Frontiers in Medical Technology

Original Research

Published on 04 Apr 2022

Effect of Patent Expiry on the Performance of Innovator Multinational Pharmaceutical Companies in a Low Middle Income Country

in Pharmaceutical Innovation

Farrukh Khalil
Joseph Odhiambo Onyango

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.783460

13,945 views
4 citations

Technology and Code

Published on 01 Apr 2022

Crossing Total Occlusions Using a Hydraulic Pressure Wave: Development of the Wave Catheter

in Cardiovascular Medtech

Aimee Sakes
Menno Lageweg
Remi I. B. van Starkenburg
Saurabh Sontakke
Jo W. Spronck

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.851927

7,552 views
3 citations

Original Research

Published on 28 Mar 2022

Identification of 1, 2, 4-Triazine and Its Derivatives Against Lanosterol 14-Demethylase (CYP51) Property of Candida albicans: Influence on the Development of New Antifungal Therapeutic Strategies

in Pharmaceutical Innovation

Abhishek Kumar Verma
Aarfah Majid
Md. Shahadat Hossain
SK. Faisal Ahmed
Mohammad Ashid
Ali Asger Bhojiya
Sudhir K. Upadhyay
Naveen Kumar Vishvakarma
Mudassir Alam

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.845322

6,697 views
17 citations

Review

Published on 28 Mar 2022

Optimization of Anti-SARS-CoV-2 Neutralizing Antibody Therapies: Roadmap to Improve Clinical Effectiveness and Implementation

in Regulatory Affairs

Karlijn van der Straten
Marit J. van Gils
Steven W. de Taeye
Godelieve J. de Bree

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.867982

7,103 views
15 citations

Original Research

Published on 21 Mar 2022

A Novel Laser Energy Ablation Catheter for Endocardial Cavo-Tricuspid Isthmus Ablation and Epicardial Ventricular Lesion Formation: An in vivo Proof-of-Concept Study

in Cardiovascular Medtech

Dennis Krist
Dominik Linz
Ulrich Schotten
Stef Zeemering
Dwayne Leenen

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.834856

3,269 views
3 citations

Original Research

Published on 17 Mar 2022

Improvement of Mesenchymal Stromal Cell Proliferation and Differentiation via Decellularized Extracellular Matrix on Substrates With a Range of Surface Chemistries

in Regenerative Technologies

Michael C. Yang
Andrea J. O'Connor
Bill Kalionis
Daniel E. Heath

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.834123

4,394 views
10 citations

Original Research

Published on 11 Mar 2022

Exploring Unsupervised Machine Learning Classification Methods for Physiological Stress Detection

in Diagnostic and Therapeutic Devices

Talha Iqbal
Adnan Elahi
William Wijns
Atif Shahzad

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.782756

16,050 views
40 citations

Editorial

Published on 10 Mar 2022

Editorial: Verification and Validation of in silico Models for Biomedical Implantable Devices

in Cardiovascular Medtech

Lorenza Petrini
Giancarlo Pennati
Dimitrios I. Fotiadis

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.856067

3,087 views
3 citations

Mini Review

Published on 09 Mar 2022

Application of Transcriptomics for Predicting Protein Interaction Networks, Drug Targets and Drug Candidates

in Medtech Data Analytics

Dulshani Kankanige
Liwan Liyanage
Michael D. O'Connor

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.693148

4,881 views
4 citations

Original Research

Published on 08 Mar 2022

Physician Experience in Technical Success of Achieving NPVR ≥ 80% of High-Intensity Focused Ultrasound Ablation for Uterine Fibroids: A Multicenter Study

in Medtech Data Analytics

Xue Gong
Xinyue Zhang
Dang Liu
Chao Yang
Rong Zhang
Zhibo Xiao
Wenzhi Chen
Jinyun Chen

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.790956

3,085 views
8 citations

Perspective

Published on 24 Feb 2022

Where National Medicines Policies Have Taken Us With Patient Involvement and Health Technology Assessment in Africa

in Regulatory Affairs

Kawaldip Sehmi
Janet L. Wale

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.810456

8,693 views
5 citations

Perspective

Published on 24 Feb 2022

Solving the Evidence Interpretability Crisis in Health Technology Assessment: A Role for Mechanistic Models?

in Regulatory Affairs

Eulalie Courcelles
Jean-Pierre Boissel
Jacques Massol
Ingrid Klingmann
Riad Kahoul
Marc Hommel
Emmanuel Pham
Alexander Kulesza

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.810315

4,189 views
8 citations

Correction

Published on 24 Feb 2022

Corrigendum: A Psychometric Platform to Collect Somatosensory Sensations for Neuroprosthetic Use

in Medtech Data Analytics

Giacomo Valle
Francesco Iberite
Ivo Strauss
Edoardo D'Anna
Giuseppe Granata
Riccardo Di Iorio
Thomas Stieglitz
Stanisa Raspopovic
Francesco M. Petrini
Paolo M. Rossini

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.866538

1,622 views

Review

Published on 22 Feb 2022

Electroactive Scaffolds to Improve Neural Stem Cell Therapy for Spinal Cord Injury

in Regenerative Technologies

Anthea R. Mutepfa
John G. Hardy
Christopher F. Adams

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.693438

7,602 views
25 citations

Original Research

Published on 17 Feb 2022

Additive Manufacturing of a Miniature Functional Trocar for Eye Surgery

in Diagnostic and Therapeutic Devices

Kirsten Lussenburg
Marta Scali
Aimée Sakes
Paul Breedveld

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.842958

5,263 views
5 citations

Original Research

Published on 16 Feb 2022

Mechanism-Driven Modeling to Aid Non-invasive Monitoring of Cardiac Function via Ballistocardiography

in Diagnostic and Therapeutic Devices

Mohamed Zaid
Lorenzo Sala
Jan R. Ivey
Darla L. Tharp
Christina M. Mueller
Pamela K. Thorne
Shannon C. Kelly
Kleiton Augusto Santos Silva
Amira R. Amin
Pilar Ruiz-Lozano

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.788264

7,321 views
10 citations

Editorial

Published on 04 Feb 2022

Editorial: Computational Approaches to Foster Innovation in the Treatment and Diagnosis of Infectious Diseases

in Pharmaceutical Innovation

Diana Lousa
Cláudio M. Soares
Fernando L. Barroso da Silva

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.841088

1,599 views
4 citations

Original Research

Published on 01 Feb 2022

Assessment of Smartphone-Based Spiral Tracing in Multiple Sclerosis Reveals Intra-Individual Reproducibility as a Major Determinant of the Clinical Utility of the Digital Test

in Diagnostic and Therapeutic Devices

Komi S. Messan
Linh Pham
Thomas Harris
Yujin Kim
Vanessa Morgan
Peter Kosa
Bibiana Bielekova

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.714682

3,877 views
8 citations

Original Research

Published on 26 Jan 2022

Reconstructing the Effectiveness of Policy Measures to Avoid Next-Wave COVID-19 Infections and Deaths Using a Dynamic Simulation Model: Implications for Health Technology Assessment

in Regulatory Affairs

Arnold Hagens
Kathya Cordova-Pozo
Maarten Postma
Jan Wilschut
Lorenzo Zino
Jurjen van der Schans

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.666581

5,760 views
5 citations

Review

Published on 25 Jan 2022

Drug Delivery Systems for the Oral Administration of Antimicrobial Peptides: Promising Tools to Treat Infectious Diseases

in Nano-Based Drug Delivery

Caroline Deshayes
Md. Nasir Arafath
Véronique Apaire-Marchais
Emilie Roger

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.778645

13,118 views
53 citations

Perspective

Published on 25 Jan 2022

Can We Afford to Exclude Patients Throughout Health Technology Assessment?

in Regulatory Affairs

Janet L. Wale
David Chandler
Deborah Collyar
Dominique Hamerlijnck
Roberto Saldana
Zack Pemberton-Whitely

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.796344

6,551 views
9 citations

Original Research

Published on 21 Jan 2022

Patient Involvement in the Health Technology Assessment Process in Taiwan

in Regulatory Affairs

Kuei An Chen
Li Ying Huang
Churn Shiouh Gau

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.732160

6,065 views
5 citations

Editorial

Published on 14 Jan 2022

Editorial: Data-Enabled Intelligence for Medical Technology Innovation, Volume I

in Medtech Data Analytics

Nianyin Zeng
Kathy Clawson
Yonghong Peng

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.841150

1,911 views
1 citation

Original Research

Published on 05 Jan 2022

In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors

in Regulatory Affairs

Gabriel Rojas-Jiménez
Daniela Solano
Álvaro Segura
Andrés Sánchez
Stephanie Chaves-Araya
María Herrera
Mariángela Vargas
Maykel Cerdas
Gerardo Calvo
Jonathan Alfaro

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.772275

4,420 views
7 citations

418 articles

articles

Effect of Patent Expiry on the Performance of Innovator Multinational Pharmaceutical Companies in a Low Middle Income Country

Crossing Total Occlusions Using a Hydraulic Pressure Wave: Development of the Wave Catheter

Identification of 1, 2, 4-Triazine and Its Derivatives Against Lanosterol 14-Demethylase (CYP51) Property of Candida albicans: Influence on the Development of New Antifungal Therapeutic Strategies

Optimization of Anti-SARS-CoV-2 Neutralizing Antibody Therapies: Roadmap to Improve Clinical Effectiveness and Implementation

A Novel Laser Energy Ablation Catheter for Endocardial Cavo-Tricuspid Isthmus Ablation and Epicardial Ventricular Lesion Formation: An in vivo Proof-of-Concept Study

Improvement of Mesenchymal Stromal Cell Proliferation and Differentiation via Decellularized Extracellular Matrix on Substrates With a Range of Surface Chemistries

Exploring Unsupervised Machine Learning Classification Methods for Physiological Stress Detection

Editorial: Verification and Validation of in silico Models for Biomedical Implantable Devices

Application of Transcriptomics for Predicting Protein Interaction Networks, Drug Targets and Drug Candidates

Physician Experience in Technical Success of Achieving NPVR ≥ 80% of High-Intensity Focused Ultrasound Ablation for Uterine Fibroids: A Multicenter Study

Where National Medicines Policies Have Taken Us With Patient Involvement and Health Technology Assessment in Africa

Solving the Evidence Interpretability Crisis in Health Technology Assessment: A Role for Mechanistic Models?

Corrigendum: A Psychometric Platform to Collect Somatosensory Sensations for Neuroprosthetic Use

Electroactive Scaffolds to Improve Neural Stem Cell Therapy for Spinal Cord Injury

Additive Manufacturing of a Miniature Functional Trocar for Eye Surgery

Mechanism-Driven Modeling to Aid Non-invasive Monitoring of Cardiac Function via Ballistocardiography

Editorial: Computational Approaches to Foster Innovation in the Treatment and Diagnosis of Infectious Diseases

Assessment of Smartphone-Based Spiral Tracing in Multiple Sclerosis Reveals Intra-Individual Reproducibility as a Major Determinant of the Clinical Utility of the Digital Test

Reconstructing the Effectiveness of Policy Measures to Avoid Next-Wave COVID-19 Infections and Deaths Using a Dynamic Simulation Model: Implications for Health Technology Assessment

Drug Delivery Systems for the Oral Administration of Antimicrobial Peptides: Promising Tools to Treat Infectious Diseases

Can We Afford to Exclude Patients Throughout Health Technology Assessment?

Patient Involvement in the Health Technology Assessment Process in Taiwan

Editorial: Data-Enabled Intelligence for Medical Technology Innovation, Volume I

In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors