Frontiers in Medical Technology | Pharmaceutical Innovation

Original Research

Published on 30 Jun 2021

Up State of the SARS-COV-2 Spike Homotrimer Favors an Increased Virulence for New Variants

in Pharmaceutical Innovation

Carolina Corrêa Giron
Aatto Laaksonen
Fernando Luís Barroso da Silva

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.694347

6,160 views
28 citations

Review

Published on 24 Jun 2021

Protein-Based Systems for Topical Antibacterial Therapy

in Pharmaceutical Innovation

Raj Kumar Thapa
Krister Gjestvang Grønlien
Hanne Hjorth Tønnesen

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.685686

8,013 views
6 citations

Original Research

Published on 10 Jun 2021

The Development of an ex vivo Flow System to Assess Acute Arterial Drug Retention of Cardiovascular Intravascular Devices

in Pharmaceutical Innovation

Kathryn Cooper
Claire V. Cawthon
Emily Goel
Marzieh Atigh
Uwe Christians
Saami K. Yazdani

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.675188

5,210 views
9 citations

Brief Research Report

Published on 15 Apr 2021

3D Printed Monolithic Device for the Microfluidic Capture, Perfusion, and Analysis of Multicellular Spheroids

in Pharmaceutical Innovation

Alex Markoski
Ian Y. Wong
Jeffrey T. Borenstein

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.646441

5,421 views
7 citations

Review

Published on 12 Apr 2021

Dengue Virus and Vaccines: How Can DNA Immunization Contribute to This Challenge?

in Pharmaceutical Innovation

Ada Maria Barcelos Alves
Simone Morais Costa
Paolla Beatriz Almeida Pinto

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.640964

10,606 views
10 citations

Review

Published on 01 Apr 2021

Review of Kyotorphin Research: A Mysterious Opioid Analgesic Dipeptide and Its Molecular, Physiological, and Pharmacological Characteristics

in Pharmaceutical Innovation

Hiroshi Ueda

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.662697

6,211 views
12 citations

Mini Review

Published on 12 Mar 2021

Developing Antimicrobial Synergy With AMPs

in Pharmaceutical Innovation

Leora Duong
Steven P. Gross
Albert Siryaporn

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.640981

13,434 views
80 citations

Editorial

Published on 26 Feb 2021

Editorial: Tissue Engineering for Drug Discovery and Personalized Medicine

in Pharmaceutical Innovation

Qasem Ramadan
Parveen Sharma

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.663057

3,019 views
2 citations

Original Research

Published on 24 Feb 2021

Bridging the Antimicrobial Activity of Two Lactoferricin Derivatives in E. coli and Lipid-Only Membranes

in Pharmaceutical Innovation

Lisa Marx
Enrico F. Semeraro
Johannes Mandl
Johannes Kremser
Moritz P. Frewein
Nermina Malanovic
Karl Lohner
Georg Pabst

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.625975

3,797 views
21 citations

Original Research

Published on 22 Feb 2021

Modeling Cell Selectivity of Antimicrobial Peptides: How Is the Selectivity Influenced by Intracellular Peptide Uptake and Cell Density

in Pharmaceutical Innovation

Bethany R. Schefter
Shokoofeh Nourbakhsh
Sattar Taheri-Araghi
Bae-Yeun Ha

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.626481

2,902 views
6 citations

Perspective

Published on 16 Feb 2021

Precision Design of Antimicrobial Surfaces

in Pharmaceutical Innovation

Declan C. Mullen
Xing Wan
Timo M. Takala
Per E. Saris
V. M. Moreira

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.640929

3,826 views
6 citations

Data Report

Published on 15 Feb 2021

The SIRAH-CoV-2 Initiative: A Coarse-Grained Simulations' Dataset of the SARS-CoV-2 Proteome

in Pharmaceutical Innovation

Pablo G. Garay
Exequiel E. Barrera
Florencia Klein
Matias R. Machado
Martín Soñora
Sergio Pantano

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.644039

3,053 views
15 citations

Review

Published on 15 Feb 2021

In vitro Models of the Blood–Brain Barrier: Tools in Translational Medicine

in Pharmaceutical Innovation

Alberto Williams-Medina
Michael Deblock
Damir Janigro

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.623950

35,565 views
85 citations

Original Research

Published on 09 Feb 2021

A Comparative Clinical Study of a Novel Pre-colonoscopy Bowel Capsule Preparation Against Two Commercially Available Liquid Preparations

in Pharmaceutical Innovation

Harriet Kingston-Smith
Anoja W. Gunaratne
John Saxon
Sanjay Ramrakha
Marie Vic M. Dawson
Annabel Clancy
Antony Wettstein
Thomas J. Borody

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.622252

4,342 views
4 citations

Mini Review

Published on 04 Feb 2021

Antibiotic Potential and Biophysical Characterization of Amphipathic β-Stranded [XZ]n Peptides With Alternating Cationic and Hydrophobic Residues

in Pharmaceutical Innovation

Erik Strandberg
Parvesh Wadhwani
Anne S. Ulrich

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.622096

2,659 views
6 citations

Review

Published on 28 Jan 2021

3D Bioprinting at the Frontier of Regenerative Medicine, Pharmaceutical, and Food Industries

in Pharmaceutical Innovation

Qasem Ramadan
Mohammed Zourob

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.607648

48,187 views
100 citations

Review

Published on 21 Jan 2021

Spectroscopic and Microscopic Approaches for Investigating the Dynamic Interactions of Anti-microbial Peptides With Membranes and Cells

in Pharmaceutical Innovation

Andrew H. A. Clayton

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.628552

2,810 views
1 citation

Original Research

Published on 13 Jan 2021

Exploring the Association Between Sialic Acid and SARS-CoV-2 Spike Protein Through a Molecular Dynamics-Based Approach

in Pharmaceutical Innovation

Leonardo Bò
Mattia Miotto
Lorenzo Di Rienzo
Edoardo Milanetti
Giancarlo Ruocco

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.614652

5,727 views
36 citations

Mini Review

Published on 11 Jan 2021

Deuterium Solid State NMR Studies of Intact Bacteria Treated With Antimicrobial Peptides

in Pharmaceutical Innovation

Valerie Booth

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.621572

3,725 views
12 citations

Review

Published on 21 Dec 2020

Revealing the Mechanisms of Synergistic Action of Two Magainin Antimicrobial Peptides

in Pharmaceutical Innovation

Burkhard Bechinger
Dennis Wilkens Juhl
Elise Glattard
Christopher Aisenbrey

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.615494

8,002 views
49 citations

Mini Review

Published on 17 Dec 2020

In-cell Solid-State NMR Studies of Antimicrobial Peptides

in Pharmaceutical Innovation

Frances Separovic
David W. Keizer
Marc-Antoine Sani

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.610203

4,789 views
18 citations

Mini Review

Published on 15 Dec 2020

Application of Biophysical Techniques to Investigate the Interaction of Antimicrobial Peptides With Bacterial Cells

in Pharmaceutical Innovation

Maria Luisa Gelmi
Luca Domenico D'Andrea
Alessandra Romanelli

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.606079

4,185 views
4 citations

Review

Published on 15 Dec 2020

Immunotherapeutic Activities of a DNA Plasmid Carrying the Mycobacterial hsp65 Gene (DNAhsp65)

in Pharmaceutical Innovation

Celio Lopes Silva
Thiago Malardo
Aline Seiko Carvalho Tahyra

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.603690

2,652 views
3 citations

Mini Review

Published on 11 Dec 2020

Mode-of-Action of Antimicrobial Peptides: Membrane Disruption vs. Intracellular Mechanisms

in Pharmaceutical Innovation

Aurélie H. Benfield
Sónia Troeira Henriques

Frontiers in Medical Technology

doi 10.3389/fmedt.2020.610997

49,494 views
305 citations

59 articles

articles

Up State of the SARS-COV-2 Spike Homotrimer Favors an Increased Virulence for New Variants

Protein-Based Systems for Topical Antibacterial Therapy

The Development of an ex vivo Flow System to Assess Acute Arterial Drug Retention of Cardiovascular Intravascular Devices

3D Printed Monolithic Device for the Microfluidic Capture, Perfusion, and Analysis of Multicellular Spheroids

Dengue Virus and Vaccines: How Can DNA Immunization Contribute to This Challenge?

Review of Kyotorphin Research: A Mysterious Opioid Analgesic Dipeptide and Its Molecular, Physiological, and Pharmacological Characteristics

Developing Antimicrobial Synergy With AMPs

Editorial: Tissue Engineering for Drug Discovery and Personalized Medicine

Bridging the Antimicrobial Activity of Two Lactoferricin Derivatives in E. coli and Lipid-Only Membranes

Modeling Cell Selectivity of Antimicrobial Peptides: How Is the Selectivity Influenced by Intracellular Peptide Uptake and Cell Density

Precision Design of Antimicrobial Surfaces

The SIRAH-CoV-2 Initiative: A Coarse-Grained Simulations' Dataset of the SARS-CoV-2 Proteome

In vitro Models of the Blood–Brain Barrier: Tools in Translational Medicine

A Comparative Clinical Study of a Novel Pre-colonoscopy Bowel Capsule Preparation Against Two Commercially Available Liquid Preparations

Antibiotic Potential and Biophysical Characterization of Amphipathic β-Stranded [XZ]n Peptides With Alternating Cationic and Hydrophobic Residues

3D Bioprinting at the Frontier of Regenerative Medicine, Pharmaceutical, and Food Industries

Spectroscopic and Microscopic Approaches for Investigating the Dynamic Interactions of Anti-microbial Peptides With Membranes and Cells

Exploring the Association Between Sialic Acid and SARS-CoV-2 Spike Protein Through a Molecular Dynamics-Based Approach

Deuterium Solid State NMR Studies of Intact Bacteria Treated With Antimicrobial Peptides

Revealing the Mechanisms of Synergistic Action of Two Magainin Antimicrobial Peptides

In-cell Solid-State NMR Studies of Antimicrobial Peptides

Application of Biophysical Techniques to Investigate the Interaction of Antimicrobial Peptides With Bacterial Cells

Immunotherapeutic Activities of a DNA Plasmid Carrying the Mycobacterial hsp65 Gene (DNAhsp65)

Mode-of-Action of Antimicrobial Peptides: Membrane Disruption vs. Intracellular Mechanisms