Frontiers in Medicine | Infectious Diseases: Pathogenesis and Therapy

Original Research

Accepted on 09 Dec 2025

Machine learning-based approach to guide the choice between baricitinib and tocilizumab in critical COVID-19 pneumonia treatment: a retrospective cohort study

in Infectious Diseases: Pathogenesis and Therapy

Euijin Chang
Myung-Soo Kim
Se Yoon Park
Kyungsup Kwon
Hyeon-Mu Jang
So Yun Lim
Seongman Bae
Jiwon Jung
Min Jae Kim
Yong Pil Chong

Frontiers in Medicine

126 views

Perspective

Accepted on 09 Dec 2025

The development of therapeutic strategy for post acute sequelae of COVID19 should be based on an efficient classification of pathogenesis

in Infectious Diseases: Pathogenesis and Therapy

Heng Wang
Li Shen
Song Xue

Frontiers in Medicine

134 views

Original Research

Published on 09 Dec 2025

Comparison of antibiotic resistance and molecular characteristics of Escherichia coli isolated from patients with UTI, ASB, and uropathic bloodstream infection

in Infectious Diseases: Pathogenesis and Therapy

Sipei Wang
Sheng Zhao
Tinghua Ye
Xingxing Lou
Xinling Pan

Frontiers in Medicine

doi 10.3389/fmed.2025.1678401

624 views

Systematic Review

Published on 09 Dec 2025

Central nervous system symptoms in mpox patients without HIV co-infection: a meta-analysis

in Infectious Diseases: Pathogenesis and Therapy

Junwen Luan
Weimiao Lv
Xiaoyan Wang
Yuxuan Du
Xuejia Wang
Leiliang Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1672518

489 views

Original Research

Published on 09 Dec 2025

Worldwide distribution of human pythosis and biological characteristics of a Pythium insidiosum strain susceptible to antibiotics from China: a dual-scale study

in Infectious Diseases: Pathogenesis and Therapy

Xiaoyun Liu
Qiuyue Diao
Mingliang Li
Yuting Yang
Jiayin Liang
Zehua Cui
Haiyan Zhang
Huiling He
Jiabao Huang
Hao Ren

Frontiers in Medicine

doi 10.3389/fmed.2025.1629018

453 views

Case Report

Accepted on 08 Dec 2025

Case Report: massive subcapsular hepatic hematoma after spontaneous rupture of pyogenic liver abscess in a healthy young woman

in Infectious Diseases: Pathogenesis and Therapy

Jiaqi Chen
Zejin Zhao
Kunyu Huang
Liyong Zhang
JinHua Cui
Ziyu Bai
Aijun Yu
Jian Li
Zhuqing Zhang
Kai Chen

Frontiers in Medicine

Case Report

Published on 08 Dec 2025

Spinal infection caused by Aspergillus terreus in immunocompetent individuals: a case report and literature review

in Infectious Diseases: Pathogenesis and Therapy

Lingling Liu
Meijuan Pei
Yijie Ma
Xu Guo
Shuai Guo
Haolin Sun
Junqi Zheng
Xueyuan Su
Lihua Meng
Xiaodong Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1701261

455 views

Original Research

Published on 08 Dec 2025

Expanding the spectrum of chronic hepatitis E in kidney transplantation: first report of HEV-3ra infection and review of literature

in Infectious Diseases: Pathogenesis and Therapy

Emanuel F. Matias
Mariana Azevedo
Susana Sampaio
Ana Teresa Pinho
Silvia Conde
Sandra Rebelo
Sérgio Santos-Silva
Maria S. J. Nascimento
João R. Mesquita
Lurdes Santos

Frontiers in Medicine

doi 10.3389/fmed.2025.1705331

534 views

Original Research

Accepted on 05 Dec 2025

Solving the Diagnostic Dilemma in Bone Infections: Metagenomic Next Generation Sequencing Enhances Pathogen Identification Accuracy

in Infectious Diseases: Pathogenesis and Therapy

Jiheng Xiao
Congli Pu
Xianglong Zhou
Xiaokang Zhang
Shanshan Zhang
Puxin Yang
Yingze Zhang
Liming Xiong

Frontiers in Medicine

186 views

Correction

Accepted on 05 Dec 2025

Correction: A rare case of Clostridium paraputrificum bloodstream infection in a patient with intestinal necrosis: case report and literature review

in Infectious Diseases: Pathogenesis and Therapy

Frontiers Production Office

Frontiers in Medicine

134 views

Case Report

Accepted on 05 Dec 2025

Rifampin Monotherapy for Multidrug-Resistant Chryseobacterium indologenes Meningitis Unresponsive to Trimethoprim-Sulfamethoxazole: A Case Report and Review of the Literature

in Infectious Diseases: Pathogenesis and Therapy

Dongchuan Shao
Zhe Li
Zhiwei Cao
Zhou Yang
Wenbiao Huang
Kuairong Pu
Jun Wu
Nan Zhao

Frontiers in Medicine

148 views

Systematic Review

Accepted on 05 Dec 2025

Association Between Stress Hyperglycemia Ratio and All-Cause Mortality Among ICU Patients With Sepsis: A Systematic Review and Meta-Analysis

in Infectious Diseases: Pathogenesis and Therapy

Haohao Xie
Tian Hao
Ruirui Qi
Lin Zhang
Donghui Jia
Hengyang Wang
Wenxiu Niu
Xiaomeng Han
Yuhan Sha
Zhigang Zhang

Frontiers in Medicine

Original Research

Published on 05 Dec 2025

Development of a laboratory-based nomogram for predicting clinical outcomes in patients with severe COVID-19 undergoing glucocorticoid therapy

in Infectious Diseases: Pathogenesis and Therapy

Langqing Xu
Chunyang Hou
Jing Jie
Zhifang Jia
Lei Song
Dan Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1635545

571 views

Systematic Review

Published on 05 Dec 2025

Historical evolution, research hotspots and emerging trends of pediatric hand, foot, and mouth disease: a bibliometric worldview since the 21st century

in Infectious Diseases: Pathogenesis and Therapy

Lei Liang
Yujing Zhang
Xinxin Zhang
Xuran Guo
Yongbin Yan

Frontiers in Medicine

doi 10.3389/fmed.2025.1722750

1,013 views

Case Report

Published on 05 Dec 2025

Case Report: Exclusive localization of Leishman-Donovan bodies in neutrophils on peripheral blood smear in a patient with systemic lupus erythematosus

in Infectious Diseases: Pathogenesis and Therapy

Fucun Ma
Ruixue Zhang
Meilin He
Jia Li
Mingjian Bai
Guowei Liang
Xuekai Liu

Frontiers in Medicine

doi 10.3389/fmed.2025.1693178

457 views

Systematic Review

Published on 05 Dec 2025

Determinants of pneumococcal carriage by age in Africa (2000–2021): a systematic analysis

in Infectious Diseases: Pathogenesis and Therapy

Eliza Mari Kwesi-Maliepaard
Nicholas Kwasi-Do Ohene Opoku
Beverly Egyir
Nicholas TKD Dayie
Kwadwo Asamoah Kusi
Augustina Frimpong

Frontiers in Medicine

doi 10.3389/fmed.2025.1683313

809 views

Case Report

Published on 04 Dec 2025

Chronic meningoencephalomyelitis caused by Nocardia nova infection: a case report and literature review

in Infectious Diseases: Pathogenesis and Therapy

Shao Li
Qianqian Tian
Xixi Yang
Mengyao Zhang
Menghan Zheng
Dawei Li
Zhihui Duan
Yan Li
Zhandong Qiu
Zheng Liu

Frontiers in Medicine

doi 10.3389/fmed.2025.1680771

565 views

Case Report

Published on 04 Dec 2025

Successful ventilator weaning after aerosolized liposomal amphotericin B in persistent Candida glabrata colonization: a case report

in Infectious Diseases: Pathogenesis and Therapy

Massimo Caracciolo
Simona Pellicano
Sarah Antonella Caracciolo
Maria Francesca Stagno
Antonino Ripepi
Selma Valerie Mammone
Nadia Pellicano
Stefano La Scala
Giuseppe Mazza
Giuseppe Neri

Frontiers in Medicine

doi 10.3389/fmed.2025.1697842

810 views

Case Report

Published on 04 Dec 2025

Case Report: Peritoneal dialysis-associated peritonitis caused by Brucella

in Infectious Diseases: Pathogenesis and Therapy

Shu-fang Pan
Munire Abulizi
Adili Sawuti
Su-ying Han
Maimaitiaili Tuerxun
Jian-yun Zhu
Cai-lian Cheng

Frontiers in Medicine

doi 10.3389/fmed.2025.1722094

459 views

Case Report

Published on 04 Dec 2025

Mollaret meningitis: a case report and literature review

in Infectious Diseases: Pathogenesis and Therapy

Yi-da Wang
Zun-jing Liu
Cheng-yue Sun
Huai-lian Guo
Hong Jiang

Frontiers in Medicine

doi 10.3389/fmed.2025.1719046

527 views

Brief Research Report

Accepted on 03 Dec 2025

Genetic patterns related to von Willebrand Factor: implications on the need for mechanical ventilation, severity and death in COVID-19

in Infectious Diseases: Pathogenesis and Therapy

José López Castro
Silvia Diz-de Almeida
Manuel L. López Reboiro
Cristina Sardiña González
José A. Riancho
Augusto Rojas-Martinez
Pablo Lapunzina
Carlos Flores
RAQUEL CRUZ GUERRERO
Angel Carracedo

Frontiers in Medicine

158 views

Case Report

Published on 03 Dec 2025

A rare case of Clostridium paraputrificum bloodstream infection in a patient with intestinal necrosis: case report and literature review

in Infectious Diseases: Pathogenesis and Therapy

Caixia Ji
Ke Wang
Zongyao Chen
E. Jianfei
Yayun Jiang
Ziqian Huang
Wei Huang

Frontiers in Medicine

doi 10.3389/fmed.2025.1702526

621 views

Brief Research Report

Published on 02 Dec 2025

HIV-associated CD8+ encephalitis confirmed by cerebrospinal fluid flow cytometry: first case in Colombia

in Infectious Diseases: Pathogenesis and Therapy

Nicolas Soto-Moreno
Nicole Pinzon
Natalia Echandia
Omar Rojas-Tabares
Marcela Yanguma
Laura Oviedo
Michael Ariza-Varón

Frontiers in Medicine

doi 10.3389/fmed.2025.1702506

821 views

Case Report

Accepted on 01 Dec 2025

First case report of Shewanella indica isolated from a hospitalized patient in Serbia

in Infectious Diseases: Pathogenesis and Therapy

Brankica Filipić
Vladimir Žugić
Majda Golob
Martina Hrast Rambaher
Lidija Bošković
Marina T Milenković

Frontiers in Medicine

1,291 articles

articles

Machine learning-based approach to guide the choice between baricitinib and tocilizumab in critical COVID-19 pneumonia treatment: a retrospective cohort study

The development of therapeutic strategy for post acute sequelae of COVID19 should be based on an efficient classification of pathogenesis

Comparison of antibiotic resistance and molecular characteristics of Escherichia coli isolated from patients with UTI, ASB, and uropathic bloodstream infection

Central nervous system symptoms in mpox patients without HIV co-infection: a meta-analysis

Worldwide distribution of human pythosis and biological characteristics of a Pythium insidiosum strain susceptible to antibiotics from China: a dual-scale study

Case Report: massive subcapsular hepatic hematoma after spontaneous rupture of pyogenic liver abscess in a healthy young woman

Spinal infection caused by Aspergillus terreus in immunocompetent individuals: a case report and literature review

Expanding the spectrum of chronic hepatitis E in kidney transplantation: first report of HEV-3ra infection and review of literature

Solving the Diagnostic Dilemma in Bone Infections: Metagenomic Next Generation Sequencing Enhances Pathogen Identification Accuracy

Correction: A rare case of Clostridium paraputrificum bloodstream infection in a patient with intestinal necrosis: case report and literature review

Rifampin Monotherapy for Multidrug-Resistant Chryseobacterium indologenes Meningitis Unresponsive to Trimethoprim-Sulfamethoxazole: A Case Report and Review of the Literature

Association Between Stress Hyperglycemia Ratio and All-Cause Mortality Among ICU Patients With Sepsis: A Systematic Review and Meta-Analysis

Development of a laboratory-based nomogram for predicting clinical outcomes in patients with severe COVID-19 undergoing glucocorticoid therapy

Historical evolution, research hotspots and emerging trends of pediatric hand, foot, and mouth disease: a bibliometric worldview since the 21st century

Case Report: Exclusive localization of Leishman-Donovan bodies in neutrophils on peripheral blood smear in a patient with systemic lupus erythematosus

Determinants of pneumococcal carriage by age in Africa (2000–2021): a systematic analysis

Chronic meningoencephalomyelitis caused by Nocardia nova infection: a case report and literature review

Successful ventilator weaning after aerosolized liposomal amphotericin B in persistent Candida glabrata colonization: a case report

Case Report: Peritoneal dialysis-associated peritonitis caused by Brucella

Mollaret meningitis: a case report and literature review

Genetic patterns related to von Willebrand Factor: implications on the need for mechanical ventilation, severity and death in COVID-19

A rare case of Clostridium paraputrificum bloodstream infection in a patient with intestinal necrosis: case report and literature review

HIV-associated CD8+ encephalitis confirmed by cerebrospinal fluid flow cytometry: first case in Colombia

First case report of Shewanella indica isolated from a hospitalized patient in Serbia