Frontiers in Medicine

Brief Research Report

Published on 17 Dec 2025

Cryopreserved exosomes derived from hypoxic Wharton’s jelly mesenchymal stromal cells enhance fibroblast proliferation, upregulate COL1A2 expression, and mitigate senescence

in Translational Medicine

Carolina Quintero-Gil
Wendy Jaraba-Alvarez
Juan P Franco-Salazar
Yurany Blanquiceth
Ferley A Bedoya-Guzmán
Sofía Ortiz-Tamayo
Natalia Quiroz-Correa
Vanesa Sanchez-Giraldo
Karolynn Halpert
Héctor Ortega-Arellano

Frontiers in Medicine

doi 10.3389/fmed.2025.1692585

559 views

Original Research

Published on 17 Dec 2025

In the era of copy number variation sequencing: changes in the target population for prenatal diagnosis and what is the optimal prenatal diagnostic strategy?

in Obstetrics and Gynecology

Shaozhe Yang
Rongxiang Li
Shuwen Xin
Yanqi He
Shaoxia Teng
Yanan Gao
Xiuhong Fu

Frontiers in Medicine

doi 10.3389/fmed.2025.1610477

490 views

Original Research

Published on 17 Dec 2025

Clinical impact of child life intervention combined with comprehensive nutrition intervention on pain management, nutritional status, and treatment compliance in school-age children with limb fractures

in Family Medicine and Primary Care

Qin Zhang
Fangqin Jin
Jiangping Weng
Xuting Pan
Qinyan Dong
Yuping Zhao
Jiaojiao Sheng

Frontiers in Medicine

doi 10.3389/fmed.2025.1658982

371 views

Original Research

Published on 17 Dec 2025

Comparative analysis of clinical feature–based machine learning models for predicting myofascial pelvic pain syndrome: a single-center retrospective study

in Obstetrics and Gynecology

Zhuyin Li
Wenjing Li
Jie Huang
Shuangyu Zhang
Ruolin Jia
Dongxia Liu
Yanhua Dong
Hongguo Zhao
Manman Nai
Lei Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1689480

420 views

Original Research

Published on 17 Dec 2025

Association between prealbumin levels and the risk of osteoporosis among individuals aged 50 and above in Southwest China: a retrospective case–control study

in Geriatric Medicine

Xu Zhao
Chenhui Cai
Chao Tang
Zaoqing Zhang
Xianming Huang
Tongwei Chu

Frontiers in Medicine

doi 10.3389/fmed.2025.1695044

488 views

Original Research

Published on 17 Dec 2025

Immuno-protective impact of Kangfuxin liquid on systematic toxicity associated with autologous hematopoietic stem cell transplantation in multiple myeloma

in Hematology

Xianyi Wu
Mingxuan Tang
Taohua Deng
Fujun Qu
Fang Jiang
Qin Zhou
Wenyuan Lin
Xiaotao Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1700829

554 views

Case Report

Published on 17 Dec 2025

A case report of neoadjuvant targeted therapy in stage IIIA non-small cell lung cancer with BRAF V600E mutation

in Precision Medicine

Wenying Peng
Susu Qu
Lijuan Cai
Runxiang Yang
Mengyuan Dong
Xiang Li
Fengming Ran
Chunxiang Luo

Frontiers in Medicine

doi 10.3389/fmed.2025.1664182

593 views

Original Research

Published on 17 Dec 2025

Ultrasonographic features of IgG4-related kidney disease: diagnostic value and correlation with clinical-pathological findings

in Nephrology

Boxiong Wei
Yi Liu
Suxia Wang
Yuhong Shao
Xiuming Sun
Luzeng Chen
Xiumei Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1664308

513 views

Original Research

Published on 17 Dec 2025

Construction and validation of nomogram prediction model for recurrent spontaneous abortion based on the expression of MALAT1, miR-515-5p, and MCL1 mRNA

in Obstetrics and Gynecology

Xufei Chen
Xiaotong Wang
Yuyi Yuan
Shuzhen He
Huanhuan Huang
Chunhua Zhong

Frontiers in Medicine

doi 10.3389/fmed.2025.1558818

479 views

Editorial

Published on 17 Dec 2025

Editorial: Exploring immunometabolism: metabolic pathway and immune response in sepsis

in Intensive Care Medicine and Anesthesiology

Yuan Yuan
Lulong Bo
Ruoxi Zhang
Feng Chen

Frontiers in Medicine

doi 10.3389/fmed.2025.1758108

451 views

Original Research

Accepted on 16 Dec 2025

Educational Performance of TikTok Short Videos for Age Related Macular Degeneration and Its Link to User Engagement

in Ophthalmology

Ligang Jiang
Xin Jiang
Xia Shi
Xinya Hu
Chunyan Song
Weihua Yang
Yuhua Tong

Frontiers in Medicine

239 views

Original Research

Accepted on 16 Dec 2025

Comparative Morphological Analysis of the Zonular Apparatus in Porcine, Feline, and Canine Species

in Ophthalmology

Ye Lu
Kuankuan Wu
Zhiqiao Liang
Kun Lv
Zeyuan Wang
Fengrui Yang
Yitong Hu
Huijuan Wu

Frontiers in Medicine

240 views

Original Research

Accepted on 16 Dec 2025

Incidence of eye problems in children aged 3-6 years during and after the COVID-19 pandemic

in Ophthalmology

Peng Ye
Ying Zhang
Yunrong Fu
Peiling Cai
Yu Xie
Xinwei Chen
Mengping Wang
Mingyue Zhang
Ronglian Guo

Frontiers in Medicine

229 views

Review

Accepted on 16 Dec 2025

The Forgotten Airway: Central Airway Pathology in the ICU

in Pulmonary Medicine

Alessandro Marchioni
Antonio Moretti
Luca Tabbi'
Francesco Livrieri
Martina Tartaglia
Michele Gentile
Alberto Scorsone
Francesco Mattioli
Roberto Tonelli
Enrico M. Clini

Frontiers in Medicine

232 views

Original Research

Accepted on 16 Dec 2025

A Patient Journey Mapping Study of Lived Experiences during Platelet-Rich Fibrin Gel Therapy for Venous Leg Ulcers

in Dermatology

Feifei Cui
Zhen Xu
Rongting Wang
Shuainan Chen
Qiaodan Hu
Haiying Wu

Frontiers in Medicine

Original Research

Accepted on 16 Dec 2025

A Foundation Model-Driven Multi-View Collaborative Framework for Semi-Supervised 3D Medical Image Segmentation

in Nuclear Medicine

Li Lina
Bin Wang
Hong Zhang

Frontiers in Medicine

145 views

Original Research

Accepted on 16 Dec 2025

BOBM: an adaptive deep learning framework for extended-window sepsis prediction with cross-institutional generalizability

in Intensive Care Medicine and Anesthesiology

Wanxuan Li
Kai Xiao
Boyuan Gu
Haoyu Zheng
Ren Mo
Qiong Yang

Frontiers in Medicine

223 views

Systematic Review

Accepted on 16 Dec 2025

The Efficacy and Safety of Omalizumab in the Treatment of Asthma: An Overview of Systematic Reviews and Meta Analyses

in Pulmonary Medicine

Dongze Li
Zhuang Wang
Lijie Hou
NA WANG
Bing Tian
Xiaofei Xie
Yinan Guo
Yongji Wang

Frontiers in Medicine

Original Research

Accepted on 16 Dec 2025

Clinical and Demographic Characteristics of Patients Presenting with Post-Infectious Bronchial Hyperresponsiveness at a Pulmonology Clinic

in Pulmonary Medicine

Nazlı Zeynep Uslu
Bensu Tanışman
Ebru Zeynep Delikanlı
Ayşenur Gençalp
Irem Karaman
Sebahat Dilek Torun
Merih Kalamanoğlu Balcı

Frontiers in Medicine

160 views

Original Research

Accepted on 16 Dec 2025

Comparison of Automated Ultrasound Pupillometry Assessment Versus Infrared Pupillary in Critically Ill Patients

in Intensive Care Medicine and Anesthesiology

Weiting Chen
Xiaoshuang Jiang
Xixi Guo
Jiuzhou Lin
Min Tang
Nanlin Dou

Frontiers in Medicine

Case Report

Accepted on 16 Dec 2025

Multifactorial Weaning Failure After Lung Transplantation in Paraquat-Induced Pulmonary Fibrosis: A Case-Based Clinical Review

in Intensive Care Medicine and Anesthesiology

Xin Xia
Yue Xing
Tianjun Zhou
Xiaosong Ben
Weifeng Zhan

Frontiers in Medicine

127 views

Original Research

Accepted on 16 Dec 2025

Vitamin B12 Injection Plus Traditional Chinese Medicine Techniques for Meralgia Paresthetica: A Randomized Controlled Trial

in Family Medicine and Primary Care

Hongxia Guan
Yong Shi
Xia Zhao

Frontiers in Medicine

132 views

Mini Review

Accepted on 16 Dec 2025

Making Chatbots More Human: Deep Reasoning Large Language Models in Ophthalmology

in Ophthalmology

Yizhou Yang
Yuecheng Ren
Xuanqiao Lin

Frontiers in Medicine

182 views

Systematic Review

Accepted on 16 Dec 2025

Effects of different prehabilitation programs on the major abdominal surgery population: A systematic review and network meta-analysis

in Healthcare Professions Education

Yue Sun
Wenchao Mao
Yaoyuan Li
Yan Sun
Kaixuan Li
Zheng Wang
Dongpo Zhang
Hengxin Bai
Han Xia
Xiaoli Zhang

Frontiers in Medicine

20,265 articles

articles

Cryopreserved exosomes derived from hypoxic Wharton’s jelly mesenchymal stromal cells enhance fibroblast proliferation, upregulate COL1A2 expression, and mitigate senescence

In the era of copy number variation sequencing: changes in the target population for prenatal diagnosis and what is the optimal prenatal diagnostic strategy?

Clinical impact of child life intervention combined with comprehensive nutrition intervention on pain management, nutritional status, and treatment compliance in school-age children with limb fractures

Comparative analysis of clinical feature–based machine learning models for predicting myofascial pelvic pain syndrome: a single-center retrospective study

Association between prealbumin levels and the risk of osteoporosis among individuals aged 50 and above in Southwest China: a retrospective case–control study

Immuno-protective impact of Kangfuxin liquid on systematic toxicity associated with autologous hematopoietic stem cell transplantation in multiple myeloma

A case report of neoadjuvant targeted therapy in stage IIIA non-small cell lung cancer with BRAF V600E mutation

Ultrasonographic features of IgG4-related kidney disease: diagnostic value and correlation with clinical-pathological findings

Construction and validation of nomogram prediction model for recurrent spontaneous abortion based on the expression of MALAT1, miR-515-5p, and MCL1 mRNA

Editorial: Exploring immunometabolism: metabolic pathway and immune response in sepsis

Educational Performance of TikTok Short Videos for Age Related Macular Degeneration and Its Link to User Engagement

Comparative Morphological Analysis of the Zonular Apparatus in Porcine, Feline, and Canine Species

Incidence of eye problems in children aged 3-6 years during and after the COVID-19 pandemic

The Forgotten Airway: Central Airway Pathology in the ICU

A Patient Journey Mapping Study of Lived Experiences during Platelet-Rich Fibrin Gel Therapy for Venous Leg Ulcers

A Foundation Model-Driven Multi-View Collaborative Framework for Semi-Supervised 3D Medical Image Segmentation

BOBM: an adaptive deep learning framework for extended-window sepsis prediction with cross-institutional generalizability

The Efficacy and Safety of Omalizumab in the Treatment of Asthma: An Overview of Systematic Reviews and Meta Analyses

Clinical and Demographic Characteristics of Patients Presenting with Post-Infectious Bronchial Hyperresponsiveness at a Pulmonology Clinic

Comparison of Automated Ultrasound Pupillometry Assessment Versus Infrared Pupillary in Critically Ill Patients

Multifactorial Weaning Failure After Lung Transplantation in Paraquat-Induced Pulmonary Fibrosis: A Case-Based Clinical Review

Vitamin B12 Injection Plus Traditional Chinese Medicine Techniques for Meralgia Paresthetica: A Randomized Controlled Trial

Making Chatbots More Human: Deep Reasoning Large Language Models in Ophthalmology

Effects of different prehabilitation programs on the major abdominal surgery population: A systematic review and network meta-analysis