Frontiers in Immunology

Original Research

Accepted on 19 Feb 2026

Risk Factors and Immune Landscape of Early Local Tumor Progression after Microwave Ablation for Lung Cancer: A Retrospective Nested Case-control Study

Nan Wang
Jingwen Xu
Ji Ma
Siyi Niu
Xiuhong Ren
Qi Xie
Zhigang Wei
Xin Ye

Frontiers in Immunology

Original Research

Published on 19 Feb 2026

TIGIT impairs NK cell antifibrotic activity through the IFNγ–IFI30 axis in schistosomiasis-induced liver fibrosis

Hui Peng
Jing Zhang
Xiaocheng Zhang
Hao Zhou
Lijun Cui
Fangfang Xu
Tingting Jiang
Jianhai Yin
Yuan Hu
Yujuan Shen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1766930

Original Research

Published on 19 Feb 2026

MERS-CoV and SARS-CoV-1 proteins inhibit the IFN-α JAK/STAT pathway of epithelial cells, via IFN-λ-induced USP18

Yamei Zhang
Nigel J. Stevenson

Frontiers in Immunology

doi 10.3389/fimmu.2026.1739662

209 views

Original Research

Published on 19 Feb 2026

Inferring tumor immune microenvironment -related risk states from pretreatment H&E pathomics and clinical biomarkers to predict checkpoint inhibitor pneumonitis in advanced NSCLC: a multicenter multimodal study

Lei Yuan
Qi Wang
Fei Sun
Wenlong Yang
Jie Lei
Juan Liu
Yiwei Fan
Yibo Shan
Yi Lu
Yaojing Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1792179

152 views

Review

Published on 19 Feb 2026

Role of mucosal chemokines in the development of tissue-resident CD4+ and CD8+ TRM cells to fend off herpes simplex infections

Yassir Lekbach
Aziz A. Chentoufi
Swayam Prakash
Sweta Karan
Afshana Quadiri
Kathy K. Hormi-Carver
Joshua Christian Dorotta
Lbachir BenMohamed

Frontiers in Immunology

doi 10.3389/fimmu.2026.1661640

198 views

Original Research

Published on 19 Feb 2026

The hidden link between iron deficiency and celiac disease: a clinical perspective

Laura Tarancon-Diez
Guillermo Perez-Cabeza
Pilar Sanchez-Mingo
Pedro Crespo-de la Rosa
Rita-Maria Garcia
Marianela Iriarte-Gahete
Yolanda M. Pacheco
Manuel Leal

Frontiers in Immunology

doi 10.3389/fimmu.2026.1744005

382 views

Original Research

Published on 19 Feb 2026

Integrating pleural PD-1+CD8+ T cell as a complement variable into LENT score to assess patients with lung adenocarcinoma complicated with MPE

Weizhen Jiang
Leilei Lv
Yaoxin Zhang
Qiuxia Qu
Cheng Chen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1630590

122 views

Review

Published on 19 Feb 2026

Exosomal non-coding RNAs in autoimmune diseases: molecular mechanisms and potential applications

Yunbing Wu
Xia Li
Yue Jin
Fei Mao
Lu Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1753611

108 views

Original Research

Published on 19 Feb 2026

Integrating network pharmacology, microbiomics, and metabolomics to uncover the therapeutic effect of Liubao tea on osteoarthritis

Guoping Le
Riyou Wen
Zhifa Huang
Huaixi Fang
Jianwei Zheng
Yong Wang
Hanwen Luo

Frontiers in Immunology

doi 10.3389/fimmu.2026.1746350

189 views

Original Research

Published on 19 Feb 2026

Co-delivery of endometrial mesenchymal stem cells and macrophages with an electrospun patch suppresses endometrial fibrosis via IL-10 related signaling

Jiangru An
Shuhong Li
Tianyi Ma
Yonghua Chen
J. Paul Santerre
Wenshuang Wang
Peng Ma
Xiaoqing Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1750456

Systematic Review

Published on 19 Feb 2026

Radiotherapy plus immune checkpoint inhibitors versus immune checkpoint inhibitors alone for non-small cell lung cancer with bone metastases: a systematic review and meta-analysis of comparative cohort studies

Yingding Ruan
Wenjun Cao
Chuan Long
Siyu Guo
Jianwei Han
Zhendong Chen
Ting Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1773998

Original Research

Published on 19 Feb 2026

400 AU/mL IgG protective threshold against SARS-CoV-2 XBB reinfection in Chinese inactivated vaccine recipients: implications for booster vaccination

Zhiying Yin
Mengcheng Yin
Fei Zhao
Canya Fu
Wenjie Xu
Quanjun Fang
Xiaoying Gong
Shuangqing Wang
Canjie Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2026.1768679

Editorial

Published on 19 Feb 2026

Editorial: Unlocking the microbial code: potential role in sarcoidosis pathogenesis and treatment

Claudio Tana
Nicol Bernardinello
Paolo Spagnolo

Frontiers in Immunology

doi 10.3389/fimmu.2026.1796347

Systematic Review

Published on 19 Feb 2026

Impact of creatine supplementation on inflammation: evidence from a systematic review and meta-analysis of randomized double-blind placebo trials

Kell Mazzini Ribeiro de Camargo
Alejandro Bruna-Mejías
Juan José Valenzuela-Fuenzalida
Luana A. Gonzaga
Sandra Maria Barbalho
Alexandre L. Barroca
Andrey A. Porto
Rodrigo D. Raimundo
Luiz Carlos de Abreu
Vitor E. Valenti

Frontiers in Immunology

doi 10.3389/fimmu.2026.1743603

1,436 views

Brief Research Report

Published on 19 Feb 2026

Immunogenic insights and experimental validation of a multiepitope vaccine construct against Streptococcus pneumoniae

Yogeshwar Devarakonda
M. V. N. Janardhan Reddy
Arunima Binu
Kirtimaan Syal

Frontiers in Immunology

doi 10.3389/fimmu.2026.1781081

136 views

Brief Research Report

Published on 19 Feb 2026

Flat dose intravenous immunoglobulin primary infection prophylaxis in multiple myeloma patients on BCMA and GPRC5D bispecific antibody therapy: the Vanderbilt experience

Naimisha Marneni
Spencer Lessans
Bhagirathbhai Dholaria
Salyka Sengsayadeth
Eden A. Biltibo
Vivek Patel
Shakthi Bhaskar
Reena Jayani
Sanjay Mohan
Ashwin Kishtagari

Frontiers in Immunology

doi 10.3389/fimmu.2026.1721820

296 views

Original Research

Published on 19 Feb 2026

Development and validation of a potency assay matrix for optimized and consistent manufacture of clinical mesenchymal stem/stromal cells

Patrick Niekamp
Dongsheng Gu
Jie Jiang
Erik J. Woods
Brian H. Johnstone

Frontiers in Immunology

doi 10.3389/fimmu.2026.1725191

100 views

Case Report

Published on 19 Feb 2026

Case Report: Interleukin-23 blockade achieves sustained remission in Niemann–Pick type C-associated Crohn’s disease refractory to anti-tumor necrosis factor therapy

Toshihiko Kakiuchi
Satomi Shimada
Yumeng Zhang
Miri Nomura
Masato Yoshiura

Frontiers in Immunology

doi 10.3389/fimmu.2026.1766960

102 views

Review

Published on 19 Feb 2026

Neoadjuvant chemotherapy-induced immune remodeling in ovarian cancer: implications for TIL dynamics and combination immunotherapy

Wanting Zhu
Jiajia Li
Yihua Sun
Qianhan Lin
Yating Sun
Mengyang Xue
Chang Zheng
Xiuling Zhi
Liangqing Yao
Mo Chen

Frontiers in Immunology

doi 10.3389/fimmu.2026.1757366

221 views

Review

Published on 19 Feb 2026

Ferroptosis as a therapeutic nexus: traditional Chinese medicine interventions in rheumatoid arthritis

Ruibin Yang
Ziwei Yang
Zhuan Feng
Yaxin Ding
Jiali Yang
Yinuo Zhang
Zhi-Nan Chen
Fei Huo
Jiao Wu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1768013

264 views

Hypothesis and Theory

Accepted on 18 Feb 2026

The Bio-Intelligence Circuit: A Hypothesis-Generating Systems Framework Linking Mitochondrial Stress, Innate immune Signaling, and Autonomic Regulation in Chronic Inflammation

Parthiban Subramanian
Vinodhini Parthiban

Frontiers in Immunology

Mini Review

Accepted on 18 Feb 2026

Immunomodulation by Glycosylation: Bridging Glycobiology to Adaptive Immunity and Therapeutic Innovation

shengwen ding
Han Wang
Zhaoxin Han
Senlian Hong

Frontiers in Immunology

Review

Accepted on 18 Feb 2026

Cytokine-inducible SH2 domain containing protein (CISH): a versatile negative regulator of cytokine receptor signaling

Wasan Naser
Alister Curtis Ward

Frontiers in Immunology

Case Report

Accepted on 18 Feb 2026

Dual response to efgartigimod in myasthenia gravis and comorbid autoimmune disorders: a case series

Yunjia Li
Yingying Yang
Ying Zhu
Ruixia Zhu

Frontiers in Immunology

1,244 Publications

volumes

Risk Factors and Immune Landscape of Early Local Tumor Progression after Microwave Ablation for Lung Cancer: A Retrospective Nested Case-control Study

TIGIT impairs NK cell antifibrotic activity through the IFNγ–IFI30 axis in schistosomiasis-induced liver fibrosis

MERS-CoV and SARS-CoV-1 proteins inhibit the IFN-α JAK/STAT pathway of epithelial cells, via IFN-λ-induced USP18

Inferring tumor immune microenvironment -related risk states from pretreatment H&E pathomics and clinical biomarkers to predict checkpoint inhibitor pneumonitis in advanced NSCLC: a multicenter multimodal study

Role of mucosal chemokines in the development of tissue-resident CD4+ and CD8+ TRM cells to fend off herpes simplex infections

The hidden link between iron deficiency and celiac disease: a clinical perspective

Integrating pleural PD-1+CD8+ T cell as a complement variable into LENT score to assess patients with lung adenocarcinoma complicated with MPE

Exosomal non-coding RNAs in autoimmune diseases: molecular mechanisms and potential applications

Integrating network pharmacology, microbiomics, and metabolomics to uncover the therapeutic effect of Liubao tea on osteoarthritis

Co-delivery of endometrial mesenchymal stem cells and macrophages with an electrospun patch suppresses endometrial fibrosis via IL-10 related signaling

Radiotherapy plus immune checkpoint inhibitors versus immune checkpoint inhibitors alone for non-small cell lung cancer with bone metastases: a systematic review and meta-analysis of comparative cohort studies

400 AU/mL IgG protective threshold against SARS-CoV-2 XBB reinfection in Chinese inactivated vaccine recipients: implications for booster vaccination

Editorial: Unlocking the microbial code: potential role in sarcoidosis pathogenesis and treatment

Impact of creatine supplementation on inflammation: evidence from a systematic review and meta-analysis of randomized double-blind placebo trials

Immunogenic insights and experimental validation of a multiepitope vaccine construct against Streptococcus pneumoniae

Flat dose intravenous immunoglobulin primary infection prophylaxis in multiple myeloma patients on BCMA and GPRC5D bispecific antibody therapy: the Vanderbilt experience

Development and validation of a potency assay matrix for optimized and consistent manufacture of clinical mesenchymal stem/stromal cells

Case Report: Interleukin-23 blockade achieves sustained remission in Niemann–Pick type C-associated Crohn’s disease refractory to anti-tumor necrosis factor therapy

Neoadjuvant chemotherapy-induced immune remodeling in ovarian cancer: implications for TIL dynamics and combination immunotherapy

Ferroptosis as a therapeutic nexus: traditional Chinese medicine interventions in rheumatoid arthritis

The Bio-Intelligence Circuit: A Hypothesis-Generating Systems Framework Linking Mitochondrial Stress, Innate immune Signaling, and Autonomic Regulation in Chronic Inflammation

Immunomodulation by Glycosylation: Bridging Glycobiology to Adaptive Immunity and Therapeutic Innovation

Cytokine-inducible SH2 domain containing protein (CISH): a versatile negative regulator of cytokine receptor signaling

Dual response to efgartigimod in myasthenia gravis and comorbid autoimmune disorders: a case series