
Xiao Liu
Haijun Zhang
Jinming Yang
Wen Wen
Ping Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566690

3,628 views
2 citations

Original Research

Published on 21 May 2025

Predominant T-cell epitopes of SARS-CoV-2 restricted by multiple prevalent HLA-B and HLA-C allotypes in Northeast Asia

in Viral Immunology

Yu Zhao
Min Peng
Chengtao He
Min Li
Xuelian Han
Qiang Fu
Yandan Wu
Fangping Yue
Chunguang Yan
Guangyu Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545510

2,017 views

Original Research

Published on 21 May 2025

Neuroinflammation associated with proviral DNA persists in the brain of virally suppressed people with HIV

in Viral Immunology

Sarah J. Byrnes
Janna Jamal Eddine
Jingling Zhou
Emily Chalmers
Emma Wanicek
Narin Osman
Trisha A. Jenkins
Michael Roche
Bruce J. Brew
Jacob D. Estes

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570692

3,670 views
2 citations

Original Research

Published on 20 May 2025

Distribution and potential involvement of PTEN in the innate immune response during viral infections in Cherry Valley ducks

in Viral Immunology

Wende Chen
Shaojie Han
Rong Li
Shuo Li
Zhi Cao
Qing Pan
Gen Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570872

1,803 views

Original Research

Published on 20 May 2025

SIV/SARS-CoV-2 coinfection in rhesus macaques impacts viral shedding, host immunity, the microbiome, and viral evolution

in Viral Immunology

Megan N. Fredericks
Zohar Kolodner
Adam Waalkes
Kaitlin Sawatzki
Linhui Hao
Dustin R. Long
Kelsi Penewit
Cecily C. Midkiff
Carter J. McCormick
Semira Beraki

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587688

3,388 views
1 citation

Review

Published on 16 May 2025

Metabolic reprogramming in viral infections: the interplay of glucose metabolism and immune responses

in Viral Immunology

Mahmoud Darweesh
Saeed Mohammadi
Mina Rahmati
Moosa Al-Hamadani
Ahmed Al-Harrasi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578202

6,025 views
11 citations

Original Research

Published on 16 May 2025

Correlation between severe acute respiratory syndrome coronavirus 2 infection and serum anti-neutrophil cytoplasmic antibody formation

in Viral Immunology

Hao Huang
Yu-Jie Zang
Zheng-Guo Li
Qian Li
Chun-Yan Ma
Hai-Yuan Zhao
Hang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593577

2,035 views

Mini Review

Published on 16 May 2025

Estrogen and viral infection

in Viral Immunology

Xiangrui Wei
Longyan Hong
Hao Liang
Ke Ren
Wenqing Man
Yinghui Zhao
Pengbo Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1556728

4,142 views
1 citation

Original Research

Published on 16 May 2025

The protein interaction of mitochondrial transcription factors A and B2 is associated with 30-day survival in critical COVID-19

in Viral Immunology

Britta Westhus
Patrick Thon
Lars Palmowski
Katharina Rump
Björn Koos
Frederik Wiebel
Birte Dyck
Martin Eisenacher
Barbara Sitek
Stephanie Pfaender

Frontiers in Immunology

doi 10.3389/fimmu.2025.1445403

2,097 views

Original Research

Published on 16 May 2025

Comparison of four different assays to evaluate cellular-mediated immunity against cytomegalovirus in solid organ transplantation

in Viral Immunology

Angela Casas-Parra
Hendrik Veltman
Alba Romero-Caballero
Rosana Gelpi-Remiro
Marc Boigues-Pons
Imán Allalou
Ian Linares-Pardo
Anna Vila-Santandreu
Eva Martínez-Cáceres
María Iglesias-Escudero

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567253

2,996 views

Original Research

Published on 14 May 2025

Type III interferon, age and IFNL gene single nucleotide polymorphisms determine the characteristics of H1N1 influenza infection

in Viral Immunology

Wenbo Zhu
Shao Wang
Chenchen Guan
Shuangquan Liu
Hongbo Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1592841

2,516 views
3 citations

Mini Review

Published on 14 May 2025

The intestinal interferon system and specialized enterocytes as putative drivers of HIV latency

in Viral Immunology

Rachel L. Creighton
Sean M. Hughes
Florian Hladik
Germán G. Gornalusse

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589752

3,109 views

Original Research

Published on 12 May 2025

HDL-C as a novel predictor of immune reconstitution in people living with HIV: insights from a baseline-to-dynamic change cohort study in China, 2005–2022

in Viral Immunology

Xiaorui Li
Liqin Sun
Yun He
Fang Zhao
Yinsong Luo
Chenye Liu
Yiyao Hu
Yuxin Jiang
Hongzhou Lu
Jiaye Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1520615

2,185 views
1 citation

Original Research

Published on 12 May 2025

Distinct immunity dynamics of natural killer cells in mild and moderate COVID-19 cases during the Omicron variant phase

in Viral Immunology

Yukari Nishikawa
Kosuke Yamaguchi
Ma’arif Athok Shofiudin
Momone Mimura
Miyako Takata
Shu Mihara
Takeru Kawakami
Ayumu Doi
Risa Matsuda
Hiroyuki Kato

Frontiers in Immunology

doi 10.3389/fimmu.2025.1594296

3,555 views
3 citations

Review

Published on 12 May 2025

Underestimated virus impaired cognition-more evidence and more work to do

in Viral Immunology

Maher Un Nisa Awan
Faisal Mahmood
Xiao-bin Peng
Fenshuang Zheng
Jun Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550179

2,572 views
1 citation

Original Research

Published on 09 May 2025

Virus-specific host responses and gene signatures following infection with major SARS-CoV-2 variants of concern: role of ZBP1 in viral clearance and lung inflammation

in Viral Immunology

Amany Elsharkawy
Hamid Reza Jahantigh
Anchala Guglani
Shannon Stone
Komal Arora
Mukesh Kumar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557535

5,099 views
5 citations

2,717 articles

articles

Comprehensive transcriptome assessment in PBMCs of post-COVID patients at a median follow-up of 28 months after a mild COVID infection reveals upregulation of JAK/STAT signaling and a prolonged immune response

Patrolling monocytes mediate virus neutralizing IgG effector functions: beyond neutralization capacity

Dynamic alterations of circulating lymphocytes during the trajectory of Hantaan virus-induced hemorrhagic fever with renal syndrome

Causal relationship between hepatic function indicators and thrombocytopenia risk in early-stage hepatitis B virus infection: evidence from clinical observational studies and mendelian randomization analyses

A nomogram for predicting unfavorable outcomes of antituberculosis treatment among individuals with AIDS combined with pulmonary tuberculosis in China

Mitochondrial metabolic rescue in post-COVID-19 syndrome: MR spectroscopy insights and precision nutritional therapeutics

Comparative analysis of neutrophil dynamics and disease in SARS-CoV-2 Delta and Omicron variants utilizing an in vivo feline model for COVID-19

CD4+ T cell recognition of HIV-1 alternate reading frame proteins

Multiomics analysis unveils key biomarkers during dynamic progress of IAV infection in mice

Predominant T-cell epitopes of SARS-CoV-2 restricted by multiple prevalent HLA-B and HLA-C allotypes in Northeast Asia

Neuroinflammation associated with proviral DNA persists in the brain of virally suppressed people with HIV

Distribution and potential involvement of PTEN in the innate immune response during viral infections in Cherry Valley ducks

SIV/SARS-CoV-2 coinfection in rhesus macaques impacts viral shedding, host immunity, the microbiome, and viral evolution

Metabolic reprogramming in viral infections: the interplay of glucose metabolism and immune responses

Correlation between severe acute respiratory syndrome coronavirus 2 infection and serum anti-neutrophil cytoplasmic antibody formation

Estrogen and viral infection

The protein interaction of mitochondrial transcription factors A and B2 is associated with 30-day survival in critical COVID-19

Comparison of four different assays to evaluate cellular-mediated immunity against cytomegalovirus in solid organ transplantation

Type III interferon, age and IFNL gene single nucleotide polymorphisms determine the characteristics of H1N1 influenza infection

The intestinal interferon system and specialized enterocytes as putative drivers of HIV latency

HDL-C as a novel predictor of immune reconstitution in people living with HIV: insights from a baseline-to-dynamic change cohort study in China, 2005–2022

Distinct immunity dynamics of natural killer cells in mild and moderate COVID-19 cases during the Omicron variant phase

Underestimated virus impaired cognition-more evidence and more work to do

Virus-specific host responses and gene signatures following infection with major SARS-CoV-2 variants of concern: role of ZBP1 in viral clearance and lung inflammation