Frontiers in Immunology

Original Research

Published on 28 Jan 2025

Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation

Lei Sun
Jinhao Zhang
Zhikai Xiahou
Zhenzhen Zhao
Yanchen Liang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1506225

7,752 views
5 citations

Original Research

Published on 28 Jan 2025

Recombinant SpTransformer proteins bind to specific sites on sea urchin phagocytes and modulate SpTransformer gene expression and immune responsiveness

Ryley S. Crow
Leon Grayfer
L. Courtney Smith

Frontiers in Immunology

doi 10.3389/fimmu.2024.1496832

3,549 views
3 citations

Original Research

Published on 28 Jan 2025

Designing a broad-spectrum multi-epitope subunit vaccine against leptospirosis using immunoinformatics and structural approaches

Guneswar Sethi
Young Kyu Kim
Su-Cheol Han
Jeong Ho Hwang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1503853

5,864 views
7 citations

Case Report

Published on 28 Jan 2025

Case report: Advanced age at transplantation and pre-emptive treatment with dupilumab in DOCK8 deficiency

Sophia Trombello
Andrea Jarisch
Andre Willasch
Eva Rettinger
Julia Fekadu-Siebald
Dirk Holzinger
Roland Adelmann
Peter Bader
Shahrzad Bakhtiar

Frontiers in Immunology

doi 10.3389/fimmu.2024.1507494

3,238 views
1 citation

Hypothesis and Theory

Published on 28 Jan 2025

Why is it so difficult to understand why we don’t understand human systemic lupus erythematosus? Contemplating facts, conflicts, and impact of “the causality cascade paradigm”

Ole Petter Rekvig

Frontiers in Immunology

doi 10.3389/fimmu.2024.1507792

4,267 views
2 citations

Brief Research Report

Published on 28 Jan 2025

Serum and tear autoantibodies from NOD and NOR mice as potential diagnostic indicators of local and systemic inflammation in Sjögren’s disease

Shruti Singh Kakan
Sara Abdelhamid
Yaping Ju
J. Andrew MacKay
Maria C. Edman
Indu Raman
Chengsong Zhu
Prithvi Raj
Sarah F. Hamm-Alvarez

Frontiers in Immunology

doi 10.3389/fimmu.2024.1516330

4,674 views
1 citation

Original Research

Published on 27 Jan 2025

Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning

Shuxian Pan
Zibing Wang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1516524

4,179 views
6 citations

Original Research

Published on 27 Jan 2025

Proteomic and serologic assessments of responses to mRNA-1273 and BNT162b2 vaccines in human recipient sera

Thomas E. Hickey
Uma Mudunuri
Heidi A. Hempel
Troy J. Kemp
Nancy V. Roche
Keyur Talsania
Brian A. Sellers
James M. Cherry
Ligia A. Pinto

Frontiers in Immunology

doi 10.3389/fimmu.2024.1502458

9,527 views
1 citation

Hypothesis and Theory

Published on 27 Jan 2025

The liver’s dilemma: sensing real danger in a sea of PAMPs: the (arterial) sinusoidal segment theory

Andrea Henriques-Pons
Natália Vacani-Martins
Carina de Lima Pereira dos Santos
Marcelo Meuser-Batista

Frontiers in Immunology

doi 10.3389/fimmu.2024.1503063

4,228 views
3 citations

Original Research

Published on 27 Jan 2025

Plasma IL-17A is increased in patients with critical MIS-C and associated to in-hospital mortality

Emmerson C. F. de Farias
Luciana M. P. P. do Nascimento
Manoel J. C. Pavão Junior
Dalila C. A. Pavão
Ana P. S. Pinheiro
Andreza H. O. Pinheiro
Marília C. B. Alves
Kíssila M. M. M. Ferraro
Larisse F. Q. Aires
Luana G. Dias

Frontiers in Immunology

doi 10.3389/fimmu.2024.1485009

2,882 views
1 citation

Correction

Published on 24 Jan 2025

Corrigendum: Identifying risk factors for secondary infection post-SARS-COV-2 infection in patients with severe and critical COVID-19

Mingquan Guo
Menglu Gao
Jing Gao
Tengfei Zhang
Xin Jin
Jian Fan
Qianying Wang
Xin Li
Jian Chen
Zhaoqin Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1548101

1,558 views

Original Research

Published on 24 Jan 2025

Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance

Santiago Rodríguez de Córdoba
Andrea Reparaz
Daniel Sanchez
Sheila Pinto
Lucia Juana Lopez
Héctor Martin Merinero
Iria Calvete
Julian Perez-Perez
Sydney S. Jellison
Yuzhou Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1527016

3,448 views
5 citations

Original Research

Published on 24 Jan 2025

Single-cell sequencing uncovers the mechanistic role of DAPK1 in glioma and its diagnostic and prognostic implications

Tian-Hang Yu
Yan-Yu Ding
Si-Guo Zhao
Jie-Hui Zhao
Yu Gu
Dong-Hui Chen
Fang Zhang
Wen-Ming Hong

Frontiers in Immunology

doi 10.3389/fimmu.2024.1463747

5,278 views
2 citations

Original Research

Published on 24 Jan 2025

MUC2 expression modulates immune infiltration in colorectal cancer

Christophe M. Raynaud
Ayesha Jabeen
Eiman I. Ahmed
Satanay Hubrack
Apryl Sanchez
Shimaa Sherif
Ahmad A. Al-Shaibi
Bernice Lo
Jessica Roelands
Davide Bedognetti

Frontiers in Immunology

doi 10.3389/fimmu.2024.1500374

5,999 views
4 citations

Original Research

Published on 24 Jan 2025

Pan-cancer and experimental analyses reveal the immunotherapeutic significance of CST2 and its association with stomach adenocarcinoma proliferation and metastasis

Dan Huang
Jing Li
Zhijun He
Wenjing Liang
Likun Zhong
Jun Huang
Yinteng Wu
Shijian Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2024.1466806

3,921 views
4 citations

Original Research

Published on 24 Jan 2025

Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning

Zuhui Pu
Tony Bowei Wang
Ying Lu
Zijing Wu
Yuxian Chen
Ziqi Luo
Xinyu Wang
Lisha Mou

Frontiers in Immunology

doi 10.3389/fimmu.2024.1479166

4,524 views
2 citations

Mini Review

Published on 24 Jan 2025

Thymus ad astra, or spaceflight-induced thymic involution

Wataru Muramatsu
Maria Maryanovich
Taishin Akiyama
George S. Karagiannis

Frontiers in Immunology

doi 10.3389/fimmu.2024.1534444

6,267 views
3 citations

Original Research

Published on 24 Jan 2025

Clinical assessment and transcriptome analysis of host immune responses in a vaccination-challenge study using a glycoprotein G deletion mutant vaccine strain of infectious laryngotracheitis virus

Gayathri Gopakumar
Mauricio J. C. Coppo
Andrés Diaz-Méndez
Carol A. Hartley
Joanne M. Devlin

Frontiers in Immunology

doi 10.3389/fimmu.2024.1458218

3,808 views
1 citation

Review

Published on 23 Jan 2025

Immunotherapy of osteosarcoma based on immune microenvironment modulation

Heping Lian
Jiakui Zhang
Shuna Hou
Shuang Ma
Jiachen Yu
Wei Zhao
Duoyi Zhao
Zhiyu Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1498060

6,412 views
15 citations

Clinical Trial

Published on 23 Jan 2025

Single-cell RNA sequencing reveals the dysfunctional characteristics of PBMCs in patients with type 2 diabetes mellitus

Jindong Zhao
Zhaohui Fang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1501660

7,317 views
6 citations

Original Research

Published on 23 Jan 2025

Colorimetric aptasensor coupled with a deep-learning-powered smartphone app for programmed death ligand-1 expressing extracellular vesicles

Adeel Khan
Haroon Khan
Nongyue He
Zhiyang Li
Heba Khalil Alyahya
Yousef A. Bin Jardan

Frontiers in Immunology

doi 10.3389/fimmu.2024.1479403

3,492 views
4 citations

Case Report

Published on 23 Jan 2025

Case report: Toxic epidermal necrolysis as a unique presentation of acute graft versus host disease in a pediatric patient

Elizabeth Marlowe
Rachel Palmer
April L. Rahrig
Devin Dinora
Jessica Harrison
Jodi Skiles
Mahvish Q. Rahim

Frontiers in Immunology

doi 10.3389/fimmu.2024.1452245

3,313 views
4 citations

Original Research

Published on 23 Jan 2025

Feature selection enhances peptide binding predictions for TCR-specific interactions

Hamid Teimouri
Zahra S. Ghoreyshi
Anatoly B. Kolomeisky
Jason T. George

Frontiers in Immunology

doi 10.3389/fimmu.2024.1510435

4,342 views
5 citations

Systematic Review

Published on 23 Jan 2025

Efficacy and safety of PD-1 inhibitors as second-line treatment for advanced squamous esophageal cancer: a systematic review and network meta-analysis with a focus on PD-L1 expression levels

Fei Yang
Min Dan
Jindan Shi
Ling Fan
Haoluo Zhang
Tiantian Jian
Kelu Lei
Yue Wang
Juan Xin
Zhigang Yu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1510145

6,072 views
5 citations

5,525 Publications

volumes

Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation

Recombinant SpTransformer proteins bind to specific sites on sea urchin phagocytes and modulate SpTransformer gene expression and immune responsiveness

Designing a broad-spectrum multi-epitope subunit vaccine against leptospirosis using immunoinformatics and structural approaches

Case report: Advanced age at transplantation and pre-emptive treatment with dupilumab in DOCK8 deficiency

Why is it so difficult to understand why we don’t understand human systemic lupus erythematosus? Contemplating facts, conflicts, and impact of “the causality cascade paradigm”

Serum and tear autoantibodies from NOD and NOR mice as potential diagnostic indicators of local and systemic inflammation in Sjögren’s disease

Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning

Proteomic and serologic assessments of responses to mRNA-1273 and BNT162b2 vaccines in human recipient sera

The liver’s dilemma: sensing real danger in a sea of PAMPs: the (arterial) sinusoidal segment theory

Plasma IL-17A is increased in patients with critical MIS-C and associated to in-hospital mortality

Corrigendum: Identifying risk factors for secondary infection post-SARS-COV-2 infection in patients with severe and critical COVID-19

Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance

Single-cell sequencing uncovers the mechanistic role of DAPK1 in glioma and its diagnostic and prognostic implications

MUC2 expression modulates immune infiltration in colorectal cancer

Pan-cancer and experimental analyses reveal the immunotherapeutic significance of CST2 and its association with stomach adenocarcinoma proliferation and metastasis

Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning

Thymus ad astra, or spaceflight-induced thymic involution

Clinical assessment and transcriptome analysis of host immune responses in a vaccination-challenge study using a glycoprotein G deletion mutant vaccine strain of infectious laryngotracheitis virus

Immunotherapy of osteosarcoma based on immune microenvironment modulation

Single-cell RNA sequencing reveals the dysfunctional characteristics of PBMCs in patients with type 2 diabetes mellitus

Colorimetric aptasensor coupled with a deep-learning-powered smartphone app for programmed death ligand-1 expressing extracellular vesicles

Case report: Toxic epidermal necrolysis as a unique presentation of acute graft versus host disease in a pediatric patient

Feature selection enhances peptide binding predictions for TCR-specific interactions

Efficacy and safety of PD-1 inhibitors as second-line treatment for advanced squamous esophageal cancer: a systematic review and network meta-analysis with a focus on PD-L1 expression levels