Frontiers in Immunology

Original Research

Published on 05 Feb 2026

Tocilizumab combined with short-term high-dose glucocorticoids for rapid disease activity control and glucocorticoid reduction in adult-onset Still’s disease: a single-center retrospective study

Shi-Lei Zhong
Yan-Ping Lei
Li-Xuan Zhou
Ai-Xia Niu
Bo Liu
Yong-Long He
Qi-Bin Yang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1732826

450 views

Review

Published on 05 Feb 2026

Pleiotropic immunoregulation by bile acids in pathophysiology

Bo-Shen Lin
Min-Yue Yin
Si-An Xie
Peng Li
Xue Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1719092

333 views

Original Research

Published on 05 Feb 2026

Reduced retinal microvascular density in patients with mixed connective tissue disease: an exploratory pilot study on the interplay between aging, renal function, and complement system

Paola Triggianese
Eugenio Capparelli
Arianna D’Antonio
Carolina Nesi
Marco Lombardo
Barbara Kroegler
Alberto Bergamini
Raffaele Mancino
Anna Paola Mitterhofer
David Della-Morte

Frontiers in Immunology

doi 10.3389/fimmu.2026.1724780

240 views

Original Research

Published on 05 Feb 2026

Comprehensive analysis of mitochondrial unfolded protein response related genes for prognosis and therapeutic response in pancreatic cancer

Chengqing Li
Cuiling Lu
Zheng Ma
Ting Zhao
Mingming Xiao
Zhonglei Xu
Zhenxing Sun
Qihao Wu
Lei Wang
Liang Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1717925

174 views

Case Report

Published on 05 Feb 2026

Case Report: Upadacitinib for SAPHO syndrome with biologics-induced paradoxical manifestation and Hyperimmunoglobulinemia E

Yuxi Liu
Di Jin
Wen Li
Shiqi Zhang
Chen Li
Xin Li

Frontiers in Immunology

doi 10.3389/fimmu.2026.1728245

658 views

Original Research

Published on 05 Feb 2026

Memory-like CD8+ T cells lacking PD-1 adapt to persistent stimulation by reducing TCR signal transduction rather than increasing exhaustion

Mélanie Charmoy
Julia M. Maier
Tania Wyss
Vijaykumar Chennupati
Catherine Sabatel
Laurie Bonneaux
Alexandre Dumez
Romain Veber
Greta Guarda
Werner Held

Frontiers in Immunology

doi 10.3389/fimmu.2026.1743170

374 views

Review

Published on 05 Feb 2026

Advances and prospects of mucosal vaccination in the prevention and control of avian influenza

Xianfeng Hui
Xiaowei Tian
Shihuan Ding
Ge Gao
Shuoxiang Gao
Aiping Sun
Tiesuo Zhao
Hui Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1766957

225 views

Review

Published on 05 Feb 2026

Dengue–SARS-CoV-2 interactions: immune crosstalk, variant emergence, and clinical outcomes

Mariana Parra-González
Lucio Nájera-Maldonado
Esperanza Peralta-Cuevas
Ashley Gutierrez-Onofre
Luis A. Jaimes-López
Juan A. Juarez-Antonio
Nahomi Y. Degollado-Hernández
Igor Garcia-Atutxa
Francisca Villanueva-Flores

Frontiers in Immunology

doi 10.3389/fimmu.2026.1650425

2,380 views

Original Research

Published on 05 Feb 2026

NGS identifies novel HLA-DQA1 and DPB1 associations with aplastic anemia in the Kazakhstani population

Aida Turganbekova
Zhulduz Zhanzakova
Perizat Kanabekova
Dana Baimukasheva
Zhazira Saduakas
Didara Khamitova
Saniya Abdrakhmanova
Zhaksylyk Masalimov
Wassim Y. Almawi

Frontiers in Immunology

doi 10.3389/fimmu.2026.1752687

524 views

Correction

Published on 05 Feb 2026

Correction: Unlocking the adenosine receptor mechanism of the tumour immune microenvironment

Yecheng Han
Chenshuang Dong
Mingwang Hu
Xinmiao Wang
Guiling Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1786407

278 views

Mini Review

Published on 05 Feb 2026

Advances in T cell–based immunotherapy for osteosarcoma

Kun Zhang
Zheng Wang
Jiaqi He
Liuru Lu
Wenshu Wang
Aiwei Yang
Huayi Xie
Linhui Huang
Yuying Huang
Ke Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1769847

335 views

Original Research

Published on 05 Feb 2026

Comprehensive analysis of mitophagy-related genes reveals prognostic signatures in breast cancer: based on immune landscapes and treatment target predict

Hejia Zhao
Wanying Zhang
Yiheng Du
Zheng Kuang
Yilan Tan
Yanjun Chen
Yujie Ma
Fei Zou

Frontiers in Immunology

doi 10.3389/fimmu.2026.1740830

367 views

Mini Review

Published on 05 Feb 2026

Microglia heterogeneity and therapeutic strategies in Parkinson’s disease

Jing Tian
Xuehui Liu
Zhuoqun Wang
Xue Shi
Chunlei Dai
Li Yang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1739341

244 views

Correction

Published on 05 Feb 2026

Correction: Editorial: Recent trends and advancements in multispectral and hyperspectral imaging for cancer detection

I-Chen Wu
Hsiang-Chen Wang
Arvind Mukundan

Frontiers in Immunology

doi 10.3389/fimmu.2026.1798272

122 views

Original Research

Published on 05 Feb 2026

PHLDA1 is a shared diagnostic and key mediator of inflammatory fibrosis in heart and kidney

Lei Hua
Liangru Shen
Yongshou Tao
Chentong Wang
Xiaohang Shao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1765221

500 views

Original Research

Published on 05 Feb 2026

Efficacy of BCMA CAR-T cell therapy and subsequent strategies in refractory and relapsed plasma cell leukemia: a retrospective cohort study

Yuelu Guo
Lixia Ma
Fan Yang
Zhonghua Fu
Danyang Li
Rui Liu
Miaomiao Cao
Bian Wei
Yimeng Dou
Biping Deng

Frontiers in Immunology

doi 10.3389/fimmu.2026.1756209

284 views

Original Research

Published on 05 Feb 2026

Tachykinin-related peptide signalling is important for the immune response of the mealworm beetle Tenebrio molitor L.

Natalia Konopińska
Karolina Walkowiak-Nowicka
Grzegorz Nowicki
Maryam Keshavarz
Szymon Chowański
Jens Rolff
Arkadiusz Urbański

Frontiers in Immunology

doi 10.3389/fimmu.2026.1725225

474 views

Systematic Review

Published on 05 Feb 2026

Global trends of peripheral immune tolerance research: a bibliometric and visualization analysis

Shixiao Kong
Chen Lin
Yuting Shen
Jun Chen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1730575

715 views

Original Research

Published on 05 Feb 2026

Possible role of pre-vaccination T-lymphocyte subpopulations in the antibody response to COVID-19 vaccines in children undergoing chemotherapy

Csaba Péterfia
Zsolt I. Komlósi
Zoltán Pós
Nikolett Lupsa
Nóra Fekete
Katalin Böröcz
Timea Dergez
Evelin A. Leibinger
Noémi Benedek
Ágnes Vojcek

Frontiers in Immunology

doi 10.3389/fimmu.2026.1728845

336 views

Original Research

Published on 05 Feb 2026

Recombinant ROP8 antigen: diagnostics, immunogenicity, and therapeutic targeting in toxoplasmosis

Maciej Chyb
Adrian Bekier
Malwina Kawka
Bartłomiej Ferra
Bożena Dziadek
Sylwia Michlewska
Katarzyna Dzitko
Nazar Trotsko
Justyna Gatkowska

Frontiers in Immunology

doi 10.3389/fimmu.2026.1768856

348 views

Review

Published on 05 Feb 2026

Utility of contrast-enhanced ultrasound for assessing disease activity in takayasu arteritis with carotid artery involvement: a scoping review

Carina Soto-Fajardo
Rosa-Elena Cervantes-Ramírez
Carlos-Vidal Montiel-Castañeda
Ada-Rocío Morales-Meza
Daniela-Isabel Rojas-Abarca
Fabiola-Bugambilia Sánchez-Zamudio
Hugo Sandoval
Carlos Pineda

Frontiers in Immunology

doi 10.3389/fimmu.2026.1767181

234 views

Case Report

Published on 05 Feb 2026

Migratory vasodilatation of cerebral arteries in MELAS episodes: a case report and literature review

Ying Luo
Quanhong Chu
Taochun Yu
Xiaoqing Lu
Yanmei Wang
Jie Li
Lingfeng Wu
Yaoyao Shen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1706012

174 views

Original Research

Accepted on 04 Feb 2026

Impact of testosterone-based gender affirming hormone therapy on toll-like receptor transcript levels and peripheral blood leukocyte counts in transmasculine individuals

Hüseyin Cihan
Özge Güngör
Gökcen Ünal Kocabas
Esma Pehlivan Köroglu
Kübra Gülpinar
Erhan Pariltay
Fatma Ömür Ardeniz
Guy T’Sjoen
Jonatan Leffler
Bettina Winzeler

Frontiers in Immunology

386 views

49,695 Publications

volumes

Volume 17 - 2026

Tocilizumab combined with short-term high-dose glucocorticoids for rapid disease activity control and glucocorticoid reduction in adult-onset Still’s disease: a single-center retrospective study

Pleiotropic immunoregulation by bile acids in pathophysiology

Reduced retinal microvascular density in patients with mixed connective tissue disease: an exploratory pilot study on the interplay between aging, renal function, and complement system

Comprehensive analysis of mitochondrial unfolded protein response related genes for prognosis and therapeutic response in pancreatic cancer

Case Report: Upadacitinib for SAPHO syndrome with biologics-induced paradoxical manifestation and Hyperimmunoglobulinemia E

Memory-like CD8+ T cells lacking PD-1 adapt to persistent stimulation by reducing TCR signal transduction rather than increasing exhaustion

Advances and prospects of mucosal vaccination in the prevention and control of avian influenza

Dengue–SARS-CoV-2 interactions: immune crosstalk, variant emergence, and clinical outcomes

NGS identifies novel HLA-DQA1 and DPB1 associations with aplastic anemia in the Kazakhstani population

Correction: Unlocking the adenosine receptor mechanism of the tumour immune microenvironment

Advances in T cell–based immunotherapy for osteosarcoma

Comprehensive analysis of mitophagy-related genes reveals prognostic signatures in breast cancer: based on immune landscapes and treatment target predict

Microglia heterogeneity and therapeutic strategies in Parkinson’s disease

Correction: Editorial: Recent trends and advancements in multispectral and hyperspectral imaging for cancer detection

PHLDA1 is a shared diagnostic and key mediator of inflammatory fibrosis in heart and kidney

Efficacy of BCMA CAR-T cell therapy and subsequent strategies in refractory and relapsed plasma cell leukemia: a retrospective cohort study

Tachykinin-related peptide signalling is important for the immune response of the mealworm beetle Tenebrio molitor L.

Global trends of peripheral immune tolerance research: a bibliometric and visualization analysis

Possible role of pre-vaccination T-lymphocyte subpopulations in the antibody response to COVID-19 vaccines in children undergoing chemotherapy

Recombinant ROP8 antigen: diagnostics, immunogenicity, and therapeutic targeting in toxoplasmosis

Utility of contrast-enhanced ultrasound for assessing disease activity in takayasu arteritis with carotid artery involvement: a scoping review

Migratory vasodilatation of cerebral arteries in MELAS episodes: a case report and literature review

Impact of testosterone-based gender affirming hormone therapy on toll-like receptor transcript levels and peripheral blood leukocyte counts in transmasculine individuals

Volume 16 - 2025

Immune activation and microenvironmental crosstalk in hairy cell leukemia